Article
Biochemical Research Methods
Cheng-Xiao Fan, Jin-Hai Li, Jie-Peng Yao, Jing-Jing Liu, Nan Wang, Lan Huang, Zhong-Yi Wang
Summary: Using PEDOT as the conductive polymer, an innovative small-scale sensor was developed for directly measuring salicylate ions in plants, enabling rapid detection of salicylic acid without complicated pretreatment. The sensor demonstrated excellent miniaturization potential, longer lifespan, robustness, and direct usability for detecting salicylate ions in real samples without additional pretreatment. It exhibited good Nernst slope, a wide linear range, and a low detection limit, making it a reliable tool for in situ measurement of salicylic acid in plants in vivo.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Polymer Science
Hisham S. M. Abd-Rabboh, Abd El-Galil E. Amr, Abdulrahman A. Almehizia, Ayman H. Kamel
Summary: The application of ion-selective electrodes in pharmaceutical analysis has expanded due to their high selectivity, low cost, and sensitivity. All-solid-state potentiometric selective electrodes designed are cost-effective, reliable, and robust, and have been successfully used for pholcodine determination. The sensors exhibit high sensitivity and can be used for fast and low-cost assessment of pholcodine levels.
Article
Chemistry, Analytical
Shiva Pesaran, Elmira Rafatmah, Bahram Hemmateenejad
Summary: The origami three-dimensional paper-based potentiometric sensor is simple to make, highly sensitive, and responsive to different ions. It can also function as a biosensor by adding enzymes. Additionally, it has the advantage of low sample consumption and automatic sampling capabilities.
Article
Biochemistry & Molecular Biology
Hisham S. M. Abd-Rabboh, Heba M. Hashem, Layla M. S. Al Shagri, Abdel El-Galil E. Amr, Abdulrahman A. Almehizia, Ahmed M. Naglah, Ayman H. Kamel
Summary: Novel cost-effective screen-printed potentiometric platforms were designed and characterized for the assessment of Fluoxetine (FLX). The platforms showed near-Nernstian potentiometric response with high sensitivity and low detection limits. They were successfully used for FLX determination in different pharmaceutical dosage forms, providing a portable, rapid, disposable, and cost-effective analytical tool.
Article
Polymer Science
Majed A. Bajaber, Ayman H. Kamel
Summary: A novel disposable all-solid-state desvenlafaxine-selective electrode was created using single-walled carbon nanotubes as an ion-to-electron transducer. The electrode exhibited quick reaction, outstanding stability, and the potential for on-site testing.
Article
Engineering, Electrical & Electronic
Moch. Rifqi Tamara, Danang Lelono, Roto Roto, Kuwat Triyana
Summary: This study explores the feasibility of a taste sensor using an all-solid-state electrode design and a polypyrrole-carbon black composite as an ion-electron transducer. The sensor acts similarly to an all-solid-state electrode in terms of stability improvement with the addition of the polypyrrole-carbon black layer. It exhibits linear behavior toward tannic acid with high sensitivity and selectivity.
SENSORS AND ACTUATORS A-PHYSICAL
(2023)
Article
Chemistry, Analytical
Mahmoud A. Tantawy, Ekram H. Mohamed, Ali M. Yehia
Summary: Flunitrazepam is a commonly used hypnotic drug for incapacitating victims for sexual assault. Miniaturized screen-printed potentiometric sensors with a PEDT nano-dispersion as a conducting hydrophobic polymer have shown favorable results in the determination of flunitrazepam in various beverages. The proposed sensor provides a simple and user-friendly diagnostic tool for on-site determination of flunitrazepam.
