4.6 Article

Controlled self-assembly of alpha-helix-decorated peptide nanostructures

期刊

SOFT MATTER
卷 7, 期 5, 页码 1675-1677

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0sm01275k

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资金

  1. National Research Foundation (NRF) [2010-0019102]
  2. Basic Science Research Program [2010-0015374, 2010-0016145]
  3. Translational Research Center for Protein Function Control, Yonsei University [2010-0001933]

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This study describes a strategy to control the degree of alpha-helix stabilization and the shape of alpha-helix-decorated nanostructures. Coassembly of a macrocyclic peptide and a beta-sheet peptide diminished steric clashes between helical peptide segments, further stabilizing alpha-helices.

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