Review
Clinical Neurology
Yongjae Cho, Dae Jean Jo, Seung-Jae Hyun, Jin Hoon Park, Na Rae Yang
Summary: Over the past 20 years, sagittal alignment and balance of the spine have gained significant importance in spine surgery. Recent studies highlight the crucial role of sagittal balance and alignment in health-related quality of life. Understanding normal and abnormal sagittal alignment is essential for diagnosing and treating adult spinal deformity (ASD), and this article discusses the classification of ASD, essential parameters for diagnosing spinal deformity, compensatory actions for maintaining sagittal balance, and the relationship between sagittal alignment and clinical symptoms. Additionally, it explores the newly introduced Global Alignment and Proportion scores. The Korean Spinal Deformity Society is publishing a series of review articles on spinal deformities to provide better understanding for spine surgeons.
Article
Clinical Neurology
Justin S. Smith, Michael P. Kelly, Thomas J. Buell, David Ben-Israel, Bassel Diebo, Justin K. Scheer, Breton Line, Virginie Lafage, Renaud Lafage, Eric Klineberg, Han Jo Kim, Peter Passias, Jeffrey L. Gum, Khal Kebaish, Jeffrey P. Mullin, Robert Eastlack, Alan Daniels, Alex Soroceanu, Gregory Mundis, Richard Hostin, Themistocles S. Protopsaltis, D. Kojo Hamilton, Munish Gupta, Stephen J. Lewis, Frank J. Schwab, Lawrence G. Lenke, Christopher I. Shaffrey, Douglas Burton, Christopher P. Ames, Shay Bess
Summary: Compared with ATLD patients, ACD patients had worse baseline characteristics on all measures assessed (comorbidities/disability/frailty). These differences may help account for greater risk of complications and all-cause mortality previously observed in ACD patients and facilitate strategies for better preoperative optimization.
GLOBAL SPINE JOURNAL
(2023)
Article
Psychology, Multidisciplinary
Timothy C. Bates, Gilles E. Gignac
Summary: Test motivation has a negligible influence on intelligence test performance in neurotypical adults, and individual differences in motivation may be attributed to differences in ability and outcome expectations.
Article
Clinical Neurology
J. Naresh-Babu, Kenny Yat Hong Kwan, Yabin Wu, Caglar Yilgor, Ahmet Alanay, Kenneth M. C. Cheung, David W. Polly, Jong-Beom Park, Manabu Ito, Lawrence G. Lenke, Miranda L. van Hooff, Marinus de Kleuver
Summary: The study aims to collect information on the factors that drive decision-making by developing a patient profile for adult spinal deformity (ASD). The patient profile was found to have excellent content validity and usability. Physicians are encouraged to assess ASD patients holistically using this profile, rather than relying solely on radiographic findings.
GLOBAL SPINE JOURNAL
(2023)
Article
Medicine, General & Internal
Alice Baroncini, Filippo Migliorini, Francesco Langella, Paolo Barletta, Per Trobisch, Riccardo Cecchinato, Marco Damilano, Emanuele Quarto, Claudio Lamartina, Pedro Berjano
Summary: This study aimed to analyze the association between demographic or perioperative factors and 2-year clinical outcomes after long spine fusion for adult deformity. The results showed that ODI and VAS at 2 years were mainly correlated with preoperative ODI and pain level.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Rehabilitation
Kati Kyrola, Arja H. Hakkinen, Jan Ylinen, Jussi P. Repo
Summary: The study confirmed the validity of the SRS-30 questionnaire in assessing health-related quality of life in adult patients with degenerative spinal disorders, showing consistent performance across different pain subgroups, indicating good convergent validity compared to other HRQoL instruments. The scale demonstrated good coverage and targeting for all three subgroup, independently of age, gender, or deformity severity.
DISABILITY AND REHABILITATION
(2021)
Article
Clinical Neurology
Won Hyung A. Ryu, Andrew Platt, John E. O'Toole, Ricardo Fontes, Richard G. Fessler
Summary: The study found that most patients undergoing surgery for adult spinal deformity (ASD) expected successful surgery and significant reduction in back and leg pain. Patients who met their expectations for leg pain reduction had significantly higher satisfaction scores than those who did not. Preoperative expectations were positively correlated with improvements in pain and mental health scores.
WORLD NEUROSURGERY
(2021)
Article
Multidisciplinary Sciences
Mutsuya Shimizu, Tetsuya Kobayashi, Hisashi Chiba, Issei Senoo, Kozaburo Mizutani, Kengo Sasai
Summary: In this study, 124 females with spondylolisthesis were divided into three groups (A group: anterolisthesis; P group: retrolisthesis; and AP group: antero-retrolisthesis). The results showed that participants in the P group had lower pelvic incidence (PI), sacral slope (SS), and lumbar lordosis-thoracic kyphosis (LL-TK) compared to the A and AP groups. The P and AP groups also had higher thoracic kyphosis (TK) and lower physical function and quality of life scores.
