Article
Medicine, General & Internal
Grant M. Russell, Katrina Long, Virginia Lewis, Joanne C. Enticott, Nilakshi Gunatillaka, I--Hao Cheng, Geraldine Marsh, Shiva Vasi, Jenny Advocat, Shoko Saito, Hyun Song, Sue Casey, Mitchell Smith, Mark F. Harris
Summary: The study aimed to investigate whether primary care outreach facilitation could enhance the quality of care for general practice patients from refugee backgrounds. The results showed that the intervention led to an increase in the proportion of refugee patients receiving Medicare-billed health assessments, but had limited impact on other aspects of care.
MEDICAL JOURNAL OF AUSTRALIA
(2021)
Article
Health Care Sciences & Services
Kelsey L. Grantham, Andrew B. Forbes, Richard Hooper, Jessica Kasza
Summary: This article introduces the 'staircase' design, which is a new experimental design method based on the zigzag pattern of steps. It can alleviate the burden on participating clusters, promote trial involvement, and reduce attrition. Although there is a lack of consistent methodology, we provide variance expressions for sample size and power calculations for the staircase designs.
STATISTICAL METHODS IN MEDICAL RESEARCH
(2023)
Article
Health Care Sciences & Services
Victoria J. Palmer, Patty Chondros, John Furler, Helen Herrman, David Pierce, Kali Godbee, Konstancja Densley, Jane M. Gunn
Summary: This study tested an adapted mental health experience codesign intervention to improve recovery-orientation of services, but found no difference in psychosocial recovery outcomes between the intervention and control arms. More attention is needed on the conditions required to support codesign processes and implementation.
HEALTH EXPECTATIONS
(2021)
Article
Critical Care Medicine
Claudia Spies, Nicolas Paul, Christine Adrion, Elke Berger, Reinhard Busse, Ben Kraufmann, Ursula Marschall, Simone Rosseau, Claudia Denke, Henning Krampe, Enrico Daehnert, Ulrich Mansmann, Bjoern Weiss
Summary: Supporting intensive care medicine through telehealth improves process quality and patient outcomes. A large-scale randomized controlled trial in Germany found that a telemedical program significantly increased adherence to German quality indicators in the intensive care units. Further research is needed to confirm these results in other healthcare systems.
INTENSIVE CARE MEDICINE
(2023)
Article
Health Care Sciences & Services
Richard Hooper
Summary: A stepped wedge trial is an evaluation method of implementing interventions over a staggered timetable, usually cluster randomized, with various designs and conduct practices. The analysis of this trial assumes a constant intervention effect and the need to adjust for period effects, underlying trends, and clustering of outcomes. The advantage lies in practicality or statistical efficiency.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2021)
Article
Psychiatry
N. M. den Bleijker, M. M. E. van Schothorst, I. J. M. Hendriksen, W. Cahn, N. K. de Vries, P. N. van Harten, J. Deenik
Summary: This study evaluates the effectiveness and implementation of a multidisciplinary lifestyle focused approach in the treatment of inpatients with mental illness. The primary outcome is to investigate the difference in the mean QRISK3 score of patients receiving the intervention compared to patients receiving TAU. Secondary outcomes include somatic and mental health outcomes, lifestyle factors, and implementation factors. Limitations of the study include missing data and the potential influence of external events, while strengths include focusing on effectiveness and implementation, and including perspectives from both patients and healthcare professionals.
Article
Nursing
Sven Ziegler, Claudia Schmoor, Lili M. Schoeler, Sam Schepputat, Eyere Takem, Birgit Grotejohann, Inga Steinbrenner, Johanna Feuchtinger
Summary: This study investigated the support of nurses in performing pressure-relieving repositioning in neurological and neurosurgical intensive care units using the MoMo sensor system, which records and visualises patients' movements in bed. The results showed that the system did not effectively reduce patients' immobility time or the incidence of new pressure ulcers.
Article
Medicine, Research & Experimental
Nazanin Falconer, David L. Paterson, Nancye Peel, Alyssa Welch, Christopher Freeman, Ellen Burkett, Ruth Hubbard, Tracy Comans, Leila Shafiee Hanjani, Elaine Pascoe, Carmel Hawley, Leonard Gray
Summary: This study aims to identify the impact of a set of sustainable, multimodal interventions in Australian residential aged care facilities targeting three common infection types, in order to optimize antimicrobial use.
Article
Mathematical & Computational Biology
Satya Prakash Singh
Summary: This study discusses the use of Bayesian methods in designing stepped wedge trials to address the issue of dependency among individuals. The robustness of Bayesian design is demonstrated by exploring various choices of priors, and its superiority over the commonly used balanced design is numerically demonstrated using hypothetical and real scenarios.
BIOMETRICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Laurence Caeymaex, Dominique Astruc, Valerie Biran, Leila Marcus, Florence Flamein, Stephane Le Bouedec, Bernard Guillois, Radia Remichi, Faiza Harbi, Xavier Durrmeyer, Florence Casagrande, Nolwenn Le Sache, Darina Todorova, Ali Bilal, Damien Olivier, Audrey Reynaud, Cecile Jacquin, Jean-Christophe Roze, Richard Layese, Claude Danan, Camille Jung, Fabrice Decobert, Etienne Audureau
Summary: A multiprofessional safety-promoting program in neonatal intensive care units (NICUs) can significantly reduce the rate of adverse events and severe and preventable adverse events in high-risk patients.
Article
Mathematical & Computational Biology
Jessica Kasza, Rhys Bowden, Richard Hooper, Andrew B. Forbes
Summary: Batched stepped wedge designs allow for staggered cluster recruitment, providing greater flexibility compared to standard designs. This approach helps reduce delays before a trial can start, improving efficiency in testing interventions across clusters.
STATISTICS IN MEDICINE
(2022)
Article
Surgery
Fabienne E. Stubenrouch, Loes J. Peters, Sylvana M. L. de Mik, Peter L. Klemm, Arnoud G. Peppelenbosch, Stella C. W. M. Schreurs, Dick M. Scharn, Dink A. Legemate, Ron Balm, Dirk T. Ubbink
Summary: Introduction of decision support tools improves the level of shared decision making in vascular surgery, increases patient knowledge, and shifts their preference towards more non-surgical treatments.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2022)
Article
Psychiatry
Aoife Carolan, Dolores Keating, Stephen McWilliams, Caroline Hynes, Mary O'Neill, Fiona Boland, Sharon Holland, Judith Strawbridge, Cristin Ryan
Summary: The aim of this research was to design and validate a medicines optimisation tool (OPTIMISE) to help clinicians improve the physical health of people with severe mental illness (SMI). A total of 62 prescribing indicators were developed and validated through a Delphi consensus methodology, with a substantial level of agreement between physicians and pharmacists. OPTIMISE has the potential to enhance medicines optimisation in this population.
Article
Public, Environmental & Occupational Health
Rachana Parikh, Adriaan Hoogendoorn, Daniel Michelson, Jeroen Ruwaard, Rhea Sharma, Bhargav Bhat, Kanika Malik, Rooplata Sahu, Pim Cuijpers, Vikram Patel
Summary: A single, lay counsellor-delivered, classroom sensitisation session can increase help-seeking behavior for common mental health problems among secondary school students in urban, low-income communities in India.
Article
Clinical Neurology
Fan Li, Rui Wang
Summary: This study provides an update on the design of stepped wedge randomized trials, including new methodological tools, for neurosurgeon scientists. The study highlights the indications for this design and discusses key considerations such as analysis methods and sample size determination.
WORLD NEUROSURGERY
(2022)
Article
Endocrinology & Metabolism
Elizabeth Holmes-Truscott, Jasmine Schipp, Trisha Dunning, John Furler, Virginia Hagger, Edith E. Holloway, Jo-Anne Manski-Nankervis, Jonathan E. Shaw, Timothy Skinner, Jane Speight
Summary: This qualitative study explores beliefs, attitudes, and experiences of injectable glucagon-like-peptide-1 receptor agonists (GLP-1RAs) use and discontinuation among adults with type 2 diabetes. The study found that expectations and experiences of GLP-1RAs were influenced by factors such as symbolism, ease of administration, treatment convenience, efficacy, and side effects. Some participants showed increased receptiveness to insulin therapy following their GLP-1RA experience, while others had unique concerns about insulin beyond injectable administration.
Article
Endocrinology & Metabolism
Xinyang Hua, Max Catchpool, Philip Clarke, Irene Blackberry, Jason Chiang, Elizabeth Holmes-Truscott, Alicia Jenkins, Kamlesh Khunti, David O'Neal, Jane Speight, John Furler, Jo-Anne Manski-Nankervis, Kim Dalziel
Summary: The study found that including professional-mode flash glucose monitoring every 3 months as part of a management plan for people with type 2 diabetes in general practice is not cost-effective, but could become cost-effective if the sensor price or monitoring frequency is reduced.
Article
Criminology & Penology
Kelsey Hegarty, Konstancja Densley, Gail Gilchrist, Peter Elliott, Jane Gunn
Summary: This study examined the trajectories of intimate partner violence (IPV) experienced by women over time and its impact on their mental health and quality of life. The findings suggest that IPV has a significant burden on women's mental health, except when the violence decreases. The study highlights the importance of clinical identification of IPV and tailored interventions to reduce the disease burden.
JOURNAL OF GENDER-BASED VIOLENCE
(2023)
Review
Nursing
Claire Hayes, Magenta Simmons, Victoria Palmer, Bridget Hamilton, Christine Simons, Malcolm Hopwood
Summary: Despite limited research on adolescent inpatient units, a proposed preliminary checklist can improve reporting consistency and guide the design of current inpatient and other mental health service models in Australia.
