Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathway

A Methylation-Phosphorylation Switch Determines Sox2 Stability and Function in ESC Maintenance or Differentiation

(2014) Lan Fang et al.   MOLECULAR CELL

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

(2014) D. Barsyte-Lovejoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress

(2013) Francisca Vazquez et al.   CANCER CELL

Control of the Hippo Pathway by Set7-Dependent Methylation of Yap

(2013) Menno J. Oudhoff et al.   DEVELOPMENTAL CELL

Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability

(2013) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes

(2012) Claude A. Piantadosi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Distinguishing Hyperglycemic Changes by Set7 in Vascular Endothelial Cells

(2012) Jun Okabe et al.   CIRCULATION RESEARCH

Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death

(2012) Qi Xie et al.   EMBO REPORTS

The Nrf2-antioxidant response element pathway: a target for regulating energy metabolism

(2012) Emilie E. Vomhof-DeKrey et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway

(2011) Miao Yu et al.   CELLULAR SIGNALLING

Acetylation-Deacetylation of the Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-related Factor 2) Regulates Its Transcriptional Activity and Nucleocytoplasmic Localization

(2011) Yumiko Kawai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53-Dependent Transcription and Tumor Suppression Are Not Affected in Set7/9-Deficient Mice

(2011) Bernhard Lehnertz et al.   MOLECULAR CELL

The Methyltransferase Set7/9 (Setd7) Is Dispensable for the p53-Mediated DNA Damage Response In Vivo

(2011) Stefano Campaner et al.   MOLECULAR CELL

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

(2011) Deniz Simsek et al.   NATURE

Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1)

(2011) Xiangyu Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells

(2010) Charalambos Michaeloudes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Nrf2-regulated PPARγ Expression Is Critical to Protection against Acute Lung Injury in Mice

(2010) Hye-Youn Cho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epigenetic Histone Methylation Modulates Fibrotic Gene Expression

(2010) G. Sun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lysine methylation regulates the pRb tumour suppressor protein

(2010) S Munro et al.   ONCOGENE

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

(2010) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Oxygen Tension Modulates Acetaminophen-Induced Mitochondrial Oxidant Stress and Cell Injury in Cultured Hepatocytes

(2010) Hui-Min Yan et al.   TOXICOLOGICAL SCIENCES

Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response

(2009) Z. Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of NF-κB activity through lysine monomethylation of p65

(2009) Chee-Kwee Ea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

(2009) P.-O. Esteve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1

(2008) Claude A. Piantadosi et al.   CIRCULATION RESEARCH

IN VITRO MODELING OF HUMAN ALVEOLAR MACROPHAGE SMOKE EXPOSURE: ENHANCED INFLAMMATION AND IMPAIRED FUNCTION

(2008) Aaron R. Winkler et al.   EXPERIMENTAL LUNG RESEARCH

Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory Genes

(2008) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

(2008) Assam El-Osta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase

(2008) Krithika Subramanian et al.   MOLECULAR CELL

Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo

(2008) Julia K. Kurash et al.   MOLECULAR CELL

The role of exercise and PGC1α in inflammation and chronic disease

(2008) Christoph Handschin et al.   NATURE