Article
Immunology
Janet D. Wilson, Harriet E. Wallace, Michelle Loftus-Keeling, Helen Ward, Bethan Davies, Armando Vargas-Palacios, Claire Hulme, Mark H. Wilcox
Summary: Through comparing clinician triple samples and self-taken pooled samples, it was found that self-taken pooled samples have similar sensitivity to clinician triple samples in identifying Neisseria gonorrhoeae in men who have sex with men and females, but have a slight difference in identifying Chlamydia trachomatis infections. Extragenital sampling can be achieved at no additional diagnostic cost to first-catch urine and vulvovaginal swabs.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Immunology
Olivia M. Man, Wilson E. Ramos, Gabriella Vavala, Cameron Goldbeck, Manuel A. Ocasio, Jasmine Fournier, Adriana Romero-Espinoza, M. Isabel Fernandez, Dallas Swendeman, Sung-Jae Lee, Scott Comulada, Mary Jane Rotheram-Borus, Jeffrey D. Klausner
Summary: Sexual behavior and gender identity can impact the detection of Chlamydia trachomatis and Neisseria gonorrhoeae infections at specific anatomic testing sites. Guidelines for testing should take into account sexual behavior and gender identity.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Dermatology
Ingibjorg Hilmarsdottir, Eva Mjoll Arnardottir, Elisabet Reykdal Johannesdottir, Daniel Golparian, Magnus Unemo
Summary: This study examined the prevalence and risk factors of Chlamydia trachomatis among attendees at a sexually transmitted infections clinic in Iceland. The findings revealed a high prevalence of C. trachomatis, with factors such as contact tracing, age, and number of sexual partners being associated with infection.
ACTA DERMATO-VENEREOLOGICA
(2021)
Review
Microbiology
Paul C. Adamson, Jeffrey D. Klausner
Summary: Chlamydia trachomatis and Neisseria gonorrhoeae are two commonly reported bacterial infections in the United States, with the rectum and oropharynx being important sites of infection. Nucleic acid amplification tests are widely used for detection of these infections. However, routine screening for pharyngeal specimens is not recommended.
JOURNAL OF CLINICAL MICROBIOLOGY
(2022)
Article
Immunology
Xiaohong Su, Wenjing Le, Xiaofeng Zhu, Sai Li, Baoxi Wang, Guillermo Madico, Zhaoyan Yang, Christine E. Chaisson, Robert E. McLaughlin, Sumanth Gandra, Jungwon Yoon, Bo Zheng, Lisa A. Lewis, Sunita Gulati, George W. Reed, Sanjay Ram, Peter A. Rice
Summary: This study compared the exposure of female partners to male gonococcal burdens in infected versus uninfected partners. The findings showed that gonococcal infections in women were more frequent when their partners had higher burdens of infection. Additionally, co-infection with Chlamydia was also associated with increased gonococcal burdens in women.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Microbiology
David C. Alexander, Robert M. Taylor, Irene Martin, Heather Adam, Philippe Lagace-Wiens, Peter Pieroni, James A. Karlowsky, Paul Van Caeseele
Summary: This study compared the performance of microscopy, culture, and the Hologic Aptima Combo 2 (AC2) assay for detecting Neisseria gonorrhoeae in joint fluid specimens. The results showed that AC2 was more sensitive than culture for diagnosing gonococcal arthritis.
JOURNAL OF CLINICAL MICROBIOLOGY
(2022)
Article
Immunology
Janet D. Wilson, Harriet E. Wallace, Michelle Loftus-Keeling, Helen Ward, Bethan Davies, Armando Vargas-Palacios, Claire Hulme, Mark H. Wilcox
Summary: The study found no difference in diagnostic accuracy between clinician-taken and self-taken extragenital samples from men who have sex with men and females. Sexual history was not able to identify those with rectal infections.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Brandie DePaoli Taylor, Ashley Hill, Maria J. Perez-Patron, Catherine L. Haggerty, Enrique F. Schisterman, Ashley Naimi, Akaninyene Noah, Camillia R. Comeaux
Summary: Hypertensive disorders of pregnancy (HDP) are associated with sexually transmitted infections, particularly Chlamydia and gonorrhea, which may increase the risk of severe preeclampsia.
SCIENTIFIC REPORTS
(2022)
Article
Andrology
Yumi Seo, Kyung-Hwa Choi, Gilho Lee
Summary: Co-infection with NG and CT may lead to gender-specific differences in clinical characteristics, and the co-infected population is increasing year by year, with young individuals having a bidirectional increase in the risk of co-infection.
