Review
Anesthesiology
Guillaume Christe, Geert Crombez, Shannon Edd, Emmanuelle Opsommer, Brigitte M. Jolles, Julien Favre
Summary: Higher levels of pain-related fear, catastrophizing, and depression are significantly associated with reduced spinal movement amplitudes and increased muscle activity in low back pain patients. Pain intensity has a minimal independent association with spinal motor behavior, and the small effect sizes found in the meta-analyses question the role of psychological factors as major causes of spinal movement avoidance.
Article
Psychology, Clinical
Paul W. Marshall, Natalie M. V. Morrison, Mitchell Gibbs, Siobhan M. Schabrun
Summary: This study followed 400 people with chronic low back pain for 1 year and found that exercise can reduce disability through the effect on pain and catastrophizing.
BEHAVIOUR RESEARCH AND THERAPY
(2022)
Review
Clinical Neurology
Sanaz Shanbehzadeh, Shabnam ShahAli, Isamael Ebrahimi Takamjani, Johan W. S. Vlaeyen, Reza Salehi, Hassan Jafari
Summary: The study found negative correlations between pain-related threat beliefs or disability and lumbar range of motion in individuals with low back pain. However, the correlations between pain-related threat beliefs and postural control during static standing were not significant. Moderate negative correlations between disability and postural control were observed in some studies.
EUROPEAN SPINE JOURNAL
(2022)
Article
Clinical Neurology
Mulualem Yihunie, Yohannes Abich, Solomon Fasika Demissie, Tesfa Kassa, Parthasarathy Ranganathan, Balamurugan Janakiraman
Summary: This study describes fear-avoidance beliefs about physical activity among adults with chronic low back pain and explores its association with socio-demographic and clinical factors. The findings suggest that fear-avoidance beliefs are associated with residence, work, and medication intake. These findings can further guide future research and assist clinicians in choosing appropriate interventions for different subgroups.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Orthopedics
Maria Andre, Mari Lundberg
Summary: The study explores thoughts and ideas about body and pain in patients with nonspecific low back pain who have fear of movement. Findings suggest that patients with fear require support to feel secure and have enough confidence in their body to move and exercise. Clinicians need to better incorporate evidence-based practice and provide updated information for patients with recurrent LBP and fear.
Review
Medicine, General & Internal
Nebojsa Nick Knezevic, Kenneth D. Candido, Johan W. S. Vlaeyen, Jan Van Zundert, Steven P. Cohen
Summary: Low back pain encompasses various types of pain, with diagnostic and therapeutic methods controversial, requiring a comprehensive approach considering biological, psychological, and social factors. Improvement in diagnostic accuracy, treatment algorithms, and multimodal interdisciplinary treatment are essential.
Article
Chemistry, Multidisciplinary
Josce Syrett, David W. Evans, Bernard X. W. Liew
Summary: The study aimed to investigate the influence of weightlifting/powerlifting (WL/PL) on low back pain (LBP) beliefs and pain-related fear, as well as the potential impact of training, individual, and injury characteristics on these psychological factors. Questionnaire scores were collected from 67 WL/PL participants using the Photographic Series of Daily Activities-Short Electronic Version (PHODA-SeV) and the Back Pain and Attitudes Questionnaire (Back-PAQ). The study found that only the Back-PAQ score was significantly lower than the published score of 113. Male participants had a significantly lower PHODA-SeV score compared to females. The back squat weight was identified as an important factor associated with both PHODA-SeV and Back-PAQ scores. Further research is needed to investigate the potential benefits of WL/PL training in reducing pain-related fear and beliefs and preventing LBP.
APPLIED SCIENCES-BASEL
(2023)
Review
Anesthesiology
Van Bogaert Wouter, Tegner Heidi, Coppieters Iris, Huysmans Eva, Nijs Jo, Moens Maarten, Goudman Lisa, Buyl Ronald, Lundberg Mari
Summary: This systematic review evaluated the predictive value of preoperative fear avoidance beliefs for postoperative outcomes following surgery for lumbar degenerative disease. The review found moderate evidence indicating that preoperative pain-related fear is not a significant predictor for postoperative pain and function. Limited evidence was found for the lack of predictive value of preoperative pain catastrophizing for postoperative health-related quality of life.
