Article
Spectroscopy
Mariusz Sandomierski, Marcel Jakubowski, Maria Ratajczak, Adam Voelkel
Summary: The paper presents a new method of modifying titanium alloy by creating bioactive titanate layers containing various divalent ions and coordinated with ciprofloxacin. The distribution of the antibiotic on the alloy surface was determined, and the release profiles of ciprofloxacin were studied. The results indicate that this modification method can be used for titanium implants, providing the advantage of sustained antibiotic release and potentially reducing perioperative infections.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Chemistry, Physical
Katerina Vrchovecka, Adam Weiser, Jan Pribyl, Jan Kuta, Jakub Holzer, Monika Pavkova-Goldbergova, Dinara Sobola, Antonin Dlouhy
Summary: This study investigates the release of Ti-ions from four different surface oxides into a liquid Dulbecco Modified Eagle Medium. Despite differences in structure, the concentration of Ti-ions released from the four oxides was similar, suggesting that the solubility limit in the medium plays a key role in the transfer of Ti-ions.
SURFACES AND INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Agata Sotniczuk, Halina Garbacz
Summary: This article summarizes several strategies proposed in recent years to optimize the properties of nanostructured titanium products for dental applications, including bulk modifications, surface modifications, and deposition of bioactive coatings. Additionally, insights are provided on how changes in microstructure induced by the fabrication of nanograined Ti can be successfully exploited to improve surface properties.
ADVANCED ENGINEERING MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Dan Li, Danyang Wang, Yulu Yang, Pengfei Gao, Wuzhe Fan, Xianhui Zhang, Yu Tang, Weihu Yang, Kaiyong Cai
Summary: In this study, the genomic characteristics of osteonecrosis of the femoral head (ONFH) were analyzed, and differentially expressed genes (DEGs) related to autophagy were identified. A modified titanium substrate was designed to upregulate HIF-1 alpha expression in mesenchymal stem cells (MSCs) and human umbilical vein endothelial cells (HUVECs) through receptors of TGF-beta and TNFR. The upregulated HIF-1 alpha in MSCs promoted autophagy and regulated MSCs proliferation and osteogenic differentiation, while in HUVECs, it accelerated angiogenesis by increasing VEGF expression. The modified titanium substrate enhanced the integration effect of the implant and reta\rded the deterioration of ONFH.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Richard Bright, Andrew Hayles, Daniel Fernandes, Rahul M. Visalakshan, Neethu Ninan, Dennis Palms, Anouck Burzava, Dan Barker, Toby Brown, Krasimir Vasilev
Summary: The development of a nanostructured titanium surface shows promising results in reducing the viability of Staphylococcus aureus and Pseudomonas aeruginosa, potentially reducing implant infection rates.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Andrew Hayles, Richard Bright, Jafar Hasan, Jonathan Wood, Dennis Palms, Dan Barker, Krasimir Vasilev
Summary: The risk of medical device associated infection highlights the need for novel anti-infective materials. The study demonstrates that surfaces with sharp nanostructures can effectively kill bacteria, even in mixed species infections. This has the potential to minimize the burden of infections containing more than one species and provides a foundation for further research into biointerfacial interactions.
ADVANCED MATERIALS INTERFACES
(2022)
Review
Chemistry, Physical
Jakub Litak, Michal Szymoniuk, Wojciech Czyzewski, Zofia Hoffman, Joanna Litak, Leon Sakwa, Piotr Kamieniak
Summary: In the past decade, there have been advancements in pedicle fixation systems and spinal fusion techniques to improve fusion rates and clinical outcomes. Titanium alloys are the most popular materials used for screw and rod manufacturing. Other materials, such as hydroxyapatite and tantalum, can also be added to enhance the biomaterial. The ideal implant for lumbar interbody fusion should have high mechanical strength, similar elasticity to bone, and be corrosion-resistant. The biological response to implanted materials plays a crucial role in fusion and wound healing.
Review
Biochemistry & Molecular Biology
Anna M. Brudzisz, Damian Gizinski, Wojciech J. Stepniowski
Summary: Anodic oxidation of metals leads to the formation of ordered nanoporous or nanotubular oxide layers, playing a significant role in various applications. However, there are still many fundamental aspects of anodizing that require deeper understanding. The inevitable phenomenon of anion incorporation during metal anodization and its impact on properties are discussed in detail in this review.
