Article
Chemistry, Analytical
Maohua Lin, Rudy Paul, Xinqin Liao, James Doulgeris, Emma Lilly Menzer, Utpal Kanti Dhar, Chi-Tay Tsai, Frank D. Vrionis
Summary: This study developed a new method to evaluate the pressure between the vertebrae and implanted devices using an embedded sensor array. By using a robotic arm to simulate natural spine motions and a finite element mathematical model, the results showed that the sensor is effective in identifying static pressure. This study suggests that the sensor array has the potential to reduce trial and error with implants in surgical procedures.
Article
Computer Science, Interdisciplinary Applications
Guangming Xu, Ziyang Liang, Tengfei Tian, Qingnan Meng, Komera Musoni Bertin, Fuhao Mo
Summary: In this study, a complete finite element spinal model was established to analyze the effects of musculoskeletal imbalance, specifically concerning sarcopenia. The results showed that sarcopenia primarily led to increased stress or strain in the L4-L5 intervertebral disc, L1 vertebrae, and L3-S1 joint capsule, thereby increasing the risk of spinal injuries.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Oncology
Junsong Yang, Qingda Li, Peng Liu, Liang Yan, Tuanjiang Liu, Jijun Liu, Qinpeng Zhao, Baorong He, He Zhao, Bing Qian, Yuanting Zhao, Dingjun Hao
Summary: In this study, a three-dimensional finite element model was used to evaluate the mechanical stability of different severity levels of lateral mass injuries. The results showed that type 4 lateral mass injuries had higher stress and range of motion under exercise loads, significantly affecting the biomechanical stability after anterior fixation.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2022)
Article
Biotechnology & Applied Microbiology
Wei Wei, Xianping Du, Na Li, Yunjie Liao, Lifeng Li, Song Peng, Wei Wang, Pengfei Rong, Yin Liu
Summary: Changes in T1 tilt may alter biomechanical loadings of cervical spine segments, especially of the adjacent segments after ACF surgery. Extension may be more susceptible to T1 tilt changes.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Medicine, General & Internal
Jie Li, Kaifeng Gan, Binhui Chen, Yilei Chen, Jinjiong Hong, Dikai Bei, Tengdi Fan, Minzhe Zheng, Liujun Zhao, Fengdong Zhao
Summary: Based on finite element analysis, this study suggests that anterior cervical transpedicular screws (ACTPS) may be a more reasonable choice than anterior cervical screw plate system (ACSPS) for reconstruction after a 2-level corpectomy in the subaxial cervical spine. ACTPS showed better reduction in range of motion and lower risk of internal fixator failure compared to ACSPS.
Article
Biotechnology & Applied Microbiology
L. Pachocki, K. Daszkiewicz, P. Luczkiewicz, W. Witkowski
Summary: This study utilized finite element method to conduct numerical simulations, finding that lumbar spine fractures could occur during vehicle collisions with concrete road safety barriers, primarily affecting the L1-L3 lumbar spine section. The fractures were caused by a combination of axial forces and flexion bending moments.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Clinical Neurology
Norihiro Nishida, Sudharshan Tripathi, Muzammil Mumtaz, Amey Kelkar, Yogesh Kumaran, Takashi Sakai, Vijay K. Goel
Summary: This biomechanical study investigated the risk factors of soft tissue cervical spine injury (CSI) and found that the intervertebral disk (ID) is the most important component in stabilizing the cervical spine.
WORLD NEUROSURGERY
(2022)
Article
Computer Science, Interdisciplinary Applications
Ziyang Liang, Fuhao Mo, Zhefen Zheng, Yuandong Li, Ye Tian, Xiaobing Jiang, Tang Liu
Summary: This study investigates the influences of neural reflex control on neck biomechanical responses using a new finite element head-neck model. The results show that the model with neural reflex control presents rational head-neck kinematics and tissue injury risk. The muscle activation forces caused by neural reflex control change the tissue load concentration locations and stress/strain levels during the loading process. The study demonstrates the importance of considering neural reflex in finite element analysis of a head-neck system and quantifies the protective effect of muscle activation on the neck.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Afonso J. C. Silva, Ricardo J. Alves de Sousa, Fabio A. O. Fernandes, Mariusz Ptak, Marco P. L. Parente
Summary: The main objective of this study is to better understand the mechanics of the neck by creating a finite element model that accurately represents most components of the human cervical spine. The model has been validated and shows agreement with experimental data.
