Article
Engineering, Environmental
Jesse Nii Okai Amu-Darko, Shahid Hussain, Qiang Gong, Xiangzhao Zhang, Ziwei Xu, Mingsong Wang, Guiwu Liu, Guanjun Qiao
Summary: In this study, In2O3/PANI composites were synthesized using the hydrothermal technique to explore their sensing capabilities for NO2 gas. The gas sensing properties, such as response/recovery time, optimal temperature, and recyclability, were investigated by analyzing the morphology, purity, and crystal structures of the samples. The In2O3/PANI-1 sensors exhibited high responses, quick response and recovery times, and a low detection limit to NO2 gas at a working temperature of 250 degrees C. The fundamental detecting mechanism for NO2 gas and the electrical characteristics of the In2O3/PANI composites were also discussed.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Analytical
Tanji Yin, Hemin Wang, Jinghui Li, Baiqing Yuan, Wei Qin
Summary: This study presents an amperometric signal readout strategy based on H2O2 for ISEs, which provides satisfactory slope sensitivity and detection limit compared to potentiometric responses. The method is applicable for sensitive and selective detection of cations and anions.
Article
Chemistry, Multidisciplinary
Wonbin Ju, Sungbae Lee
Summary: A capacitive NO2 sensing device based on graphene was developed using the quantum capacitance effect. The graphene field-effect transistor (G-FET) device had enhanced geometrical capacitance through an aluminum back-gate electrode with a naturally oxidized aluminum surface as an insulating layer. The quantum capacitance and measured capacitance of the device changed with NO2 concentrations, demonstrating the feasibility of capacitive NO2 sensing using graphene and explaining the operational principle.
Article
Engineering, Environmental
Chaohan Han, Xiaowei Li, Yu Liu, Xinghua Li, Changlu Shao, Jisong Ri, Jiangang Ma, Yichun Liu
Summary: A room-temperature NO2 sensor with greatly enhanced sensitivity and rapid response/recovery speed under ultraviolet (UV) illumination has been proposed. The sensor based on In2O3/ZnO yolk-shell nanofibers exhibits remarkable sensitivity and quick response/recovery time, outperforming the performance in dark conditions. These results were attributed to the improved photo-generated charge separation efficiency and increased reactive sites and gas adsorption provided by the heterojunction effect of In2O3/ZnO yolk-shell nanofibers.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Yanna Liu, Sheng Li, Song Xiao, Ke Du
Summary: By loading silver particles on the surface of In2O3 microtubes, the NO2 sensing performance can be improved, with higher response and shorter response/recovery time at room temperature.
Article
Chemistry, Analytical
Yanna Liu, Sheng Li, Shijun Meng, Song Xiao, Hua Song, Ke Du
Summary: In this study, ultrathin two-dimensional graphitic carbon nitride nanosheets and indium oxide nanoparticles were successfully integrated, resulting in optimized composites with outstanding gas sensing properties. The composites exhibited excellent NO2 response, low detection limit, short response/recovery time, and satisfactory selectivity to NO2 at room temperature. The gas sensing mechanism was proposed and verified, showing that the remarkable gas sensing properties were attributed to the combination of heterojunction, enhanced specific surface, and enriched defects.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Physical
Zhicheng Cai, Jiho Park, Sunghoon Park
Summary: A series of porous Au nanoparticles (NPs) decorated with In2O3 nanoparticles (NPs) was embedded in ZnO nanofibers (NFs) using electrospinning and calcination methods. The gas-sensing properties of the resulting sensors were evaluated and it was found that the addition of In2O3 improved the response properties. The sensor with 0.03 g In(NO3)3 (S2) showed excellent stability, selectivity, and a high response to NO2 gas under UV irradiation at room temperature.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Analytical
Qiumei Wang, Chenyu Wang, Xiao Chang, Xianghong Liu, Jun Zhang
Summary: By depositing Pd and Rh metals on porous In2O3 thin films using ALD technology, high and fast response to NO2 at room temperature was achieved. The Pd/Rh catalysts greatly improved the interaction and charge transfer between In2O3 and NO2.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Physical
