Article
Biotechnology & Applied Microbiology
Seyed Javad Mousavi, Andrew C. Lynch, Brett T. Allaire, Andrew P. White, Dennis E. Anderson
Summary: The study found that patients with symptomatic lumbar spinal stenosis exhibit slight changes in spine posture and pelvic tilt during standing and walking, but these changes are not significantly affected by symptoms. However, there was an average 7% increase in lumbar spine loading during symptomatic walking compared to asymptomatic walking. This suggests that provocation of symptoms in patients with lumbar spinal stenosis does not greatly alter their normal gait kinematics.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Clinical Neurology
Suzanne McIlroy, Feroz Jadhakhan, David Bell, Alison Rushton
Summary: This study found that older age, obesity, greater pre-operative pain and disability, and lower quality of life are associated with an increased risk of poor walking ability post-surgery for lumbar spinal stenosis. On the other hand, greater pre-operative walking distance and higher education were associated with a decreased risk of poor walking ability post-surgery. Patients should be informed of their risk factors and may benefit from rehabilitation to improve their walking and surgical outcomes.
EUROPEAN SPINE JOURNAL
(2021)
Review
Clinical Neurology
Marieve Houle, Jean-Daniel Bonneau, Andree-Anne Marchand, Martin Descarreaux
Summary: This study included 24 studies and found that walking capacity was significantly correlated with factors such as pain, disability, and gait pattern characteristics. However, many associations between physical or psychological factors and walking capacity were conflicting, even more so when specifically correlated with walking capacity.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Malin E. A. K. Gustafsson, Berit Schiottz-Christensen, Niels Wedderkopp, Jan C. Brond
Summary: This study aimed to develop and test a method for step detection using accelerometer data in patients with lumbar spinal stenosis (LSS). The results showed that the ankle-worn accelerometer provided the most accurate step count, but falsely registered steps during nonwalking activities. The developed method shows potential as a measure of walking activity, but further development and testing are needed.
Article
Multidisciplinary Sciences
Ryan J. Downey, Natalie Richer, Rohan Gupta, Chang Liu, Erika M. Pliner, Arkaprava Roy, Jungyun Hwang, David J. Clark, Chris J. Hass, Todd M. Manini, Rachael D. Seidler, Daniel P. Ferris
Summary: This study investigated the effects of altering terrain unevenness on gait kinematics, and found that increasing terrain unevenness led to greater stride-to-stride variability and reduced perceived stability in participants.
Article
Geriatrics & Gerontology
Suzanne McIlroy, Edward Walsh, Christina Sothinathan, Elizabeth Stovold, Daniel Norwitz, Sam Norton, John Weinman, Lindsay Bearne
Summary: The study found a strong positive correlation between preoperative walking capacity and postoperative walking capacity. However, spondylolisthesis and the severity of stenosis were not associated with postoperative walking capacity. Further research is needed on mutable prognostic factors to optimize surgical outcomes.
Article
Rehabilitation
Chiara Masi, Gaelle Couraud, Camille Daste, Jennifer Jouffriault, Serge Poiraudeau, Marie-Martine Lefevre-Colau, Francois Rannou, Christelle Nguyen
Summary: This study aimed to develop a new patient-reported outcome measure, CSS-19, to assess activities and participation in people with LSS. The instrument showed good content and construct validity, highlighting the importance of prioritizing patients' perspectives in the development process.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2021)
Article
Medicine, General & Internal
Minsoo Kim, Soyeon Cho, Yeonji Noh, Daehun Goh, Hee-Jeong Son, Jin Huh, Seong-Sik Kang, Byeongmun Hwang
Summary: This study examined the effects of epidural steroid injection (ESI) on pain scores and walking distance in patients with lumbar central spinal stenosis. The results showed that moderate stenosis patients had decreased pain scores and increased walking distance two weeks after the ESI, while severe stenosis patients had decreased pain scores with no significant change in walking distance. Patients with moderate stenosis achieved better outcomes than those with severe stenosis.
Article
Orthopedics
Takashi Wada, Shinji Tanishima, Yuki Kitsuda, Mari Osaki, Hideki Nagashima, Hisashi Noma, Hiroshi Hagino
Summary: The results of this study suggest that changes in postoperative pain catastrophizing after lumbar spine surgery are associated with walking speed. Thus, walking speed is an important assessment for the management of pain catastrophizing and associated pain and disability in patients after lumbar spine surgery.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Medicine, General & Internal
Minsoo Kim, Jiwon Bak, Daehun Goh, Jangho Bae, Kiyoung Shin, Hee-Jeong Son, Jin Huh, Seong-Sik Kang, Byeongmun Hwang
Summary: This study evaluated the effect of TFESI on pain scores and walking distance in patients with lumbar foraminal spinal stenosis. It found that TFESI significantly reduced pain scores and increased walking distance in patients after 4 weeks of treatment. However, patients with moderate disease severity had better pain relief outcomes and satisfaction compared to those with severe disease severity.
