Article
Environmental Sciences
Qiao-Fen Pan, Hai-Feng Jiao, Hua Liu, Jin-Jie You, Ai-Li Sun, Ze-Ming Zhang, Xi-Zhi Shi
Summary: A novel MIECL sensor based on MIP-CsPbBr3 and Ru(bpy)32+ was developed for simazine detection. The sensor showed excellent selectivity, sensitivity, and reproducibility, and could accurately determine the concentration of simazine in actual aquatic samples.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Qiao-Fen Pan, Hai-Feng Jiao, Hua Liu, Jin-Jie You, Ai-Li Sun, Ze-Ming Zhang, Xi-Zhi Shi
Summary: A novel molecularly imprinted electrochemiluminescence sensor has been developed for simazine detection, showing high sensitivity and accuracy. Application in aquatic samples demonstrates excellent selectivity and reproducibility of the sensor.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Analytical
Ze Zhang, Hongwei Yu, Yingcong Zhang, Zhangmin Wang, Hongmin Gao, Shengzhong Rong, Lingqiang Meng, Jianmin Dai, Hongzhi Pan, Dong Chang
Summary: A sandwich-format electrochemiluminescence immunosensor was developed for alpha-fetoprotein detection, utilizing ordered mesoporous carbon-molybdenum disulfide as a sensor platform and cuprous oxide @ ordered mesoporous carbon-Ru composites as signal tags. Under optimal experimental conditions, the sensor demonstrated a wide linear range and a low detection limit.
Article
Chemistry, Analytical
Lu Zheng, Qingfu Guo, Chaonan Yang, Jingjing Wang, Xuejiao Xu, Guangming Nie
Summary: A novel dual-signal immunosensor based on Ru(bpy)32+/MOF (Ru-MOF) composite material is developed for the detection of prostate-specific antigen (PSA) through electrochemiluminescence (ECL) and photoelectrochemistry (PEC). The Ru-MOF film exhibits strong ECL signals coexisted with K2S2O8 and good PEC property under light. By introducing Cu2O-coated Pd shell-core-structured nanoparticles (Pd/Cu2O) as a quencher, the ECL and PEC intensity can be efficiently quenched, allowing successful construction of the dual-signal immune sensor for PSA detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Yingjie Zhao, Li Tian, Xin Zhang, Zhuo Sun, Xiangyu Shan, Qian Wu, Ruizhan Chen, Juan Lu
Summary: A specificity recognition molecularly imprinted electrochemiluminescence sensor (MIECLS) for determination of clenbuterol (CLB) was established, with a detection limit of 3.3 x 10(-10) mol L-1. The sensor utilized Fe2O3 as the carrier to fix Ru(bpy)(3)(2+), and introduced molecular imprinted membranes (MIPs) with CLB as template molecules to achieve specificity identification, showing great potential in pork and liver samples testing.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Applied
Xin Zhang, Li Tian, Zhuo Sun, Qian Wu, Xiangyu Shan, Yingjie Zhao, Ruizhan Chen, Juan Lu
Summary: A molecular-imprinted electrochemiluminescence sensor based on Ru(bpy)32+@ZIF-7 was developed for procymidone detection. The sensor exhibited high sensitivity, selectivity and stability, with a wide linear range and low detection limit.
Article
Chemistry, Analytical
Qiaoling Liu, Wenjia Bai, Zhihui Guo, Xingwang Zheng
Summary: A novel scheme was developed to enhance the chemical affinity and electric conductivity between Ru(bpy)(3)(2+)-doped silica nanoparticles and carbon nanotubes (CNT) by electrochemically depositing a nanoscale chitosan hydrogel layer on the CNT surface. This scheme improved the ECL effectivity of Ru(bpy)(3)(2+) inside silica nanoparticles, leading to the development of a highly sensitive ECL method for miRNA detection.
