Review
Chemistry, Multidisciplinary
Tushar Kant, Kamlesh Shrivas, Ankita Tejwani, Khushali Tandey, Anuradha Sharma, Shashi Gupta
Summary: This review provides a comprehensive overview of portable colorimetric chemical sensing devices and their applications in clinical, environmental, and food safety domains. It covers different types of devices, such as handheld, RGB-based, paper-based, and wearable, and explores the underlying principles, functional materials, and detection mechanisms.
Article
Engineering, Environmental
Ping Zheng, Zhiyuan Cui, Haichao Liu, Wenjuan Cao, Feng Li, Ming Zhang
Summary: In this study, two donor-acceptor type small organic fluorescent molecules (T1 and T2) based on the terpyridine group were synthesized and characterized for colorimetric/fluorometric dual-channel probe towards diethylchlorophosphate (DCP). The sensors showed high selectivity, sensitivity, and recyclability in both solution and gas phase, with different response mechanisms attributed to the electron-donating substituents on T1 and T2. The sensing mechanism was further supported by NMR spectra and calculations. Additionally, filter paper strips constructed with T1 and T2 were developed for real-time, on-site monitoring of DCP vapor with high selectivity and sensitivity.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Brian C. Hauck, Brian S. Ince, Patrick C. Riley
Summary: Chemical weapons pose a continuous threat and require improved detection technologies, especially in the absence of new technologies. Lower detection limits can provide early warning and enable rapid countermeasure deployment. This study evaluated colorimetric gas detection tubes for sarin and sulfur mustard warfare agents, determining their limits of detection using active chemical agent. Results showed detection limits of 0.0046 ± 0.0002 and 2.1 ± 0.3 mg/m(3) for sarin and sulfur mustard, respectively. The response of the sulfur mustard detection tube to active agent was weaker compared to the simulant used during development, impacting their real-world detection capabilities.
Article
Nanoscience & Nanotechnology
Seongyeop Lim, Sanghwan Park, Seung Min Moon, Jin Yoo, Jae Hong Choi, Jin Hyun Park, Seongwoo Lee, Hyegi Min, Yun-Tae Kim, Cheongha Lee, Seungmin Kang, Yoon Jeong Jang, Moonsik Shin, Han Yong Bae, Chang Young Lee
Summary: This study presents a colorimetric paper that can detect and identify chemical warfare agents in both liquid and gas phases by inkjet printing carbon nanotube-based chemiresistors on the paper. The printed carbon nanotubes generate unique electrical signals for liquid-phase chemical warfare agents without affecting the colorimetric responses, enabling accurate analyte identification. The study also demonstrates the fabrication of a gas sensor array on the paper using inkjet printing, allowing the identification of CWA simulants based on response patterns.
ACS APPLIED NANO MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Vinod Kumar, Heejeong Kim, Bipin Pandey, Tony D. James, Juyoung Yoon, Eric V. Anslyn
Summary: Chemical warfare agents are a major threat to humanity, peace, and social stability. Recent advancements in supramolecular chemistry, analytical chemistry, and molecular sensors have greatly improved our ability to detect and quantify these agents. Fluorescent and colorimetric chemosensors have emerged as attractive tools for selective, sensitive, cheap, portable, and real-time analysis of chemical warfare agents. This review provides a detailed discussion on molecular sensors used for detecting different classes of agents, as well as the current technology and protocols employed by military forces.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Analytical
Qian Chen, Yudie Sun, Shengjun Liu, Jian Zhang, Cheng Zhang, Hui Jiang, Xinya Han, Lifang He, Suhua Wang, Kui Zhang
Summary: Organophosphorus compounds, including nerve agents and pesticides, are toxic organic phosphorus molecules with significant applications in agriculture and detection. Colorimetric and fluorescence sensors have been widely studied for rapid, sensitive, and convenient detection of organophosphorus analogs.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Materials Science, Multidisciplinary
Daoye Zheng, Yao Wen, Xiaocan Xu, Yu-Sheng Lin
Summary: We propose and demonstrate a metamaterial grating sensor composed of gold nanograting on a silver thin-film and encapsulated with a PDMS microfluidic chip. The sensor is sensitive to the wavevector of incident light and exhibits angle-dependent reflection spectra, with resonance peaks showing blue-shifts when isopropyl alcohol and deionized water solutions are injected. The reflected color also changes with different solutions in the ambient light environment.
