Article
Multidisciplinary Sciences
Antonello Pellicano, Gianluca Mingoia, Christoph Ritter, Giovanni Buccino, Ferdinand Binkofski
Summary: The Mirror Neurons System (MNS) plays a crucial role in understanding the action goals of others, particularly during walking. Bilateral SMA is considered responsible for the core MNS effect for walking, while bilateral parietal opercula modulate respiratory function during walking execution-observation-imagination.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Riccardo Viaro, Emma Maggiolini, Emanuele Farina, Rosario Canto, Atsushi Iriki, Alessandro D'Ausilio, Luciano Fadiga
Summary: Mirror neurons, which respond when an individual performs an action and when observing others doing the same action, were found in both non-human primates and rats. The specificity of mirror responses suggests a fundamental role in action processing and cognitive functions. The discovery of mirror properties in rats opens up new avenues for studying sensorimotor representations and the effects of deprivation on sensorimotor development.
Article
Clinical Neurology
Luca Vigano, Henrietta Howells, Marco Rossi, Marco Rabuffetti, Guglielmo Puglisi, Antonella Leonetti, Andrea Bellacicca, Marco Conti Nibali, Lorenzo Gay, Tommaso Sciortino, Gabriella Cerri, Lorenzo Bello, Luca Fornia
Summary: The activity of frontal motor areas during hand-object interaction is coordinated by specific white matter pathways. Direct electrical stimulation on these pathways can disrupt hand-muscle activity during task execution. The disruption patterns differ depending on the stimulated region, indicating distinct functional roles of the dorsal and ventral frontal white matter regions. Resections in the dorsal white matter region surrounding the supplementary motor area may result in transient upper-limb deficit.
Article
Psychology, Experimental
E. R. Palser, J. Glass, A. Fotopoulou, J. M. Kilner
Summary: The study found that there is synchronization between heartbeats and movements during both action execution and observation, with observers exhibiting off-phase heartbeats with movement culmination. This suggests a coordination between an action executioner's cardiac cycle and the timing of their movements, which is mirrored in an observer.
Article
Physiology
Alexander I. Kostyukov, Andriy V. Gorkovenko, Yurii A. Kulyk, Oleksii V. Lehedza, Dmytro I. Shushuiev, Mariusz Zasada, Serhii S. Strafun
Summary: This study examines the non-linear effects of signal transduction in the human motor system, specifically focusing on muscle hysteresis. The results show that for two-joint movements of the forelimbs, considering force and activation synergies is sufficient, while kinematic synergy acts as a potent modulator of activation synergy.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Engineering, Biomedical
Minji Lee, Ji-Hoon Jeong, Yun-Hee Kim, Seong-Whan Lee
Summary: The classification performance of motor imagery in stroke patients is higher than in healthy controls, indicating better neural control during motor imagery for stroke patients. However, there is no significant difference between the accuracies of motor execution and motor imagery, suggesting the need for further research into this area.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Greta Sokoloff, James C. Dooley, Ryan M. Glanz, Rebecca Y. Wen, Meredith M. Hickerson, Laura G. Evans, Haley M. Laughlin, Keith S. Apfelbaum, Mark S. Blumberg
Summary: Twitching during sleep is important for the development of the sensorimotor system, and the relationship between twitching and sleep spindles strengthens with age.
Article
Neurosciences
Paul Rinnert, Andreas Nieder
Summary: The study found that neurons in the NCL region of crows play a crucial role in action planning and execution, predicting motion direction, representing target locations, and tuning to specific target locations during movement execution.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Psychology, Experimental
Laila Craighero, Sonia Mele
Summary: The study found that observers exhibit proactive gaze when observing both biological and non-biological motions, even in the presence of barriers. Proactive gaze is also present when an object is present at the end point of the movement trajectory. Therefore, the involvement of the observer's motor system is not only dependent on the natural kinematics of the agent, but also on the presence of a goal or agent.
Article
Psychology, Biological
Alessio D'Aquino, Cornelia Frank, John Elvis Hagan Jr, Thomas Schack
Summary: Previous research has focused on the congruency in gaze metrics between action execution (AE) and motor imagery (MI), with limited evidence on the changes in gaze parameters during imagery with more dynamic task demands. This study compared eye movements during AE and MI for an interception task, and found that MI was characterized by higher smooth pursuit gain and duration, while other parameters showed no meaningful differences.
Article
Hospitality, Leisure, Sport & Tourism
S. Romano-Smith, J. W. Roberts, G. Wood, G. Coyles, C. J. Wakefield
Summary: Combining the motor simulation techniques of action observation and motor imagery (AOMI) has been shown to enhance motor performance. This study examined the involvement of lower-level sensorimotor processes in the improvement of a dart-throwing task using AOMI. Results showed that simultaneous and alternate congruent groups had significantly improved dart-throwing performance compared to control groups. This improvement was accompanied by lower EMG activity, suggesting greater movement efficiency. AOMI involves a common lower-level sensorimotor process that can lead to motor facilitation or interference, depending on the congruency of the simulation techniques, regardless of the delivery structure.