Article
Chemistry, Analytical
Chenhong Yu, Li Li, Yaping Ding, Huajie Liu, Hanyue Cui
Summary: This paper introduces a novel electrochemical aptasensor for trace analysis of cortisol, which integrates molecular imprinting techniques. The sensor, based on functionalized graphene and nitrogen-doped carbon quantum dots, exhibits linearity and a low detection limit. Moreover, it can determine cortisol in salivary samples with high recovery values.
Article
Chemistry, Analytical
Guanhui Zhao, Yu Du, Nuo Zhang, Yuan Li, Guozhen Bai, Hongmin Ma, Dan Wu, Wei Cao, Qin Wei
Summary: To ensure drinking water quality, the development of rapid and accurate analytical methods is essential. In this study, a highly sensitive electrochemiluminescence (ECL) aptasensor based on a signal on-off-on strategy was developed to detect the water pollutant microcystin-LR (MC-LR). The aptasensor exhibited outstanding sensitivity and stability in MC-LR detection, with a linear detection range of 0.0001-50 ng mL(-1). The study provides valuable directions for the application of alloy nanoparticles of noble metals and bimetallic MOFs in the field of ECL immunoassay.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Tesfaye Hailemariam Barkae, Shuai Quan, Zhiyong Dong, Kaixiang Ji, Altaf Hussain, Abdallah M. Zeid, Guobao Xu
Summary: This study explores the use of gramine as a coreactant in Ru(bpy)(3)(2+) electrochemiluminescence, enabling the detection of gramine in a wide linear range with a low limit of detection. The method was validated using beer samples, showing promising results.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Biomaterials
Shuang He, Qiaoling Liu, Yu Ji, Pei Zhang, Chusen Huang, Jing Sun, Yao Lu, Da-Peng Yang, Nengqin Jia
Summary: An electrochemiluminescent (ECL) sensor using Ru(bpy)(3)(2+) encapsulated by MIL-NH2-101(Al) nanocomposites has been developed for the sensitive detection of the thrombus marker thrombomodulin (TM), showing ideal stability, selectivity, and reproducibility.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Chemistry, Analytical
Anabel Laza, Ana Godoy, Sirley Pereira, Pedro R. Aranda, Carlos D. Garcia, Julio Raba, Franco A. Bertolino
Summary: A simple sensor for the determination of progesterone has been developed using a molecularly imprinted polymer. The sensor showed good linear response, selectivity, and stability, making it a promising alternative for analysis of progesterone.
MICROCHEMICAL JOURNAL
(2022)
Article
Multidisciplinary Sciences
Shijun Wang, Shu Zhu, Ziili Kang, Xiangxiu Wang, Zixin Deng, Kun Hu, Jianjun Hu, Xiancheng Liu, Guixue Wang, Guangchao Zang, Yuchan Zhang
Summary: In this study, gold nanoparticles/reduced graphene oxide (Au/rGO) composites were synthesized to promote and modulate the luminescence of tris(2,2 ' -bipyridine) ruthenium(II) (Ru(bpy)32+). The size of the gold nanoparticles affected the luminescence of Ru(bpy)32+. This method achieved a good linear range and a low limit of detection for detecting carcinoembryonic antigen.
Article
Chemistry, Analytical
Ziying Zhong, Yun Tang, Yanran Chen, Chunfang Wang, Faqiong Zhao, Baizhao Zeng
Summary: A simple and sensitive electrochemiluminescence (ECL) sensor was prepared for tetracycline detection. The sensor showed a wide linear range, high selectivity, low detection limit, and good stability, making it suitable for food and environmental sample analysis.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Tesfaye Hailemariam Barkae, Abdallah M. Zeid, Shuai Quan, Muhammad Rehan Hasan Shah Gilani, Baohua Lou, Guobao Xu
Summary: A new Ru(bpy)32+ electrochemiluminescence (ECL) system has been developed for sensitive, cost-effective, rapid, and specific detection of Hexamethylphosphoramide (HMPA), with high percentage recoveries in real samples of lake water and waste water. The system enables analysis of HMPA over a wide dynamic range with a low detection limit.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)