Article
Multidisciplinary Sciences
Maxwell G. Machani, Eric Ochomo, Fred Amimo, Wolfgang R. Mukabana, Andrew K. Githeko, Guiyun Yan, Yaw A. Afrane
Summary: Long-lasting insecticidal nets are effective in reducing malaria transmission, but it is important to understand the behavior of malaria vectors with insecticide resistance around human-occupied bed nets.
Article
Entomology
Victoria A. Ingham, Linda Grigoraki, Hilary Ranson
Summary: Pyrethroids are still the most important insecticides for controlling malaria mosquitoes. However, resistance to pyrethroids in the major African malaria vector Anopheles gambiae has greatly accelerated in the 21st century. This review summarizes the current understanding of the mechanisms underlying this resistance and the challenges in developing genetic markers for monitoring and managing insecticide resistance in malaria vectors.
ENTOMOLOGIA GENERALIS
(2023)
Article
Parasitology
Jeff Jones, Agnes Matope, Priscille Barreaux, Katherine Gleave, Keith Steen, Hilary Ranson, Philip J. Mccall, Geraldine M. Foster
Summary: The modification to the WHO cone test allows for additional mosquito behavior data, providing unique insights into the innate responses of different mosquito strains on untreated nets and the entomological mode of action of ITNs.
PARASITES & VECTORS
(2023)
Article
Multidisciplinary Sciences
Cristina Yunta, Jocelyn M. F. Ooi, Folasade Oladepo, Sofia Grafanaki, Spiros. A. Pergantis, Dimitra Tsakireli, Hanafy M. Ismail, Mark J. I. Paine
Summary: Chlorfenapyr is an increasingly used pro-insecticide in combination with pyrethroids to control pyrethroid-resistant mosquito populations. Different P450s in mosquitoes were investigated for their ability to metabolize chlorfenapyr, providing valuable insights into its metabolism and highlighting the need for further investigation into effective vector control strategies.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Priscille Barreaux, Hilary Ranson, Geraldine M. M. Foster, Philip J. J. McCall
Summary: The blood feeding behavior of female mosquitoes, which affects their ability to transmit malaria, is not well understood in the presence of insecticide-treated nets (ITNs). This study examines how both insecticide resistant and susceptible mosquitoes interact with different types of nets while attempting to blood feed on a human arm. The results showed that ITNs did not effectively prevent host searching but significantly reduced blood feeding success and volume for all mosquitoes, although the resistant mosquitoes were able to compensate for the decrease by accelerating their rate of blood ingestion.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Edmund J. Norris, Jeffrey R. Bloomquist
Summary: This study explored the potential of two sodium channel activators, veratrine and aconitine, as insecticides and synergists of natural pyrethrins on Aedes aegypti. Aconitine was more toxic than veratrine and showed significant resistance in the pyrethroid-resistant strain. When applied in mixtures with piperonyl butoxide and pyrethrins, large synergism values were observed, particularly with aconitine on the pyrethroid-susceptible strain. The alkaloids also demonstrated synergistic effects when applied directly to the mosquito larval nervous system.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2022)
Article
Infectious Diseases
Nelson Grisales, Rosemary S. Lees, James Maas, John C. Morgan, Dimitri W. Wangrawa, Wamdaogo M. Guelbeogo, Sagnon N'Fale, Steven W. Lindsay, Philip J. McCall, Hilary Ranson
Summary: This study found that exposure to a mixture of PPF and pyrethroids on netting shortens the lifespan of mosquitoes and reduces reproductive output. Sterilization of vectors lasted at least one year under operational conditions.
Article
Multidisciplinary Sciences
Seynabou Sougoufara, Hanna Yorkston-Dives, Nurul Masyirah Aklee, Adanan Che Rus, Jaal Zairi, Frederic Tripet
Summary: This study found that mosquitoes are able to associate the odor of pesticides with their detrimental effects and subsequently avoid pesticide contact. These findings highlight the importance of mosquito cognition as determinants of pesticide resistance in mosquito populations targeted by chemical control.
