Article
Orthopedics
Gen Xia, Xueru Li, Yanbing Shang, Bin Fu, Feng Jiang, Huan Liu, Yongdong Qiao
Summary: The study found that in patients with DLSS, the atrophy of muscles in stenotic segments of the spinal canal is significantly greater than in non-stenotic segments, and there is a strong positive correlation between the severity of multifidus atrophy and the severity of spinal stenosis.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Medicine, General & Internal
Ivar M. Austevoll, Erland Hermansen, Morten W. Fagerland, Kjersti Storheim, Jens I. Brox, Tore Solberg, Frode Rekeland, Eric Franssen, Clemens Weber, Helena Brisby, Oliver Grundnes, Knut R. H. Algaard, Tordis Boker, Hasan Banitalebi, Kari Indrekvam, Christian Hellum
Summary: A trial in Norway found that decompression surgery alone was noninferior to decompression with instrumented fusion in terms of the percentage of patients who experienced a 30% reduction in pain and disability scores over a 2-year period, with a noninferiority margin of -15 percentage points.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Neurosciences
Pornpavit Sriphirom, Chaiyaporn Siramanakul, Preewut Chaipanha, Chalit Saepoo
Summary: Interlaminar percutaneous endoscopic decompression is an effective procedure with favorable outcomes in selected patients with stable degenerative spondylolisthesis, improving pain and function in these patients.
Article
Clinical Neurology
Yuto Kobayashi, Koji Tamai, Hiromitsu Toyoda, Hidetomi Terai, Masatoshi Hoshino, Akinobu Suzuki, Shinji Takahashi, Yusuke Hori, Akito Yabu, Hiroaki Nakamura
Summary: Results from a study involving 198 patients with LSS indicate that there was no significant difference in clinical outcomes 5 years after minimally invasive posterior decompression between patients with degenerative spondylolisthesis (DS) and those without DS. Additionally, after carefully excluding patients with segmental instability, DS did not impact the clinical outcomes of minimally invasive decompression surgery.
Article
Surgery
Pin Feng, Qingquan Kong, Bin Zhang, Junlin Liu, Junsong Ma, Yuan Hu
Summary: Percutaneous coaxial large-channel endoscopic lumbar interbody fusion (PCLE-LIF) shows good short-term efficacy and high safety in treating degenerative lumbar spinal stenosis, indicating its potential for broader application.
FRONTIERS IN SURGERY
(2022)
Article
Clinical Neurology
Dimitris Dimitriou, Elin Winkler, Sabrina Weber, Samuel Haupt, Michael Betz, Mazda Farshad
Summary: This study aimed to investigate the treatment failure rate in patients with degenerative lumbar spinal stenosis (DLSS) and introduce a preoperative score that can aid surgical decision-making. Several risk factors, including age, body mass index, smoking status, previous surgery, low back pain, facet joint effusion, and disk degeneration, were associated with an increased risk for treatment failure following decompression for DLSS. A score quantifying amounts of low back pain, facet effusions, and disk degeneration could predict the need for revision surgery in DLSS patients undergoing lumbar decompression without fusion.
Article
Orthopedics
Pengfei Li, Yuexin Tong, Ying Chen, Zhezhe Zhang, Youxin Song
Summary: This study compared the results of PTED and short-segment fusion for treating mild degenerative lumbar scoliosis combined with spinal stenosis in older adults. The PTED group showed significantly shorter operative time, blood loss, postoperative hospital stay, postoperative bed rest, and complication rate compared to the short-segment fusion group.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Cell & Tissue Engineering
Piotr Godek, Beata Szczepanowska-Wolowiec, Dominik Golicki
Summary: This study compares three nonoperative treatment methods for lumbar spinal stenosis, including autologous serum GOLDIC therapy, epidural steroid injections, and manual therapy. The results show that GOLDIC therapy has the highest mean differences and number of cases with minimal important difference among groups for every primary outcome.
