Article
Pediatrics
Simei Wang, Quanmei Xu, Anqi Wang, Fang Yuan, Xiaona Luo, Yilin Wang, Miao Guo, Yuanfeng Zhang, Wenjing Zhang, Xiaobing Ji, Yun Ren, Yucai Chen
Summary: This study found a correlation between 25-hydroxyvitamin D deficiency and tic disorders (TD) in Chinese children, but no correlation between 25-hydroxyvitamin D deficiency and the severity of TD. Additionally, the deficiency of 25-hydroxyvitamin D was most pronounced in children over the age of 9.
FRONTIERS IN PEDIATRICS
(2022)
Review
Nutrition & Dietetics
Manuel Rupprecht, Stefan Wagenpfeil, Jakob Schoepe, Reinhold Vieth, Thomas Vogt, Joerg Reichrath
Summary: A meta-analysis was conducted to investigate the impact of oral vitamin D supplementation on serum 25-hydroxyvitamin D levels in healthy adults in Europe. The findings suggest that vitamin D supplementation can significantly increase serum 25(OH)D levels, with the effect influenced by dosage and baseline serum levels.
Article
Nutrition & Dietetics
Limin Yang, Miori Sato, Mayako Saito-Abe, Minaho Nishizato, Hidetoshi Mezawa, Kiwako Yamamoto-Hanada, Yukihiro Ohya
Summary: The study found no association between early-life 25-hydroxyvitamin D levels and the risk of developing childhood atopic dermatitis (AD).
Article
Endocrinology & Metabolism
Li Liu, Mingming Xu, Hang Zhou, Xuexue Hao, Xiangyu Chen, Xiaoqiang Liu
Summary: The study found that decreased serum 25-hydroxyvitamin D levels were associated with stress urinary incontinence and mixed urinary incontinence in elderly men.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Nutrition & Dietetics
Marcela M. Mendes, Anna P. O. Gomes, Maisa M. Araujo, Alexandre S. G. Coelho, Kenia M. B. Carvalho, Patricia B. Botelho
Summary: This review aimed to estimate the prevalence of vitamin D deficiency in South American populations. A total of 96 studies involving 227,758 participants were included. The overall prevalence of vitamin D deficiency was found to be 34.76%. Age, sex, country, latitude, season, and year of publication were factors associated with the prevalence rates. Therefore, public health strategies should address the prevention, detection, and treatment of vitamin D deficiency.
Article
Nutrition & Dietetics
Bridget A. Baxter, Michaela G. Ryan, Stephanie M. LaVergne, Sophia Stromberg, Kailey Berry, Madison Tipton, Nicole Natter, Nikiah Nudell, Kim McFann, Julie Dunn, Tracy L. Webb, Michael Armstrong, Nichole Reisdorph, Elizabeth P. Ryan
Summary: This study investigates the association between vitamin D deficiency and COVID-19 severity among survivors. The findings show a correlation between vitamin D deficiency and severe cases, as well as the presence of post-acute sequelae of COVID-19 (PASC) among survivors. Gender and BMI are also found to be related to vitamin D levels, but not to the presence of PASC.
Article
Nutrition & Dietetics
Kuo-Chuan Hung, Sheng-Hsiang Yang, Chia-Yu Chang, Li-Kai Wang, Yao-Tsung Lin, Chia-Hung Yu, Min-Hsiang Chuang, Jen-Yin Chen
Summary: A meta-analysis of 16 observational studies revealed a negative association between serum vitamin D levels and the risk of VTE. This association remained significant in subgroup analyses and in the presence of neurological diseases. Individuals with vitamin D deficiency had an increased risk of VTE compared to those with normal levels.
Review
Food Science & Technology
Zebenay Workneh Bitew, Teshager Worku, Ayinalem Alemu
Summary: Vitamin D deficiency is prevalent among neonates, especially those with sepsis. Low maternal and cord blood levels of vitamin D are significantly associated with an increased risk of neonatal sepsis. Supplementing pregnant women and newborns with vitamin D could help decrease the incidence of neonatal sepsis.