Article
Anesthesiology
Ahmed J. Awad, Braden Jex, Gwynne Kirchen, Stacy Peterson, Sarah A. Endrizzi, Peter A. Pahapill
Summary: The study demonstrates the favorable long-term efficacy of SCS in treating neurogenic claudication, especially for patients without prior surgical decompression. Despite its retrospective nature and single-center design, the results suggest that SCS can be considered as part of conservative treatment to help patients alleviate spine-related pain.
Article
Orthopedics
Gen Xia, Xueru Li, Yanbing Shang, Bin Fu, Feng Jiang, Huan Liu, Yongdong Qiao
Summary: The study found that in patients with DLSS, the atrophy of muscles in stenotic segments of the spinal canal is significantly greater than in non-stenotic segments, and there is a strong positive correlation between the severity of multifidus atrophy and the severity of spinal stenosis.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Anesthesiology
Sung Hyun Lee, Sung-Ha Hwang, Young-Kwan Moon, Hyun Min Bae, Dong Eon Moon
Summary: This retrospective study evaluated the clinical outcomes and safety of TFFP in 112 patients, showing that TFFP using the Foramoon device was effective in improving pain scores, ODI, and walking distance without serious adverse events.
Article
Medicine, Research & Experimental
Marieve Houle, Charles Tetreau, Claude-Edouard Chatillon, Andree-Anne Marchand, Martin Descarreaux
Summary: The study aims to evaluate the effectiveness of a 6-week specific rehabilitation program combining education and exercises on walking capacity in patients with lumbar spinal stenosis causing neurogenic claudication. The study will also provide new information about the impact of neurogenic claudication on gait pattern, potentially improving the evaluation and management of lumbar spinal stenosis.
Article
Neurosciences
Corina Nuesch, Filippo Mandelli, Philip Przybilla, Stefan Scharen, Annegret Mundermann, Cordula Netzer
Summary: The study found differences in gait and muscle activation patterns between patients with sLSS and healthy controls. These differences can be measured using wearable sensors and provide additional functional outcomes reflecting the functional status of patients.
Article
Rehabilitation
Robert Froud, Pal Andre Amundsen, Serena Bartys, Michele Battie, Kim Burton, Nadine E. Foster, Tone Langjordet Johnsen, Tamar Pincus, Michiel F. Reneman, Rob J. E. M. Smeets, Vigdis Sveinsdottir, Gwenllian Wynne-Jones, Martin Underwood
Summary: An expert panel identified that the most important opportunities and challenges around adapting supported employment interventions for people with chronic low back pain include facilitating integration between systems and institutions, optimizing research outputs for informing policy needs, and discussing funding mechanisms for research and interventions.
DISABILITY AND REHABILITATION
(2021)
Article
Orthopedics
Z. Y. Feng, X. J. Hu, Q. Q. Zheng, M. C. Battie, Z. Chen, Y. Wang
Summary: The study revealed that cartilaginous endplate avulsion following lumbar disc herniation surgery is associated with residual back and leg pain, Modic changes, and endplate defects. Histologically, avulsed cartilaginous endplates show multiple defects, inflammatory responses, and nucleus invasion, potentially linked to NLRP3 inflammasome related inflammations.
OSTEOARTHRITIS AND CARTILAGE
(2021)
Review
Anesthesiology
Adam M. R. Groh, Dale E. Fournier, Michele C. Battie, Cheryle A. Seguin
Summary: This study provides a comprehensive systematic overview of the topography, morphology, and immunoreactivity of neural elements within the intervertebral disc (IVD) in humans. Nerves mainly localize in the outer layers of the annulus fibrosus, with neural ingrowth into the inner layers only in degenerative and disease states. Despite the clear pattern of innervation within the IVD, the specific topographic arrangement and function of neural elements in the context of back pain remains unclear.
Article
Orthopedics
R. Sun, C. Tomkins-Lane, A. Muaremi, A. Kuwabara, M. Smuck
Summary: The study investigates the relationship between physical performance and capacity in KOA patients, deriving accelerometry measured thresholds associated with gait speed decline that may guide disease-specific physical activity guidelines. The most impactful predicting feature for gait decline is low minutes in moderate-vigorous activity. Using a novel machine learning interpretation algorithm, feature thresholds were established to increase the probability of gait decline, providing meaningful information for establishing specific physical activity guidelines for KOA patients.
