Article
Chemistry, Analytical
Shi-Hua Chen, Zong-Yin Song, Xiang-Yu Xiao, Hong-Qi Huang, Yuan-Fan Yang, Pei-Hua Li, Meng Yang, Xing-Jiu Huang
Summary: Vacancy and doping engineering were used to improve the electrocatalytic ability of nanomaterials for detecting heavy metal ions. The P-doped material showed enhanced sensitivity and selectivity towards As(III), and the vacancies provided abundant electrons to form active centers.
ANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Balla Fall, Abdou K. D. Diaw, Modou Fall, Mohamed L. Sall, Momath Lo, Diariatou Gningue-Sall, Musthafa Ottakam Thotiyl, Hanna J. Maria, Nandakumar Kalarikkal, Sabu Thomas
Summary: In this study, a highly sensitive nanocomposite material for the recognition of lead ions in aqueous medium was developed by combining rGO, CNT, and Fe2O3 on a GCE. The modified electrode exhibited excellent stability and conductivity, with a sensitivity of 162.8 mu A circle mu M (1) and a detection limit of 0.1 nM for Pb2+. The nanocomposite showed low metallic interference and good reproducibility for Pb2+ detection, demonstrating practical utility in tap water analysis.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Engineering, Environmental
Ruihua Huang, Jiapei Lv, Jianbing Chen, Yeling Zhu, Jian Zhu, Thomas Wagberg, Guangzhi Hu
Summary: This study proposes a boron and nitrogen co-doped carbon material derived from a metal-organic framework material for the detection of heavy metal ions in food. The sensor shows good sensitivity and selectivity for Cd(II) and Pb(II), and has potential applications in complex samples.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Inorganic & Nuclear
Tayyaba Kokab, Aalia Manzoor, Saima Aftab, Faiza Aslam, Faiza Jan Iftikhar, Humaira Masood Siddiqi, Afzal Shah
Summary: In this study, a sensitive and selective sensor based on BOC6-modified GCE was developed for the detection of Pb(II) ions. The electrochemical platform showed improved sensing performance compared to bare GCE. Under optimized conditions, the sensor exhibited a linear concentration range and a low detection limit for lead ions. It demonstrated qualities of sensitivity, selectivity, stability, reproducibility, and practical applicability.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
Ning Liu, Guo Zhao, Gang Liu
Summary: This study introduces a new method to detect Cd(II) and Pb(II) using feature stripping currents, which shows better anti-interference capability and detection accuracy. Models established using SVR and the partial least square algorithms demonstrate superior detection performance.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Ruihua Huang, Ke Zhang, Haowei Sun, Dafeng Zhang, Jian Zhu, Shuxing Zhou, Wenyan Li, Yongtao Li, Chunqiong Wang, Xiuxiu Jia, Thomas Wagberg, Guangzhi Hu
Summary: In this study, cetyltrimethylammonium bromide and zeolitic imidazolate framework-8 (ZIF-8) were assembled via chemical co-precipitation, and high-quality carbon-based metal-free nanomaterials were synthesized using heat treatment. The internal and morphological characteristics of hexagonal Star ZIF-8 were investigated. An electrochemical sensor with a good response to Cd(II) was prepared using Star ZIF-8 nanomaterial-modified electrodes. The sensitivity of the sensor was increased by five orders of magnitude.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Silvina Kergaravat, Natali Romero, Luciana Regaldo, Guillermo R. Castro, Silvia R. Hernandez, Ana Maria Gagneten
Summary: This research aimed to develop an electrochemical method for detecting CIP, AgNPs, and their mixtures and correlating them with ecotoxicological effects in aquatic organisms. The study found that AgNPs had the highest toxicity on C. dubia, followed by the CIP-AgNP mixture and then CIP alone. The stability of CIP and Ag(I) from AgNPs was evaluated, showing potential applications for environmental monitoring and highlighting the importance of electrochemical and ecotoxicology approaches in preserving environmental health.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Jing Ru, Xuemei Wang, Jiali Zhao, Jing Yang, Zheng Zhou, Xinzhen Du, Xiaoquan Lu
Summary: A novel platform based on UiO-67 MOF and PtNPs was developed for the detection of arsenic in wastewater. The platform exhibited high sensitivity, selectivity, and reliability, and could accurately monitor and measure arsenic in different environmental samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Gerardo Salinas, Bernardo A. A. Frontana-Uribe
Summary: In this study, we provide evidence of the interaction between conducting polymer and heavy metal ions through electrochemical and spectroscopic analysis. By comparing the behavior of two different conducting polymer-modified electrodes (PEDOT and PXDOT) during the potentiodynamic stripping of copper, we propose two different copper dissolution processes depending on the conducting polymer used. With PEDOT, stripping occurs in a two-step pathway involving the formation of Cu+-PEDOT complex and subsequent oxidation of the complex to release Cu2+ ions. On the other hand, the experiments suggest a poorly stable Cu2+-PXDOT complex or a superficial mechanism for Cu2+ release in the PXDOT system.