Article
Materials Science, Biomaterials
Alexander A. Matchin, Evgeniy V. Nosov, Alexander A. Stadnikov, Gennadiy V. Klevtsov, Luiza R. Rezyapova, Natalia A. Sayapina, Elena V. Blinova, Ruslan Z. Valiev
Summary: This study focuses on the osseointegration behavior of medical implants made from nanostructured grade 4 titanium in maxillofacial surgery. The results show that nanotitanium implants have a significantly faster fixation rate due to osseointegration compared to standard factory-made implants, indicating better osseointegration for nanotitanium implants.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Review
Engineering, Biomedical
Pinliang Jiang, Yanmei Zhang, Bin Shi, Lihai Zhang, Qiaoling Huang, Yun Yang, Peifu Tang, Changjian Lin
Summary: Titanium (Ti) and its alloys are widely used as orthopedic implants due to their favorable mechanical properties, corrosion resistance, and biocompatibility. However, the failure, degradation, and revision rates are high in patients with low bone density, insufficient quantity of bone or osteoporosis. Therefore, surface modification of Ti is actively studied to improve clinical outcomes. This review discusses the surface characteristics of Ti materials, conventional surface modification techniques, and emerging dynamic responsive avenues for improving bioactivity and biocompatibility of Ti implants.
BIOACTIVE MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Jiliang Zhang, Gi-Hyeok Lee, Vincent Wing-hei Lau, Feng Zou, Yingmin Wang, Xuelian Wu, Xun-Li Wang, Chi-Liang Chen, Chun-Jen Su, Yong-Mook Kang
Summary: The study suggests that rapid conversion reactions in high-rate cycling can lead to reduced crystallite size and the formation of Fe-Fe-Fe medium-range ordering in alpha-Fe2O3 electrodes, resulting in higher capacity and improved performance.
Article
Materials Science, Ceramics
Pei-Hsuan Chan, Huang-Ping Teng, Hsun-Shu Chan, Fu-Hsing Lu
Summary: Barium strontium titanate (BaxSr1-xTiO3; BST) thin films were successfully produced on TiN-coated Si substrates by a hydrothermal-galvanic couple (HT-GC) method in alkaline solutions containing Ba(CH3COO)2 and Sr(CH3COO)2. The films exhibited a promising dielectric tunability that could reach as high as 92%, with Sr ions more readily incorporated into the films than Ba ions, leading to a transition from Sr-rich to Ba-rich BST as the mole fraction of Ba2+ in the reaction solutions increased. The epitaxial-like growth of (111) BST films over (111)-oriented TiN underlayer was observed for all obtained films.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Multidisciplinary
Vadim Sirotkin
Summary: The molecular dynamics simulation of accelerated argon cluster ions interacting with rutile surfaces was conducted. The study revealed a strong influence of the anisotropy of rutile's mechanical properties on the amount of sputtered material and the characteristics of impact craters and damaged layers. The simulation also considered the evolution of the surface relief and damaged layer caused by successive impacts of cluster ions, providing insights for analyzing experimental results obtained by treating titanium implants with a beam of argon cluster ions covered with a layer of rutile.
Article
Materials Science, Multidisciplinary
Nesrine Ben Saber, Amine Mezni, Arwa Alrooqi, Tariq Altalhi
Summary: Hybrid titanium dioxide nickel titanate perovskite nanomaterials and gold nanoparticles supported on hybrid titania@nickel titanate were successfully synthesized using a modified solvothermal wet chemical procedure. The obtained nanocomposites exhibit good optical response and sensitivity to heat treatment. These materials show efficient photocatalytic activity against dye molecules, with Au/TiO2@NiTiO3 displaying superior efficiency for potential applications in photovoltaic devices and solar cells.
MATERIALS RESEARCH EXPRESS
(2021)
Article
Chemistry, Physical
Nikita Kazarinov, Andrey Stotskiy, Alexander Polyakov, Ruslan Z. Valiev, Nariman Enikeev
Summary: This study presents the simulation-driven design of medical implants fabricated of nanostructured commercially pure Ti with significantly enhanced mechanical properties, providing hope for the design of a new generation of medical products.
Article
Chemistry, Multidisciplinary
Xiangmei Liu, Ruhua Li, Xueli Xu, Yangyang Jiang, Wenjuan Zhu, Yu Yao, Feiyang Li, Xiaofang Tao, Shujuan Liu, Wei Huang, Qiang Zhao
Summary: Scintillator-based X-ray imaging has been developed using lanthanide(III)-Cu4I4 heterometallic organic frameworks (Ln-Cu4I4 MOFs) which consist of X-ray absorption centers ([Cu4I4] clusters) and luminescent chromophores (Ln(III) ions). The [Cu4I4] clusters absorb X-ray energy to generate triplet excitons through halide-to-ligand charge transfer (XLCT) and metal-to-ligand charge transfer (MLCT) state. These excitons excite Tb3+ to produce intense X-ray-excited luminescence through energy transfer. Tb-Cu4I4 MOFs exhibit high resistance to humidity and radiation, linear response to X-ray dose rate, and high X-ray relative light yield. X-ray imaging with Tb-Cu4I4 MOFs-based flexible scintillator film shows high spatial resolution.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yunfang Tong, Xiaoying Bi, Shuang Xu, Hao Min, Lu Cheng, Zhiyuan Kuang, Lingzhi Yuan, Fuyi Zhou, Ying Chu, Lei Xu, Lin Zhu, Ni Zhao, Nana Wang, Wei Huang, Jianpu Wang
Summary: An in situ halide exchange method is developed to achieve efficient and bright deep-blue perovskite-based LEDs. By spin-coating an organic halide salts solution to treat blue perovskites, the halide-exchange process leads to homogeneous mixed-halide perovskites. Introduction of multifunctional organic ammonium halide salts further reduces trap density and improves the quality of deep-blue perovskites.
