Article
Health Care Sciences & Services
Sung Ho Jang, Min Jye Cho
Summary: This study investigated the relationship between the nigrostriatal tract (NST) and the corticospinal tract (CST) with motor function in chronic hemiparetic stroke patients. The results showed a strong positive correlation between the tract volume of ipsilesional NST and fractional anisotropy and the tract volume of ipsilesional CST with the Motricity Index score. The study also found that NST indirectly influenced the motor function of affected extremities through CST.
Article
Medicine, General & Internal
Sung Ho Jang, Sang Seok Yeo, Min Jye Cho
Summary: This study investigated the predictability of the nigrostriatal tract and corticoreticulospinal tract in the early stage of cerebral infarction for gait function in the chronic stage. The results showed a strong positive correlation between the tract volumes of these tracts in the early stage and the functional ambulation category scores in the chronic stage. The corticoreticulospinal tract had stronger predictability than the nigrostriatal tract.
Review
Neurosciences
Sung Ho Jang, Min Jye Cho
Summary: This review discusses the role of the contra-lesional corticoreticular tract (CRT) in motor recovery of the paretic leg in stroke patients. The studies reviewed suggest that the contra-lesional CRT can contribute to motor recovery in stroke patients, particularly in those with complete injuries of the corticospinal tract and CRT on the same side. The recovery of the paretic ankle dorsiflexor, important for achieving a good gait pattern, was also found to be closely related to the contra-lesional CRT.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Medicine, General & Internal
In Jun Han, Hyeok Gyu Kwon, Woong-Woo Lee, Ra Gyoung Yoon, Hyoseon Choi, Hyun Jung Kim
Summary: This paper describes the changes over time in the corticobulbar tract (CBT) using diffusion tensor tractography (DTT) in a dysphagic patient with progressive supranuclear palsy (PSP). The patient initially presented with dysarthria, gait disturbance, and bradykinesia, and later developed dysphagia symptoms. DTI imaging showed progressive thinning of the CBTs. This study suggests that analyzing the CBT using DTT can help predict the degree of dysphagia and prognosis in PSP patients.
Article
Neurosciences
Mengxing Liu, Garikoitz Lerma-Usabiaga, Francisco Clasca, Pedro M. Paz-Alonso
Summary: In this study, a reconstruction protocol based on in vivo diffusion MRI was developed to extract and measure specific axonal fiber tracts in individual first-order relay nuclei. The protocol demonstrated high computational and test-retest reproducibility. This new protocol is significant for both basic human brain neuroscience and clinical studies.
Article
Clinical Neurology
Yang Yang, Marian C. Neidert, Julia Velz, Vincens Kalin, Johannes Sarnthein, Luca Regli, Oliver Bozinov
Summary: This study investigated the continuous mapping of the corticospinal tract (CST) through direct brainstem stimulation and explored the relationship between stimulation intensity and the shortest distance from the stimulation point to the CST (DS-to-T). In a cohort of 30 patients, successful direct brainstem stimulation was performed, and postoperative imaging was used to evaluate the CST status and measure DS-to-T. The results demonstrated a correlation between stimulation intensity and DS-to-T, with a certain sensitivity and specificity.
Article
Medicine, General & Internal
Jeong-Pyo Seo, Heun Jae Ryu
Summary: Using diffusion tensor tractography (DTT), this study explored the aging of the mesolibic tract (MLT) in normal human participants and found a significant negative correlation between age and the voxel number (VN) of MLT, as well as a positive correlation between age and the apparent diffusion coefficient (ADC). Aging of MLT was observed to begin in the 20s or 30s and steadily progress throughout life until significant degeneration occurred in the 60s. This may play a role in the decline of memory and social interaction with aging in normal participants.
Article
Medicine, General & Internal
Sung Ho Jang, Sung Jun Lee, Min Jye Cho
Summary: This study investigated the relationship between consciousness and the thalamocortical tract in patients with intracerebral hemorrhage (ICH). The results showed that the volume of the thalamocortical tract was significantly correlated with the consciousness level in ICH patients. This finding could be helpful for developing therapeutic strategies for ICH patients with consciousness disorders.
Article
Medicine, General & Internal
Sung Ho Jang, Seong Ho Kim, Hyeok Gyu Kwon
Summary: This study found a high diagnostic sensitivity of traumatic axonal injury (TAI) of the spinothalamic tract (STT) in patients with mild traumatic brain injury (TBI) suffering from central pain symptoms using diffusion tensor tractography (DTT). However, the generalizability of the study results may be limited by the small number of subjects who visited the university hospital and the constraints of DTT technology.
Article
Medicine, General & Internal
Sung Ho Jang, Han Do Lee
Summary: In this study, injury of the CPCT was investigated in patients with mild TBI using DTT, demonstrating differences in FA and FN values among patient groups. The findings suggest the utility of DTT for evaluating CPCT in patients with ataxia after mTBI, where conventional brain MRI may not reveal abnormalities.
Article
Medicine, General & Internal
Sung Ho Jang, Eun Bi Choi
Summary: This study found differences in the thalamocortical tract between vegetative state (VS) and minimally conscious state (MCS) patients with hypoxic-ischemic brain injury (HI-BI), particularly in the prefrontal cortex and posterior parietal cortex.
Article
Neurosciences
Sang Seok Yeo, Seo Yoon Park, In Hee Cho
Summary: In this study, the authors used diffusion tensor imaging (DTI) to investigate the injury of the vestibulocerebellar tract (VCT) in a patient with intracerebral hemorrhage (ICH). They found that the patient's ataxia may be related to the injury of the VCT. This study provides important insights for evaluating and managing patients with ataxia following cerebellar injury.
NEUROSCIENCE LETTERS
(2022)
Article
Clinical Neurology
J. Levi Chazen, Mihaela Stavarache, Michael G. Kaplitt
Summary: Magnetic resonance-guided focused ultrasound is a promising technology for noninvasive treatment of complex brain disorders, but faces challenges in achieving optimal intraoperative imaging, technical limitations, and regulatory barriers that hinder widespread application.
WORLD NEUROSURGERY
(2021)
Review
Health Care Sciences & Services
Sung Ho Jang, Sang Seok Yeo, Eun Bi Choi
Summary: Aphasia is a common and serious clinical feature of stroke, and neural tracts play an important role in the recovery mechanisms. Although there have been studies on the recovery mechanisms of aphasia in stroke, there are still many factors that have not been elucidated, and further research is needed to explore them.
Article
Medicine, General & Internal
Sang-Seok Yeo, Seung-Min Nam, In-Hee Cho
Summary: This study aimed to compare cerebellar dysfunction according to vestibulocerebellar tract (VCT) damage in patients with cerebellar stroke. Ataxia was found to be related to secondary VCTs, and hand dysfunction was also related to VCTs.
JOURNAL OF CLINICAL MEDICINE
(2023)