FOOD SCIENCE & NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Shufei Zeng, Chang Chu, Cornelia Doebis, Volker von Baehr, Berthold Hocher
Summary: There is a strong positive linear correlation between free 25(OH)D (f25(OH)D) and total 25(OH)D, making them useful for assessing vitamin D levels. The recommended threshold level for f25(OH)D is 8.499 pg/mL, corresponding to a target concentration of at least 30 ng/mL for t25(OH)D. The upper limit for vitamin D is still unclear, with most experts favoring a upper limit of 100 ng/mL for t25(OH)D.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2021)
Article
Nutrition & Dietetics
Guowei Li, Likang Li, Jonathan D. Adachi, Ruoting Wang, Zebing Ye, Xintong Liu, Lehana Thabane, Gregory Y. H. Lip
Summary: This study found a quasi J-shaped relationship between serum circulating 25-hydroxyvitamin D (25(OH)D) level and risk of recurrent stroke in patients with a stroke history. The lowest risk of recurrent stroke was observed at a 25(OH)D level of approximately 60 nmol/L, which was associated with a 48% reduction in risk compared to a level of 10 nmol/L.
Article
Pediatrics
Limin Yang, Miori Sato, Mayako Saito-Abe, Makoto Irahara, Minaho Nishizato, Hatoko Sasaki, Mizuho Konishi, Kazue Ishitsuka, Hidetoshi Mezawa, Kiwako Yamamoto-Hanada, Yukihiro Ohya
Summary: This study aimed to obtain epidemiological data on vitamin D levels for the pediatric population in Japan. The results showed that vitamin D deficiency and insufficiency are very common among 2-year-old Japanese children, with factors such as sex, season, and latitude affecting serum 25(OH) D concentrations.
Review
Nutrition & Dietetics
Maria Morales-Suarez-Varela, Nazli Ucar, Jose Miguel Soriano, Agustin Llopis-Morales, Beth S. Sanford, William B. Grant
Summary: Vitamin D deficiency in pregnant women is common and associated with health problems such as gestational diabetes and preeclampsia. This systematic review examines the association between 25(OH)D levels and health effects, indicating that adequate vitamin D levels play a role in reducing risk and promoting a healthy pregnancy.
Article
Nutrition & Dietetics
RuTong Wang, Weijing Wang, Ping Hu, Ronghui Zhang, Xue Dong, Dongfeng Zhang
Summary: This study aimed to evaluate the association between dietary vitamin D intake and serum vitamin D concentrations with cognitive performance in older Americans. The results showed a positive association between dietary vitamin D intake, serum total 25-hydroxyvitamin D, and cognitive performance, with no significant gender differences in the associations. Further research is needed to clarify the effects of dietary vitamin D intake and specific serum D concentrations on cognitive performance.
Article
Nutrition & Dietetics
Chung-Jen Lee, Yi-Jen Hsieh, Yu-Li Lin, Chih-Hsien Wang, Bang-Gee Hsu, Jen-Pi Tsai
Summary: This study found that lower serum 25-hydroxyvitamin D levels and older age were associated with peripheral arterial stiffness in patients with stage 3-5 chronic kidney disease.
Article
Pediatrics
Akif Mustafa, Chander Shekhar
Summary: The study reveals a high prevalence of vitamin D deficiency among children and adolescents in India, especially in certain high-risk groups. This research provides important insights for prompt policy interventions for these high-risk groups.
Article
Psychology, Clinical
Osvaldo P. Almeida, Graeme J. Hankey, Bu B. Yeap, Jonathan Golledge, Christopher Etherton-Beer, Suzanne Robinson, Leon Flicker
Summary: Cancer is associated with a lower risk of dementia, although methodological issues raise concerns about this relationship. A long-term study of 31,080 men aged 65-85 years found that the hazard ratio of dementia associated with cancer was 1.13, but dropped to 0.85 when excluding participants who developed dementia within 2 years. The diagnosis of cancer seems to facilitate the early detection of dementia cases.