WORLD JOURNAL OF MENS HEALTH
(2021)
Article
Infectious Diseases
Michelle Jayne Cole, Grahame S. Davis, Helen Fifer, John Michael Saunders, Magnus Unemo, Ronza Hadad, David J. Roberts, Mohammed Fazal, Michaela Joanne Day, Jack Minshull, Peter Muir, Paddy J. Horner, Noel O. Gill, Kate Folkard
Summary: A new variant of Chlamydia trachomatis (CT) was detected in Finland in 2019, which could escape detection in routine tests. Out of 317 discordant specimens collected from 315 patients, 46.7% tested positive for detectable CT DNA, but sequencing was successful for only 36 specimens.
SEXUALLY TRANSMITTED INFECTIONS
(2022)
Article
Infectious Diseases
Kristin M. Wall, Julien Nyombayire, Rachel Parker, Rosine Ingabire, Jean Bizimana, Jeannine Mukamuyango, Amelia Mazzei, Matt A. Price, Marie Aimee Unyuzimana, Amanda Tichacek, Susan Allen, Etienne Karita
Summary: An algorithm that bridges the gap between syndromic STI management and treatment based on realistic diagnostic options and local epidemiology is urgently needed in Africa. The study developed and validated a risk algorithm for NG and CT diagnosis among symptomatic Rwandan women, showing that the algorithm outperformed the current Rwandan National Criteria for NG/CT diagnosis.
BMC INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Rubee Dev, Shambhu P. Adhikari, Anjana Dongol, Surendra K. Madhup, Pooja Pradhan, Sunila Shakya, Shrinkhala Shrestha, Sneha Maskey, Melanie M. Taylor
Summary: This study aimed to estimate the prevalence of sexually transmitted infections (STIs) among pregnant women visiting an antenatal care center in Nepal, with a higher prevalence of trichomoniasis observed compared to other STIs such as Chlamydia and Gonorrhea.
Article
Infectious Diseases
A. Calas, N. Zemali, G. Camuset, J. Jaubert, R. Manaquin, C. Saint-Pastou, Y. Koumar, P. Poubeau, P. Gerardin, A. Bertolotti
Summary: This study evaluated the prevalence of CT, NG, and MG infections in patients visiting a French STI clinic in the Indian Ocean region, finding that routine multisite screening should be performed to reduce STI transmission in high-risk sexually active populations.
BMC INFECTIOUS DISEASES
(2021)
Article
Pediatrics
Vito Mondi, Chryssoula Tzialla, Salvatore Aversa, Daniele Merazzi, Stefano Martinelli, Gabriella Araimo, Luca Massenzi, Giacomo Cavallaro, Luigi Gagliardi, Fiammetta Piersigilli, Mario Giuffre, Simona Lozzi, Paolo Manzoni, Fabio Mosca, Irene Cetin, Vito Trojano, Herbert Valensise, Nicola Colacurci, Luigi Orfeo, Cinzia Auriti
Summary: Italy lacks clear legislation on prophylaxis for ophthalmia neonatorum, leading to variations in the use of prophylactic measures. A retrospective survey of birth centers in Italy shows that a majority of neonates received ophthalmic prophylaxis, but only a small percentage received the drugs recommended by the WHO. Incidence of neonatal conjunctivitis due to Chlamydia trachomatis and Neisseria gonorrhoeae was found to be low in Italy.
ITALIAN JOURNAL OF PEDIATRICS
(2023)
Article
Infectious Diseases
Nazir Ahmed Ismail, Shaheed Vally Omar, Harry Moultrie, Zaheda Bhyat, Francesca Conradie, M. Enwerem, Hannetjie Ferreira, Jennifer Hughes, Lavania Joseph, Yulene Kock, Vancy Letsaolo, Gary Maartens, Graeme Meintjes, Dumisani Ngcamu, Nana Okozi, Xavier Padanilam, Anja Reuter, Rodolf Romero, Simon Schaaf, Julian te Riele, Ebrahim Variava, Minty Van der Meulen, Farzana Ismail, Norbert Ndjeka
Summary: Analysis of data from South Africa showed a high prevalence of bedaquiline resistance, mainly associated with previous exposure to bedaquiline or clofazimine, rifampicin-resistant or MDR tuberculosis. Development of resistance led to poorer treatment outcomes.
LANCET INFECTIOUS DISEASES
(2022)