Article
Chemistry, Analytical
E. Spagnoli, S. Krik, B. Fabbri, M. Valt, M. Ardit, A. Gaiardo, L. Vanzetti, M. Della Ciana, V Cristino, G. Vola, S. Caramori, C. Malagu, V Guidi
Summary: Tungsten oxide nanoflake powders were synthesized using solvothermal technique for ethanol sensing, showing good response to ethanol compared to other alcohols due to an interplay between the catalytic properties of the sensing film and gas diffusivity in a porous medium.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Cristine Santos de Oliveira, Erico Teixeira Neto, Italo Odone Mazali
Summary: The development of CeO2-based nanomaterials for catalysis has significantly grown in the past decade, with applications such as the water-gas shift reaction (WGSR) showing higher catalytical activity when combined with noble metal nanoparticles. This study designed a material for the catalysis of the WGSR, optimizing Au nanoparticle size and maintenance during catalysis to prevent the formation of undesired side products, achieving stable catalytic activity even at higher temperatures.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Analytical
Aihua Yu, Zhou Li, Jianxin Yi
Summary: This study presents a strategy for synthesizing Pt-functionalized ZnO nanorod arrays for detecting ppb-level H2S gas, showing high sensitivity and selectivity. The enhanced sensing performance can be attributed to the catalytic and electronic promotion effects of Pt and the unique morphology of nanorods.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Gwang Su Kim, Yumin Park, Joonchul Shin, Young Geun Song, Chong-Yun Kang
Summary: Gas phase chemical analysis for breath gas monitoring has great potential. Array-type sensors with high sensitivity and selectivity for target gases, combined with micro-heater and ceramic chip, show excellent detection performance. Sensor array decorated with metal catalysts can detect biomarkers CH3COCH3, NO2, and H2S for real-time monitoring.
Article
Materials Science, Ceramics
Kyusung Kim, Pil Gyu Choi, Toshio Itoh, Yoshitake Masuda
Summary: By changing the supply rate of hydroxide ions, we can control the morphology of ZnO nanomaterial and improve the sensitivity of metal-oxide-semiconductor gas sensors.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2023)
Article
Chemistry, Analytical
Shichao Wang, Xiaohu Wang, Gaoqun Qiao, Xiaoyan Chen, Xinzhen Wang, Hongzhi Cui
Summary: Core-double shell-structured ZnO@In2O3@ZnO microspheres were successfully synthesized by decorating In2O3 and ZnO on the surface of ZnO hollow microspheres, exhibiting excellent gas sensing properties with high response to gases like ethanol, especially at low concentrations. This superior gas sensing performance was attributed to its high specific surface area, abundant surface defects, and radial electronic modulation mechanism.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Nanoscience & Nanotechnology
Mengli Lei, Meiqi Gao, Xuanyu Yang, Yidong Zou, Abdulaziz Alghamdi, Yuan Ren, Yonghui Deng
Summary: The mesoporous ZnO-Au composites prepared by photoreduction exhibit superior ethanol sensing performance, attributed to their excellent physical structure and interface effects. Compared to other noble metals, mesoporous ZnO-Au shows higher selectivity and sensitivity to ethanol.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Ceramics
Aditya Yadav, Anuj Sharma, Vishal Baloria, Preetam Singh, Govind Gupta
Summary: This study reports the growth of nanostructured tungsten oxide (WO3) thin film on SiO2 substrate under controlled oxidation conditions for NO sensing. The fabricated sensor demonstrates high selectivity, stability, and faster response/recovery time, with an ultra-high response for 1 ppm NO concentration at 250 degrees C. The ultra-high response is attributed to the high specific surface area and effective gas diffusion ability of the sensor.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Multidisciplinary
Fei Li, Qian Lv, Lun Gao, Xing Zhong, Jing Zhou, Xiaoxin Gao
Summary: Ag-LaFeO3, prepared by chemical reduction method, demonstrates excellent gas-sensing properties towards ethanol, with a higher gas response compared to LaFeO3 sensor, and short response and recovery times.