SCIENTIFIC REPORTS
(2022)
Article
Obstetrics & Gynecology
Joseph Kawuki, Elorm Donkor, Ghislaine Gatasi, Lilian Nuwabaine
Summary: In malaria-endemic countries like Rwanda, the usage of mosquito bed nets is crucial for malaria prevention. However, there is a lack of research on the usage of bed nets by pregnant women in Rwanda. This study found that around half of the pregnant women used bed nets, and the usage was associated with various socio-demographic factors.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Infectious Diseases
Aristide S. Hien, Dieudonne D. Soma, Samina Maiga, Dramane Coulibaly, Abdoulaye Diabate, Allison Belemvire, Mame B. Diouf, Djenam Jacob, Adama Kone, Ellen Dotson, Taiwo S. Awolola, Richard M. Oxborough, Roch K. Dabire
Summary: High intensity pyrethroid resistance in An. gambiae s.l. is widespread in Burkina Faso, prompting the need for alternative insecticide-treated nets. Bioassays showed that susceptibility to chlorfenapyr was confirmed in most sites, while resistance to pyrethroids remains a challenge despite some partial restoration of susceptibility with PBO pre-exposure.
Article
Parasitology
Cyntia-Muriel Y. Clegban, Soromane Camara, A. Alphonsine Koffi, Ludovic P. Ahoua Alou, Jean-Paul Kabran Kouame, A. Fernand Koffi, Philippe K. Kouassi, Nicolas Moiroux, Cedric Pennetier
Summary: Long-lasting insecticidal nets (LLINs) have been effective in reducing global malaria burden since 2000. In this study, two new brands of deltamethrin-impregnated nets were evaluated against wild pyrethroid-resistant mosquitoes, showing that they met WHO criteria and are suitable for further testing at the community level. With the increasing pyrethroid resistance, integrated vector management using a variety of control tools is needed for effective malaria control.
PARASITES & VECTORS
(2021)
Article
Biochemistry & Molecular Biology
Luminita Crisan, Simona Funar-Timofei, Ana Borota
Summary: This article investigates new insecticides targeting vector-borne infectious diseases, particularly malaria transmitted by mosquitoes. By constructing a 3D model of the receptor and conducting docking experiments, researchers identified possible binding sites and discovered a potential new insecticide.
Article
Parasitology
Emilie S. Ngongang-Yipmo, Magellan Tchouakui, Benjamin D. Menze, Leon M. J. Mugenzi, Flobert Njiokou, Charles S. Wondji
Summary: This study investigated the efficacy of different brands of LLINs against pyrethroid-resistant mosquitoes and their post-exposure effect. The results showed that standard bednets had reduced efficacy against resistant mosquitoes in the field, but still induced delayed mortality in exposed populations. The study also highlighted the importance of using new-generation nets that do not solely rely on pyrethroids.
PARASITES & VECTORS
(2022)
Article
Entomology
Salomon Efa, Emmanuel Elanga-Ndille, Yacouba Poumachu, Billy Tene, Jacqueline Ze Mikande, Njoumemi Zakariaou, Charles S. Wondji, Cyrille Ndo
Summary: Monitoring insecticide resistance in major malaria vectors like Anopheles gambiae s.l. is crucial for designing effective vector control strategies and preventing the spread of resistance. This study in Ebolowa, Southern Cameroon, revealed high resistance to pyrethroid insecticides in Anopheles coluzzii, posing a risk to the efficacy of Long-Lasting Insecticidal Nets (LLINs) used for malaria control. Urgent implementation of resistance management strategies is needed to maintain the effectiveness of insecticide-based interventions.
Article
Parasitology
Nadege Sonhafouo-Chiana, Leslie Diane Nkahe, Edmond Kopya, Parfait Herman Awono-Ambene, Samuel Wanji, Charles Sinclair Wondji, Christophe Antonio-Nkondjio
Summary: This study assessed the evolution of insecticide resistance and patterns of pesticide usage in agriculture in Yaounde, Cameroon. The results showed high resistance intensity to pyrethroids and uncontrolled usage of pesticides by farmers. It concluded that there is an urgent need to improve the management of insecticide resistance.