PSYCHOLOGY OF SPORT AND EXERCISE
(2022)
Article
Psychology, Multidisciplinary
Melissa Lajtos, Luis Alberto Barradas-Chacon, Selina Christin Wriessnegger
Summary: This study investigates the influence of handedness on brain activation during the processes of imagining and executing simple hand movements. The results show that both left-handed and right-handed individuals exhibit activation over sensorimotor areas. However, the right-handed group tends to display more bilateral patterns than the left-handed group, which contradicts previous findings. Additionally, there is a stronger activation during motor imagery than during motor execution in both groups.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Neurosciences
Ricardo A. Wilhelm, A. Hunter Threadgill, Philip A. Gable
Summary: The study found that motor preparation is enhanced prior to more challenging tasks but declines as participants become closer to completing their goal in each challenging trial. This suggests that participants have more motor preparation when facing more challenging tasks and it decreases as the tasks progress.
Article
Biochemistry & Molecular Biology
Carolina G. Ferroni, Davide Albertini, Marco Lanzilotto, Alessandro Livi, Monica Maranesi, Luca Bonini
Summary: This research investigated the neural activity in the action observation network (AON) during self and others' action encoding, revealing temporal and tuning specificities of distinct brain areas and neuronal classes. Different areas within AON showed varied prevalence of facilitated and suppressed neurons during task execution and observation, with distinct cell classes carrying specific visuomotor signals. The findings elucidated the firing properties and time course of activity at both system and local levels in the AON.
Review
Cell Biology
Zhen Xie, Mengyuan Zhao, Chengxiang Yan, Wei Kong, Fei Lan, Shuxuan Zhao, Qinghu Yang, Zhantao Bai, Hong Qing, Junjun Ni
Summary: Cathepsin B (CatB), a cysteine protease, is primarily located in the subcellular endosomal and lysosomal compartments and is involved in the degradation of intracellular and extracellular proteins. It plays diverse roles in physiological and pathological processes, including programmed cell death (PCD). However, CatB-mediated PCD can lead to disease progression under pathological conditions. This review provides an overview of the critical roles and regulatory pathways of CatB in different types of PCD, and discusses its potential as a therapeutic target in multiple diseases. Current gaps in understanding CatB's involvement in PCD are also highlighted to guide future research directions.
CELL DEATH & DISEASE
(2023)
Article
Neurosciences
Antonella Leonetti, Guglielmo Puglisi, Roma Siugzdaite, Clarissa Ferrari, Gabriella Cerri, Paola Borroni
EXPERIMENTAL BRAIN RESEARCH
(2015)
Article
Biology
Francesco della Gatta, Francesca Garbarini, Guglielmo Puglisi, Antonella Leonetti, Annamaria Berti, Paola Borroni
Article
Multidisciplinary Sciences
Guglielmo Puglisi, Antonella Leonetti, Ayelet Landau, Luca Fornia, Gabriella Cerri, Paola Borroni
Article
Neurosciences
Paola Borroni, Marcella Montagna, Gabriella Cerri, Fausto Baldissera
EUROPEAN JOURNAL OF NEUROSCIENCE
(2008)
Article
Neurosciences
Paola Borroni, Alessandra Gorini, Giuseppe Riva, Stephane Bouchard, Gabriella Cerri
EUROPEAN JOURNAL OF NEUROSCIENCE
(2011)
Article
Neurosciences
Gabriella Cerri, Monia Cabinio, Valeria Blasi, Paola Borroni, Antonella Iadanza, Enrica Fava, Luca Fornia, Valentina Ferpozzi, Marco Riva, Alessandra Casarotti, Filippo Martinelli Boneschi, Andrea Falini, Lorenzo Bello
HUMAN BRAIN MAPPING
(2015)
Article
Neurosciences
Monia Cabinio, Valeria Blasi, Paola Borroni, Marcella Montagna, Antonella Iadanza, Andrea Falini, Gabriella Cerri
Article
Neurosciences
G. Cerri, M. Montagna, L. Madaschi, D. Merli, P. Borroni, F. Baldissera, A. Gorio
Article
Neurosciences
P Borroni, M Montagna, G Cerri, F Baldissera
Article
Neurosciences
M Montagna, G Cerri, P Borroni, F Baldissera
EUROPEAN JOURNAL OF NEUROSCIENCE
(2005)
Article
Psychology
B Tomasino, P Borroni, A Isaja, RI Rumiati
COGNITIVE NEUROPSYCHOLOGY
(2005)
Article
Neurosciences
P Borroni, G Cerri, F Baldissera
Article
Neurosciences
G Cerri, P Borroni, F Baldissera
JOURNAL OF NEUROPHYSIOLOGY
(2003)
Article
Neurosciences
F Baldissera, P Borroni, P Cavallari, G Cerri
JOURNAL OF PHYSIOLOGY-LONDON
(2002)