OSTEOARTHRITIS AND CARTILAGE
(2021)
Review
Clinical Neurology
Aliyu Lawan, Jackson Crites Videman, Michele C. Battie
Summary: The study reveals a significant association between endplate structural defects and back pain, especially for erosion, sclerosis, and Schmorl's nodes. Research on specific endplate defect phenotypes and back pain case definitions will be crucial in clarifying the extent of these associations.
EUROPEAN SPINE JOURNAL
(2021)
Review
Clinical Neurology
Paul W. Hodges, Jeannie F. Bailey, Maryse Fortin, Michele C. Battie
Summary: Paraspinal muscle imaging is important for understanding spinal health, but inconsistencies in studies are often due to factors such as neglecting underlying mechanisms of muscle changes, lack of control for confounding factors, and variations in imaging modalities and measurement protocols. Standardized measures and consideration of potential confounding factors are essential for advancing knowledge in this field.
EUROPEAN SPINE JOURNAL
(2021)
Article
Multidisciplinary Sciences
Yiming Xiao, Maryse Fortin, Joshua Ahn, Hassan Rivaz, Terry M. Peters, Michele C. Battie
Summary: The study presents the first investigation using statistical shape analysis technique to reveal disease-related paraspinal muscle asymmetry, offering new possibilities to improve understanding of low back pain and various lumbar pathologies.
SCIENTIFIC REPORTS
(2021)
Article
Rehabilitation
Mark J. Hancock, Chris G. Maher, Jeffrey G. Jarvik, Michele C. Battie, James M. Elliott, Tue S. Jensen, John Panagopoulos, Hazel Jenkins, Margery C. Pardey, Jeffery McIntosh, John Magnussen
Summary: The study investigated the interrater reliability of subjective radiologist reporting of temporal changes in lumbar MRI findings and found that the reliability was low with relatively few false positive reports.
Article
Clinical Neurology
Vahid Abdollah, Eric C. Parent, Samin Dolatabadi, Erica Marr, Keith Wachowicz, Michele Battie
Summary: Advances in texture analysis and machine learning provide new opportunities for applying imaging to intervertebral disc biomechanics. This study used these techniques to investigate lumbar disc response to loading, finding significant differences in the nucleus and posterior annulus at the L4-5 level between compression and traction. MRI textural features show potential in identifying how discs respond to loading, with the nucleus and posterior annulus being most sensitive.
EUROPEAN SPINE JOURNAL
(2022)
Review
Orthopedics
Luciana Gazzi Macedo, Kenneth S. Noguchi, Lisandra A. de Oliveira, Nora Bakaa, Stephanie Di Pelino, Michele C. Battie
Summary: The objective of this systematic review was to evaluate the association of exposure to whole-body vibration (WBV) with spine degeneration on imaging. The results suggest that there is currently not enough evidence to support the claim that motorized vehicle and WBV exposure accelerates degeneration and causes structural damage to the spine.
JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION
(2022)
Article
Orthopedics
Xuan Lu, Zhiwei Zhu, Jianjiang Pan, Zhiyun Feng, Xiaoqiang Lv, Michele C. Battie, Yue Wang
Summary: Traumatic vertebral fractures are associated with accelerated adjacent disc degeneration, further promoted by concomitant endplate fractures. Endplate fractures are associated with progression of segmental kyphosis.
SKELETAL RADIOLOGY
(2022)
Article
Orthopedics
Christine Comer, Carlo Ammendolia, Michele C. Battie, Andre Bussieres, Jeremy Fairbank, Andrew Haig, Markus Melloh, Anthony Redmond, Michael J. Schneider, Christopher J. Standaert, Christy Tomkins-Lane, Esther Williamson, Arnold Y. L. Wong
Summary: This study developed a treatment algorithm for lumbar spinal stenosis (LSS) based on international multi-professional expert consensus. The algorithm provides different pathway options based on clinical indications, aiming to improve patient outcomes and healthcare resource utilization.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Clinical Neurology
Clermont E. Dionne, Michel Rossignol, Richard A. Deyo, Bart Koes, Mark Schoene, Michele Battie
Summary: This paper discusses the current state and future direction of research in the field of back and neck pain. It highlights the progress made in improving the management of back pain in the past 25 years and identifies key challenges such as integrating physical and psychological interventions, understanding the biological mechanisms, and addressing back pain in low-income countries.
Meeting Abstract
Biochemistry & Molecular Biology
James Faul, Michele Battie
Article
Medicine, Research & Experimental
Luciana G. Macedo, Julie Richardson, Michele C. Battie, Mark Hancock, Matthew Kwan, Genevieve Hladysh, Linda Zhuo
Summary: The study aimed to test the feasibility of the Back to Living Well program for preventing recurrence or flare-ups of LBP. Results demonstrate that the program is feasible in terms of recruitment, low attrition, and patient satisfaction.
PILOT AND FEASIBILITY STUDIES
(2021)
