Article
Clinical Neurology
Yanyuan Dai, Baixin Chen, Le Chen, Alexandros N. Vgontzas, Julio Fernandez-Mendoza, Maria Karataraki, Xiangdong Tang, Yun Li
Summary: This study found an association between insomnia with objective short sleep duration and hypertension. Short sleep duration in patients with chronic insomnia disorder was associated with a higher risk of hypertension. Additionally, for every hour decrease in total sleep time, there was a slight increase in systolic and diastolic blood pressure in patients with chronic insomnia disorder.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Peripheral Vascular Disease
Shahab Haghayegh, Susanne Strohmaier, Rikuta Hamaya, A. Heather Eliassen, Walter C. Willett, Eric B. Rimm, Eva S. Schernhammer
Summary: This study found that difficulty falling or staying asleep and short sleep duration were associated with a higher risk of hypertension among women. Therefore, screening for poor sleep may help identify individuals at higher risk for hypertension.
Article
Clinical Neurology
Yanyuan Dai, Baixin Chen, Le Chen, Alexandros N. Vgontzas, Julio Fernandez-Mendoza, Maria Karataraki, Xiangdong Tang, Yun Li
Summary: This study investigated the association between insomnia with objective short sleep duration, subjective sleep duration, and incident hypertension in the Sleep Heart Health Study. The results showed that individuals with insomnia who slept objectively < 6 hours had a higher risk of developing hypertension compared to normal sleepers, while individuals with insomnia who slept >_ 6 hours or normal sleepers who slept < 6 hours were not associated with increased risk of incident hypertension.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2023)
Article
Medicine, General & Internal
Xiaoyu Chang, Xiaofang Chen, John S. Ji, Guojin Luo, Qiang Sun, Ningmei Zhang, Yu Guo, Pei Pei, Liming Li, Zhengming Chen, Xianping Wu
Summary: This study examined the association between sleep duration and hypertension in rural adults in southwest China. The results showed that long sleep duration was significantly associated with hypertension, and a J-shaped pattern was observed. However, there was no clear association between short sleep duration and hypertension.
Review
Peripheral Vascular Disease
Nour Makarem, Carmela Alcantara, Natasha Williams, Natalie A. Bello, Marwah Abdalla
Summary: Recent literature has shown an association between short sleep duration, shift work, and obstructive sleep apnea with hypertension risk and blood pressure levels, with shift work potentially exacerbating the effects of short sleep on blood pressure. Continuous positive airway pressure treatment may improve blood pressure control in patients with hypertension. Efforts in educating patients and healthcare providers on the importance of identifying and treating sleep disturbances for hypertension prevention and management are crucial for advancing this research area.
Article
Peripheral Vascular Disease
Chooza Moon, Erika W. Hagen, Heather M. Johnson, Roger L. Brown, Paul E. Peppard
Summary: The study found that hypertension is associated with changes in sleep quality over time. Hypertensive individuals experienced a greater decline in total sleep time in rapid eye movement sleep and had less decline in N3 sleep compared to non-hypertensive individuals. They also had a higher probability of having difficulties falling asleep, as indicated by subjective insomnia complaints.
JOURNAL OF HYPERTENSION
(2021)
Article
Medicine, General & Internal
Justyna Kanclerska, Mieszko Wieckiewicz, Rafal Poreba, Anna Szymanska-Chabowska, Pawel Gac, Anna Wojakowska, Weronika Frosztega, Monika Michalek-Zrabkowska, Grzegorz Mazur, Helena Martynowicz
Summary: Sleep bruxism is more intense among patients with arterial hypertension, leading to altered sleep architecture and decreased oxygen saturation. Dental screening is necessary for patients with arterial hypertension, especially those presenting with symptoms of sleep bruxism.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Peripheral Vascular Disease
Min Ru Chee, Jesse Hoo, Renata Libianto, Stella M. Gwini, Garun Hamilton, Om Narayan, Morag J. Young, Peter J. Fuller, Jun Yang
Summary: This study found a high prevalence of possible or likely primary aldosteronism among patients with both obstructive sleep apnea and hypertension, suggesting that they should be routinely screened for PA. No correlation was found between aldosterone, renin, or aldosterone:renin ratio and the apnea-hypopnea index, indicating the need for further research on the relationship between these conditions.