ADVANCED MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Jingxuan Bi, Zhuzhu Du, Jinmeng Sun, Yuhang Liu, Ke Wang, Hongfang Du, Wei Ai, Wei Huang
Summary: Graphene is recognized as a potential anode for next-generation lithium-ion batteries (LIBs), and considerable breakthroughs have been achieved in the past decade. This review provides a research roadmap of graphene anodes toward practical LIBs, summarizing the Li storage mechanism and approaches to improve electrochemical performance. Different structural modifications, surface modifications, derivative materials, and binder-free electrodes are discussed, highlighting the advantages and prospects of graphene anodes for advanced LIBs. Remaining challenges and future opportunities are also highlighted.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
He Shao, Yueqing Li, Wei Yang, Xiang He, Le Wang, Jingwei Fu, Mingyang Fu, Haifeng Ling, Paschalis Gkoupidenis, Feng Yan, Linghai Xie, Wei Huang
Summary: A phototransistor memory based on air-stable Zr-CsPbI3 perovskite nanocrystals (PNCs) is designed, with broadband photoresponse capability. By utilizing the different electron capture ability of Zr-CsPbI3 PNCs to 650 and 405 nm light, an artificial synapse and non-volatile memory can be created on-demand and quickly reconfigured within a single device for specific purposes. The optically reconfigurable and wavelength-aware operation between short-term plasticity (STP) and long-term plasticity (LTP) modes enables integrated blue feature extraction and target recognition in a homogeneous neuromorphic vision sensor array.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
You Ke, Jingshu Guo, Decheng Kong, Jingmin Wang, Gunnar Kusch, Chen Lin, Dawei Liu, Zhiyuan Kuang, Dongmin Qian, Fuyi Zhou, Guangbin Zhang, Meiling Niu, Yu Cao, Rachel A. Oliver, Daoxin Dai, Yizheng Jin, Nana Wang, Wei Huang, Jianpu Wang
Summary: Bright and efficient deep-red LEDs are crucial for medical therapy and biological imaging. However, achieving high brightness deep-red perovskite-based LEDs has been a challenge. This study demonstrates a lateral Cs4PbI6/FA(x)Cs(1-)(x)PbI(3) (0D/3D) heterostructure that enables highly efficient deep-red perovskite LEDs. These LEDs exhibit a peak external quantum efficiency of 21.0% at a significantly higher photon flux than previously reported.
ADVANCED MATERIALS
(2023)
Article
Electrochemistry
Hehuan Xia, Daili Xiang, Fushan Liu, Liu Gong, Leichen Wang, Jialei Du, Hong Liu
Summary: Both anode feedstock and integrated electrodes are important for the development of hybrid water electrolysis technology. In this study, biomass-derived furfuryl alcohol is selected as the anode feedstock, while Cu2Co(OH)x/NF is designed as the integrated electrode. The Cu2Co(OH)x/NF electrode exhibits enhanced hydrogen production and electrocatalytic furfuryl alcohol oxidation to value-added furoic acid in alkaline conditions.
ELECTROCHIMICA ACTA
(2023)
Review
Chemistry, Physical
Xiaoming Hu, Fengwei Sun, Caijun Zhu, Zhen Yang, Wei Huang
Summary: Optical imaging has significant implications in early disease diagnosis, timely treatment, and medical and biological research. The emerging NIR-II window optical imaging technology provides non-invasive, non-ionizing radiation, and real-time dynamic imaging capabilities, with improved tissue penetration and detection sensitivity, enabling accurate diagnosis of major diseases. This review highlights the use of organic semiconducting nanomaterials (OSNs) for NIR-II fluorescence imaging, emphasizing their advantages in visualizing various diseases and outlining their potential for clinical translation.
