In situ imaging and proteome profiling indicate andrographolide is a highly promiscuous compound
出版年份 2015 全文链接
标题
In situ imaging and proteome profiling indicate andrographolide is a highly promiscuous compound
作者
关键词
-
出版物
Scientific Reports
Volume 5, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-06-24
DOI
10.1038/srep11522
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Development of a Natural-Product-Derived Chemical Toolbox for Modulation of Protein Function
- (2014) Stefano Rizzo et al. CHEMICAL REVIEWS
- Andrographolide: progression in its modifications and applications – a patent review (2012 – 2014)
- (2014) Chantana Aromdee EXPERT OPINION ON THERAPEUTIC PATENTS
- “Minimalist” Cyclopropene-Containing Photo-Cross-Linkers Suitable for Live-Cell Imaging and Affinity-Based Protein Labeling
- (2014) Zhengqiu Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cyanine-Based Fluorescent Probe for Highly Selective Detection of Glutathione in Cell Cultures and Live Mouse Tissues
- (2014) Jun Yin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Quantitative Chemical Proteomics Approach to Profile the Specific Cellular Targets of Andrographolide, a Promising Anticancer Agent That Suppresses Tumor Metastasis
- (2014) Jigang Wang et al. MOLECULAR & CELLULAR PROTEOMICS
- Natural product and natural product derived drugs in clinical trials
- (2014) Mark S. Butler et al. NATURAL PRODUCT REPORTS
- Chemistry: Chemical con artists foil drug discovery
- (2014) Jonathan Baell et al. NATURE
- A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors
- (2014) Bryan R Lanning et al. Nature Chemical Biology
- Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling
- (2013) Zhengqiu Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack
- (2013) Slava Ziegler et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Target identification of biologically active small molecules via in situ methods
- (2013) Ying Su et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Natural products as lead structures: chemical transformations to create lead-like libraries
- (2013) Mauro Pascolutti et al. DRUG DISCOVERY TODAY
- Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
- (2013) D. M. Molina et al. SCIENCE
- Target validation using in-cell small molecule clickable imaging probes
- (2013) Brahma Ghosh et al. MedChemComm
- A Switchable Two-Photon Membrane Tracer Capable of Imaging Membrane-Associated Protein Tyrosine Phosphatase Activities
- (2012) Lin Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes
- (2012) Marcel Deponte BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Nampt/Visfatin/PBEF: A Functionally Multi-faceted Protein with a Pivotal Role in Malignant Tumors
- (2012) He Jieyu et al. CURRENT PHARMACEUTICAL DESIGN
- Organelle-Specific Detection of Phosphatase Activities with Two-Photon Fluorogenic Probes in Cells and Tissues
- (2012) Lin Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cell-Based Proteome Profiling of Potential Dasatinib Targets by Use of Affinity-Based Probes
- (2012) Haibin Shi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- From noncovalent to covalent bonds: a paradigm shift in target protein identification
- (2012) Jongmin Park et al. Molecular BioSystems
- Electrophilic natural products and their biological targets
- (2012) Malte Gersch et al. NATURAL PRODUCT REPORTS
- Active site profiling reveals coupling between domains in SRC-family kinases
- (2012) Ratika Krishnamurty et al. Nature Chemical Biology
- Reaction-based small-molecule fluorescent probes for chemoselective bioimaging
- (2012) Jefferson Chan et al. Nature Chemistry
- Inhibition of TNF-α-Induced Inflammation by Andrographolide via Down-Regulation of the PI3K/Akt Signaling Pathway
- (2011) Haw-Wen Chen et al. JOURNAL OF NATURAL PRODUCTS
- Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)
- (2011) Mingyu Hu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma
- (2011) Ellen J. Gunn et al. LEUKEMIA & LYMPHOMA
- Synthesis, cytotoxicity, and structure–activity relationship (SAR) studies of andrographolide analogues as anti-cancer agent
- (2010) Bimolendu Das et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin
- (2009) Jing Zhou et al. BIOCHEMICAL PHARMACOLOGY
- Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat − An FDA-Approved Drug with Anti-Tumor Activities
- (2009) Peng-Yu Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry
- (2008) Benjamin F. Cravatt et al. Annual Review of Biochemistry
- Molecular Interaction between Andrographolide and Glutathione Follows Second Order Kinetics
- (2008) Zhiqiang Zhang et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- Identification of the cellular targets of bioactive small organic molecules using affinity reagents
- (2008) Benjamin J. Leslie et al. CHEMICAL SOCIETY REVIEWS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation