Article
Chemistry, Multidisciplinary
Hanan B. Howsaui, Abeer A. Sharfalddin, Magda H. Abdellattif, Amal S. Basaleh, Mostafa A. Hussien
Summary: Novel anti-cancer transition metal complexes were successfully synthesized and characterized using Schiff base derived from 2-aminopyrazine and salicylaldehyde. The complexes exhibited different structures and properties under different metal ions, showing promising anti-cancer activity. The Cu(II) complex showed practical results with HOP-62 cell lines, while the Zn(II) and Co(II) complexes demonstrated non-toxicity at doses up to 370 mg/kg based on LD50 values.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Inorganic & Nuclear
Naveen Dhingra, J. B. Singh, Har Lal Singh
Summary: In recent years, research on inorganic-based metallodrugs has provided an effective mechanism for choosing metals and their properties. In this study, six new organotin and organosilicon complexes containing sulphur and nitrogen donor atoms were synthesized and characterized. The results showed that these metal complexes were more effective against bacteria and fungi compared to the free ligand, with compound 6 exhibiting the highest binding affinity.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Physical
Gosu Nageswara Reddy, Venkatramana Losetty, C. Hazarathaiah Yadav
Summary: A Schiff base ligand and its metal complexes were synthesized and characterized using elemental analysis, powder X-ray diffraction, FTIR, 1 H NMR spectra, and thermal studies. The ligand behaves as isobidentate and charge transfer transitions are most centered on the ligand. Interesting fragmentation patterns were observed from thermal, biological activity, and docking studies. The Cu(II) complex exhibited a significantly more stable interaction and a lower binding energy compared to the ligand and other metal complexes.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Physical
Janusz Szklarzewicz, Anna Jurowska, Maciej Hodorowicz, Grzegorz Kazek, Monika Gluch-Lutwin, Jacek Sapa, Monika Papiez
Summary: This study presents the synthesis, properties, and biological activity of 16 new vanadium complexes with tridentate ONO Schiff base ligands based on 5-chloro- and 5-hydroxy-salicylaldehyde and selected hydrazides. Different types of complexes were synthesized at different oxidation states of vanadium and characterized using various spectroscopic methods. The stability of the complexes in solution and their inhibition of human tyrosine phosphatases were investigated and discussed.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Thermodynamics
Aniele de Moura, Jose Benedito Junior, Ana Carina Sobral Carvalho, Flavio Junior Caires
Summary: Schiff bases are organic compounds with broad biological activity and potential applications. This study focused on the synthesis of a Schiff base derived from 4-aminosalicylic acid and salicylaldehyde, as well as its metal complexes, using eco-friendly methods. Spectroscopic and thermal analysis techniques were used to characterize their structures and thermal behavior.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Chemistry, Physical
Mehmet Esref Alkis, Unzile Kelestemur, Yusuf Alan, Nevin Turan, Kenan Buldurun
Summary: A new Schiff base ligand and its metal complexes were synthesized and evaluated for their anticancer activities on colon cancer cells. The Co(II) and Ru(II) complexes showed significant anticancer properties, especially in combination with electrochemotherapy (ECT).
