Novel determination of hydrogen peroxide by electrochemically reduced graphene oxide grafted with aminothiophenol-Pd nanoparticles

Graphene oxide (GO) has functionalized with aminothiophenol (ATP) and covalently bonded to the palladium (Pd) nanoparticles (NPs) via sulfur atom. The GO-ATP-Pd was electrochemically reduced to graphene oxide (ERGO) at a potential range of 0 to -1.5 V, and was used in electrochemical biosensing for hydrogen peroxide (H2O2). The ERGO-ATP-Pd-modified electrode showed the advantages of excellent electrocatalytic activity toward H2O2 in PBS solution. The ERGO-ATP-Pd was characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), energy dispersive X-ray spectroscopy (EDS) and electrochemical impedance spectroscopy (EIS). Cyclic voltammetry (CV) and chronoamperometry (CA) were used to characterize the performance of the biosensor. The proposed H2O2 biosensor exhibited a wide linear range from 0.1 mu M to 10 mM, and a low detection limit of 0.016 mu M (S/N = 3), with a fast response time of less than 10 s. The biosensor, therefore, demonstrated excellent capability for the analysis of H2O2. (c) 2013 Elsevier B.V. All rights reserved.