Manjeet Kumar, Vishwa Bhatt, Joondong Kim, Ju-Hyung Yun
Summary: A highly crystalline In2O3 octahedron was synthesized in this article, with optimal operating conditions identified for gas sensing characteristics, particularly for NO2 detection. This study suggests that the In2O3 octahedron sensor shows promise for future integration with electronic devices.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Multidisciplinary
Zishuo Li, Chengming Lou, Guanglu Lei, Guocai Lu, Hongyin Pan, Xianghong Liu, Jun Zhang
Summary: Metal oxide semiconductor heterostructures are promising for gas sensors due to their unique chemical and electronic properties at the heterointerface. In this study, a highly sensitive and selective NO2 gas sensor based on In2O3/ZnO heterogeneous nanospheres designed by atomic layer deposition (ALD) was reported. ZnO ALD significantly improves the sensor performance of In2O3 nanospheres, with the best response achieved at 180 degrees C operating temperature. The excellent sensor performances are attributed to the modulation of electron depletion layers at the In2O3/ZnO heterointerface, offering insights for designing new materials for detecting hazardous gas molecules.
Article
Nanoscience & Nanotechnology
Jiayue Xie, Xianghong Liu, Shuliang Jing, Chao Pang, Qingshan Liu, Jun Zhang
Summary: Designing a unique NiO-functionalized macroporous In2O3 thin film by atomic layer deposition (ALD) enables high sensitivity to NO2 at low temperatures. Manipulating the oxygen vacancy concentration and p-n heterojunctions in the In2O3/NiO hybrid films significantly impacts the surface chemical and electrical properties of the sensing films. The optimized In2O3/NiO film sensor exhibits a high response to 10 ppm NO2 at 145 degrees C with an ultralow detection limit due to the paramount surface active sites and high carrier concentration enabled by the oxygen vacancies.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Applied
Dasari Sunil Gavaskar, P. Nagaraju, M. V. Ramana Reddy
Summary: Oxygen vacancies, oxidation, and chemisorbed oxygen play crucial roles in the gas-sensing properties of metal oxide semiconductors. To enhance the gas-sensing performance, an effective method to improve chemisorbed oxygen on the material surface is needed. In this study, mesoporous In2O3 and RuO2-In2O3 nanocomposite porous structured thin films were prepared using the spray pyrolysis technique. The addition of RuO2 increased the chemisorbed oxygen on the film surface. Characterization of the prepared films included XRD, FESEM, AFM, TEM, UV-vis spectrophotometry, photoluminescence, XPS, and BET. The nanocomposite films exhibited high specific surface area and porosity, which favored their gas-sensing properties. Among all the samples, RuO2-In2O3 nanocomposite thin film with 20 wt% RuO2 concentration showed remarkable sensing properties towards 50 ppm benzene at room temperature.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Chemistry, Analytical
Kaikai Wang, Rongning Liang, Wei Qin
Summary: A new protocol for developing sensitive and rapid polymeric membrane polyion sensitive electrodes is explored in this study. The use of a thin membrane configuration effectively blocks the diffusion of polyions and enhances the potential response, offering a significantly improved sensitivity and measurement time compared to traditional potentiometric polyion sensors. The proposed polyion sensing platform shows great promise in sensitive and rapid detection of polyions and other polyion-involved bioanalyses.
ANALYTICAL METHODS
(2022)
Article
Chemistry, Physical
Qiumei Wang, Lihao Zhou, Shaobo Li, Xiao Chang, Xianghong Liu, Jun Zhang
Summary: In this study, In2O3/SnO2 heterostructures were designed using atomic layer deposition (ALD), which regulated the energy band structure and enhanced the electron transfer, resulting in improved adsorption of target gases. The sensors based on In2O3/SnO2 demonstrated outstanding performance at room temperature, with a response of 2900 to 10 ppm NO2 and a detection limit of 61 ppb. Density functional theory (DFT) calculations showed significant enhancement in charge transfer and interaction energy between In2O3/SnO2 and NO2.
