Article
Multidisciplinary Sciences
Alicia Fresno-Hernandez, Manuel Marques
Summary: This paper investigates the connection between the resonant cumulative field enhancement of a chain of plasmonic nanoparticles in a light field and the orientation of the chain. Analytical and numerical calculations are used to determine the optical torque and equilibrium configuration, and it is found that stable orientations are triggered by the geometric resonance conditions.
SCIENTIFIC REPORTS
(2022)
Article
Optics
Zekun Liao, Xiaofeng Hu, Jiao Chu, Yu Wu, Te Ji, Huachun Zhu, Weiwei Peng, Jie Wang, Hongwei Zhao, Min Chen
Summary: This paper proposes a novel and effective SERS-active substrate based on large-scale 3D Si hierarchical nanoarrays and homogeneous Au nanoparticles. The umbrella-frame structure achieved excellent SERS performance with high sensitivity and spatial uniformity. The proposed substrate can be erased and reused multiple times by plasma cleaning and exhibits excellent recyclability and stability for robust SERS activity.
Article
Materials Science, Multidisciplinary
Joshua Piaskowski, Georg Haberfehlner, Theresa Bartschmid, Gerald Kothleitner, Martin Steinhart, Gilles R. Bourret
Summary: Bimetallic AuRh_Au nanorod dimers with a thin lossy Rh segment in the gap region were synthesized using OWL. The E-field enhancement at the Rh segment and the coupling between the Au NR antennas were investigated using EELS, electromagnetic simulations, and SERS. Simple design rules for maximizing the E-field at a given wavelength within and on the Rh were provided. These bimetallic NR dimers are versatile platforms for studying plasmonic coupling in heterostructures and have potential applications in plasmonic catalysis.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Chemistry, Physical
Yan Zhao, Liheng Zheng, Shiyi Han, Bo Xu, Zheyu Fang, Jin Zhang, Lianming Tong
Summary: This study reveals the abrupt enhancement of Raman scattered light at the edges of two-dimensional (2D) materials, which is closely related to the polarization of the incident light. The edge structure also modulates the polarization and selection rule of Raman scattered light.
Article
Chemistry, Multidisciplinary
Yueshun Zhao, Bo Yang, Qiong Wu, Yunpeng Zhou, Fei Guo, Shifeng Zhao
Summary: The study introduces a method to regulate the performance of dielectric films by interacting polyhedral dipoles and forming domain energy. Experimental results show that a decrease in domain energy leads to domain reconstruction into smaller domains, while dipole regulation of A-O* enhances polarization, ultimately improving energy storage performance.
Article
Multidisciplinary Sciences
Wen Chen, Philippe Roelli, Huatian Hu, Sachin Verlekar, Sakthi Priya Amirtharaj, Angela Barreda, Tobias J. Kippenberg, Miroslavna Kovylina, Ewold Verhagen, Alejandro Martinez, Christophe Galland
Summary: Coherent upconversion of terahertz and mid-infrared signals into visible light was achieved using a plasmonic nanocavity hosting a few hundred molecules, demonstrating significant enhancement in upconversion efficiency per molecule. The results showcase that molecular cavity optomechanics is a flexible paradigm for frequency conversion leveraging tailorable molecular and plasmonic properties.
Article
Multidisciplinary Sciences
Saqib Jamil, Waqas Farooq, Najeeb Ullah, Adnan Daud Khan, Usman Khan Khalil, Amir Mosavi
Summary: This paper theoretically demonstrates the use of a plasmonic coupled elliptical nanostructure to achieve a high-intensity spaser or nanolaser. By altering the geometry, the structure can support strong coupled resonance modes and amplify the localized surface plasmon resonance (LSPR) peaks and the local field intensity. The study has important implications for sensing applications and surface-enhanced Raman spectroscopy.