JOURNAL OF PSYCHIATRIC AND MENTAL HEALTH NURSING
(2023)
Editorial Material
Medicine, General & Internal
Jane M. Gunn, Alison Flehr
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Medicine, Research & Experimental
Michelle Tew, Max Catchpool, John Furler, Katie de la Rue, Philip Clarke, Jo-Anne Manski-Nankervis, Kim Dalziel
Summary: This study analyzes data from 25 general practices in Victoria, Australia and finds that assigning clinical staff to identify potential participants is the strongest factor associated with recruitment efficiency. The study also shows that smaller practices, rural locations, and areas of lower socioeconomic status tend to be more efficient. These findings provide helpful indications of site-level characteristics to improve feasibility and efficiency of conducting RCTs in general practice settings.
Article
Medicine, Research & Experimental
Sibel Saya, Patty Chondros, Anastasia Abela, Cathrine Mihalopolous, Mary Lou Chatterton, Jane Gunn, Timothy F. Chen, Thomas M. Polasek, Elise Dettmann, Rachel Brooks, Michelle King, Luke Spencer, Pavithran Alphonse, Shakira Milton, Georgia Ramsay, Zoe Siviour, Jamie Liew, Philip Ly, Matthew Thoenig, Raushaan Seychell, Floriana La Rocca, Luke B. Hesson, Nydia Mejias, Terri Sivertsen, Melanie Anne Galea, Chad Bousman, Jon Emery
Summary: This study aims to evaluate the impact of genomic-guided antidepressant prescribing on clinical efficacy and cost-effectiveness. It will be conducted in primary care settings and will primarily measure changes in depressive symptoms after 12 weeks, along with other secondary outcomes. The results will provide evidence to guide clinical practice.
Article
Psychology, Multidisciplinary
Melissa A. Russell, Nicola Reavley, Ian Williams, Wenjing Li, Laura Tarzia, Patty Chondros, Lena Sanci
Summary: Previous research has indicated that university students experienced substantial mental health issues during the global COVID-19 pandemic, but few studies have considered changes relative to pre-pandemic levels across population groups. This study compared changes in mental health and associated stressors across the pandemic for international and local university students studying in Australia. The findings showed that international students experienced an increase in depression, low social support, inability to afford food, race-based discrimination, and fear of partner compared to local students.
Article
Primary Health Care
Amy Coe, Jane Gunn, Susan Fletcher, Elizabeth Murray, Catherine Kaylor-Hughes
Summary: This study aimed to describe the self-reported reasons primary care patients have for reducing or stopping their antidepressant medication. The findings revealed several factors, including depression, medication, healthcare system, psychosocial, and financial reasons. These results can inform the development and implementation of discussions about antidepressant deprescribing in clinical practice.
PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT
(2023)
Article
Primary Health Care
Jon D. Emery, Mark A. Jenkins, Sibel Saya, Patty Chondros, Jasmeen Oberoi, Shakira Milton, Kitty Novy, Emily Habgood, Napin Karnchanachari, Marie Pirotta, Lyndal Trevena, Adrian Bickerstaffe, Richard De Abreu Lourenco, Anna Crothers, Driss Ait Ouakrim, Louisa Flander, James G. Dowty, Fiona M. Walter, Malcolm Clark, Sally Doncovio, Dariush Etemadmoghadam, George Fishman, Finlay Macrae, Ingrid Winship, Jennifer G. McIntosh
Summary: Using a risk assessment and decision support tool can increase the rate of risk-appropriate colorectal cancer screening. It is important to start screening for colorectal cancer at the appropriate age and choose the most cost-effective testing method.
BRITISH JOURNAL OF GENERAL PRACTICE
(2023)
Article
Criminology & Penology
Kelsey Hegarty, Konstancja Densley, Gail Gilchrist, Peter Elliott, Jane Gunn
Summary: This study examines the trajectories of women's experience of intimate partner violence (IPV) over time and identifies different groups based on these trajectories. The results show that a significant proportion of women have experienced IPV in the past year. Different patterns of IPV trajectories are associated with varying levels of mental health, quality of life, and social support outcomes.
JOURNAL OF GENDER-BASED VIOLENCE
(2023)
Article
Primary Health Care
Mary Lou Chatterton, Meredith Harris, Philip Burgess, Susan Fletcher, Matthew J. Spittal, Jan Faller, Victoria J. Palmer, Patty Chondros, Bridget Bassilios, Jane Pirkis, Jane Gunn, Cathrine Mihalopoulos
Summary: This paper presents the cost-effectiveness evaluation of Link-me, a digitally supported approach to triaging care for depression and anxiety in primary care. The findings suggest that Link-me shows a trend towards cost-effectiveness by providing improvement in mental health symptoms at an additional cost.