APPLIED SURFACE SCIENCE
(2023)
Article
Engineering, Electrical & Electronic
PeiJiang Cao, RongGuan Chen, YongZhi Cai, Dnyandeo Pawar, Ch N. Rao, Shun Han, WangYin Xu, Ming Fang, XinKe Liu, YuXiang Zeng, WenJun Liu, DeLiang Zhu, YouMing Lu
Summary: The study focuses on the gas sensing properties of high oxygen vacancy-rich ultrathin indium oxide nanosheets to low concentration of nitrogen dioxide (NO2), showing benchmarked response and theoretical detection limit at ppb level. The nanosheets exhibit superior sensing characteristics, making them suitable for detecting NO2 at low-temperature.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2021)
Editorial Material
Otorhinolaryngology
J. P. Kuehn, T. Vogt, B. Schick
Article
Chemistry, Multidisciplinary
Chloe A. Fuller, Douglas A. Blom, Thomas Vogt, Ivana Radosavljevic Evans, John S. O. Evans
Summary: Functional oxides with high ionic conductivity have important technological applications. The addition of oxide vacancies and interstitials can enhance ionic conductivity in perovskite-related compounds.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Chloe A. Fuller, James Iain Murrell, Douglas A. Blom, Thomas Vogt, Weiguo Zhang, P. Shiv Halasyamani, Ivana Radosavljevic Evans, John S. O. Evans
Summary: The Ba3-xSrxYGa2O7.5 family of perovskite-related compounds exhibits complex structural evolution and conductivity variations influenced by microstructural effects. Ba-rich samples show mixed proton and oxide ion conductivity in moist atmospheres, while Sr-rich samples act primarily as oxide ion conductors under dry conditions.
CHEMISTRY OF MATERIALS
(2022)
Article
Chemistry, Physical
Partha Pratim Das, Sudeshna Samanta, Sangita Das, Ratnadwip Singha, Thomas Vogt, Yongjae Lee
Summary: FeSbO4 exhibits an extraordinarily high electrical resistance under high pressure, attributed to the increased Coulomb repulsion between iron 3d electrons and changes in the lattice structure leading to a Mott insulating phase transition. The sample maintains its high resistance even after pressure release.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Multidisciplinary Sciences
Seohee Yun, Huijeong Hwang, Gilchan Hwang, Yeongkyoo Kim, Douglas Blom, Thomas Vogt, Jeffrey E. Post, Tae-Yeol Jeon, Tae Joo Shin, Dong-Zhou Zhang, Hiroyuki Kagi, Yongjae Lee
Summary: This study reveals the presence of super-hydrated birnessite, known as buserite, in manganese nodules found on the ocean floor. Buserite remains stable up to depths of 70 km before transforming into manganite. The subsequent transformations to hausmannite and pyrochroite occur at depths of approximately 100 km and 120 km, respectively, accompanied by a reduction in the oxidation state of manganese. These findings provide insights into the geochemical cycle of manganese minerals in subduction and other aqueous terrestrial environments, and have implications for water storage and cycling.
NATURE COMMUNICATIONS
(2022)
Correction
Dermatology
Thomas Vogt
AKTUELLE DERMATOLOGIE
(2022)
Review
Oncology
Joerg Reichrath, Winfried Maerz, Frank R. De Gruijl, Reinhold Vieth, William B. Grant, Andrzej T. Slominski, Michael F. Holick, Thomas Vogt, Stefan Pilz
Summary: The symposium discussed important new advances in the field of vitamin D in prevention and therapy, including new signaling pathways, biologic effects, and the relevance of vitamin D deficiency to various chronic diseases. It also highlighted the inverse association between vitamin D serum concentrations and COVID-19 infections, morbidity, and mortality. The need for action to address vitamin D deficiency was emphasized, including through food fortification, supplementation, and moderate UV exposure.