INTERNATIONAL PSYCHOGERIATRICS
(2023)
Article
Surgery
Jonathan Golledge, Ramesh Velu, Frank Quigley, Jason Jenkins, Tejas P. Singh
Summary: This study aimed to identify the biomarkers that can independently predict major adverse cardiovascular events (MACE) in patients with small abdominal aortic aneurysm (AAA), and found that C-reactive protein (CRP) can assist in classifying the risk of MACE.
JOURNAL OF VASCULAR SURGERY
(2023)
Letter
Surgery
Shivshankar Thanigaimani, Jonathan Golledge
JOURNAL OF VASCULAR SURGERY
(2023)
Editorial Material
Hematology
Costanza Emanueli, Ann Marie Schmidt, Jonathan Golledge
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Aaron Drovandi, Benjamin Crowley, Chanika Alahakoon, Leonard Seng, Malindu E. Fernando, Diane Ross, Rebecca Evans, Jonathan Golledge
Summary: In a study conducted in Queensland and Victoria, Australia, 16 individuals with a history of diabetes-related foot disease (DFD) were interviewed to explore their perceptions and experiences related to DFD management. The study found that improved access to offloading footwear and education about secondary prevention, provided through telehealth with support, is necessary for DFD patients.
AUSTRALIAN JOURNAL OF RURAL HEALTH
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Alessandra Granata, Eric L. Harshfield, Joseph Moxon
Summary: Cerebrovascular disorders are a global health concern, and advances in research have improved our understanding and management of these disorders. However, there are still gaps in our knowledge. BMC Cardiovascular Disorders invites authors to submit articles investigating the drivers and effects of cerebrovascular disorders to enhance patient care.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Endocrinology & Metabolism
Xiaoying Liu, Kaye E. Brock, Tara C. Brennan-Speranza, Leon Flicker, Jonathan Golledge, Graeme J. Hankey, Christian M. Girgis, Bu B. Yeap
Summary: Older people are more prone to vitamin D deficiency, and individual lifestyle factors have an impact on vitamin D levels. This study focused on older men and found that engaging in multiple healthy lifestyle behaviors, including physical activity, was associated with better vitamin D status. Further research is needed to determine the effects of promoting healthy lifestyle behaviors on vitamin D sufficiency.
CLINICAL ENDOCRINOLOGY
(2023)
Article
Surgery
Chanika Alahakoon, Tejas P. Singh, Dylan Morris, James Charles, Malindu Fernando, Peter Lazzarini, Joseph Moxon, Jonathan Golledge
Summary: This study investigated the distribution, severity, and outcome of peripheral artery disease (PAD) in Aboriginal and Torres Strait Islanders compared with non-indigenous Australians. The results showed that Aboriginal and Torres Strait Islander patients had a higher likelihood of presenting with chronic limb threatening ischaemia symptoms, more severe angiographic scores, particularly in the tibial arteries, and a higher risk of major amputation and major adverse cardiovascular events compared with non-indigenous Australians.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Article
Surgery
Chanika Alahakoon, Tejas P. Singh, Charith Galappaththy, James Charles, Malindu Fernando, Peter Lazzarini, Joseph Moxon, Jonathan Golledge
Summary: This study aimed to identify the rates and predictive factors for hospital re-admission among patients with diabetes related foot disease (DFD). The results showed that over 50% of patients were re-admitted within one year, and patients with absent pedal pulses and loss of protective sensation (LOPS) were twice as likely to be re-admitted.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Review
Peripheral Vascular Disease
Endre Kolossvary, Katalin Farkas, Oguz Karahan, Jonathan Golledge, Gerit-Holger Schernthaner, Thomas Karplus, Jonathan James Bernardo, Sascha Marschang, Maria Teresa Abola, Monica Heinzmann, Michael Edmonds, Mariella Catalano
Summary: Socio-economic determinants of health (SDoH) are nonmedical factors in the socio-economic sphere that significantly affect health outcomes, mediated by behavioral characteristics, physical environment, psychosocial circumstances, access to care, and biological factors. Research on the impact of SDoH on peripheral artery disease (PAD) occurrence and care is limited compared to cardiovascular diseases. This review explores the multifaceted nature of SDoH in PAD and their association with occurrence and care, while addressing methodological issues and the potential for interventions.