SCIENTIFIC REPORTS
(2023)
Article
Clinical Neurology
Ryan C. Hofler, Jordan Iordanou, Russ P. Nockels
Summary: This study investigated the use of intraoperative anteroposterior long cassette radiographs (APLCRs) to guide kickstand rod application in adult spinal deformity correction. The results showed that APLCRs can help guide the use of a kickstand rod, and patients with a larger fractional lumbar curve may benefit more from the use of a kickstand rod.
WORLD NEUROSURGERY
(2022)
Article
Nutrition & Dietetics
Katrin A. Boeckmann, Axel R. Franz, Michaela Minarski, Anna Shunova, Christian A. Maiwald, Julian Schwarz, Maximilian Gross, Christian F. Poets, Wolfgang Bernhard
Summary: The study compared four different choline supplements and their impact on plasma concentration and kinetics of choline, betaine and TMAO. Results showed that all supplements rapidly increased choline and betaine levels to a similar extent, with egg-PC having the latest peak. Egg-PC may be the best choice for choline supplementation in adults due to potentially lower TMAO production.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Medicine, General & Internal
Hui Dong, Janneke Koerts, Gerdina H. M. Pijnenborg, Norbert Scherbaum, Bernhard W. Mueller, Anselm B. M. Fuermaier
Summary: This study investigates the base rates of noncredible performance in clinical evaluations of adult ADHD and the impact of various factors on cognitive underperformance and symptom overreporting. The study finds that noncredible performance is relatively common throughout the assessment process, with tests for attention and concentration being the most suitable and sensitive for detecting underperformance. Cognitive underperformance is distinct from symptom overreporting. The findings emphasize the importance of conducting multiple validity measures, administering tests at different time points, and improving the calculation of positive and negative predictive values for noncredible performance.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Mitsuru Yagi, Takehiro Michikawa, Satoshi Suzuki, Eijiro Okada, Satoshi Nori, Osahiko Tsuji, Narihito Nagoshi, Takashi Asazuma, Naobumi Hosogane, Nobuyuki Fujita, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
Summary: The study retrospectively reviewed 159 surgically treated consecutive adult symptomatic lumbar deformity patients and identified frailty, baseline mental-health, function, GAP score, and SAE as independent risks for poor clinical outcome; only 17% of poor-risk patients showed improvement to an SRS22 total score >4.0 at 2 years.
Article
Clinical Neurology
Scott L. Zuckerman, Meghan Cerpa, Lawrence G. Lenke, Christopher Shaffrey, Leah Y. Carreon, Kenneth M. C. Cheung, Michael P. Kelly, Michael G. Fehlings, Christopher P. Ames, Oheneba Boachie-Adjei, Mark B. Dekutoski, Khaled M. Kabeaish, Stephen J. Lewis, Yukihiro Matsuyama, Ferran Pellise, Yong Qiu, Frank J. Schwab, Justin S. Smith
Summary: After complex ASD surgery, significant improvements in patient-reported outcomes (PROs) were observed at the 5-year follow-up. However, no significant changes in PROs were seen during the 2 to 5-year postoperative period. Patients with major surgery-related complications showed similar PROs and proportion of patients achieving MCID compared to those without such complications.
GLOBAL SPINE JOURNAL
(2022)
Review
Medicine, General & Internal
Chiara Polichetti, Maria Ilaria Borruto, Francesco Lauriero, Silvio Caravelli, Massimiliano Mosca, Giulio Maccauro, Tommaso Greco, Carlo Perisano
Summary: Adult acquired flatfoot deformity (AAFD) is a disorder caused by repetitive overloading, resulting in progressive posterior tibialis tendon insufficiency. Imaging plays a key role in diagnosis and management, with weight-bearing radiography and MRI being useful for confirmation and evaluation. Ultrasonography and CT are additional tools to evaluate soft-tissue structures and hindfoot abnormalities. More advanced imaging techniques, such as multiplanar weight-bearing imaging, have potential but are not yet standardized.
Article
Clinical Neurology
James P. Wondra II, Michael P. Kelly, Jacob Greenberg, Elizabeth L. Yanik, Christopher P. Ames, Ferran Pellise, Alba Vila-Casademunt, Justin S. Smith, Shay Bess, Christopher I. Shaffrey, Lawrence G. Lenke, Miquel Serra-Burriel, Keith H. Bridwell
Summary: This post hoc analysis examined the performance of machine learning models in predicting outcomes for adult symptomatic lumbar scoliosis patients. The results showed that the models performed better than chance in predicting major complications, reoperations, and hospital readmissions.