MATERIALS TODAY PHYSICS
(2023)
Article
Chemistry, Analytical
Jianping Guan, Jiao Yang, Yue Zhang, Xiaoxue Zhang, Huajuan Deng, Juan Xu, Jinyi Wang, Mao-Sen Yuan
Summary: The ongoing poisoning of agricultural products has made security a major concern, with pesticide residue exceeding standard rates being the main issue. There is an urgent need for monitoring and developing sensitive detection systems for pesticide residues.
Article
Chemistry, Physical
Hasnain Sajid, Khurshid Ayub, Tariq Mahmood
Summary: This study demonstrates the use of monocyclic C-18 and B(9)N(9) as active materials for sensing and removing chemical warfare agents. The sensitivities and adsorption capacities of these materials towards formaldehyde, phosgene, and thiophosgene are thoroughly characterized. The results show that B(9)N(9) exhibits favorable adsorption energies for these molecules compared to C-18.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Analytical
Daniel J. Van Buren, Thomas J. Mueller, Christopher J. Rosenker, John A. Barcase, Kelly A. Van Houten
Summary: The study focused on thermal decomposition of a chemical warfare agent simulant using a custom built pyrolyzer. The experiments aimed to design a simple pyrolyzer that meets safety and security requirements for consistent data collection. Results showed that the activation energy for TEP decomposition was determined to be 32.0 +/- 7.6 kcal/mol, consistent with previous literature data.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2021)
Article
Biochemical Research Methods
Shuai Liu, Jingkai Zhao, Junfeng Wu, Ling Wang, Jiandong Hu, Shixin Li, Hao Zhang
Summary: A deep learning-enabled smartphone platform was developed for fast and highly sensitive detection of dimethoate pesticide. The colorimetric detection method based on color change was used, and a convolutional neural network model was established for self-learning and prediction. The app enabled offline detection in real environments within 15 minutes.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Huimin Hao, Jian Zhu, Bin Yang, Li Peng, Shuyan Lou
Summary: In this study, stable, effective, sensitive, and selective colorimetric detection of carbaryl was achieved using Au@Ova nanoparticles as a nanoprobe. The Au@Ova nanoparticles showed unique colloidal stability in various complex media and exhibited efficient responses to carbaryl. The nanoprobe also demonstrated good selectivity and was successfully applied in the analysis of real samples.
Article
Optics
Xuan Chen, Min Li, Wenchao Chen, Haochen Yang, Zhicheng Pei, Er-Ping Li, Hongsheng Chen, Zuojia Wang
Summary: This study reveals a nontrivial phase modulation mechanism that achieves dispersionless reflection and controllable phase retardation by tilting arranged electric dipoles, breaking the efficiency and bandwidth limitation in electric dipolar resonances in mesoscopic structures.
LASER & PHOTONICS REVIEWS
(2022)
Article
Chemistry, Applied
Jiayin Zhao, Molin Qin, Jiawen You, Ke Liu, Liping Ding, Taihong Liu, Jinglin Kong, Yu Fang
Summary: A chemical approach based on the squaraine-ethanolamine (SQ-ETA) adducts has been developed for rapid and sensitive detection of G-series nerve agents and simulants. The method features turn-on response and colorimetric mode, and can be used for semi-quantitative evaluation with the help of smartphone-based analytical methodology.
Article
Chemistry, Analytical
Mei Li, Shuang Wang, Chuting Xu, Huiwen Ruan, Weiguo Wang, Chuang Chen, Haiyang Li
Summary: A parallel coupling apparatus combining ion mobility spectrometry and ion trap MS (p-IMS-ITMS) was developed to enhance the detection rate and time response capability of a stand-alone ITMS system for efficient chemical tracking.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)