Article
Health Care Sciences & Services
Jong-Ho Kim, So-Eun Lee, Hee-Sun Jung, Bo-Seok Shim, Jong-Uk Hou, Young-Suk Kwon
Summary: This study developed an artificial intelligence model that predicts lumbar herniated nucleus pulposus (HNP) using lumbar radiography. The model achieved a certain accuracy through learning and validation, and can assist in the diagnosis of lumbar HNP in clinical practice, although further improvements are needed.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Clinical Neurology
Sang-Min Park, Ho-Jin Lee, Hyun-Jin Park, Jun -Young Choi, Ohsang Kwon, Sanghoon Lee, Ho-Joong Kim, Jin S. Yeom
Summary: This study aimed to compare the clinical efficacy and safety of biportal endoscopic with that of open microscopic discectomy in patients with single-level herniated lumbar discs. The results showed that there was no significant difference in pain and functional recovery between the biportal group and the microscopy group at the 12-month follow-up, indicating the non-inferiority of biportal endoscopic discectomy. The biportal group also had fewer surgery-related adverse events.
Article
Surgery
Azharuddin Azharuddin, Teguh Aryandono, Rahadyan Magetsari, Iwan Dwiprahasto
Summary: This study aimed to identify predictors of conservative management outcomes in patients with lumbar herniated nucleus pulposus. The results showed that patients with dominant radicular pain and reduced motor power of knee extensors were more likely to have poor outcomes. Further studies with larger sample sizes are needed to validate these findings.
ASIAN JOURNAL OF SURGERY
(2022)
Article
Clinical Neurology
Chang Hwa Ham, Youn-Kwan Park, Joo Han Kim, Woo-Keun Kwon, Dong Wook Kim, Hong Joo Moon
Summary: Sagittal spinopelvic alignment (SSPA) parameters are crucial for diagnosing and monitoring the progression of adult spinal deformities (ASDs). Certain clinical symptoms in patients with lumbar spinal stenosis (LSS) and herniated nucleus pulposus (HNP) may distort SSPA and mimic ASD.
Article
Medicine, General & Internal
Joon-Won Seo, Woochul Shin, Bo-Hyung Kim, Man Kyu Choi, Sung Bum Kim, Hyungsuk Kim, Jae-Heung Cho, Won-Seok Chung
Summary: This study aims to analyze and compare the effectiveness, economic feasibility, and safety of using an integrated medical service critical pathway (CP) in treating patients with lumbar herniated nucleus pulposus. The study will collect data and analyze it, with the goal of providing a basis for the development and application of integrated medical services for various diseases, including lumbar herniated nucleus pulposus.
Article
Chemistry, Physical
Yunsong Shi, Kun Wang, Xiaobo Feng, Shuai Li, Hang Liang, Gaocai Li, Wenqiang Li, Wencan Ke, Annan Chen, Xiao Yang, Lei Yang, Chunze Yan, Bin Su, Cao Yang
Summary: The study demonstrates an additive manufactured nucleus pulposus substitute (AMNPS) that can sense mechanical stress in the intervertebral disc and has self-powered capacity. Through in vivo experiments on goats, the potential application of the device for monitoring tissue rehabilitation after discectomy is illustrated.
Article
Medicine, General & Internal
Chi-Hoon Oh, Dong-Eun Shin, Siyeong Yoon, Jongbeom Oh, Younghun Lee, Soonchul Lee
Summary: This study compared the skeletal muscle areas around the lumbar vertebrae between patients with lumbar herniated nucleus pulposus (HNP) and healthy individuals using abdominal pelvic computed tomography (APCT). It found that the ratio of anterior skeletal muscle area was larger in the HNP group. There was also an imbalance in peripheral muscles in HNP male patients.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Sangbong Ko, Jaebum Kwon
Summary: Patients who undergo lumbar discectomy may experience short-term improvement in low back pain (LBP), referred buttock pain (RBP), and lower leg radiating pain (LRP) within the first 3 months postoperatively. However, the improvement in LBP may plateau after 3 months and no further improvement is observed within the first year postoperatively.