PARASITES & VECTORS
(2022)
Article
Optics
Matthew L. Hall, Philip McCall, Catherine E. Towers, David P. Towers
Summary: Using intensity gradient- or sparsity-based focus metrics for accurately localizing small objects in digital holographic reconstructions of large fields of view is challenging in the presence of multiple nearby objects. This study proposes a more accurate alternative method based on evaluating the complex reconstructed volume, which demonstrates reduced depth positional error for single objects and notably improved axial resolution for multiple objects in close proximity. Published under a Creative Commons Attribution 4.0 License by The Optical Society.
Article
Infectious Diseases
Jeff Jones, Gregory P. D. Murray, Philip J. McCall
Summary: Advances in digitized video-tracking and behavioural analysis have enabled the development of a virtual testing model that accurately simulates indoor flight behavior of host-seeking mosquitoes interacting with simulated stimuli from a human-occupied bed net.
Article
Entomology
Francine Sado Yousseu, Huguette Simo Tchetgna, Basile Kamgang, Doumani Djonabaye, Philip J. McCall, Roland Ndip Ndip, Charles S. Wondji
Summary: This study aimed to investigate the impact of ticks on livestock and humans in Cameroon. The results showed a high tick infestation rate in cattle, while it was low in small ruminants. The study also revealed a wide diversity of tick species, including some known vectors of important tick-borne diseases.
MEDICAL AND VETERINARY ENTOMOLOGY
(2022)
Article
Infectious Diseases
Audrey Lenhart, Carmen Elena Castillo, Elci Villegas, Neal Alexander, Veerle Vanlerberghe, Patrick van der Stuyft, Philip S. McCall
Summary: A large-scale trial in Venezuela found that the use of insecticide treated curtains and water jar covers can effectively control dengue vector populations, especially when used in combination.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Article
Infectious Diseases
Angela Hughes, Agnes Matope, Mischa Emery, Keith Steen, Gregory Murray, Hilary Ranson, Philip J. McCall, Geraldine M. Foster
Summary: The study used the WHO cone test to evaluate the efficacy of insecticide-treated bed nets. The results showed that there are differences between the results obtained from the test and the actual interaction between mosquitoes and nets in real-world settings. Additionally, using a host and blood feeding during the test provides a more representative estimate of the effectiveness of bed nets.
Article
Entomology
Lassane Koala, Inaki Tirados, Achille S. Nikiema, Edward Thomsen, Philip J. McCall, Roch K. Dabire
Summary: Despite ethical concerns, few alternatives to Human Landing Catches (HLC) for monitoring Simulium damnosum complex in onchocerciasis have been reported. This study tested visual targets and olfactory stimuli for their attractiveness to blackflies, and found that small sticky black targets of horizontal rectangular shape were the most efficient alternative to HLC.
MEDICAL AND VETERINARY ENTOMOLOGY
(2022)
Article
Entomology
Hyacinthe K. Toe, Soumanaba Zongo, Moussa W. Guelbeogo, Basile Kamgang, Mafalda Viana, Madou Tapsoba, Antoine Sanou, Alphonse Traore, Philip J. McCall, N'Fale Sagnon
Summary: The response to recent dengue outbreaks in Burkina Faso relied on insecticide-based measures, but the susceptibility of the vector population to the insecticides used was not well understood. This study found that Aedes aegypti populations in Burkina Faso exhibited resistance to multiple insecticide classes, indicating the importance of monitoring insecticide resistance in national dengue control programs.