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Physical
Heba E. Hashem, Ashutosh Nath, Ajoy Kumer
Summary: The study focused on the synthesis, characterization, in vitro evaluation, and molecular dynamics study of Co(II) and Cu(II) metal containing Schiff base-metal complexes. The metal complexes showed higher antibacterial activity than the metal free ligands, with the highest activity observed against P. vulgaris. Computational tools, such as Density Functional Theory (DFT), molecular docking, and molecular dynamics, were used to evaluate the theoretical and biological activity, with results showing the Cobalt complex {L1-Co (4)} exhibiting the highest biological activity.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Inorganic & Nuclear
A. Z. El-Sonbati, M. A. Diab, Sh M. Morgan, S. Y. Abbas, Gehad G. Mohamed
Summary: A new series of transition metal complexes have been synthesized and characterized. The results show that these metal complexes have higher antibacterial and antifungal activity.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Review
Chemistry, Medicinal
Harshad R. Sonawane, Baliram T. Vibhute, Balasaheb D. Aghav, Jaydeep Deore, Sanjay K. Patil
Summary: In the past decade, there has been a significant increase in research on quinoline Schiff base metal complexes due to their versatile applications in various important fields. These complexes are employed in the biological, analytical, and catalytic domains. Researchers have found that Schiff bases exhibit enhanced biological activity when coordinated with metal ions. Quinoline and its derivatives, being heterocyclic compounds, have shown to be crucial in the field of biological sciences. These derivatives have been discovered to possess a broad spectrum of activity, making them effective therapeutic agents for various disorders.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Adel Z. El-Sonbati, Mostafa A. Diab, Ahmed K. El-Sayed, Mohamed Abou-Dobara, Sameh A. El-Sayad
Summary: Metal complexes of a Schiff base ligand derived from 2,4-dihydroxybenzaldehyde and p-nitroaniline were synthesized and characterized. The complexes showed antibacterial, antifungal, and cytotoxic activities, and the ligand exhibited high binding affinity to various receptors.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Taisiya A. Antonenko, Yulia A. Gracheva, Dmitry B. Shpakovsky, Mstislav A. Vorobyev, Dmitrii M. Mazur, Victor A. Tafeenko, Yury F. Oprunenko, Elena F. Shevtsova, Pavel N. Shevtsov, Alexey A. Nazarov, Elena R. Milaeva
Summary: A series of novel organotin(IV) complexes based on 2-(N-3 ',5 '-di-tert-butyl-4'-hydroxyphenyl)-iminomethylphenol (L) were synthesized and characterized. The crystal structures of L and complex 2 were determined. The complexes exhibited antioxidant, antiproliferative, and apoptosis-inducing activities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
Ayman A. Abdel A. Aziz, Ramadan M. M. Ramadan, Mina E. E. Sidqi, Mostafa A. A. Sayed
Summary: New mononuclear metal complexes derived from a tetradentate Schiff base ligand were successfully synthesized and characterized. The complexes exhibited strong binding affinity and antioxidant activity, particularly for Mn(II) and Cu(II) complexes. In vitro cell experiments demonstrated that the complexes had good anti-proliferative activity against tumor cells. The molecular geometry and DNA-interaction of the complexes were investigated using computational simulations and molecular docking experiments.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Applied
Dina A. Tolan, Tahani Kashar, Kazunari Yoshizawa, Ahmed M. El-Nahas
Summary: A novel hydrazide-hydrazone ligand derived from isonicotinic acid was synthesized and seven mononuclear complexes with Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), and Hg(II) were prepared and characterized. DFT studies were conducted to investigate the structures of the ligand and its complexes. The antimicrobial activities of the ligand and its complexes were compared, with the Hg(II) complex showing the best antibacterial and antifungal activity among all tested complexes.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Eyup Basaran, Hatice Gamze Sogukomerogullari, Resit Cakmak, Senem Akkoc, Tugba Taskin-Tok, Ayseguel Kose
Summary: Two chiral Schiff base ligands were synthesized and their corresponding metal complexes were prepared. The compounds were characterized by various analytical methods. The cytotoxic effects of these compounds on cancer cells and healthy cells were evaluated, and L1-Pd(II) was identified as a promising anticancer drug candidate. Molecular docking results revealed the interaction between L1-Pd(II) and colon cancer antigen protein.
BIOORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Priyanka Devi, Kiran Singh, Bhupender Kumar, Jahnavi Kumari Singh
Summary: Many pyrazoles-based Schiff bases were reported to exhibit high activity against bacterial, parasitic strains, and cancer cells. A new pyrazole based 'NO' bidentate ligand was synthesized and metal complexes with Co+2, Ni+2, Cu+2, and Zn+2 were also prepared. The characterization of the compounds and their metal complexes was performed, and the metal complexes showed enhanced activity compared to the ligand. They exhibited significant anticancer and antibacterial activity, as well as antifungal activity.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Applied
M. A. Diab, Gehad G. Mohamed, W. H. Mahmoud, A. Z. El-Sonbati, Sh. M. Morgan, S. Y. Abbas
APPLIED ORGANOMETALLIC CHEMISTRY
(2019)
Article
Chemistry, Applied
Eman Yossri Frag, Marwa El Badry Mohamed, Gehad G. Mohamed, Yasser Samy
APPLIED ORGANOMETALLIC CHEMISTRY
(2019)
Article
Chemistry, Applied
Walaa H. Mahmoud, M. M. Omar, Yasmin M. Ahmed, Gehad G. Mohamed
APPLIED ORGANOMETALLIC CHEMISTRY
(2020)
Article
Chemistry, Inorganic & Nuclear
Walaa H. Mahmoud, Reem G. Deghadi, Gehad G. Mohamed
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2020)
Article
Spectroscopy
Nadia G. Zaki, Walaa H. Mahmoud, Ahmed M. El Kerdawy, Abanoub Mosaad Abdallah, Gehad G. Mohamed
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2020)
Article
Chemistry, Multidisciplinary
Ola A. Shabaan, Hossam S. Jahin, Gehad G. Mohamed
ARABIAN JOURNAL OF CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Najlaa S. Al-Radadi, Ehab M. Zayed, Gehad G. Mohamed, Hayam A. Abd El Salam
JOURNAL OF CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Nadia G. Zaki, Walaa H. Mahmoud, Ahmed M. El Kerdawy, Abanoub Mosaad Abdallah, Gehad G. Mohamed
RESEARCH ON CHEMICAL INTERMEDIATES
(2020)
Article
Chemistry, Multidisciplinary
Walaa H. Mahmoud, Reem G. Deghadi, Gehad G. Mohamed
ARABIAN JOURNAL OF CHEMISTRY
(2020)
Article
Spectroscopy
Zh. E. Ozbekova, A. A. Abdyldaev, A. A. Kulmyrzaev
Summary: This study compared two drying methods for cow and yak muscles, finding that freeze drying caused less discoloration. Additionally, analysis of fluorescence spectra allowed for accurate prediction of chemical composition and color characteristics of the muscles.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Leo Mandic, Ivan Ljubic, Iva Dzeba
Summary: In this study, a combined experimental and computational approach was used to investigate the photoexcitation and photodegradation mechanisms of Doxazosin (DOX). The results provide valuable insights into the primary events following the photoexcitation of DOX and its potential applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiufeng Wang, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang, Ting Zhou, Fang Wang, Guodong Zhang
Summary: This study successfully synthesized near infrared fluorescence Ag2S quantum dots (QDs) and developed a dual-mode sensor for sulfide anion using the excellent oxidase-like characteristics of manganese dioxide (MnO2) nanosheets. The sensor showed a wider detection range, higher sensitivity, and shorter reaction time, making it suitable for highly selective detection of sulfide in different concentration ranges.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yafei Li, Yanming Ma, Chuantao Zheng, Di Yu, Lien Hu, Shuo Yang, Fang Song, Yadan Li, Shuanghai Liu, Zhanrui Zhang, Yu Zhang, Yiding Wang, Frank K. Tittel
Summary: To effectively monitor gas explosion and coal spontaneous combustion in coal mine, an intrinsically safe and explosion-proof dual-gas sensor system was developed for methane (CH4) and carbon monoxide (CO) measurement. The system achieved different measurement ranges using laser scanning and gas cells, and improved stability and accuracy through gas pre-treatment and temperature compensation algorithm.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Pei-Rong Chen, Li-Kang Chu
Summary: In this study, the hydrates of glyoxal were investigated using infrared absorption spectrometry. The results showed that at low concentrations, glyoxal mainly exists as monomeric dihydrate. These findings provide suitable detection windows for further research on the roles of glyoxal and its hydrates in atmospheric and aerosol chemistry, as well as the relevant reaction kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Nichole O'Neill, Thamires A. Lima, Fabio Furlan Ferreira, Nicolas J. Alvarez, Reinhard Schweitzer-Stenner
Summary: This study determines the main fibril axis of GHG gel-forming fibrils using various techniques and compares the results with simulated data. The analysis suggests that the hydrophobic xz-surfaces of GHG fibrils could be a good target for the adsorption of hydrophobic drugs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Mengyuan Liu, Hanchuang Zhu, Yikun Fang, Caiyun Liu, Xinke Li, Xiaohui Zhang, Lixue Ma, Kun Wang, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: ABHS is an efficient fluorescent probe that can accurately and sensitively detect Al3+ with strong resistance to interference. It also demonstrates excellent detection and imaging capabilities in complex real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Ahmed S. El-Shafie, Evana Rahman, Yasser Gadelhak, Rehab Mahmoud, Marwa El-Azary
Summary: The recycling of waste mandarin peels into biochar (MRBC) has been used as a high performance and cost-effective adsorbent for treating polluted wastewater effluents. Batch adsorption studies were conducted to analyze the adsorption competency of MRBC on two dyes, methylene blue (MB) and basic fuchsin (BF), either in individual solutions or binary combinations. The results showed that MRBC was capable of effectively removing a high percentage of both dyes. However, the adsorption capacity decreased when the dyes were combined. The cost estimation of MRBC production and wastewater treatment indicated that both were relatively low.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara, Sivaprasad Mitra
Summary: Derivatives of thiazole-pyrazole fused benzo-coumarin compounds were synthesized and their photophysical properties were investigated. The synthesized coumarin compounds showed potential as therapeutic agents for Alzheimer's disease, inhibiting acetylcholinesterase activity. The presence of human serum albumin was found to affect the inhibition activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yongwei Duan, Quancheng Liu, Yiju Zhu, Qi Zhang, Xiaohui Duan, Hu Deng, Liping Shang
Summary: In this study, the phase transition of CL-20 was observed using terahertz spectroscopy, and quantum chemical calculations were employed to analyze the vibrations. The results indicated changes in the vibrations of CL-20 before and after phase transition.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yuefeng Gao, Sai Xu, Baojiu Chen
Summary: This study synthesized Cs2NaInCl6 nanocrystals co-doped with Sb3+ and Tb3+ ions as probes for copper ions detection in lubricating oil. The introduction of Sb3+ effectively reduced the band gap of the host material and enabled energy transfer pathway for Tb3+ emission. The doped Tb3+ ions resulted in the suppression of emission due to electron transfer. The Cs2NaInCl6: 2.5 %Sb3+, 40 %Tb3+ NCs exhibited superior sensitivity and selectivity for copper ions detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yu Liu, Yue Zhang, Changyao Liu, Ce Wang, Baocai Xu, Li Zhao
Summary: A highly sensitive detection platform for heparin was developed using a cationic fluorescent dye (cresyl violet acetate) as a fluorescence probe. The platform demonstrated high selectivity towards heparin and achieved detection in both HEPES solution and serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Lopamudra Roy, Nivedita Pan, Susmita Mondal, Ria Ghosh, Md. Nur Hasan, Neha Bhattacharyya, Soumendra Singh, Kallol Bhattacharyya, Arpita Chattopadhyay, Samir Kumar Pal
Summary: The study focuses on the interaction between reactive oxygen species (ROS) and a spectroscopic probe called Rose Bengal (RB), encapsulated in nanoscopic sodium dodecyl sulphate (SDS) micelles and entrapped in microscopic nylon 66 solid matrix. The research demonstrates efficient interaction between ROS and RB-SDS, and investigates the mechanism of hydroxyl radicals generation. Based on these findings, a prototype device utilizing RB embedded in a nylon thin film for quantification of ROS in extracellular fluids and food materials was developed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiaosong Sun, Qihao Cui, Wenyue Dong, Qian Duan, Teng Fei
Summary: Conjugated porous polymers (CPPs) are promising sensing materials and their application in aqueous media is limited. In this study, we synthesized CPPs with porous structure and prepared nanoparticles, enabling efficient photoluminescence sensing of nitroaromatic explosives in aqueous phase.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Maria Cristina Caggiani, Germana Barone, Paolo Mazzoleni
Summary: Raman spectroscopy is commonly used for studying glassy materials in cultural heritage, but it is more difficult to interpret the spectra and apply the technique with portable instruments. In contrast, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) can be used in archaeometric investigations as it is portable and non-invasive. However, there is limited application of this technique to historical glasses. This exploratory work demonstrates the potential of DRIFTS, in combination with portable X-ray Fluorescence (pXRF) and EDS microanalyses, for studying the composition and alteration of glass samples in cultural heritage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)