Article
Clinical Neurology
Jacob B. Cordover, Glenn S. Fleisig, Jesse A. Raszewskr, Aaron S. Dumone, Andrew M. Cordover
Summary: This study evaluated the return to play rate for young athletes after lumbar microdiscectomy and found a good prognosis. The return to play rate and Pfirrmann grade were not related to gender, sport level, or discectomy level.
WORLD NEUROSURGERY
(2022)
Article
Orthopedics
Wenbo Xu, Bingbing Ran, Jianhui Zhao, Wenqi Luo, Rui Gu
Summary: This study aimed to investigate the incidence and risk factors for failed back surgery syndrome (FBSS) following open posterior lumbar surgery for degenerative lumbar disease (DLD). The results showed that lower preoperative pain level, hypertension, intermittent claudication, HIZ, MCs, and postoperative rehabilitation were risk factors for FBSS.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Clinical Neurology
Andre M. Samuel, Kyle Morse, Francis Lovecchio, Noor Maza, Avani S. Vaishnav, Yoshihiro Katsuura, Sravisht Iyer, Steven J. McAnany, Todd J. Albert, Catherine Himo Gang, Sheeraz A. Qureshi
Summary: A retrospective cohort study on patients undergoing lumbar discectomy revealed that early failures within 30 days postoperatively are rare, but certain subpopulations such as obesity, multilevel surgery, females, and revision discectomies are associated with increased rates of early failure.
GLOBAL SPINE JOURNAL
(2021)
Article
Pharmacology & Pharmacy
Xiaochun Li, Xueqiang Shen, Zhiqiang Wang, Hong Jiang, Zhijia Ma, Pengfei Yu, Zhenhan Yu, Xiang Qian, Jintao Liu
Summary: The differences in gene expression between ruptured and non-ruptured nucleus pulposus tissues of intervertebral discs were examined using gene chip technology. Significant differentially expressed genes were identified, which may be related to intervertebral disc degeneration and self-healing processes.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Developmental Biology
G. E. O. R. G. E. S. O. R. I. N. E. L. DIACONU, C. O. N. S. T. A. N. T. I. N. G. E. O. R. G. E. MIHALACHE, G. E. O. R. G. E. POPESCU, G. E. O. R. G. E. M. I. H. A. I. L. MAN, R. A. Z. V. A. N. G. H. E. O. R. G. H. E. RUSU, C. O. R. N. E. L. I. U. TOADER, C. O. N. S. T. A. N. T. I. N. CIUCUREL, C. R. I. S. T. I. N. A. M. A. R. I. A. N. A. STOCHECI, G. E. O. R. G. E. MITROI, L. U. M. I. N. I. T. A. I. O. N. E. L. A. GEORGESCU
Summary: Lumbar herniated disc is a common cause of lower back pain, often requiring surgical treatment for severe symptoms. Patients with high inflammatory signs may experience longer postoperative recovery and delayed, incomplete motor recovery.
ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY
(2021)
Article
Medicine, General & Internal
Li-Ping Chen, Bin-Song Wen, Heng Xu, Zheng Lu, Lai-Jun Yan, Han Deng, Hong-Bo Fu, Hong-Jie Yuan, Pei-Pei Hu
Summary: The aim of this study was to confirm whether CR-PT is a superior approach to percutaneous transforaminal endoscopic lumbar discectomy compared to AP-PT. The results showed that CR-PT significantly improved puncture accuracy, puncture time, operation time, and pain intensity during puncturing compared to AP-PT.
WORLD JOURNAL OF CLINICAL CASES
(2023)
Article
Immunology
Linbang Wang, Tao He, Jingkun Liu, Jiaojiao Tai, Bing Wang, Lanyue Zhang, Zhengxue Quan
Summary: This study identified key genes involved in immune infiltration in the nucleus pulposus tissue in lumbar disc herniation (LDH) through bioinformatic analysis, revealing significant differences in immune infiltration profiles between the LDH and control groups. The study discussed the crucial roles of regulatory T cells and macrophages in the pathogenesis of LDH, and highlighted the TGF-beta and MAPK signaling pathways as potential diagnostic markers for LDH.
FRONTIERS IN IMMUNOLOGY
(2021)