The “De-escalation Concept” and Antibiotic De-escalation

De-escalation of antimicrobials in the treatment of bacteraemia due to antibiotic-sensitive pathogens in immunocompetent patients

(2011) N. Shime et al.   INFECTION

Contemporary activity of colistin and polymyxin B against a worldwide collection of Gram-negative pathogens: results from the SENTRY Antimicrobial Surveillance Program (2006-09)

(2011) A. C. Gales et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Infection withKlebsiella pneumoniaecarbapenemase (KPC)-producingK. pneumoniaein solid organ transplantation

(2011) M.D. Bergamasco et al.   Transplant Infectious Disease

Practice patterns for antibiotic de-escalation in culture-negative healthcare-associated pneumonia

(2010) M. Schlueter et al.   INFECTION

Empiric, Broad-Spectrum Antibiotic Therapy with an Aggressive De-Escalation Strategy Does Not Induce Gram-Negative Pathogen Resistance in Ventilator-Associated Pneumonia

(2010) Michael L. Hibbard et al.   Surgical Infections

Does De-Escalation of Antibiotic Therapy for Ventilator-Associated Pneumonia Affect the Likelihood of Recurrent Pneumonia or Mortality in Critically Ill Surgical Patients?

(2009) Soumitra R. Eachempati et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE