Targeting the Nuclear Export Protein XPO1/CRM1 Reverses Epithelial to Mesenchymal Transition
出版年份 2015 全文链接
标题
Targeting the Nuclear Export Protein XPO1/CRM1 Reverses Epithelial to Mesenchymal Transition
作者
关键词
-
出版物
Scientific Reports
Volume 5, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-11-05
DOI
10.1038/srep16077
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia
- (2015) Z. A. Hing et al. BLOOD
- Decitabine priming enhances the antileukemic effects of exportin 1 (XPO1) selective inhibitor selinexor in acute myeloid leukemia
- (2015) P. Ranganathan et al. BLOOD
- Identifying Drug-Target Selectivity of Small-Molecule CRM1/XPO1 Inhibitors by CRISPR/Cas9 Genome Editing
- (2015) Jasper E. Neggers et al. CHEMISTRY & BIOLOGY
- Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice
- (2015) J Etchin et al. LEUKEMIA
- Nuclear retention of Fbw7 by specific inhibitors of nuclear export leads to Notch1 degradation in pancreatic cancer
- (2015) Jiankun Gao et al. Oncotarget
- YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin
- (2015) Mohammad Imran Khan et al. Oncotarget
- Selective inhibitors of nuclear export (SINE) as novel therapeutics for prostate cancer
- (2015) Janet Mendonca et al. Oncotarget
- LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins
- (2014) Darui Xu et al. BIOINFORMATICS
- PKD1 Phosphorylation-Dependent Degradation of SNAIL by SCF-FBXO11 Regulates Epithelial-Mesenchymal Transition and Metastasis
- (2014) Hanqiu Zheng et al. CANCER CELL
- Deregulation of miR-146a expression in a mouse model of pancreatic cancer affecting EGFR signaling
- (2014) Shadan Ali et al. CANCER LETTERS
- Unveiling the Role of Nuclear Transport in Epithelial-to-Mesenchymal Transition
- (2014) Asfar Azmi CURRENT CANCER DRUG TARGETS
- Pancreatic Cancer Stem-like Cells Display Aggressive Behavior Mediated via Activation of FoxQ1
- (2014) Bin Bao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Snail nuclear transport: The gateways regulating epithelial-to-mesenchymal transition?
- (2014) Irfana Muqbil et al. SEMINARS IN CANCER BIOLOGY
- Clinical translation of nuclear export inhibitors in cancer
- (2014) William T. Senapedis et al. SEMINARS IN CANCER BIOLOGY
- Promising SINEs for Embargoing Nuclear-Cytoplasmic Export as an Anticancer Strategy
- (2014) D. S. P. Tan et al. Cancer Discovery
- Regulation of the protein stability of EMT transcription factors
- (2014) VM Díaz et al. Cell Adhesion & Migration
- Systems analysis reveals a transcriptional reversal of the mesenchymal phenotype induced by SNAIL-inhibitor GN-25
- (2013) Asfar S Azmi et al. BMC Systems Biology
- EMT in developmental morphogenesis
- (2013) Yukiko Nakaya et al. CANCER LETTERS
- Selective inhibitors of nuclear export for the treatment of non-Hodgkin's lymphomas
- (2013) A. S. Azmi et al. HAEMATOLOGICA
- Mechanisms and function of substrate recruitment by F-box proteins
- (2013) Jeffrey R. Skaar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability
- (2013) R. Vinas-Castells et al. NUCLEIC ACIDS RESEARCH
- Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia
- (2012) R. Lapalombella et al. BLOOD
- Selective Inhibitors of Nuclear Export Block Pancreatic Cancer Cell Proliferation and Reduce Tumor Growth in Mice
- (2012) Asfar S. Azmi et al. GASTROENTEROLOGY
- Consensus Induced Fit Docking (cIFD): methodology, validation, and application to the discovery of novel Crm1 inhibitors
- (2012) Ori Kalid et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry
- (2012) Ketan Thakar et al. MOLECULAR & CELLULAR PROTEOMICS
- NESdb: a database of NES-containing CRM1 cargoes
- (2012) Darui Xu et al. MOLECULAR BIOLOGY OF THE CELL
- Nuclear export of proteins and drug resistance in cancer
- (2011) Joel G. Turner et al. BIOCHEMICAL PHARMACOLOGY
- Snail Family Regulation and Epithelial Mesenchymal Transitions in Breast Cancer Progression
- (2010) Antonio Garcia de Herreros et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression
- (2010) Douglas S. Micalizzi et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Control of cell growth by the SCF and APC/C ubiquitin ligases
- (2009) Jeffrey R Skaar et al. CURRENT OPINION IN CELL BIOLOGY
- The Hypoxia-controlled FBXL14 Ubiquitin Ligase Targets SNAIL1 for Proteasome Degradation
- (2009) Rosa Viñas-Castells et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural basis for leucine-rich nuclear export signal recognition by CRM1
- (2009) Xiuhua Dong et al. NATURE
- Nuclear pore proteins and cancer
- (2009) Songli Xu et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
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