Article
Construction & Building Technology
Zhenxing Du, Li Tian, Penggang Wang, Zhaoyi Chen, Dongbo Cui, Zuquan Jin, Hai Zhang
Summary: In this study, an all-solid-state chloride sensor with excellent performance was developed, which has great potential for non-destructively monitoring chloride penetration in concrete structures.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Dharmesh Mishra, Andrew Krause, Harkirat Singh Sahni, Somak Chatterjee
Summary: A functional ionophore (tetramethyl thiuram disulfide or TMTDS) and multi-walled carbon nanotubes (MWCNTs)-based composite paste was prepared by a novel and simple approach, to fabricate a two-electrode system for detection of lead ions in drinking water, by potentiometric method. Homogenous and properly dispersed paste was obtained by blending TMTDS and MWCNTs powder in silicon oil. The working electrode contained the ionophore and the potential between working and reference electrodes were used for assessing performance of the proposed sensor.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Construction & Building Technology
Zhenxing Du, Penggang Wang, Zhaoyi Chen, Dongbo Cui, Zuquan Jin, Hai Zhang
Summary: The all-solid-state pH sensor developed in this study showed excellent performance and potential in monitoring the pH value changes and corrosion process of concrete.
JOURNAL OF BUILDING ENGINEERING
(2022)
Review
Chemistry, Analytical
Jiawei Zhai, Bin Luo, Aixue Li, Hongtu Dong, Xiaotong Jin, Xiaodong Wang
Summary: This paper reviews the development and feasibility of all-solid-state ion-selective electrodes (ASSISEs) for agricultural crop detection, including crop nutrition and heavy metal pollution. The findings suggest that ASSISEs have the potential to be applied in crop detection.
Article
Electrochemistry
Tugba Ozer, Charles S. Henry
Summary: This study developed potassium selective thermoplastic electrodes (TPEs) for potentiometric detection, demonstrating their potential application in accurate detection of potassium ions in biofluids.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Tao Liang, Nan Jiang, Shuqi Zhou, Xinyi Wang, Yingke Xu, Chunsheng Wu, Dmitry Kirsanov, Andrey Legin, Hao Wan, Ping Wang
Summary: This study combined LAPS with ionophore-doped all-solid-state silicone-rubber ISMs to establish a program-controlled multiplexed ISLAPS system for physiological ions detection. The silicone-rubber ISMs have better adhesion to silicon-based sensors without containing plasticizers, which can avoid the plasticizer pollution and improve the long-term stability. Pre-modifying a layer of P3OT on the sensor surface inhibit the formation of an aqueous layer and improve the sensor lifetime.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Ahmed M. Abdel-Raoof, Ahmed Elsonbaty, Sara Abdulwahab, Wafaa S. Hassan, Maya S. Eissa
Summary: Food safety is a crucial concern in the current food-animal industry, and a new sensitive electrode was introduced for rapid and accurate detection of veterinary drugs in chicken meat. The electrode demonstrated high stability, sensitivity, low detection limit, and good reproducibility, with unique advantages in sample preparation and matrix interference.
MICROCHEMICAL JOURNAL
(2021)
Article
Engineering, Electrical & Electronic
Yujing Liu, Juan Yu, Fan Zhang, Pingang He
Summary: An all-solid-state potentiometric aptasensor utilizing signal amplification by polycation was developed for streptomycin detection, demonstrating high sensitivity, good selectivity, and stability. It showed practicality for milk sample detection.
IEEE SENSORS JOURNAL
(2021)
Article
Spectroscopy
Yeming Xu, Pai Liu, Yunhong Zhang
Summary: Water content in atmospheric aerosols is crucial for understanding atmospheric chemistry and addressing environmental issues. FTIR spectroscopy is commonly used to quantify water content, but distortion in the OH stretching vibration band can affect accuracy. A new model for simulating FTIR absorption of water droplets was developed to address this issue.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
Yunxia Wang, Lulu Song, Guangguo Wang, Hongyan Liu, Zhuanfang Jing, Yongquan Zhou, Fayan Zhu, Yunhong Zhang
Summary: The research investigated the existence of direct contact ion pairs (CIP) in magnesium nitrate solutions using Raman spectroscopy, molecular dynamics (MD) simulations, and density functional theory (DFT) calculations. The study revealed that solvent-shared ion pairs (SIPs) were dominant in dilute solutions, gradually transforming into CIPs as the concentration increased. As the concentration further increased, the CIP content decreased while the complexity of structures increased.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Environmental Sciences
Yeming Xu, Pai Liu, Shuaishuai Ma, Wenxiu Pei, Shufeng Pang, Yunhong Zhang
Summary: Understanding the efflorescence process of atmospheric aerosols is crucial for describing their phase transition dynamics. In this study, the efflorescence process of ammonium sulfate aerosol droplets mixed with water-soluble organic compounds (WSOCs) was investigated using ATR-FTIR spectroscopy. It was found that the addition of WSOCs lowers the characteristic efflorescence relative humidity, broadens the range, and reduces the crystallization ratio of the aerosol droplets. Sucrose and glycerol were observed to completely suppress crystallization at specific organic to inorganic ratios, suggesting the possibility of aerosols skipping efflorescence and transitioning into a glassy state at low humidity conditions.