Article
Chemistry, Analytical
Gul Sirin Ustabasi, Ismail Yilmaz, Mustafa Ozcan, Ebru Cetinkaya
Summary: Pencil graphite electrode modified with MWCNT and Bi3+ showed improved sensitivity and reduced charge transfer resistance in the simultaneous analysis of Pb2+, Cd2+, and Zn2+. This modification method offers effective electroanalytical performance with low time consumption and cost.
Article
Chemistry, Applied
Fabiana Liendo, Amaya Paz de la Vega, Maria Jesus Aguirre, Fernando Godoy, Angel A. Marti, Erick Flores, Jaime Pizarro, Rodrigo Segura
Summary: A glassy carbon modified electrode with electroreduced graphene oxide was developed for the determination of Antimony (III) in commercial lettuce, celery, and beverages. The electrode surface was heterogeneous and rough, with a real area larger than a regular glassy carbon electrode. By using optimal chemical and electrochemical parameters, satisfactory results in terms of accuracy and reproducibility were obtained.
Article
Chemistry, Analytical
Manjunatha K. S. Kumara, D. H. Nagaraju, Zhoveta Yhobu, Nayan H. N. Kumar, Srinivasa Budagumpi, Shubhankar Kumar Bose, P. Shivakumar, Venkata Narayana Palakollu
Summary: In this study, researchers functionalized inexpensive and environmentally friendly Fe3O4 nanoparticles with D-valine using a co-precipitation synthetic approach. The resulting Fe3O4-D-Val sensor exhibited ultra-sensitive detection of Cd+2, Pb+2, and Cu+2 in water samples, with detection limits much lower than those suggested by the World Health Organization.
Article
Chemistry, Analytical
Aymara da Silva Santos, Carolina Zeni Pires Mecca, Tiago Luiz Ferreira, Fabio Ruiz Simoes, Lucia Codognoto, Eliana Maira Agostini Valle
Summary: The interaction between the pesticide carbendazim and the metal ion Pb2+ was studied using electrochemical techniques. The presence of Pb2+ affected the electrochemical signal of carbendazim, indicating complex formation. The electroanalytical method was found to be feasible for the analysis of carbendazim in the presence of Pb2+.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Mohammad Reza Jalali Sarvestani, Tayyebeh Madrakian, Abbas Afkhami
Summary: In this study, a highly sensitive electrochemical sensor was developed for the detection of ultra-trace levels of Pb2+. The sensor was modified with an in-situ electroplated bismuth film and a nanocomposite of a recently synthesized melamine based covalent organic framework and Fe3O4 nanoparticles. The combination of Fe3O4@SNW1 and the bismuth film significantly enhanced the sensitivity of the sensor towards Pb2+. The optimized sensor showed a linear response in the concentration range of 0.003-0.3 μmol L-1 with a detection limit of 0.95 nmol L-1. The sensor demonstrated good selectivity towards Pb2+ and was successfully applied for the determination of Pb2+ in different edible specimens.
