Article
Chemistry, Analytical
Pravanjan Malla, Guan-Cheng Chen, Hao-Ping Liao, Chi-Hsien Liu, Wei-Chi Wu
Summary: An immunosensor utilizing SPCE modified with nanocomposite was developed for PTH detection, showing promising sensitivity and low detection limits for impedimetric and amperometric methods. The sensor has the potential to be used as an electrochemical immunoassay platform for rapid PTH analysis in serum.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Ananya S. Agnihotri, C. G. Ann Maria, Anitha Varghese, Pratap Mane, Brahmananda Chakraborty, M. Nidhin
Summary: In this study, an innovative and cost-effective electrochemical sensor was fabricated for the determination of tacrolimus in pharmaceutical samples. The sensor showed good sensitivity, selectivity, reproducibility, and stability. Extensive density functional theory simulations were carried out to support the experimental findings. This sensor is the first to report the interaction of cobalt ferrite nanoparticles with tacrolimus at the electrode/electrolyte interface.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Supakeit Chanarsa, Jaroon Jakmunee, Kontad Ounnunkad
Summary: A bi-functional material based on silver nanoparticles-reduced graphene oxide composite was successfully synthesized for the construction of a label-free electrochemical immunosensor. The material showed good conductivity/electroreactivity and could generate an analytical response for the detection of human immunoglobulin G. Detection of IgG in human serum using the immunosensor displayed satisfactory accuracy and the potential for further development in clinical diagnosis.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Analytical
Andres F. Cruz-Pacheco, Jennifer Quinchia, Jahir Orozco
Summary: A label-free nanoimmunosensor based on p53/CeO2/PEDOT nanobiocomposite-decorated screen-printed gold electrodes has been developed for the electrochemical detection of anti-p53 autoantibodies. This sensor offers high specificity, selectivity, and long-term storage stability and has the potential to detect anti-p53 autoantibodies in serum samples.
Article
Chemistry, Analytical
Ya-Shin Yeh, Yi-Kuang Yen, Ragurethinam Shanmugam
Summary: This study developed a cost-efficient, disposable, and highly sensitive paper-based electrochemical biosensor that can detect the concentration of interferon-gamma (IFN-?), which is related to Tuberculosis. It has the potential to assist in disease diagnosis.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Applied
Kuan-Wei Huang, Bo-Wei Huang, Hsuan-Tong Chen, Shao-Chen Lu, Hsiu-Hui Chen
Summary: This article presents a method for preparing a multicomponent superomniphobic coating that can be spray-applied onto various substrates, and exhibits low contact angle hysteresis for most liquids. It has a wide range of applications.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Biochemical Research Methods
Marta Lafuente, Fernando Almazan, Eduardo Bernad, Ileana Florea, Raul Arenal, Miguel A. Urbiztondo, Reyes Mallada, Maria P. Pina
Summary: To address the capability gaps in real-time detection and monitoring of neurotoxic gases, this work develops robust and reusable SERS microfluidic chips. The chips, integrated with a 3D plasmonic architecture, demonstrate excellent performance in the label-free detection and monitoring of 2.5 ppmV gaseous DMMP.
Article
Biochemistry & Molecular Biology
Pankaj Kumar, Niloy Sarkar, Amit Singh, Mahima Kaushik
Summary: Silica nanoparticles (SiNPs) were synthesized using condensation method and further surface functionalized with 3-aminopropyltetraethoxysilane (APTES) to form bioactive conjugates. These nanoparticles were characterized using various techniques and their effects on bovine trypsin were studied. SiNPs destabilize the trypsin structure, while SiNPs@APTES provide stabilizing effect and act as an activator for trypsin. These findings suggest that SiNPs and SiNP@APTES can regulate trypsin activity in biomedical applications.
PROCESS BIOCHEMISTRY
(2023)
Article
Chemistry, Physical
Xinrong Huang, Manqing Ge, Huiyan Wang, Han Liang, Na Meng, Ninglin Zhou
Summary: Functionalization of polydimethylsiloxane nanocomposites with advanced nanostructure materials can lead to significant improvements in mechanical and antimicrobial properties. This research presents a creative and easy technique for incorporating silver nanoparticles-lecithin modified montmorillonite into PDMS nanocomposites for antibacterial applications.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Engineering, Environmental
Guangli Li, Xiaoman Qi, Jingtao Wu, Lijian Xu, Xuan Wan, Ying Liu, Yuwei Chen, Qing Li
Summary: A novel label-free molecularly imprinted polymer (MIP) voltammetric sensor was developed for the efficient and selective detection of trace norfloxacin (NOR), which is of great significance for food safety and environmental protection.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Polymer Science
Maria Minodora Marin, Ioana Catalina Gifu, Gratiela Gradisteanu Pircalabioru, Madalina Albu Kaya, Rodica Roxana Constantinescu, Rebeca Leu Alexa, Bogdan Trica, Elvira Alexandrescu, Cristina Lavinia Nistor, Cristian Petcu, Raluca Ianchis
Summary: Natural polysaccharides are recommended for medical applications due to their low cytotoxicity and hydrophilicity. Polysaccharides can be used in additive manufacturing to achieve various customized 3D structures. In this study, silica nanoparticles were added to a microbial polysaccharide to obtain printable hydrogel nanocomposites.
Article
Energy & Fuels
Youkang Yin, Yufei Gao, Liyuan Wang, Lei Zhang, Tianzhao Pu
Summary: Through establishing a mathematical model and conducting experimental verification, this research analyzed the influence of different parameters in diamond wire sawing process. It was found that reducing the workpiece feed speed or increasing the saw wire movement speed is more conducive to obtaining a crack-free sawn surface, with the latter playing a greater role in affecting the surface quality of the sawn surface.
Article
Chemistry, Multidisciplinary
Aekkaphon Mokkarat, Senee Kruanetr, Uthai Sakee
Summary: One-step continuous flow synthesis was developed for the preparation of amino propyl silica-coated nanoparticles, offering advantages such as easy scalability, convenient production, and easy control.
JOURNAL OF SAUDI CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Dmitry A. Migulin, Julia Rozanova, Vasily A. Migulin, Georgy Cherkaev, Ivan B. Meshkov, Alexey A. Zezin, Aziz M. Muzafarov
Summary: In this study, two new types of polymers were synthesized and characterized for their ability to stabilize ultra-small silver nanoparticles and efficiently modify chemical surfaces. The size and distribution of the silver nanoparticles were controlled through a chemically assisted radiation process. The developed functional polymers have important applications in the preparation of nanocomposite coatings.
Article
Automation & Control Systems
Tianzhao Pu, Yufei Gao, Tianliang Hu, Chunfeng Yang
Summary: This paper studies the movement characteristics of cutting coolant and free SiC abrasives in the sawing area when using fixed abrasive diamond wire to cut polysilicon. By establishing a three-dimensional model and analyzing various influencing factors, the change of concentration peak of free abrasives in the cutting coolant is obtained, and methods to enhance the lapping effect of free SiC abrasives on the as-sawn wafer surface are proposed.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)