Review
Clinical Neurology
Rupal M. Patel, Bethany L. Anderson, John B. Bartholomew
Summary: Pain catastrophizing is a maladaptive cognitive strategy that complicates recovery and pain management for patients undergoing total knee replacement. Several interventions show modest benefits in reducing pain catastrophizing, but further research is needed for clinical decision-making support.
JOURNAL OF PAIN RESEARCH
(2022)
Article
Psychology, Clinical
Vera Vergeld, Kathleen A. Martin Ginis, Alan D. Jenks
Summary: Research suggests that psychological interventions such as cognitive behavior therapy and psychoeducation can be effective in addressing fear avoidance beliefs among patients with chronic back pain. However, there is inconsistent evidence regarding the most effective psychological interventions for treating fear avoidance beliefs in this population.
REHABILITATION PSYCHOLOGY
(2021)
Article
Psychiatry
Xiang Zhao, Katja Boersma, Bjorn Gerdle, Peter Molander, Hugo Hesser
Summary: This study used network analysis to explore the complex relationships among psychological constructs related to the fear-avoidance model in patients with chronic pain. The study found strong associations between pain intensity, pain interference, fear of movement, and pain catastrophizing. Furthermore, the relationships between these constructs varied depending on the extent of pain experienced by the patients.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Multidisciplinary Sciences
Aminu Alhassan Ibrahim, Mukadas Oyeniran Akindele, Sokunbi Oluwaleke Ganiyu, Bashir Kaka, Bashir Bello
Summary: The study successfully translated and culturally adapted the BBQ into Hausa language and assessed its psychometric properties in mixed urban and rural Nigerian populations with chronic LBP. Results showed that the Hausa-BBQ had good internal and external construct validity, internal consistency, and test-retest reliability, making it a useful tool for detecting specific attitudes and beliefs about back pain in the Hausa culture.
Review
Psychology, Clinical
Cheryl H. T. Chow, Christy Yu, Wei Yu, Klement Yeung, Louis A. Schmidt, Norman Buckley
Summary: This study aimed to identify perioperative and psychosocial factors associated with Acute Postsurgical Pain (APSP) severity in pediatric patients undergoing surgery. Through the analysis of 38 studies, it was found that factors such as child preoperative pain, pain immediately after surgery, anticipated pain, temperament, pain catastrophizing, age, preoperative anxiety, parent pain catastrophizing, and parent preoperative anxiety were positively associated with APSP, while child pain coping efficacy was protective against APSP. Early interventions can help reduce pain burden and enhancing coping abilities may also reduce APSP occurrence.
Article
Rehabilitation
Mette Hoj Skovbo, Karina Agerbo, Anna Jakobsen, Stine Aalkjaer Clausen, Vivian Langagergaard, Nanna Rolving
Summary: This study presented a group-based pain management programme for patients with persistent non-specific low back pain, utilizing a cognitive-behavioral approach. The theoretical rationale was based on the Fear-avoidance model and the Self-efficacy Theory, with expected outcomes including changes in disability, quality of life, sick leave and physical activity. The intervention, consisting of six sessions, was developed and tested in a pilot study, with final content and educational materials completed for further evaluation in a randomized controlled trial.
CLINICAL REHABILITATION
(2021)
Article
Anesthesiology
David Murray Klyne, Leanne Marie Hall, Michael K. Nicholas, Paul William Hodges
Summary: Early identification of depressive symptoms and healthcare utilization predicted worse and better outcomes in acute low back pain, respectively. Gender and BMI inconsistently predicted outcomes. Time variation of risk factors should be considered in assessing poor outcome risk.
EUROPEAN JOURNAL OF PAIN
(2022)
Article
Medicine, General & Internal
Adriana Wirth, Andrea Goetschi, Ulrike Held, Ataman Sendoel, Melina Stuessi-Helbling, Lars Christian Huber
Summary: This study aimed to validate the 4C Deterioration Model and 4C Mortality Score for COVID-19 patients and found that the inclusion of NLR did not improve the model performance.