ANTICANCER RESEARCH
(2022)
Article
Oncology
Christoforos Christofi, Leandros Lamnis, Alexandra Stark, Heike Palm, Klaus Romer, Thomas Vogt, Joerg Reichrath
Summary: This study found differential regulation of VDR and AHR target genes by UVB and 1,25(OH)2D3 in HaCaT and SCL-1 cells during different stages of skin photo-carcinogenesis. In precancerous HaCaT keratinocytes, UVB treatment significantly enhanced the induction of an AHR-mediated target gene (CYP1A1), while in SCL-1 cells, 1,25(OH)2D3 treatment led to higher expression of CYP1A1. In addition, 1,25(OH)2D3 up-regulated the classical VDR target CYP24A1, but not by UVB.
ANTICANCER RESEARCH
(2022)
Article
Materials Science, Multidisciplinary
Gabriel L. Murphy, Zhaoming Zhang, Helen E. Maynard-Casely, Joshua Stackhouse, Piotr M. Kowalski, Thomas Vogt, Evgeny Alekseev, Brendan J. Kennedy
Summary: A combined experimental and theoretical investigation was conducted to study the compressibility of two SrUO4-x polymorphs (alpha and fi) under hydrostatic conditions. The study explains the contrasting chemical and mechanical behaviors of these polymorphs by differences in oxygen defect formation chemistry. The experimental data and ab initio calculations revealed that the expansion of the uranyl bonds in alpha-SrUO4 and fi-SrUO4 under hydrostatic pressures is due to the reduction of uranium formal oxidation state and the formation of oxygen vacancies. The difference in preferred lattice sites for oxygen defect formation leads to the significant difference in apparent bulk moduli between the two polymorphs.
Article
Chemistry, Physical
Matilde Saura-Muzquiz, Frederick P. Marlton, Bryce G. Mullens, Jiatu Liu, Thomas Vogt, Helen E. Maynard-Casely, Maxim Avdeev, Douglas A. Blom, Brendan J. Kennedy
Summary: This article examines the Bi3FeMo2O12 system as a rare example of a transition-metal oxide that undergoes a symmetry lowering and a 2:1 ordering of the transition-metal cations upon heating. The structural phase transition between the tetragonal and monoclinic polymorphs was investigated using a combination of X-ray and neutron diffraction data. The results show that the phase transition is first order in nature and occurs at low temperatures. The role of Bi3+ 6s lone pairs in the phase transition and the magnetic behavior of the system were also studied.
CHEMISTRY OF MATERIALS
(2023)
Article
Chemistry, Physical
Jinhyuk Choi, Thomas Vogt, Yongjae Lee
Summary: The research demonstrates that CAU-10-H exhibits different structures and water adsorption/release properties at different pressures. The understanding of the water-MOF interaction from the four different phases provides important insights for designing new materials and utilizing pressure for chemical modifications.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Meeting Abstract
Oncology
Jorg Reichrath, Florian Biersack, Stefan Wagenpfeil, Jakob Schoepe, Claudia Pfoehler, Roman Saternus, Thomas Vogt
ANTICANCER RESEARCH
(2022)
Meeting Abstract
Oncology
Christoforos Christofi, Alexandra Stark, Heike Palm, Thomas Vogt, Joerg Reichrath
ANTICANCER RESEARCH
(2022)
Meeting Abstract
Oncology
Leandros Lamnis, Alexandra Stark, Heike Palm, Thomas Vogt, Joerg Reichrath
ANTICANCER RESEARCH
(2022)
Meeting Abstract
Oncology
Roman Saternus, Marcus Kleber, Winfried Maerz, Thomas Vogt, Joerg Reichrath
ANTICANCER RESEARCH
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)