Article
Materials Science, Multidisciplinary
Sung-Hyun Kim, Ha Young Lee, Jae-Hoon Ryu, Jeong-Yeon Lee, Han-Sol Kim, Hyung Soo Ahn, Dong Han Ha, Sam Nyung Yi
Summary: This study aimed to enhance surface plasmon resonance by combining Ag nanoparticles and an asymmetric crater structure. The results showed that the Raman intensity inside the crater with Ag nanoparticles and nanowires was 22 times higher compared to a flat area without nanoparticles. However, an increase in the amount of nanowires led to a decrease in Raman intensity.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Xudong Cheng, Jing Jin, Mengting Shi, Minghui Ge, Jinqi Miao, Cheng Ci, Zhenyu Xue, Peimei Dong
Summary: A facile and green synthesis strategy was used to prepare a uniform three-dimensional (3D) nanostructure as surface-enhanced Raman scattering (SERS) sensors by decorating Ag nanoparticles (AgNPs) on TiO2 nanorod arrays. The AgNPs were distributed uniformly on the surface of TiO2 nanorods, as confirmed by XPS, SEM, and TEM analyses. The 3D hybrid substrate exhibited sensitive SERS signals and excellent spatial uniformity. The results also demonstrated the promising potential of the two-step synthesis strategy for preparing 3D hybrid nanostructure substrates for SERS.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Zhenyu Cai, Jun Shen, Maozhuang Zhang, Liang Cui, Wei Liu, Jingquan Liu
Summary: In this study, a unique nanocomposite of CuxO@CoNi-LDH with a hierarchical nanostructure was synthesized by a fast electrodeposition method. The resulting electrocatalyst showed high catalytic performance and long-term stability in the oxygen evolution reaction.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Physics, Multidisciplinary
Usman Khan Khalil, Waqas Farooq, Javed Iqbal, Syed Zain Ul Abideen Kazmi, Adnan Daud Khan, Anees Ur Rehman, Saba Ayub
Summary: This paper proposed three different configurations of bowtie nanoantennas, optimized the size parameters to achieve maximum near field enhancement, and found that the Triple Bowtie Structure (TBS) delivers the highest enhancement factor with a triple resonance peak. Moreover, the study showed that the enhancement decreases as the antenna size reduces.
EUROPEAN PHYSICAL JOURNAL PLUS
(2021)
Article
Nanoscience & Nanotechnology
Jianhua Zhang, Liujun Jin, Peiyang Gu, Lei Hu, Dongyun Chen, Jinghui He, Qingfeng Xu, Jianmei Lu
Summary: Urea oxidation as an alternative to oxygen evolution reactions has the potential to save energy and remove urea from polluted water. The electrocatalyst developed using FeCoNi-LDH nanorods shows superior catalytic activity in 1.0 M KOH solution. The introduction of sodium nitroprusside induces a large number of active sites and rapid charge transfer in the system.
ACS APPLIED NANO MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Sergio Kogikoski, Kosti Tapio, Robert Edler von Zander, Peter Saalfrank, Ilko Bald
Summary: Surface-enhanced Raman scattering is a powerful method to detect molecules at very low concentrations. In this study, gold nanoparticle dimers were self-assembled using DNA origami nanotriangles, with Cy5 and TAMRA as SERS probes. The results showed that the EFs for the dimeric assemblies follow a log-normal distribution and that plasmonic resonance is the main source of the observed signal.
Article
Chemistry, Inorganic & Nuclear
Meiling Hong, Lidong Dai, Haiying Hu, Xinyu Zhang, Chuang Li, Xiaolei Feng, Shidong Yu, Limin Zhang, Zhongying Mi, Sivakumar Aswathappa
Summary: In this study, the high-pressure structural and electronic transitions of SbI3 under different hydrostatic environments were investigated using synchrotron X-ray diffraction, Raman spectroscopy, electrical conductivity, and first-principles theoretical calculations. It was found that SbI3 exhibited an electronic transition from semiconductor to metal at 32.3 GPa under non-hydrostatic conditions. A pressure hysteresis of about 5.0 GPa was observed for the metallization of SbI3 under hydrostatic conditions, possibly due to the faint deviatoric stress. Moreover, the phase transition of SbI3 was found to be irreversible under different hydrostatic environments. This study provides insights into the correlations between crystalline and electronic structures and may facilitate the application of quasimolecular layered crystals in optoelectronic devices.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Optics
Tianan Yi, Wei Su, Qiang Yu, Hua Wu, Kun Guo, Haiqing Deng, Cheng Yin, Juntao Yan, Jian Wu, Bingyan Chen
Summary: This study presents a flexible SERS substrate with high sensitivity, low cost, simple processing, high yield, and good activity by modifying the flexible substrate using corona discharge technique. The modified substrate showed high sensitivity to Rhodamine 6G and exhibited a significant enhancement effect.