REGENERATIVE MEDICINE
(2022)
Article
Orthopedics
Tengbin Shi, Zhi Chen, Dingxiang Hu, Wenwen Li, Zhenyu Wang, Wenge Liu
Summary: This study aimed to investigate the impact of type 2 diabetes mellitus (T2D) on the prognosis of patients with degenerative lumbar spinal stenosis (DLSS) who underwent therapeutic exercises. The results showed that patients with T2D had a lower improvement in leg pain after 6 and 12 weeks of exercise therapy compared to patients without T2D. However, there was no difference between the groups in terms of improvement in low back pain and disability. These findings provide important insights into exercise treatment for patients with DLSS.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Orthopedics
Janan Abbas, Malik Yousef, Natan Peled, Israel Hershkovitz, Kamal Hamoud
Summary: This study aims to detect the essential variables that predict the development of symptomatic degenerative lumbar spinal stenosis (DLSS) using the random forest of machine learning algorithms technique. The results indicate that the anteroposterior diameter of the bony canal at L5 (in males) and L4 (in females) levels have the greatest stimulus for symptomatic DLSS onset.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Neurosciences
Takuya Miura, Toshikazu Ito, Keita Sato, Tatsuya Endo, Masumi Iwabuchi, Osamu Shirado
Summary: This study investigated the impact of dynamic alignment of the spine and pelvis during gait on lumbar function in daily life in patients with lumbar spinal stenosis (LSS). The results showed that weak hip and trunk extensor muscles, a greater angle of pelvic tilt, and less spinal flexion during gait were associated with lower lumbar function in daily life in LSS patients.
Article
Clinical Neurology
Koichi Yoshikane, Katsuhiko Kikuchi, Ken Okazaki
Summary: The study investigated and compared the clinical and radiological outcomes of lumbar endoscopic unilateral laminotomy for bilateral decompression (LE-ULBD) for lumbar spinal stenosis (LSS) patients with and without degenerative spondylolisthesis (DS). The results showed that both groups had favorable clinical outcomes postoperatively, and postoperative segmental instability was not common in patients with DS.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
Tatsuya Yamamoto, Mitsuru Yagi, Satoshi Suzuki, Yohei Takahashi, Satoshi Nori, Osahiko Tsuji, Narihito Nagoshi, Jun Ogawa, Morio Matsumoto, Masaya Nakamura, Kota Watanabe
Summary: In this retrospective study, the outcomes of multilevel posterior decompression surgery for degenerative lumbar spinal stenosis were compared with single-level surgery. The study found that despite the longer surgical time and larger blood loss, multilevel surgery showed similar improvements in patient-reported outcomes and revision rates compared to single-level surgery.
Article
Clinical Neurology
Simran Chhugani, Nivedita Agarwal, Faraz Sheikh, Florina Borca, Aginor Spanoulis, Ian Galea
Summary: The study found that cervical spinal degenerative disease (SDD) is more common in patients with progressive multiple sclerosis (MS), with foraminal stenosis being a significant feature. Therefore, a higher index of suspicion for cervical SDD is needed in progressive MS patients experiencing appropriate neurological symptoms, to guide appropriate treatment or monitoring.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Review
Medicine, General & Internal
Anh Tuan Bui, Giam Minh Trinh, Meng-Huang Wu, Tung Thanh Hoang, Ming-Hsiao Hu, Jwo-Luen Pao
Summary: This systematic review summarized the indications for and outcomes of three main unilateral biportal endoscopic (UBE) approaches for the decompression of degenerative lumbar spinal stenosis (DLSS). The three approaches of UBE surgery were found to be effective and safe for the decompression of various types of DLSS. However, further long-term prospective studies and randomized control trials are needed to explore this new technique.