Article
Chemistry, Analytical
Artur Huseinov, Abdul Hoque, Kyle A. Ruble, Brandon J. Dee, Noe T. Alvarez
Summary: This study presents a reagentless sample preparation method for the detection of particulate Pb contaminants in tap water using membrane electrolysis. The membrane electrolysis allows for the in-situ generation of nitric acid, which, when combined with anodic stripping voltammetry, provides a powerful and reagent-free detection of Pb2+. The setup configuration enables semi-autonomous operation and requires minimal attention, making it more suitable for continuous measurements of particulate contaminants in tap water.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Wenna Li, Kan Kan, Lang He, Laifeng Ma, Xueyi Zhang, Jiaqi Si, Muhammad Ikram, Mohib Ullah, Mawaz Khan, Keying Shi
APPLIED SURFACE SCIENCE
(2020)
Article
Engineering, Electrical & Electronic
Yang Wang, Jialing Xue, Xueyi Zhang, Jiaqi Si, Yang Liu, Laifeng Ma, Mohib Ullah, Muhammad Ikram, Li Li, Keying Shi
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
(2020)
Article
Chemistry, Physical
Muhammad Ikram, He Lv, Zhuo Liu, Mawaz Khan, Lujia Liu, Fazal Raziq, Xue Bai, Mohib Ullah, Yang Zhang, Keying Shi
CHEMISTRY OF MATERIALS
(2020)
Article
Chemistry, Physical
Jialing Xue, Xueyi Zhang, Mohib Ullah, Lang He, Muhammad Ikram, Mawaz Khan, Laifeng Ma, Li Li, Guo Zhang, Keying Shi
JOURNAL OF ALLOYS AND COMPOUNDS
(2020)
Article
Engineering, Environmental
Lujia Liu, Muhammad Ikram, Laifeng Ma, Xueyi Zhang, He Lv, Mohib Ullah, Mawaz Khan, Haitao Yu, Keying Shi
JOURNAL OF HAZARDOUS MATERIALS
(2020)
Article
Engineering, Environmental
Lang He, Hongyuan Wu, Wenyuan Zhang, Xue Bai, Junkun Chen, Muhammad Ikram, Ruihong Wang, Keying Shi
Summary: This work demonstrates a simple polymer thermal treatment strategy to develop high-dispersed Fe2O3/Fe@N-GC composites with a honeycomb-like N-doped graphitic carbon structure, which shows impressive sensitivity and selectivity for NO2 gas detection at room temperature. The optimal Fe2O3/Fe@N-GC composite exhibits a response of 25.48-100 ppm, response time of 2.13 s, recovery time of 11.73 s, detection limit of 10 ppb, and as long as 60 days of stability, making it a promising material for gas sensor applications.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Muhammad Ikram, Feifan Hu, Guogan Peng, Majid Basharat, Nawishta Jabeen, Ke Pan, Yongxiang Gao
Summary: Light-powered fuel-free colloidal motors have great potential for practical applications, but current colloidal motors often require expensive metals or toxic fuels. Integrating efficient materials into colloidal motors can improve their performance and benefit many applications.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Majid Basharat, Zameer Hussain Shah, Muhammad Ikram, Salah Eddine Ghellab, Qadeer-Ul Hassan, Tayiba Ilyas, Lijie Lei, Guanhua Lin, Yongxiang Gao
Summary: This study presents an inorganic-organic hybrid copolymeric poly(cyclotriphosphazene-co-barbituric acid)colloid with multiwavelength excited emission and catalytic activities. It demonstrates particle-resolved unusual multicolor emission under different wavelengths of light and rationalizes the results through density functional theory studies. The study also shows the use of these colloids as micropumps activated by light and explains the behavior as ionic diffusiophoresis arising from light-triggered generation of charged species. This work opens new opportunities in designing fuel-free, photo-actuated micromachines and active systems.
