期刊
SOFT MATTER
卷 7, 期 18, 页码 8002-8004出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1sm05805c
关键词
-
类别
资金
- Bulgarian National Science Fund [DO 02-247/2008]
The complex between polycation-containing thermally sensitive block copolymer and DNA (polyplex) was stabilized utilizing a seeded radical copolymerization in aqueous media under mild conditions. Thus, the DNA molecule was encapsulated into the core of a stable nanoparticle with a cross-linked polymer shell and size of similar to 100 nm. The versatility of the proposed approach was demonstrated through the introduction of targeting and biodegradable functions during the polymer shell formation providing an opportunity to construct gene carriers that are able to satisfy the conflicting requirements of adequate DNA protection and efficient release into the target cell.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据