Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

(2015) Eva M. Palsson-McDermott et al.   Cell Metabolism

CD73 Plays a Protective Role in Collagen-Induced Arthritis

(2015) Pavel Chrobak et al.   JOURNAL OF IMMUNOLOGY

Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis

(2015) Raphael Sanches Peres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapies for Active Rheumatoid Arthritis after Methotrexate Failure

(2013) James R. O'Dell et al.   NEW ENGLAND JOURNAL OF MEDICINE

M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation

(2013) H. P. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

Regulation of Inflammation by Adenosine

(2013) György Haskó et al.   Frontiers in Immunology

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

(2012) Dimitrios Anastasiou et al.   Nature Chemical Biology

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selective Activation of Adenosine A2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis

(2012) U. Flogel et al.   Science Translational Medicine

CGS 21680, an Agonist of the Adenosine (A2A) Receptor, Reduces Progression of Murine Type II Collagen-induced Arthritis

(2011) EMANUELA MAZZON et al.   JOURNAL OF RHEUMATOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Detrimental effects of adenosine signaling in sickle cell disease

(2010) Yujin Zhang et al.   NATURE MEDICINE

Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A1 receptors

(2009) DA Valério et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal models of rheumatoid arthritis

(2009) Darren L. Asquith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-17 mediates articular hypernociception in antigen-induced arthritis in mice

(2009) Larissa G. Pinto et al.   PAIN

CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis

(2008) Renata Grespan et al.   ARTHRITIS AND RHEUMATISM