Spatial Confined Synergistic Enzymes with Enhanced Uricolytic Performance and Reduced Toxicity for Effective Gout Treatment

A Hepatocyte-Mimicking Antidote for Alcohol Intoxication

(2018) Duo Xu et al.   ADVANCED MATERIALS

Ultralong-Discharge-Time Biobattery Based on Immobilized Enzymes in Bilayer Rolled-Up Enzymatic Nanomembranes

(2018) Bo Liu et al.   Small

Bioresponsive Microneedles with a Sheath Structure for H2 O2 and pH Cascade-Triggered Insulin Delivery

(2018) Yuqi Zhang et al.   Small

Engineering Potato Virus X Particles for a Covalent Protein Based Attachment of Enzymes

(2017) Juliane Röder et al.   Small

Phosphorylcholine polymer nanocapsules prolong the circulation time and reduce the immunogenicity of therapeutic proteins

(2016) Sheng Liang et al.   Nano Research

Prolonging the plasma circulation of proteins by nano-encapsulation with phosphorylcholine-based polymer

(2016) Linlin Zhang et al.   Nano Research

A Nanostructured Conductive Hydrogels-Based Biosensor Platform for Human Metabolite Detection

(2015) Lanlan Li et al.   NANO LETTERS

Global epidemiology of gout: prevalence, incidence and risk factors

(2015) Chang-Fu Kuo et al.   Nature Reviews Rheumatology

Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance

(2015) Lang Rao et al.   Small

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

(2014) Jan Mauer et al.   NATURE IMMUNOLOGY

Methaemoglobinaemia and haemolysis following pegloticase infusion for refractory gout in a patient with a falsely negative glucose-6-phosphate dehydrogenase deficiency result

(2014) Laura Geraldino-Pardilla et al.   RHEUMATOLOGY

Zwitterionic-Coated “Stealth” Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System

(2014) Karina Pombo García et al.   Small

Biomimetic enzyme nanocomplexes and their use as antidotes and preventive measures for alcohol intoxication

(2013) Yang Liu et al.   Nature Nanotechnology

Multi-enzyme systems: bringing enzymes together in vitro

(2011) Sanne Schoffelen et al.   Soft Matter

Update on gout: new therapeutic strategies and options

(2010) Robert Terkeltaub   Nature Reviews Rheumatology

Stability of Protein Pharmaceuticals: An Update

(2010) Mark Cornell Manning et al.   PHARMACEUTICAL RESEARCH

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

A novel intracellular protein delivery platform based on single-protein nanocapsules

(2009) Ming Yan et al.   Nature Nanotechnology

Quality of life and quality of care for patients with gout

(2009) Jasvinder A. Singh   Current Rheumatology Reports

A critical reappraisal of allopurinol dosing, safety, and efficacy for hyperuricemia in gout

(2009) Jeannie Chao et al.   Current Rheumatology Reports

Long-term Cardiovascular Mortality Among Middle-aged Men With Gout

(2008) Eswar Krishnan   ARCHIVES OF INTERNAL MEDICINE