Article
Materials Science, Multidisciplinary
G. Marimuthu, Ba-Son Nguyen, Van-Toan Pham, Van-Huy Nguyen, Van-Man Tran, Kundan Sivashanmugan, T. Pazhanivel
Summary: The study introduced a simple and inexpensive hydrothermal method to prepare a NiCo2O4/MWCNTs sensor, which showed the highest capacitance at 10 kHz and exhibited excellent sensitivity for NH3 gas detection at room temperature.
Article
Biochemistry & Molecular Biology
Chao-Liang Wu, Chao-Wei Chuang, Hsin-Yen Cho, Tzu-Hsien Chuang, Sheng-Nan Wu
Summary: The research found that Mirogabalin can alleviate peripheral neuropathic pain and diabetic neuropathy by suppressing the peak and sustained components of the voltage-gated Na+ current. However, the specific mechanisms are still largely unknown.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Kuan-Ming Lai, Jou-Hsuan Wang, Shih-Chao Lin, Ya Wen, Chao-Liang Wu, Jui-Hsin Su, Chien-Chin Chen, Chi-Chien Lin
Summary: In this study, the anticancer effects of Crassolide, extracted from soft coral, on non-small-cell lung cancer cells were assessed. Crassolide was found to inhibit malignant behaviors of the cancer cells by inducing cell cycle arrest, apoptosis, and autophagy, activated through ROS accumulation and ER stress pathway.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Chao-Liang Wu, Poyuan Fu, Hsin-Yen Cho, Tzu-Hsien Chuang, Sheng-Nan Wu
Summary: QO-58 is considered to be an activator of K(V)7 channels with analgesic properties and has concentration-dependent effects on M-type K+ current and Ca2+-activated K+ current. Additionally, it increases the activity of BKCa channels while having a minor effect on the erg-mediated K+ current.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Sheng-Nan Wu, Chao-Liang Wu, Hsin-Yen Cho, Chi-Wu Chiang
Summary: This article investigates the influence of various small-molecule modulators on the Hys((V)) strength of different types of ionic currents elicited by a triangular V-ramp. The results suggest that these modulators can alter the Hys((V)) properties of the ionic currents and may impact the electrical behaviors of cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Shih-Yao Chen, Ting-Chien Tsai, Yuan-Tsung Li, Yun-Chiao Ding, Chung-Teng Wang, Jeng-Long Hsieh, Chao-Liang Wu, Po-Ting Wu, Ai-Li Shiau
Summary: This study demonstrates that IL-23 promotes osteoclastogenesis through transcriptional regulation of miR-223 in murine macrophages and mice with CIA. Furthermore, the study suggests that LSF, a selective inhibitor of STAT4, could be an ideal therapeutic agent for treating rheumatoid arthritis by reducing miR-223-mediated osteoclastogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Medicine, Research & Experimental
Shih-Yao Chen, I-Ming Jou, Po-Yen Ko, Kai-Lan Hsu, Wei-Ren Su, Li-Chieh Kuo, Pei-Yuan Lee, Chao-Liang Wu, Po-Ting Wu
Summary: CD44 protects tendinopathic tendons from senescence-associated secretory phenotypes through anti-inflammation and maintenance of extracellular matrix homeostasis.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT
(2022)
Article
Biochemistry & Molecular Biology
Mao-Hsun Lin, Jen-Feng Lin, Meng-Cheng Yu, Sheng-Nan Wu, Chao-Liang Wu, Hsin-Yen Cho
Summary: This study found that Deltamethrin (DLT) and related compounds can stimulate voltage-gated sodium current in pituitary tumor cells, potentially altering gating characteristics, frequency dependence, and voltage-dependent hysteresis behavior.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Respiratory System
Tang-Hsiu Huang, Sheng-Huan Wei, Li-Ting Huang, Hong-Ping Er, Yu-Ting Yu, Chung-Ta Lee, Yau-Lin Tseng, Chao-Liang Wu
Summary: This study investigated the impact of CT patterns and extent of OP on the diagnostic and therapeutic management of patients. It found that patients with multilobe involvement or mixed patterns were more likely to have secondary OP and receive immunosuppressants. These patients also had a higher risk of recurrence and severe disease, and decreased survival probabilities.