JOURNAL OF MATERIALS SCIENCE
(2021)
Article
Optics
Haitham T. Hussein, Muna H. Kareem, Adi M. Abdul Hussein
Summary: This study prepared a high-quality gas sensor by adding carbon nanotubes and zinc oxide nanoparticles doped with porous silicon layers. The CNTs-ZnO/PS sample showed the highest sensitivity to ethanol gas, reaching 2.004984 at a concentration of 500 ppm, demonstrating excellent sensing ability.
Article
Chemistry, Physical
Haili Huang, Zhentao Du, Hung-Chun Wu, Fengmei Gao, Lan Jiang, Huilin Hou, Shanliang Chen, Weijun Li, Feng Hu, Weiyou Yang, Dongdong Zhang, Lin Wang
Summary: In this study, a high-temperature resistant ethanol sensor based on rationally designed heterojunctions is constructed, exhibiting significantly improved performance in sensing ethanol at 465 degrees C. The sensor demonstrates high response, fast detection, and excellent selectivity, suggesting promising applications for stable sensors operating under harsh working conditions.
APPLIED SURFACE SCIENCE
(2024)
Article
Engineering, Electrical & Electronic
Ruichen Liu, Dongcheng Xie, George Adedokun, Feng Xue, Lei Xu, Feng Wu
Summary: This paper presents a ZnO-based gas sensor fabricated using MEMS process, featuring a narrow bridge-type micro-heater with ultra-low static power consumption. By depositing sensing materials on the heater using PVD sputtering, a sandwiched ZnO/Au/ZnO structure was formed to enhance sensitivity to ethanol. The sensor achieved a best sensitivity of 15 (R-air/R-gas) to 100 ppm ethanol while consuming a low power of 12.17 mW.
IEEE SENSORS JOURNAL
(2021)
Article
Chemistry, Analytical
Yoshitake Masuda
Summary: This review focuses on tin oxide nanomaterials, which are actively researched as semiconductor-type gas sensors. The development and applications of novel tin oxide nanomaterials in the past decade are discussed, with a focus on how dimensions and morphology affect sensing performance. The dendritic structure formed by 2D nanosheets connected by crystal growth points towards future sensor development, while the high gas adsorption performance and reactivity of metastable crystal planes provide guidance for future sensor development.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Jun Min Suh, Tae Hyung Lee, Kootak Hong, Young Geun Song, Sung Hwan Cho, Chong-Yun Kang, Young-Seok Shim, Donghwa Lee, Ki Chang Kwon, Ho Won Jang
Summary: The heterostructure between two-dimensional metal sulfides and metal oxides is an effective strategy to enhance the gas sensing performance. This study focuses on enhancing gas sensing response under highly humid conditions by using 2D tin sulfides-SnO2 heterostructures in the form of vertically aligned 1D nanostructures. The results show superior gas response and recovery to NO2 under high humidity, as well as diverse selectivity towards various gases using noble metal catalyst decoration.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Physical
Anees A. Ansari, Manawwer Alam, Md Azahar Ali
Summary: The study introduces an electrochemical sensor for the detection of 4-nitrophenol using CeO2:Ag nanoparticles without the need for enzymes. The CeO2:Ag NPs demonstrated enhanced electro-oxidation properties, leading to improved sensing efficacy for nitrophenol detection, and have potential applications for sensitive detection of other hazardous substances.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Pharmacology & Pharmacy
N. Ghanbari, Z. Salehi, A. A. Khodadadi, M. A. Shokrgozar, A. A. Saboury, F. Farzaneh
Summary: In this study, Tryptophan-conjugated graphene quantum dots (Trp-GQDs) loaded with Curcumin (Cur) as an anticancer agent were successfully fabricated and evaluated for their drug loading capacity, release kinetics, and cytotoxicity on human breast cancer cells. The nano-assemblies showed high drug loading capacity, pH-sensitive release, and non-toxicity on MCF-7 cells, indicating their potential as promising candidates for drug delivery applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Chemical
Zahra Farshidrokh, Mohammad Reza Khani, Abbasali Khodadadi, Mahtab Gharibi, Babak Shokri
Summary: The study investigated dry reforming of methane (DRM) over Ni/gamma-MgO catalysts in a coaxial dielectric barrier discharge (DBD) reactor and compared it with DRM without catalysts. The presence of catalysts in the plasma reactor increased the yield and selectivity of H-2 and CO. The reduced catalyst Ni/7%CeO2/MgO showed excellent CH4 conversion performance, providing a new approach to further improve the methane conversion rate.
CHEMICAL ENGINEERING & TECHNOLOGY
(2021)
Article
Materials Science, Biomaterials
Narges Ghanbari, Zeinab Salehi, Abbas Ali Khodadadi, Mohammad Ali Shokrgozar, Ali Akbar Saboury
Summary: A novel targeted, trackable, and pH-responsive drug delivery system based on glucoseamine conjugated graphene quantum dots was developed for breast cancer cell-targeted therapy. Fluorescence microscopy and flow cytometry confirmed higher cellular internalization and cytotoxicity of the targeted nanocarrier compared to the non-targeted one.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Reza Khaleghi Abasabadi, Abbas Ali Khodadadi, Yadollah Mortazavi
Summary: The study explores the impact of different types of carbon-nitrogen bonds on the activity and selectivity of the palladium active phase in the hydrogenation of cinnamaldehyde. Pyridinic nitrogen has a positive effect on the uniform distribution of Pd. The catalyst treated at 500 degrees Celsius shows high conversion and selectivity in the reaction.
RESEARCH ON CHEMICAL INTERMEDIATES
(2021)
Article
Engineering, Chemical
Mijin Kim, Jens-Uwe Repke, Reinhard Schomaecker, Abbas Ali Khodadadi, Guenter Wozny, Oliver Goerke, Hamid Reza Godini
Summary: A pseudo-homogeneous model was used to represent the thermal reaction performance of an oxidative coupling of methane (OCM) packed-bed catalytic reactor, taking into account the axial and radial heat and mass transfer characteristics. The model-based analysis was supported by extensive experimentation, aiming to differentiate the direct contribution of catalytic reactions and indirect contribution of the reactor's structural characteristics on the overall OCM reactor performance.
CHEMICAL ENGINEERING & TECHNOLOGY
(2022)
Article
Thermodynamics
Mohammad Saleh Khodaparasti, Mohammad Reza Shirazvatan, Omid Tavakoli, Abbas Ali Khodadadi
Summary: Co-pyrolysis of microalgae Chlorella vulgaris and municipal sewage sludge was studied in a fixed-bed reactor to investigate the effects of temperature, mixing ratio, and Argon flow rate on pyrolysis products. The process was optimized using response surface methodology, and artificial neural network models were developed to simulate and predict pyrolysis yields. The study found that the mixing ratio had the most significant impact on bio-oil yield, while temperature had the highest influence on both biochar and biogas efficiency. The results demonstrate the potential for co-pyrolysis of microalgae and sewage sludge as a sustainable waste-to-energy conversion process.
ENERGY CONVERSION AND MANAGEMENT
(2022)
Article
Environmental Sciences
Zahra Eshaghi Gorji, Abbas Ali Khodadadi, Siavash Riahi, Timo Repo, Yadollah Mortazavi, Marianna Kemell
Summary: In this study, a series of organic compounds were immobilized on N-doped graphene quantum dots to prepare a multifunctional organocatalyst for the coupling reaction between CO2 and propylene oxide. The proposed catalysts demonstrated high activity and yielded excellent results under optimal conditions.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Chemistry, Physical
Fatemeh Gashoul Daresibi, Abbas Ali Khodadadi, Yadollah Mortazavi, Simo Huotari, Mikko Ritala
Summary: This study focuses on the CO2-oxidative dehydrogenation of propane (CO2-ODHP) using CrOx/SiO2 catalyst synthesized through atomic layer deposition (ALD) technique. The ALD catalysts exhibited higher acidity and reducibility compared to impregnation catalysts, as well as better dispersion of chromium oxide particles. The CO2-ODHP reactions using the ALD catalysts demonstrated improved propane conversion and propylene yield.