MEDICAL AND VETERINARY ENTOMOLOGY
(2022)
Article
Infectious Diseases
Athanase Badolo, Aboubacar Sombie, Felix Yameogo, Dimitri W. Wangrawa, Aboubakar Sanon, Patricia M. Pignatelli, Antoine Sanon, Mafalda Viana, Hirotaka Kanuka, David Weetman, Philip J. Mccall
Summary: The emergence of dengue in West Africa, particularly the outbreaks in Burkina Faso in 2016 and 2017, has led to surveys of Aedes populations in the capital city of Ouagadougou. The results show that the abundance of adult Ae. aegypti is significantly higher in urban areas compared to the rural site, which has a higher population of Anopheles spp. The vector population is highly anthropophilic and exhibits a high proportion of bloodfed females caught inside houses. The primary larval habitats are waste tires, animal troughs, and large water barrels. Factors influencing adult and immature stage densities include rainfall, container water level, collection month, and container type/purpose.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Article
Infectious Diseases
Francine Yousseu Sado, Huguette Simo Tchetgna, Basile Kamgang, Doumani Djonabaye, Emmanuel Nakoune, Philip J. McCall, Roland Ndip Ndip, Charles S. Wondji
Summary: This study aimed to determine the seroprevalence of Rift Valley fever virus (RVFV) in domestic ruminants in two markets in Yaounde, Cameroon. The results showed a high prevalence of RVFV in livestock, indicating the circulation of the virus in Cameroon. Further epidemiological studies are needed to understand the transmission of RVFV in the country.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Article
Parasitology
Wendegoudi Mathias Ouedraogo, Kobie Hyacinthe Toe, Aboubacar Sombie, Mafalda Viana, Clarisse Bougouma, Antoine Sanon, David Weetman, Philip J. McCall, Hirotaka Kanuka, Athanase Badolo
Summary: This study investigates the characteristics and productivity of Aedes container breeding sites in Burkina Faso, shedding light on factors associated with larvae abundance and adult body size. The results suggest that targeting the most productive breeding sites could contribute to dengue vector control strategies.
PARASITES & VECTORS
(2022)
Article
Parasitology
Aboubacar Sombie, Wendegoudi Mathias Ouedraogo, Manabu Ote, Erisha Saiki, Tatsuya Sakurai, Felix Yameogo, Antoine Sanon, Philip J. McCall, Hirotaka Kanuka, David Weetman, Athanase Badolo
Summary: Since 2000, Burkina Faso has seen regular dengue cases and outbreaks, highlighting the increasing importance of dengue as a health concern in the country. Resistance to pyrethroid insecticides in Aedes aegypti mosquitoes has been linked to specific kdr mutations. This study confirms high resistance to pyrethroids in the Ae. aegypti populations and proposes a new PCR-based diagnostic method for detecting kdr mutations.
PARASITES & VECTORS
(2023)
Review
Virology
Luca Facchinelli, Athanase Badolo, Philip J. McCall
Summary: Ae. aegypti is a common mosquito vector of arboviruses in urbanized areas of the tropics and subtropics, but control of this species is difficult and costly. The literature on adult Ae. aegypti biology and behavior near human homes is lacking in important details, making it unreliable for developing control interventions. Basic information sources are poor and outdated, while commonly accepted facts lack evidence. Topics such as sugar feeding, resting preferences, and blood feeding require further research to identify vulnerabilities for control efforts in different contexts.
Article
Biology
Yasser M. Qureshi, Vitaly Voloshin, Luca Facchinelli, Philip J. McCall, Olga Chervova, Cathy E. Towers, James A. Covington, David P. Towers
Summary: This paper presents a method for identifying key behavioral differences between male, female, and in copula mosquito pairs by analyzing their flight tracks. The approach uses machine learning to classify track segments as either male or non-male and combines the segment classifications to classify the overall track. This methodology provides valuable insights into the behavior of mosquitoes and other insects.
Article
Multidisciplinary Sciences
Luca Facchinelli, Bashir Alsharif, Jeff D. Jones, Agnes Matope, Rosangela M. R. Barbosa, Constancia F. J. Ayres, Philip J. McCall
Summary: This study found that Aedes aegypti mosquitoes prefer to rest at the base of walls, especially at higher temperatures, highlighting the importance of this resting behavior for mosquito control. The researchers discovered that treating the lowest 20 cm of indoor walls with insecticide significantly reduced the mosquito population.