Article
Pediatrics
Katelyn Seither, Benjamin M. Helm, Christine Heubi, Daniel Swarr, Kristen R. Suhrie
Summary: This study aimed to evaluate the use of PSG in children with DS aged 0-7 years, assess the prevalence and severity of OSA, and describe interventions used for OSA. The study found an inverse relationship between age and OSA severity in DS children. After intervention, 73% of patients experienced resolution or improvement of OSA.
Article
Chemistry, Analytical
Iqram Hussain, Md Azam Hossain, Rafsan Jany, Md Abdul Bari, Musfik Uddin, Abu Raihan Mostafa Kamal, Yunseo Ku, Jik-Soo Kim
Summary: Electroencephalography (EEG) is a computing tool for understanding the association between neurological outcomes and sleep stages. By analyzing sleep EEG data, neurological EEG-biomarkers can be quantified and different sleep stages can be predicted.
Article
Clinical Neurology
Ning Xia, Hao Wang, Yu Chen, Xiao-Jun Fan, Xiu-Hong Nie
Summary: This study aimed to explore the relationship between sleep efficiency (SE) and the prevalence of hypertension in Chinese obstructive sleep apnea (OSA) patients. The results showed that OSA patients with low SE were more likely to have hypertension, especially in female, younger ages, obese, moderate and severe OSA patients, compared to primary snorers.
NATURE AND SCIENCE OF SLEEP
(2023)
Article
Biochemistry & Molecular Biology
Justyna Kanclerska, Mieszko Wieckiewicz, Anna Szymanska-Chabowska, Rafal Poreba, Pawel Gac, Anna Wojakowska, Grzegorz Mazur, Helena Martynowicz
Summary: This study aimed to evaluate the plasma concentration of electrolytes and their impact on the intensity of sleep bruxism (SB) and blood pressure variability. The results showed a lower plasma sodium concentration in patients with SB, which was associated with increased blood pressure variability.
Review
Clinical Neurology
Keith A. Johnson, Christopher J. Gordon, Julia L. Chapman, Camilla M. Hoyos, Nathaniel S. Marshall, Christopher B. Miller, Ronald R. Grunstein
Summary: Insomnia disorder with objective short sleep duration is associated with a higher risk of hypertension and type 2 diabetes compared to normal sleep duration, but not with body mass index. There was no significant difference in risk between insomnia disorder with objective short sleep and objective short sleep without insomnia disorder. More cohort study data is needed to further investigate these associations.
SLEEP MEDICINE REVIEWS
(2021)
Editorial Material
Medicine, General & Internal
Scott Hoff, Nancy Collop
Summary: A 50-year-old patient with epilepsy, hypertension, loud snoring, recent 50-lb weight gain, and abrupt awakenings with a feeling of breathlessness but no headaches or excessive daytime sleepiness presented with concerns. What would you do next?
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Neurosciences
Di Zhang, Jinbo Sun, Yichong She, Yapeng Cui, Xiao Zeng, Liming Lu, Chunzhi Tang, Nenggui Xu, Badong Chen, Wei Qin
Summary: This study develops a neural network model that combines an attention-based convolutional neural network and a classifier with two branches to achieve automatic sleep staging. The model achieves expert-level accuracy in classifying stage N1, which significantly impacts the diagnosis of sleep disorders.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Psychology, Clinical
Delainey L. Wescott, Peter L. Franzen, Brant P. Hasler, Megan A. Miller, Adriane M. Soehner, Stephen F. Smagula, Meredith L. Wallace, Martica H. Hall, Kathryn A. Roecklein
Summary: This study aims to clarify the nature and extent of hypersomnolence in seasonal affective disorder (SAD) using multiple measurements. The results suggest that hypersomnolence is not a poor characterization of SAD, and self-reported hypersomnia captures multiple sleep disruptions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Biology
Marie Tuft, Martica H. Hall, Robert T. Krafty
Summary: This article introduces a new approach to time-frequency analysis that decomposes the time-varying power spectrum into orthogonal rank-one layers in time and frequency. This provides a parsimonious representation that illustrates relationships between power at different times and frequencies.
Article
Clinical Neurology
Diego R. Mazzotti, Melissa A. Haendel, Julie A. McMurry, Connor J. Smith, Daniel J. Buysse, Till Roenneberg, Thomas Penzel, Shaun Purcell, Susan Redline, Ying Zhang, Kathleen R. Merikangas, Joseph P. Menetski, Janet Mullington, Eilis Boudreau
Summary: The increasing availability and complexity of sleep and circadian data present both opportunities and challenges for the field. Improving data sharing and interoperability is crucial for advancing clinical research and requires collaboration and innovation between the sleep and informatics communities.