MOLECULAR CATALYSIS
(2022)
Article
Chemistry, Analytical
Mehrdad Asgari, Fahimeh Hooriabad Saboor, Seyed Parsa Amouzesh, Martin Watt Coull, Abbas Ali Khodadadi, Yadollah Mortazavi, Takeo Hyodo, Yasuhiro Shimizu
Summary: SiO2/ZnO core/shell sensors were synthesized using ultrasonic-assisted deposition-precipitation method. The addition of silica as the core material enhanced the selectivity, stability, and reversibility of the sensors.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Physical
Fatemeh Gashoul Daresibi, Abbas Ali Khodadadi, Yadollah Mortazavi
Summary: Ga2O3 was synthesized on a gamma-Al2O3 support using the atomic layer deposition method (ALD) for the CO2-oxidative dehydrogenation of propane (CO2-ODHP). The Ga loading was controlled by the number of ALD cycles, ranging from 1 to 2.9 wt%. The ALD catalysts exhibited higher activity and selectivity in the CO2-ODHP reaction compared to catalysts prepared with impregnation method, attributed to the higher surface total moderate acidity, Ga-O-Al linkages, and Ga2O3 dispersion. The ALD-3C catalyst, with 2.9% Ga loading, achieved 38% conversion and 82% selectivity to propylene after 120 minutes of CO2-ODHP reaction at 600 degrees Celsius, corresponding to a 96% improvement in propylene yield.
APPLIED CATALYSIS A-GENERAL
(2023)
Article
Chemistry, Physical
Hamide Mohammad Aliha, Abbas Ali Khodadadi, Yadollah Mortazavi, Mohammad Nader Lotfollahi
Summary: The aim of this study is to investigate a new method of fabricating SnO2/polyaniline (PAni) nanocomposite sensors for detecting ammonia at room temperature. The synthesis of PAni is conducted through oxidative polymerization, and SnO2/PAni hybrid nanocomposites with varying percentages of polymer are fabricated using a deposition-precipitation method in the presence of SnCl4 solution. XRD, BET, FTIR, Raman, TGA, and FESEM tests are carried out to characterize the produced powders. The results show that increasing the PAni content in the nanocomposites leads to a decrease in SnO2 crystallite size, an increase in surface area, and improved thermal stability. The SnO2/8 wt% PAni exhibits the highest sensitivity, with a response of approximately 187% for 100 ppm NH3 at room temperature. The optimal heteronucleation and decoration of SnO2 on the PAni surface enhance the sensor's response. Additionally, the sensor demonstrates selectivity in the presence of interfering gases such as CO, ethanol, methane, toluene, and trichloroethylene.
APPLIED SURFACE SCIENCE
(2023)
Article
Business
Mohammad Saleh Khodaparasti, Reza Khorasani, Omid Tavakoli, Abbas Ali Khodadadi
Summary: The effect of co-pyrolysis of municipal sewage sludge (MSS) and microalgae Chlorella Vulgaris (MCV) on pyrolysis products and synergistic effects was investigated. Changes in gas components at different temperatures and reaction times were analyzed using GC analysis. The co-pyrolysis bio-oil was found to be rich in fatty acids and amides compounds, providing a new direction for the high value-added utilization of biomass.
JOURNAL OF BUSINESS RESEARCH
(2023)
Article
Chemistry, Physical
S. Samaneh Bahrani, Abbas Ali Khodadadi, Yadolah Mortazavi
Summary: It has been found that selective deposition of NiO on MoOx/?-Al2O3 enhances the formation of active NiMoS catalytic phase, leading to improved hydrodesulfurization activity. Catalysts prepared by selective atomic layer deposition (S-ALD) showed higher desulfurization conversions at lower reaction temperatures and pressures compared to those prepared by impregnation. HR-TEM and XPS characterization revealed that the enhanced activity of S-ALD catalysts is attributed to the formation of more active NiMoS catalytic phase with higher sulfidability than their impregnation counterparts.
APPLIED SURFACE SCIENCE
(2023)
Article
Engineering, Environmental
Nasim Afzali, Mostafa Torka Beydokhti, Abbas Ali Khodadadi, Yadollah Mortazavi
Summary: In this study, flower-like Ni-doped SnS2 was synthesized using a hydrothermal method, and its oxidation extent was controlled by air oxidation. The results showed that partial oxidation increased the surface area of SnS2 and enhanced its photocatalytic activity. Tuning the oxidation extent and Ni doping can regulate the band gap and defect recombination rate of heterostructures. The Ni-doped 0.34 wt% SnS2 with 43% oxidation showed the highest photocatalytic conversion.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
