期刊
SLEEP MEDICINE
卷 12, 期 10, 页码 997-1002出版社
ELSEVIER
DOI: 10.1016/j.sleep.2011.05.009
关键词
Sleep; Adolescence; Inflammation; Endothelial function; C-reactive protein; Physical activity
资金
- Spanish Ministry of Education and Science [DEP2006-56184-C03-02/PREV, AP2006-02464]
- European Union
Objective: To examine the associations between sleep duration and emerging inflammatory and endothelial function risk factors in adolescents. Methods: This study included a total of 183 (88 girls) adolescents, aged 13-17 years, without diagnosed sleep-related disorders. White blood cell counts, C-reactive protein (CRP), complement factors 3 and 4, interleukin-6, adiponectin, leptin, inter-cellular adhesion molecule 1, vascular cell adhesion molecule-1, E-selectin, L-selectin, and plasminogen activator inhibitor-1 were measured. Sleep duration and sleep-related disorders were obtained by self-report and moderate-to-vigorous physical activity (MVPA) was objectively measured by accelerometer. Body mass index (BMI) was calculated from measured height and weight. Results: A significant inverse association between sleep duration and CRP (beta = -0.17, P = 0.024) existed only after controlling for sex, age, and pubertal status. The results did not change when MVPA was included into the model. However, the association of sleep duration with CRP was slightly attenuated when BMI was included in the model, though it remained significant (beta = -0.15, P = 0.044). Conclusion: Short sleep duration during adolescence might play an important and independent role in cardiovascular and metabolic diseases through CRP. (C) 2011 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据