Article
Biochemistry & Molecular Biology
Shih-Yao Chen, Chung-Teng Wang, Ching-Yi Chen, Pin-Yu Kuo, Chrong-Reen Wang, Ai-Li Shiau, Cheng-Hsi Chang, Chao-Liang Wu
Summary: In this study, researchers found that the expression levels of galectin-3 were higher in the peripheral blood mononuclear cells of SLE patients compared with normal individuals and positively correlated with lupus nephritis and SLE disease activity index. They also observed NETosis in normal individuals, SLE patients, and galectin-3 knockout mice. Furthermore, galectin-3 was found to be associated with NETs and immune complex deposition in SLE patients. These findings provide clinical relevance of galectin-3 in SLE and offer insights into the underlying mechanisms of galectin-3-mediated NETosis for developing novel therapeutic strategies targeting galectin-3 for SLE.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Microbiology
Shih-Yao Chen, Chun-Ting Chu, Mei-Lin Yang, Jian-Da Lin, Chung-Teng Wang, Che-Hsin Lee, I-Chen Lin, Ai-Li Shiau, Pin Ling, Chao-Liang Wu
Summary: Imbalance of mucosal immunity in the lower gastrointestinal tract can lead to chronic inflammatory bowel diseases (IBDs). Previous studies have shown that IL-10 protein and genetically modified bacteria secreting IL-10 can ameliorate colitis in mice. This study investigated the potential of Salmonella choleraesuis carrying the murine IL-19 gene to treat IBD and found promising results in reducing mortality and clinical signs in mice with DSS-induced colitis.
Article
Biochemistry & Molecular Biology
Chih-Yu Ting, Chia-Lung Shih, Meng-Cheng Yu, Chao-Liang Wu, Sheng-Nan Wu
Summary: Omecamtiv mecarbil (OM, CK-1827452) is an activator of myosin and has been shown to be beneficial for the treatment of systolic heart failure. However, its effects on ionic currents in electrically excitable cells are not well understood. This study investigated the effects of OM on ionic currents in GH3 pituitary cells and Neuro-2a neuroblastoma cells.
Article
Virology
Ai-Li Shiau, Kuan-Hsien Lee, Hsin-Yen Cho, Tzu-Hsien Chuang, Meng-Cheng Yu, Chao-Liang Wu, Sheng-Nan Wu
Summary: Molnupiravir is an oral ribonucleoside prodrug used for the treatment of COVID-19. It can cause adverse effects such as headache, diarrhea, and nausea, possibly due to its impact on sodium channel function. In this study, the researchers investigated the effect of Molnupiravir on voltage-gated Na+ current in pituitary GH3 cells and found that it had specific effects on both transient and late Na+ currents, as well as altering the inactivation time constant of the slow component of Na+ current. The IC50 values for Molnupiravir in inhibiting transient and late Na+ currents were 26.1 and 6.3 μM, respectively. The study suggests that the alteration of Na+ currents by Molnupiravir may have important physiological implications and contribute to its pharmacological activity or adverse events.
Article
Biochemistry & Molecular Biology
Che-Yuan Hu, Chi-Feng Hung, Pi-Che Chen, Jia-Yu Hsu, Chung-Teng Wang, Ming-Derg Lai, Yuh-Shyan Tsai, Ai-Li Shiau, Gia-Shing Shieh, Chao-Liang Wu
Summary: DCIR, an immunoreceptor, plays a role in inhibiting antitumor activity. The study demonstrates that using an oncolytic adenovirus can decrease the expression of DCIR in mice, inhibiting tumor growth and inducing stronger immune responses.
Article
Biochemistry & Molecular Biology
Che-Yuan Hu, Hung-Tsung Wu, Yan-Shen Shan, Chung-Teng Wang, Gia-Shing Shieh, Chao-Liang Wu, Horng-Yih Ou
Summary: Evodiamine (EVO) inhibits cell proliferation and induces ferroptosis in bladder cancer cells, as shown by decreased lipid peroxide levels and GPX4 expression. EVO treatment also suppresses tumor growth and epithelial-mesenchymal transition (EMT) in a bladder tumor xenograft model. These findings suggest that EVO may be a potential therapeutic agent for bladder cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