APPLIED SCIENCES-BASEL
(2022)
Article
Orthopedics
Jun Sun, Qiuan Wang, Dazhao Cai, Wenxiang Gu, Yiming Ma, Yang Sun, Yangyang Wei, Feng Yuan
Summary: The study compared the biomechanical behavior of cervical spines after implanting ZK60 and titanium fusion cages. Results showed that ZK60 increased stress stimulation to bone grafts compared to titanium cages due to reduced stress shielding effects. Additionally, a lattice-optimized porous cage design exhibited improved biomechanical properties.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Clinical Neurology
Norihiro Nishida, Sudharshan Tripathi, Muzammil Mumtaz, Amey Kelkar, Yogesh Kumaran, Takashi Sakai, Vijay K. Goel
Summary: This study used finite element analysis to investigate the effects of surgical procedures for cervical spine injury. The results showed that the combined anterior-posterior fixation (APF) model preserved cervical stabilization, and the posterior-only fixation (PF) model had an advantage over the anterior-only fixation (AF) model in terms of range of motion, except for flexion. Understanding biomechanics provides useful information for clinicians.
WORLD NEUROSURGERY
(2023)
Article
Biotechnology & Applied Microbiology
Yang Wang, Yang Liu, Aobo Zhang, Qing Han, Jianhang Jiao, Hao Chen, Xuqiang Gong, Wangwang Luo, Jing Yue, Xue Zhao, Jincheng Wang, Minfei Wu
Summary: This study aimed to design a novel individualized zero-profile (NIZP) cage and evaluate its potential to enhance the biomechanical performance between the instrument and the cervical spine. The results showed that the NIZP cage had better biomechanical performance compared to the cage and plate constructs (CPCs), with a lower stress distribution on the cage and a more moderate effect on the adjacent segmental discs. This study could serve as a valuable reference for the development of personalized instruments.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Clinical Neurology
Balaji Harinathan, Davidson Jebaseelan, Narayan Yoganandan, Aditya Vedantam
Summary: This study used a three-dimensional finite element model of the human head-neck complex to simulate different degrees of cervical stenosis and investigate the risk of spinal cord injury during a severe impact. The results showed that as the degree of stenosis and impact velocity increased, the stress and strain on the spinal cord also increased. For a 6 mm cervical stenosis, the stress and strain on the spinal cord exceeded the threshold for spinal cord injury at a velocity of 2.6 m/s.
Article
Engineering, Civil
Hanfeng Yin, Lizhou Zhang, Zhipeng Liu, Wei Fan, Xin Wu, Guilin Wen
Summary: A new separate W-beam guardrail named SWG was developed and compared with the traditional W-beam guardrail (TWG) using finite element simulation. The collision results show that the new W-beam guardrail performs better than TWG, reducing occupant injury and correcting the direction of the out-of-control vehicle. The strength and installation of the bolts and the working width significantly affect the safety performance of the new guardrail.
ENGINEERING STRUCTURES
(2023)
Article
Clinical Neurology
Maohua Lin, Stephen Z. Shapiro, James Doulgeris, Erik D. Engeberg, Chi-Tay Tsai, Frank D. Vrionis
Summary: This study examined the impact of cage-screws on the biomechanical characteristics of the human spine, implanted cage, and associated hardware by comparing micromotion and subsidence. The combination of cage-screws and anterior plating has the potential to reduce micromotion and subsidence in two or more level ACDFs, decreasing the risk of pseudarthrosis and the need for revision surgeries.
Article
Biophysics
Eunjoo Hwang, Jingwen Hu, Matthew P. Reed
JOURNAL OF BIOMECHANICS
(2020)
Article
Engineering, Biomedical
Ming Shen, Shengxiong Liu, Xin Jin, Haojie Mao, Feng Zhu, Tal Saif, Runzhou Zhou, Haonan Fan, Paul C. Begeman, Clifford C. Chou, King H. Yang
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2020)
Article
Public, Environmental & Occupational Health
Jingwen Hu, Nichole Orton, Miriam A. Manary, Kyle Boyle, Lawrence W. Schneider
TRAFFIC INJURY PREVENTION
(2020)
Article
Biophysics
Xianping Du, Binhui Jiang, Guanjun Zhang, Clifford C. Chou, Zhonghao Bai
Summary: This study investigated the bending fracture behaviors of long bones using porcine specimens in three-point bending tests under a rigid indenter. Findings included the deflection of fracture path due to indentation-induced mesoscale crack-opening, establishment of a bone fracture moment correction, force fluctuation caused by plastic indentation, and correlation between bone failure moment and inertial moment of the bone cross section. Additionally, subject-specific simulations demonstrated compression fractures under lower forces induced by indentation, with element erosion on the indenter-contacted area as a potential solution.
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
(2021)
Article
Public, Environmental & Occupational Health
Wenrui Gao, Zhonghao Bai, Huan Li, Yu Liu, Clifford C. Chou, Binhui Jiang
TRAFFIC INJURY PREVENTION
(2020)
Article
Public, Environmental & Occupational Health
Kyle Boyle, Abeselom Fanta, Matthew P. Reed, Kurt Fischer, Alex Smith, Angelo Adler, Jingwen Hu
Summary: This study investigates the impact of occupant size and shape, posture, and restraint design on injury risk in high-speed frontal crashes. Improved restraint designs were found to effectively reduce injury risks, especially for occupants of different body types and genders.