Article
Nanoscience & Nanotechnology
Shah Zeb, Yu Cui, Heng Zhao, Ying Sui, Zhen Yang, Zia Ullah Khan, Shah Masood Ahmad, Muhammad Ikram, Yongxiang Gao, Xuchuan Jiang
Summary: In this study, a gas sensor based on AuPdO modified Cu-doped K2W4O13 nanowires was developed to selectively detect 3-hydroxy-2-butanone and triethylamine. The sensor exhibited excellent sensing performance at reduced operating temperature, high selectivity, fast response/recovery, and stability. The gas sensor materials have potential applications in detecting toxic biomarkers and ensuring food and environmental safety.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Muhammad Ikram, Guogan Peng, Qadeer Ul Hassan, Majid Basharat, Yurou Li, Shah Zeb, Yongxiang Gao
Summary: A spindle-like iron-based metal-organic framework (MOF) colloidal motor is reported, which self-propels in glucose and H2O2 triggered by UV light. The motor exhibits distinctive chasing-escaping or schooling behaviors, depending on the fuel used.
Article
Chemistry, Physical
Ahmed Uddin, Abdur Rauf, Haopeng Luo, Majid Basharat, Muhammad Ikram, Shah Zeb, Muhammad Imran, Qadeer Ul Hassan, Yongxiang Gao
Summary: 3D/2D cubic In2O3/Copper doped graphitic carbon nitride (Cu-CN) heterojunction photocatalysts were synthesized and their photocatalytic properties for bisphenol-A (BPA) degradation were studied. The composites of In2O3/Cu-CN showed the highest photocatalytic activity at a 15% In2O3/Cu ratio under visible-light irradiation. The optimized composites displayed a 5-7 fold improvement compared to pure Cu-CN and/or In2O3. The improved photocatalytic behavior was attributed to the regulated In2O3/Cu-CN and the efficient separation of photo-induced electrons, as well as the transformation of the heterojunction interface.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Physical
Jiahui Fan, Lin Jiang, He Lv, Fangjie Qin, Yihe Fan, Jue Wang, Muhammad Ikram, Keying Shi
Summary: In this study, a mechanical stirring method was used to combine 3D ZIF-67 with 2D thin helical BiOCl nanosheets to form ZIF-67/BiOCl (ZBO) gas sensors. The ZBO sensor exhibited excellent gas-sensing performance for nitrogen dioxide detection at room temperature, showing great potential for practical applications in gas sensing.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Engineering, Environmental
Muhammad Imran, Ashraful Islam, Fatima Ismail, Panyue Zhang, Majid Basharat, Muhammad Ikram, Ahmed Uddin, Shah Zeb, Qadeer-Ul Qadeer-Ul Hassan, Yongxiang Gao
Summary: Aerogel with ultra-lightweight, special wettability, and porous structure has the potential to separate oil layer/water mixture. In this research, cost-effective mesoporous three-dimensional (3D) aerogel was designed and fabricated through a simple and green hydrothermal, synthetic method as a sorbent for efficient treatment of emulsified oil. The prepared grapefruit peel aerogel exhibited mesoporous structures with excellent hydrophobicity and regeneration capability.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Physical
Jiahui Fan, Jun Gao, He Lv, Lin Jiang, Fangjie Qin, Yihe Fan, Baihe Sun, Jue Wang, Muhammad Ikram, Keying Shi
Summary: This study reports a method to decorate BiOCl nanosheets on the surface of ultra-thin MXene, creating a BiOCl/MXene binary heterostructure. The sensor exhibits high response and low detection limits under high humidity conditions, as well as high response and fast response time under dry conditions. It also demonstrates good long-term stability and selectivity towards NO2 gas.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Chemistry, Physical
Muhammad Ikram, He Lv, Zhuo Liu, Keying Shi, Yongxiang Gao
Summary: A hydrothermal method was developed to convert rhombic MoS2@ZIF-8 into rodlike MoS2@ZnO heterostructure, enabling reliable NO2 gas sensing at room temperature.
JOURNAL OF MATERIALS CHEMISTRY A
(2021)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