Letter
Clinical Neurology
Stephen F. Smagula, Sarah T. Stahl, Robert T. Krafty, Daniel J. Buysse
Article
Psychology, Developmental
Adriane M. Soehner, Rebecca A. Hayes, Peter L. Franzen, Tina R. Goldstein, Brant P. Hasler, Daniel J. Buysse, Greg J. Siegle, Ronald E. Dahl, Erika E. Forbes, Cecile D. Ladouceur, Dana L. McMakin, Neal D. Ryan, Jennifer S. Silk, Maria Jalbrzikowski
Summary: This study aimed to investigate whether interindividual differences in naturalistic sleep patterns are correlated with deviations from typical brain aging. The results showed that later sleep timing was associated with more advanced brain aging, but sleep duration, continuity, and regularity were not significantly associated with brain age gap. Gender and age did not moderate the relationship between sleep and brain age gap. Additionally, depression severity was not associated with brain age gap or sleep in this psychiatrically healthy sample.
JOURNAL OF ADOLESCENT HEALTH
(2023)
Article
Medicine, Research & Experimental
Joseph Kazan, Thandi Lyew, Emilee Croswell, Daniel J. Buysse, Marie Anne Gebara, Jordan F. Karp, Robert T. Krafty, Ammar A. Rashied, Charles F. Reynolds, Bruce L. Rollman, Stephen F. Smagula, Sarah T. Stahl
Summary: This study provides the rationale and methodology for interventions targeting sleep and depression symptoms in older widowed adults. By comparing the efficacy of a digital health intervention with enhanced usual care, the study aims to inform the development of technology-based interventions for community-based bereaved spouses.
CONTEMPORARY CLINICAL TRIALS
(2023)
Editorial Material
Psychology, Developmental
Alice M. Gregory, Martin K. Rutter, Juan J. Madrid-Valero, Sophie D. Bennett, Roz Shafran, Daniel J. Buysse
Summary: There is a need to balance standardization and personalization in therapies for mental health difficulties in young people. This editorial discusses the challenges and highlights the importance of finding the sweet spot between the two approaches, using examples of insomnia in adolescents/young adults and type 1 diabetes.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Clinical Neurology
Leslie M. Swanson, Michelle M. Hood, Martica H. Hall, Nancy E. Avis, Hadine Joffe, Alicia Colvin, Kristine Ruppert, Howard M. Kravitz, Genevieve Neal-Perry, Carol A. Derby, Rachel Hess, Sioban D. Harlow
Summary: Examining actigraphy-assessed sleep timing and regularity in early late life women, this study found that sleep timing outside of the 2:00-4:00 AM range and sleep irregularity were associated with psychological health issues.
Article
Obstetrics & Gynecology
Roxanna M. Twedt, Daniel J. Buysse, Peter L. Franzen, Megan E. Hamm, Francesca L. Facco
Summary: A sleep education program specific to pregnancy for patients with gestational diabetes mellitus was developed and tested. The study showed the feasibility of this intervention in typical care but did not demonstrate any improvement in sleep knowledge or glycemic control during pregnancy.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Clinical Neurology
Brant P. Hasler, Meredith L. Wallace, Jessica L. Graves, Rachel Witt, Kathryn Guo, Daniel J. Buysse, Greg J. Siegle, Duncan B. Clark
Summary: Later circadian timing during adolescence is associated with worse sleep, more severe depression, and greater alcohol involvement. The COVID-19 pandemic provided an opportunity to examine whether adolescents with later circadian timing showed improvements in sleep, depression, and alcohol use. Results showed that individuals with later circadian timing reported less sleep and experienced greater increases in alcohol use during the pandemic.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Ashlyn Runk, H. Matthew Lehrer, Meryl A. Butters, Daniel J. Buysse, Marissa A. Evans, Robert T. Krafty, Martica H. Hall
Summary: This study compared neurocognitive function between retired night shift workers and retired day workers, finding that retired night shift workers performed poorer on attention and executive function, suggesting an increased risk for future dementia.