Article
Medicine, General & Internal
Hoon Choi, Jamie L. Baisden, Narayan Yoganandan
Article
Clinical Neurology
Hoon Choi, Yuvaraj Purushothaman, Jamie Baisden, Narayan Yoganandan
EUROPEAN SPINE JOURNAL
(2020)
Article
Engineering, Biomedical
Narayan Yoganandan, Jason Moore, Nicholas DeVogel, Frank Pintar, Anjishnu Banerjee, Jamie Baisden, Jiang Yue Zhang, Kathryn Loftis, David Barnes
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2020)
Review
Clinical Neurology
D. Scott Kreiner, Paul Matz, Christopher M. Bono, Charles H. Cho, John E. Easa, Gary Ghiselli, Zoher Ghogawala, Charles A. Reitman, Daniel K. Resnick, William C. Watters, Thiru M. Annaswamy, Jamie Baisden, Walter S. Bartynski, Shay Bess, Randall P. Brewer, R. Carter Cassidy, David S. Cheng, Sean D. Christie, Norman B. Chutkan, Bernard Allan Cohen, Simon Dagenais, Dennis E. Enix, Paul Dougherty, S. Raymond Golish, Padma Gulur, Steven W. Hwang, Cumhur Kilincer, Jeffrey A. King, Adam C. Lipson, Anthony J. Lisi, Richard J. Meagher, John E. O'Toole, Paul Park, Murat Pekmezci, Daniel R. Perry, Ravi Prasad, David A. Provenzano, Kris E. Radcliff, Gazanfar Rahmathulla, Tom E. Reinsel, Robert L. Rich, Daniel S. Robbins, Karie A. Rosolowski, Jonathan N. Sembrano, Anil K. Sharma, Alison A. Stout, Christopher K. Taleghani, Ryan A. Tauzell, Terry Trammell, Yakov Vorobeychik, Amy M. Yahiro
Article
Engineering, Biomedical
Yuvaraj Purushothaman, Narayan Yoganandan, Davidson Jebaseelan, Hoon Choi, Jamie Baisden
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2020)
Article
Medicine, General & Internal
Narayan Yoganandan, Jamie L. Baisden, Jobin John, Gurunathan Saravana Kumar, Anjishnu Banerjee, Hoon Choi
Summary: The study found that models with lesser vertebral depth, indicative of female-like spines, experience greater range of motions and pronounced nonphysiological curves during G(+x) loading, potentially leading to greater distraction/stretch of the posterior upper spine complex. The location of the head center of gravity (cg) has a significant influence on the motions of the upper and lower spines and the time of formation of the curve.
Article
Medicine, General & Internal
Alicia Abraczinskas, Ardyn Olszko, Christine Beltran, Jamie L. Baisden, Narayan Yoganandan, James McGhee, Shannon McGovern, Grace Lidl, Kimberly B. Vasquez, Valeta C. Chancey
Summary: The study exposed nonhuman primates (NHPs) to + Gz loading in supine or upright positions to assess the effect of orientation on injuries at accelerations unsafe for human participation. Results showed significant differences in peak sled acceleration (PSA) and injury occurrences between supine and upright orientations, with supine position leading to more central nervous system injuries and upright position leading to more musculoskeletal injuries. Both positions had equal thoracic injuries. The findings emphasize the importance of orientation during acceleration to reduce injury risks in next generation equipment design and testing.
Article
Medicine, General & Internal
Hoon Choi, Vicky Varghese, Jamie Baisden, Diane W. Braza, Anjishnu Banerjee, Narayan Yoganandan
Summary: This study analyzed muscle geometry parameters in 7 young healthy female volunteers using upright magnetic resonance imaging after continuous wear of a standard issued military helmet. The results showed that helmet wear can lead to morphometric alterations in cervical flexor/extensor musculature in females, with significant differences noted at different levels.
Article
Medicine, General & Internal
Hoon Choi, Yuvaraj Purushothaman, Jamie L. Baisden, Deepak Rajasekaran, Davidson Jebaseelan, Narayan Yoganandan
Summary: This study compared the biomechanics of ACDF and CDA surgeries under head supported mass loadings, showing that CDA demonstrates a more physiological response than ACDF, though the exact pattern depends on implant design. The study also found different load-sharing patterns between the two implants, which may impact implant selection based on anatomical and pathological factors at the index and adjacent levels.