TRAFFIC INJURY PREVENTION
(2020)
Article
Public, Environmental & Occupational Health
Monica L. H. Jones, Sheila M. Ebert, Oliver Varban, Jingwen Hu, Matthew P. Reed, Para Weerappuli, Srinivasan Sundarajan, Saeed Barbat
Summary: The study found that higher levels of obesity result in the seat belt being positioned further away from the skeleton, potentially increasing injury risk during a crash. Sex differences were found to have an important effect on seat belt fit, even after accounting for BMI and stature. The study concluded that further research is needed to improve seat belt fit for obese individuals, including addressing sex differences in belt routing.
TRAFFIC INJURY PREVENTION
(2021)
Article
Ergonomics
Wenrui Gao, Zhonghao Bai, Feng Zhu, Clifford C. Chou, Binhui Jiang
Summary: The study found that in E-bike-to-car accidents, the cyclist's head impact relative velocity and WAD of head impact location are higher than those in car-to-pedestrian accidents; increasing the initial impact velocity of the car can increase the cyclist's head relative impact velocity, WAD of head impact location, and HIC15; the WAD of cyclist's head impact location is significantly affected by the initial impact angle between E-bike and car and body size of cyclist.
ACCIDENT ANALYSIS AND PREVENTION
(2021)
Article
Computer Science, Interdisciplinary Applications
Karl-Johan Larsson, Bengt Pipkorn, Johan Iraeus, Jason Forman, Jingwen Hu
Summary: This study suggests the importance of evaluating all HBMs that should be morphed to represent a diverse population in vehicle safety evaluations. The morphed HBMs showed differences in kinetics and kinematics in collisions with different configurations, with closer correlation to obese subjects in frontal impacts.
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
(2022)
Article
Biophysics
Jiacheng Liu, Jionghua (Judy) Jin, James T. Eckner, Songbai Ji, Jingwen Hu
Summary: Tissue-level brain responses to sport-related head impacts may be stronger predictors of brain injury risk than head kinematics alone. This study developed subject-specific finite element (FE) head-brain models to estimate tissue-level brain impact responses under different head impact conditions, considering the influence of head morphological variations on brain tissue impact response. The study found that brain volume explained the largest variance of 51.3% and was highly correlated with maximal principal strain (MPS), indicating a significant size effect on brain impact responses.
JOURNAL OF BIOMECHANICS
(2022)
Article
Public, Environmental & Occupational Health
Jingwen Hu, Kathleen D. Klinich, Miriam A. Manary, Nichole Orton, Kyle Boyle, Yushi Wang, Kurt Fischer, Alex Smith, Angelo Adler
Summary: This study investigates the protection of wheelchair-seated occupants in side impacts and proposes a solution. By conducting sled tests and simulations, the study finds that using the CATCH design can effectively prevent occupants from falling off the wheelchair in far-side impacts. This research is significant for the protection of wheelchair-seated occupants.
TRAFFIC INJURY PREVENTION
(2022)
Article
Ergonomics
Kathleen D. Klinich, Kyle J. Boyle, Miriam A. Manary, Nichole R. Orton, Yushi Wang, Jingwen Hu
Summary: This study designed a frontal occupant protection system for an integrated second-row wheelchair seating station, including optimized airbags and seatbelt systems. Simulations and tests showed that the optimized seatbelt system geometry reduced the risk of injury for occupants, while the self-conforming rear seat airbag compensated for suboptimal geometry. The study provides specific recommendations for belt geometry and airbag parameters suitable for protecting wheelchair occupants.
ACCIDENT ANALYSIS AND PREVENTION
(2023)
Article
Ergonomics
Jingwen Hu, Carol Flannagan, Sailesh Ganesan, Patrick Bowman, Wenbo Sun, Iskander Farooq, Anil Kalra, Jonathan Rupp
Summary: The study aims to understand the distribution and mechanism of pedestrian injuries by analyzing recent pedestrian crash cases. It also examines the potential benefit of pedestrian automatic emergency braking (PedAEB) in reducing pedestrian injury risks through computational simulations. The study highlights the importance of future research on chest injury risk for pedestrian protection, considering the increased proportion of SUVs and pickup trucks in the vehicle fleet and the higher penetration of PedAEB.
ACCIDENT ANALYSIS AND PREVENTION
(2023)
Article
Ergonomics
Jingwen Hu, Kyle Boyle, Nichole Ritchie Orton, Miriam A. Manary, Matthew P. Reed, Kathleen D. Klinich
Summary: The study used computational models to investigate the impact of unconventional seating positions and orientations on child occupant response in vehicles with Automated Driving Systems. Sled tests and simulations were conducted with different child test dummies and restraint systems under various impact directions. The results showed that harnessed child restraint systems did not pose major safety concerns, but vehicle belt-restrained child test dummies had the potential to contact nearby seats or the instrument panel in side and angled impacts.
ACCIDENT ANALYSIS AND PREVENTION
(2023)
Article
Chemistry, Analytical
Zhiqiang Song, Libo Cao, Clifford C. Chou