Article
Medicine, General & Internal
Julien Coelho, Jacques Taillard, Adele Bernard, Regis Lopez, Guillaume Fond, Laurent Boyer, Guillaume Lucas, Francois Alla, Daniel J. Buysse, Meredith L. Wallace, Catherine Verdun-Esquer, Pierre-Alexis Geoffroy, Emmanuel d'Incau, Pierre Philip, Jean-Arthur Micoulaud-Franchi
Summary: This study investigated good sleep health among healthcare workers and its relationship with burnout. The results showed that good sleep health was associated with a reduced risk of burnout among healthcare workers.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Marquis S. Hawkins, Rachel K. Conlon, Shannon Donofry, Daniel J. Buysse, Elizabeth M. Venditti, Yu Cheng, Michele D. Levine
Summary: This study found that sleep can modify the relationship between physical activity change from the 2nd to 3rd trimester and excessive gestational weight gain. Increasing physical activity while maintaining good sleep quality, sleep efficiency, and daytime function is key to reducing excessive gestational weight gain.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Meeting Abstract
Clinical Neurology
Brant Hasler, Meredith Wallace, Jessica Graves, Daniel Buysse, Greg Siegle, Duncan Clark
Meeting Abstract
Clinical Neurology
Meredith Wallace, Soomi Lee, Katie Stone, Martica Hall, Stephen Smagula, Susan Redline, Kristine Ensrud, Sonia Ancoli-Israel, Daniel Buysse
Article
Clinical Neurology
Melanie Strauss, Lucie Griffon, Maxime Elbaz, Isabelle Arnulf, Mounir Chennaoui, Damien Leger
Summary: This study examines decision-making impairments in individuals with central disorders of hypersomnolence (CDH), specifically narcolepsy type 1 (NT1). The results suggest that both NT1 and other CDH patients have decreased learning abilities to avoid losses, which is associated with alterations in vigilance. The study provides new insights into the nature of decision-making impairments in CDH and suggests the potential for minimizing these alterations by restoring adequate vigilance.
Article
Clinical Neurology
Kyriakos Dimitriadis, Christina Stathakopoulou, Nikolaos Pyrpyris, Eirini Beneki, Elena Adamopoulou, Stergios Soulaidopoulos, Ioannis Leontsinis, Alexandros Kasiakogias, Aggelos Papanikolaou, Panagiotis Tsioufis, Konstantinos Aznaouridis, Dimitris Tsiachris, Konstantina Aggeli, Konstantinos Tsioufis
Summary: This review provides a comprehensive analysis of the common pathophysiology between sleep disordered breathing (SDB) and mitral regurgitation (MR), and discusses the effects of SDB treatment on MR and the effects of mitral valve surgery or transcatheter repair on obstructive and central sleep apnea (OSA and CSA).
Article
Clinical Neurology
Szu-Yu Hou, Ching-Ju Chiu, Jeanne Laraine Shea, Chih-Liang Wang, Hsiao-Han Tang, Po-Ching Kuo, Yi-Chieh Yang, Chih-Hsing Wu
Summary: The study aimed to examine the effects of age, menopausal status, and symptoms on sleep patterns and circadian rhythms in midlife women. Premenopausal women had the most unstable day-to-day rhythms, and women with more severe symptoms experienced greater sleep problems. Psychological symptoms were the strongest predictors for all sleep parameters.
Article
Clinical Neurology
Ya-Wen Hsiao, Wei-Lun Lin, Yu-Hui Chou, Shin-Huei Liu, Ting-Wei Ernie Liao, Shih-Ann Chen, Li-Wei Lo
Summary: This study aimed to investigate the effects of RDN on heart inflammation associated with COSA. The results suggest that RDN treatment may prevent COSA-associated heart inflammation through the JAK2-STAT3 signaling pathway.
Article
Clinical Neurology
Amy C. Reynolds, Kelly A. Loffler, Nicole Grivell, Brandon W. J. Brown, Robert J. Adams
Summary: This study aimed to understand the experience of sleep disorder diagnosis and treatment in shift workers and propose patient-informed solutions to improve access to health services. The findings showed that there were varied experiences with diagnosis and management, often taking a long time to seek help from healthcare providers after noticing symptoms. The study also identified the need for education and awareness initiatives, convenient screening and referral pathways, and tailored models of care.
Article
Clinical Neurology
Hsi -Chung Chen, Nai-Wei Hsu, Ching-Heng Lin
Summary: This study found a relationship between daytime sleepiness and mortality risk among older adults. The moderating effects of sex and physical function were examined. Specifically, the passive factor predicted mortality risk in women with good muscle power, while the active factor predicted mortality risk in men with good muscle power.