Article
Chemistry, Physical
Runkai Lv, Zhengzheng Qian, Xiaopeng Zhao, Fei Xiong, Yingjie Xu, Wenpei Fan, Xikuang Yao, Wei Huang
Summary: Polymer-induced self-assembly is a powerful strategy for fabricating stimuli-responsive drug delivery nanosystems. In this study, a series of block copolymers were designed and synthesized, and their self-assembly behavior with gold nanoparticles was investigated. The preparation of a near-infrared light-responsive gold nanovesicle was optimized, which efficiently encapsulated an anticancer drug and prevented premature leakage. Upon laser irradiation, the loaded drug was rapidly released, leading to superior antitumor efficacy in a tumor model.
Review
Chemistry, Multidisciplinary
Guangcun Shan, Haoyi Tan, Ruguang Ma, Hongbin Zhao, Wei Huang
Summary: This review provides an overview of recent theoretical and experimental research on silicene, a two-dimensional material with distinct structures and properties. It discusses the growth and characterization of silicene on different substrates and its applications in nanoelectronics, sensors, energy storage devices, electrode materials, and quantum technology. The review also concludes with remarks on the future prospects of silicene.
Article
Chemistry, Multidisciplinary
Yingying Zheng, Mengyuan Li, Ninging Yu, Shengjie Wang, Lili Sun, Xiang An, Yamin Han, Jinyi Lin, Xuehua Ding, Wei Huang
Summary: This study confirms that the defect structure in organic optoelectronic materials is detrimental to the performance and stability of deep-blue OLEDs. It also reveals that unsaturated aromatic units are easily attacked by external influences to form organic radicals, leading to a decrease in LED efficiency. The suppression of organic radicals can improve the performance and stability of OLEDs.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Analytical
Jingjing Shen, Guan Liu, Wen Zhang, Wenwen Shi, Yang Zhou, Zejie Yu, Qunbo Mei, Lei Zhang, Wei Huang
Summary: As a crucial parameter in biochemical analysis, the pH value plays an essential role in cell function, food preservation and production, as well as soil and water sources. Therefore, it is increasingly important to explore pH detection methods. This paper introduces a pH-responsive SERS probe using a cyano Raman tag, which can detect pH values based on the displacement of the cyano Raman peak. The cyano Raman tag exhibits excellent sensitivity within the pH range of 3.0-9.0, with a limit of detection of pH 0.33, and shows anti-interference performance and stability (the relative standard deviation is calculated to be 6.68%, n = 5). These results suggest that this pH SERS probe with the Raman cyano tag could open up new research directions in biological detection, bioimaging, and environmental detection.
Article
Materials Science, Multidisciplinary
Cheng Qi, Wen-Han Wang, Jin-Fan Zheng, Li-Wen Jiang, Chao Meng, Hong Liu, Jian-Jun Wang
Summary: The recent development of nanocatalysis holds promise for cancer therapy, particularly in the form of efficient nanozymes for catalytic reactions. In this study, we synthesized ultra-small FeOx nanozymes by introducing Cu2+. These nanozymes exhibited versatile catalytic activities for effective cancer treatment, including pH-dependent peroxidase-like activity, glutathione depletion, and decomposition of hydrogen peroxide. The FeOx nanozymes also showed remarkable stability and maintained enzymatic activity after six months of storage, highlighting their potential as an effective nanomedicine for tumor treatment.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Chemistry, Physical
Yunrui Han, Yingkuan Han, Qihang He, Hong Liu, Yu Zhang, Lin Han
Summary: This study successfully fabricated an AgNPs@ LIG SERS chip with excellent sensitivity and uniformity, which realized large-scale production with controllable shape and area. The chip features a limit of detection (LOD) of 10-14 M, an enhancement factor (EF) of 3 x 1010, and fine uniformity. Furthermore, the chip was applied to the detection of melamine and showed potential application value for pollutant analysis. The preparation of the composite SERS chip is simple for mass production, providing great potential for the development of ultrasensitive SERS biosensors for various biological and chemical analyses.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Multidisciplinary
Shao-Yu Yuan, Li -Wen Jiang, Jin-Song Hu, Hong Liu, Jian-Jun Wang
Summary: In this article, we report an effective strategy for implanting fully dispersed iridium-oxide atomic clusters onto hematite, which significantly improves the photoelectrochemical water oxidation in acidic solution. The resulting photoanode achieves a record-high photocurrent of 1.35 mA cm-2 at 1.23 V, demonstrating the merits of high atomic utilization of Ir.
Article
Chemistry, Multidisciplinary
Yufu Tang, Yuanyuan Li, Zhen Wang, Wei Huang, Quli Fan, Bin Liu
Summary: Understanding the pathogenesis of nitric oxide (NO) in SARS-CoV-2 infection is crucial for preventing the spread of COVID-19 and its impact on health. The development of an activatable near-infrared-II fluorescent molecular nanoprobe allows for in situ and noninvasive visualization of NO fluctuation in lung tissues, revealing a positive relationship between NO levels and the progress of SARS-CoV-2 infection.