Review
Cardiac & Cardiovascular Systems
Jonathan Golledge, Shivshankar Thanigaimani, Janet T. Powell, Phil S. Tsao
Summary: Abdominal aortic aneurysm (AAA) causes a high number of deaths worldwide every year, but no drug therapy has been proven to effectively limit AAA growth in randomized controlled trials. Genome-wide association studies have identified potential drug targets, and treatments to reduce low-density lipoprotein cholesterol and smoking cessation are also being considered. However, previous placebo-controlled randomized trials have not shown convincing evidence of drug efficacy, mainly due to limitations such as small sample sizes and poor participant retention. Further large prospective studies on other targets are needed to address this issue.
EUROPEAN HEART JOURNAL
(2023)
Article
Oncology
Elizabeth H. Lim, Peter Franklin, Michelle L. Trevenen, Mark Nieuwenhuijsen, Bu B. Yeap, Osvaldo P. Almeida, Graeme J. Hankey, Jonathan Golledge, Christopher Etherton-Beer, Leon Flicker, Suzanne Robinson, Jane Heyworth
Summary: This study investigated the relationship between air pollution and lung cancer and bladder cancer in a low-pollution city. The results showed a weak positive association between ambient air pollution and squamous cell lung carcinoma, as well as a positive association with bladder cancer, although not statistically significant. The findings suggest that even low-level air pollution is associated with these cancers.
BRITISH JOURNAL OF CANCER
(2023)
Meeting Abstract
Surgery
G. A. Antoniou, N. Kontopodis, S. K. Rogers, J. Golledge, T. L. Forbes, F. Torella, H. J. M. Verhagen, M. L. Schermerhorn
JOURNAL OF VASCULAR SURGERY
(2023)
Review
Surgery
George A. Antoniou, Nikolaos Kontopodis, Steven K. Rogers, Jonathan Golledge, Thomas L. Forbes, Francesco Torella, Hence J. M. Verhagen, Marc L. Schermerhorn
Summary: The objective of this study is to compare the survival of patients who attended surveillance after endovascular aneurysm repair (EVAR) with those who were non-compliant. Thirteen cohort studies with a total of 22,762 patients were included. The results showed no statistically significant difference in the hazard of all cause mortality, aneurysm related mortality, or secondary intervention between patients who had incomplete and complete follow up after EVAR. The certainty of evidence was very low for all outcomes. The conclusion is that patients who were non-compliant with EVAR surveillance had similar survival to those who were compliant, questioning the value of intense surveillance in all patients post-EVAR and highlighting the need for further research on individualized or risk adjusted surveillance.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tejas P. P. Singh, Joseph V. V. Moxon, T. Christian Gasser, Jason Jenkins, Michael Bourke, Benard Bourke, Jonathan Golledge
Summary: The aim of this study was to assess the association between aortic peak wall stress (PWS) and peak wall rupture index (PWRI) and the risk of abdominal aortic aneurysm (AAA) rupture or repair (AAA events). PWS and PWRI were estimated from computed tomography angiography (CTA) scans of 210 participants with small AAAs. After a median follow-up of 2.0 years, it was found that both PWS and PWRI were significantly associated with a higher risk of AAA events. Furthermore, PWRI significantly improved the risk stratification compared to aortic diameter alone.
EUROPEAN RADIOLOGY
(2023)