Article
Psychology, Clinical
Eileen Krinke, Ulrike Held, Klaus Steigmiller, Kim Felmingham, Birgit Kleim
Summary: This study examined the associations between sex hormones and cortisol during memory consolidation and the development of intrusive memories. The results showed that higher progesterone levels and lower estradiol levels predicted more intrusive memories. Further research is needed to better understand the roles of gonadal and adrenal hormones in trauma memory formation and their influence on the development of PTSD.
EUROPEAN JOURNAL OF PSYCHOTRAUMATOLOGY
(2022)
Article
Clinical Neurology
Kevin Akeret, Raphael M. Buzzi, Moritz Saxenhofer, Kathrin Bieri, Deborah Chiavi, Bart R. Thomson, Manuela Gruttner-Durmaz, Nina Schwendinger, Rok Humar, Luca Regli, Tristan P. C. van Doormaal, Ulrike Held, Emanuela Keller, Michael Hugelshofer, Dominik J. Schaer
Summary: This study aims to validate the association between EVD and LD based CSF-Hb and SAH-SBI, and assess the discrimination ability of CSF-Hb. The strength of association will be quantified using a generalized additive model, and receiver operating characteristic analysis will be used for discrimination ability assessment.
Article
Clinical Neurology
Martin Hansel, Klaus Steigmiller, Andreas R. Luft, Catherine Gebhard, Ulrike Held, Susanne Wegener
Summary: Increasing women's economic participation in Switzerland is associated with higher prevalence of non-traditional vascular risk factors in both women and men. This highlights the need for improved vascular risk stratification and implementation of effective preventive measures for neurovascular and cardiovascular diseases.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Rheumatology
Alexandru Garaiman, Klaus Steigmiller, Catherine Gebhard, Carina Mihai, Rucsandra Dobrota, Cosimo Bruni, Marco Matucci-Cerinic, Joerg Henes, Jeska De Vries-Bouwstra, Vanessa Smith, Andrea Doria, Yannick Allanore, Lorenzo Dagna, Branimir Anic, Carlomaurizio Montecucco, Otylia Kowal-Bielecka, Mickael Martin, Yoshiya Tanaka, Anna-Maria Hoffmann-Vold, Ulrike Held, Oliver Distler, Mike Oliver Becker
Summary: The DU-VASC model was developed and validated to assist in decision-making for the management of digital ulcers in patients with systemic sclerosis. The model showed that PI treatment was the most important predictor associated with reduced occurrence of digital ulcers.
Article
Hematology
Stefano Barco, Davide Voci, Ulrike Held, Tim Sebastian, Roland Bingisser, Giuseppe Colucci, Daniel Duerschmied, Andre Frenk, Bernhard Gerber, Andrea Goetschi, Stavros Konstantinides, Francois Mach, Helia Robert-Ebadi, Thomas Rosemann, Noemi R. Simon, Herve Spechbach, David Spirk, Stefan Stortecky, Lukas Vaisnora, Marc Righini, Nils Kucher
Summary: This study aimed to investigate whether thromboprophylaxis with enoxaparin would prevent hospitalization and death in symptomatic COVID-19 outpatients. The results showed that enoxaparin did not reduce the risk of hospitalization and death among these patients.
LANCET HAEMATOLOGY
(2022)
Article
Pediatrics
Celine Steger, Maria Feldmann, Julia Borns, Cornelia Hagmann, Beatrice Latal, Ulrike Held, Andras Jakab, Ruth O'Gorman Tuura, Walter Knirsch
Summary: Reduced white matter NAA/Cho ratios in neonates undergoing cardiac surgery for congenital heart defects may indicate delayed brain maturation. Further research is needed to understand the clinical impact of altered metabolites on brain development and outcome.
PEDIATRIC RESEARCH
(2023)
Article
Surgery
Gabriela Schmid-Mohler, Sonja Beckmann, Patrizia Zala, Laura Huber, Ulrike Held, Thomas Fehr, Rudolf Peter Wuthrich, Heidi Petry, Thomas F. Mueller
Summary: This study aimed to test two models for identifying patients at risk for weight gain and increase in adipose tissue mass in the first year after kidney transplantation. The models included various predictors such as physical activity, smoking cessation, self-reported health status, and baseline body mass index. The results showed that the models have the potential to assess patients' risk, but further testing is needed before implementation in clinical practice.