Correction
Clinical Neurology
D. Scott Kreiner, Paul Matz, Christopher M. Bono, Charles H. Cho, John E. Easa, Gary Ghiselli, Zoher Ghogawala, Charles A. Reitman, Daniel K. Resnick, William C. Watters III, Thiru M. Annaswamy, Jamie Baisden, Walter S. Bartynski, Shay Bess, Randall P. Brewer, R. Carter Cassidy, David S. Cheng, Sean D. Christie, Norman B. Chutkan, Bernard Allan Cohen, Simon Dagenais, Dennis E. Enix, Paul Dougherty, S. Raymond Golish, Padma Gulur, Steven W. Hwang, Cumhur Kilincer, Jeffrey A. King, Adam C. Lipson, Anthony J. Lisi, Richard J. Meagher, John E. O'Toole, Paul Park, Murat Pekmezci, Daniel R. Perry, Ravi Prasad, David A. Provenzano, Kris E. Radcliff, Gazanfar Rahmathulla, Tom E. Reinsel, Robert L. Rich, Daniel S. Robbins, Karie A. Rosolowski, Jonathan N. Sembrano, Anil K. Sharma, Alison A. Stout, Christopher K. Taleghani, Ryan A. Tauzell, Terry Trammell, Yakov Vorobeychik, Amy M. Yahiro
Article
Clinical Neurology
Charles A. Reitman, Jeffrey M. Hills, Christopher J. Standaert, Christopher M. Bono, Charles A. Mick, Christopher G. Furey, Christopher P. Kauffman, Daniel K. Resnick, David A. Wong, Heidi Prather, James S. Harrop, Jamie Baisden, Jeffrey C. Wang, Jeffrey M. Spivak, Jerome Schofferman, K. Daniel Riew, Mark A. Lorenz, Michael H. Heggeness, Paul A. Anderson, Raj D. Rao, Ray M. Baker, Sanford E. Emery, William C. Watters, William J. Sullivan, William Mitchell, William Tontz Jr, Zoher Ghogawala
Summary: A study was conducted to develop appropriate use criteria for cervical fusion, revealing symptom type as the most strongly correlated modifier with final rating. Myelopathy or radiculopathy were most associated with an Appropriate rating, while axial pain without stenosis was most associated with Rarely Appropriate.
Article
Orthopedics
Yuvaraj Purushothaman, Hoon Choi, Narayan Yoganandan, Davidson Jebaseelan, Jamie Baisden, Shekar Kurpad
Summary: This study analyzed and compared the biomechanical behavior of four artificial cervical disks using validated finite element models, showing that the Secure-C and Mobi-C prostheses could reduce intradiscal pressures at adjacent levels. The findings provide guidance for clinical decision-making in choosing CDA procedures.
ASIAN SPINE JOURNAL
(2021)
Article
Engineering, Biomedical
Narayan Yoganandan, Yuvaraj Purushothaman, Hoon Choi, Davidson Jebaseelan, Jamie Baisden
Summary: The study found that removal of the uncinate process during cervical disc arthroplasty can increase motion at the index level while decreasing motion at adjacent levels. Additionally, removal of the uncinate process also reduces disc pressure and facet loads at adjacent segments.
CLINICAL BIOMECHANICS
(2021)
Article
Engineering, Biomedical
Sagar Umale, Narayan Yoganandan, Jamie L. Baisden, Hoon Choi, Shekar N. Kurpad
Summary: This study investigated the biomechanical effects of various lumbar interbody fusion techniques on the spine using a validated finite-element model. The results showed that bilateral posterior instrumentations (TLIF, PLIF, and CLIF/360) resulted in the greatest reduction in lumbar spine range of motion, with forces transmitted through the vertebrae and disc pressures increasing proportionally to the range of motion. The study provides valuable information for surgeons to make informed decisions when selecting fusion procedures based on biomechanical effects.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Otorhinolaryngology
Narayan Yoganandan, Hoon Choi, Yuvaraj Purushothaman, Davidson Jebaseelan, Jamie Baisden, Shekar Kurpad
JOURNAL OF CRANIOVERTEBRAL JUNCTION AND SPINE
(2020)