Article
Clinical Neurology
Sean P. A. Drummond, Bei Bei
Summary: This study proposes a parsimonious two-stage model for defining stages of Cognitive Behavioural Therapy for Insomnia (CBT-I) based on Sleep Restriction Therapy (SRT). Using data from a randomized clinical trial, the model helps identify patterns of treatment progression and their association with baseline insomnia severity. The model holds potential for further research on various CBT-I processes that are currently not fully understood.
Article
Clinical Neurology
Janet Jezkova, Karel Sonka, Jakub Kreisinger, Petra Prochazkova, Helena Tlaskalova-Hogenova, Sona Nevsimalova, Jitka Buskova, Radana Merkova, Tereza Dvorakova, Iva Prihodova, Simona Dostalova, Radka Roubalova
Summary: In recent years, there has been a growing interest in the influence of gut microbiota on sleep physiology. The gut microbiota affects the central nervous system and circadian rhythms, and can be associated with sleep disorders. This study observed the gut microbiota composition of patients with different types of narcolepsy and idiopathic hypersomnia, and found changes in beta diversity in these patient groups compared to healthy controls. However, after adjusting for confounding factors, the differences were no longer statistically significant. The study suggests that using metabolomics and proteomics approaches to study the role of microbiota in sleep disorders may be beneficial.
Article
Clinical Neurology
Mauro Manconi, Linda C. van der Gaag, Francesca Mangili, Corrado Garbazza, Silvia Riccardi, Christian Cajochen, Susanna Mondini, Francesca Furia, Elena Zambrelli, Simone Baiardi, Alessandra Giordano, Nicola Rizzo, Cristina Fonti, Elsa Viora, Armando D'Agostino, Alessandro Cicolin, Fabio Cirignotta, Daniele Aquilino, Alessandra Barassi, Renata del Giudice, Giulia Fior, Orsola Gambini, Barbara Giordano, Alma Martini, Chiara Serrati, Rossana Stefanelli, Silvio Scarone, Mariapaola Canevini, Valentina Fanti, Hans-Christian Stein, Anna Maria Marconi, Erica Raimondo, Emanuela Viglietta, Rossella Santoro, Giuliana Simonazzi, Alessandra Bianconcini, Francesco Meani, Nicoletta Piazza, Filippos Filippakos, Thomas Gyr
Summary: The Life-ON study provides the largest polysomnographic dataset coupled with longitudinal subjective assessments of sleep quality in pregnant women to date. Sleep disorders are highly frequent and distributed differently during pregnancy and postpartum. Routine assessment of sleep disturbances in the perinatal period is necessary to improve early detection and clinical management.
Article
Clinical Neurology
Zhihua Huang, Anqi Duan, Zhihui Zhao, Qing Zhao, Yi Zhang, Xin Li, Sicheng Zhang, Luyang Gao, Chenhong An, Qin Luo, Zhihong Liu
Summary: This study aims to investigate pulmonary arterial hypertension (PAH) phenotypes and their prognostic implications by clustering overnight cardiorespiratory signals in PAH patients. Three distinct clusters were identified, with patients in Cluster 3 exhibiting worse clinical outcomes. The presence of nocturnal hypoxemia and obstructive sleep apnea (OSA) in PAH patients was associated with increased risk of clinical worsening. Tailored management strategies addressing both PAH and nocturnal hypoxemia may improve clinical outcomes.
Article
Clinical Neurology
Yudan Lv, Yujun Wen, Ramalingam Vetrivelan, Jun Lu
Summary: This study demonstrated that the projections from the pontine parabrachial nucleus (PB) to the basal forebrain (BF) and medial septum (MS) can activate the cerebral cortex and hippocampus, providing important insights into the activities of these brain regions during the sleep-wake cycle.
Article
Clinical Neurology
Annika M. Myers, Megan E. Rech, Bengi Baran, Cara Palmer, Dimitrios Mylonas, Candice A. Alfano
Summary: This study found that N2 sleep spindles are associated with emotional functioning in school-aged children. Higher spindle density is related to decreased state-based emotional arousal towards negative affective images, and higher spindle peak frequency is associated with greater use of the positive emotion regulatory strategy of savoring.
Article
Clinical Neurology
Hung Youl Seok, Yong Won Cho
Summary: This study investigated the long-term impact of dopamine agonist treatment on altered central sensory processing in restless legs syndrome (RLS) patients. The results showed that dopamine agonist treatment effectively reduced RLS symptoms but did not reverse the altered central sensory processing observed on testing. These findings suggest that RLS pathophysiology is multifactorial and not solely driven by dopaminergic dysfunction.