Early severe impairment of hematopoietic stem and progenitor cells from the bone marrow caused by CLP sepsis and endotoxemia in a humanized mice model

Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis

(2014) S. Boettcher et al.   BLOOD

Conversion of Danger Signals into Cytokine Signals by Hematopoietic Stem and Progenitor Cells for Regulation of Stress-Induced Hematopoiesis

(2014) Jimmy L. Zhao et al.   Cell Stem Cell

Delayed emergency myelopoiesis following polymicrobial sepsis in neonates

(2014) Alex G Cuenca et al.   Innate Immunity

Abandon the Mouse Research Ship? Not Just Yet!

(2014) Marcin F. Osuchowski et al.   SHOCK

Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs

(2013) Borhane Guezguez et al.   Cell Stem Cell

Monitoring cell proliferation in vitro with different cellular fluorescent dyes

(2013) Joanna Zolnierowicz et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Animal models of sepsis

(2013) Mitchell P Fink   Virulence

Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling

(2012) S. Bugl et al.   BLOOD

Development of Mature and Functional Human Myeloid Subsets in Hematopoietic Stem Cell-Engrafted NOD/SCID/IL2r KO Mice

(2012) S. Tanaka et al.   JOURNAL OF IMMUNOLOGY

Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study

(2012) Mitchell M Levy et al.   LANCET INFECTIOUS DISEASES

Effect of Acute Lung Injury on VLA-4 and CXCR4 Expression in Resident and Circulating Hematopoietic Stem/Progenitor Cells

(2012) Teresa Trotta et al.   RESPIRATION

The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury

(2011) Mitsuhiro Yamada et al.   Cellular & Molecular Immunology

Neutrophil Mobilization from the Bone Marrow during Polymicrobial Sepsis Is Dependent on CXCL12 Signaling

(2011) M. J. Delano et al.   JOURNAL OF IMMUNOLOGY

Chronic Exposure to a TLR Ligand Injures Hematopoietic Stem Cells

(2011) B. L. Esplin et al.   JOURNAL OF IMMUNOLOGY

LPS-Induced Migration of Peritoneal B-1 Cells is Associated with Upregulation of CXCR4 and Increased Migratory Sensitivity to CXCL12

(2011) Hana Moon et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

STAT3 controls myeloid progenitor growth during emergency granulopoiesis

(2010) H. Zhang et al.   BLOOD

Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation

(2010) Andreia Soares et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cutting Edge: Bacterial Infection Induces Hematopoietic Stem and Progenitor Cell Expansion in the Absence of TLR Signaling

(2010) Philip O. Scumpia et al.   JOURNAL OF IMMUNOLOGY

Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex

(2010) M Z Ratajczak et al.   LEUKEMIA

Macroscopic Postmortem Findings in 235 Surgical Intensive Care Patients with Sepsis

(2009) Christian Torgersen et al.   ANESTHESIA AND ANALGESIA

Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis

(2009) S. Rodriguez et al.   BLOOD

The hematopoietic stem cell niche: Low in oxygen but a nice place to be

(2009) Pernilla Eliasson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sepsis-induced human lymphocyte apoptosis and cytokine production in “humanized” mice

(2009) Jacqueline Unsinger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

(2009) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Lineage−c-Kit+Sca-1+ Cell Response toEscherichia coliBacteremia in Balb/c Mice

(2008) Ping Zhang et al.   STEM CELLS

Busulfan Produces Efficient Human Cell Engraftment in NOD/LtSz-Scid IL2RγNullMice

(2008) Jun Hayakawa et al.   STEM CELLS

Short-Term Culture of Umbilical Cord Blood–Derived CD34 Cells Enhances Engraftment Into NOD/SCID Mice Through Increased CXCR4 Expression

(2008) Norioki Ohno et al.   STEM CELLS AND DEVELOPMENT