PROGRESS IN TRANSPLANTATION
(2022)
Article
Medicine, Research & Experimental
Christian D. Fankhauser, Andres Affentranger, Beatrice Cortonesi, Urs Jeker, Markus Gass, Fabrizio Minervini, Georg Jung, Corina Christmann, Christine Brambs, Milo A. Puhan, Ulrike Held
Summary: This study aims to analyze the impact of a preoperative high-intensity smoking cessation intervention on surgical complications and various outcomes in smokers undergoing surgery.
Article
Hematology
Davide Voci, Andrea Gotschi, Ulrike Held, Roland Bingisser, Giuseppe Colucci, Daniel Duerschmied, Riccardo M. Fumagalli, Bernhard Gerber, Barbara Hasse, Dagmar I. Keller, Stavros V. Konstantinides, Francois Mach, Silvana K. Rampini, Marc Righini, Helia Robert-Ebadi, Thomas Rosemann, Stephanie Roth-Zetzsche, Tim Sebastian, Noemi R. Simon, David Spirk, Stefan Stortecky, Lukas Vaisnora, Nils Kucher, Stefano Barco
Summary: The benefits of early thromboprophylaxis in symptomatic COVID-19 outpatients remain unclear. This study presents the 90-day results from the OVID phase III trial, which showed that early thromboprophylaxis with enoxaparin did not improve the course of COVID-19 in terms of hospitalization, death, or resolution of symptoms.
THROMBOSIS RESEARCH
(2023)
Review
Anesthesiology
Gil Kollmann, Maria M. Wertli, Stefan Dudli, Oliver Distler, Florian Brunner
Summary: The aim of this systematic review was to evaluate and analyze the knowledge on bone-related biochemical and histological biomarkers in Complex Regional Pain Syndrome 1 (CRPS 1). The analysis included 7 studies (3 biochemical analyses, 1 animal study, and 3 histological examinations). The limited data revealed potential bone-related biomarkers in CRPS 1, suggesting areas for future research.
EUROPEAN JOURNAL OF PAIN
(2023)
Review
Clinical Neurology
Asha-Naima Ferrante, Barbara K. Keller, Julian S. Flury, Michael A. Harnik, Martin Grosse Holtforth, Maria M. Wertli
Summary: The purpose of this study is to assess the current evidence about the efficacy of communication strategies on the prevention of chronic postsurgical pain (CPSP). The study includes a systematic search of relevant literature and will provide important information for clinicians and researchers.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Medicine, General & Internal
Ilaria Jermini-Gianinazzi, Manuel Blum, Maria Trachsel, Maurizio Alen Trippolini, Nicole Tochtermann, Caroline Rimensberger, Fabian Dominik Liechti, Maria M. Wertli
Summary: The aim of this study was to evaluate the management of acute non-specific low back pain in the emergency departments. The results showed that a substantial proportion of ED physicians did not adhere to current guideline recommendations, with overuse of imaging studies, long-acting opioids, muscle relaxants, and recommendations for activity and work restrictions.
Article
Cardiac & Cardiovascular Systems
Bettina Reich, Sabrina Schwan, Kristina Heye, Thushiha Logeswaran, Andreas Hahn, Andrea Goetschi, Ulrike Held, Kristina Wetterling, Celine Steger, Raimund Kottke, Beatrice Latal, Walter Knirsch
Summary: This study evaluated the long-term effects on brain growth in children with univentricular congenital heart disease. The results showed that these children had impaired neurodevelopmental outcomes and structural brain lesions during school age.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Review
Clinical Neurology
Ilona Stefanos-Yakoub, Kevin Wingeier, Ulrike Held, Beatrice Latal, Elaine Wirrell, Mary Lou Smith, Georgia Ramantani
Summary: In addition to seizure freedom, pediatric epilepsy surgery aims to stabilize and potentially optimize cognitive development. The study conducted a systematic review and meta-analysis to evaluate the changes in intelligence or developmental quotients (IQ/DQ) before and after surgery in children with focal lesional epilepsy. The findings suggest stabilization of intellectual and developmental functioning at long-term follow-up. Cessation of antiseizure medication after achieving seizure freedom may further optimize intellectual and developmental trajectories in affected children.