ATMOSPHERIC ENVIRONMENT
(2022)
Article
Environmental Sciences
Na Wang, Yaxin Guo, Jiarong Li, Shufeng Pang, Yunhong Zhang
Summary: Water-soluble amino acids were found to play an important role in cloud condensation nuclei (CCN) material. The hygroscopic properties and phase states of ammonium nitrate (AN) mixed with glycine and alanine were investigated. The study revealed that amino acids could form mixed particles with AN and remain solid during hydration due to hydrogen bonding interaction.
ATMOSPHERIC ENVIRONMENT
(2022)
Article
Soil Science
Taiyan Yuan, Shuo Chen, Yunhong Zhang, Lingmei Ji, Biswanath Dari, Debjani Sihi, Dehua Xu, Zhiye Zhang, Zhengjuan Yan, Xinlong Wang
Summary: This study investigated the effects of APP and MAP on phosphorus transformation in a calcareous soil. The results showed that APP application significantly increased the extractable phosphorus in the soil and altered the distribution of phosphorus forms and microbial community structure. Soil pH was identified as a key factor in explaining these changes.
BIOLOGY AND FERTILITY OF SOILS
(2022)
Article
Environmental Sciences
Li Zhou, Ting Lei, Dongjuan Kang, Yucong Guo, Yunhong Zhang, Fumo Yang, Maofa Ge, Weigang Wang
Summary: Coal-derived fly ash is a major aerosol composition in the atmosphere. The heterogeneous uptake of hydrogen peroxide and sulfur dioxide on coal fly ash was studied, and the effects of temperature and mixing ratio on the uptake coefficients were analyzed. The presence of gaseous H2O2 appeared to enhance the ability of SO2 uptake on coal fly ash.
FRONTIERS IN ENVIRONMENTAL SCIENCE
(2022)
Article
Chemistry, Analytical
Baokun Huang, Qiannan Zhao, Chenglin Sun, Lin Zhu, Hong Zhang, Yunhong Zhang, Cunming Liu, Fabing Li
Summary: In this study, a simple and effective method was developed to enhance the signal of spontaneous Raman scattering from gases and liquids. By utilizing the principle of an integrating sphere, multiple pass actions of low-energy pump light and the collection of all Raman scattered light were achieved. The experimental results showed that our setup can significantly improve the detection limit for liquids compared to confocal Raman scattering spectroscopy.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Xinbo Jing, Zhe Chen, Qishen Huang, Pai Liu, Yun-Hong Zhang
Summary: This study reports a technique for high spatiotemporal resolution pH measurement in microdroplets using spontaneous Raman spectroscopy. The results show that chloride depletion in the microdroplets leads to a continuous increase in pH, while a stable pH gradient exists within a single droplet. This technique provides a new method for precise pH measurement in aerosols.
ANALYTICAL CHEMISTRY
(2022)
Article
Environmental Sciences
Yue Zhu, Shufeng Pang, Yunhong Zhang
Summary: The phase state of atmospheric aerosols has significant impacts on global climate and atmospheric environment chemistry. Recent studies have shown that there is an unexpected phase transition of NaCl and (NH4)(2)SO4 when they are mixed with ultraviscous gluconic acid. The slower water diffusion in the mixed particles caused by the ultra-viscous property of gluconic acid leads to efflorescence upon hydration.
ATMOSPHERIC ENVIRONMENT
(2022)
Article
Engineering, Environmental
Zhe Chen, Pai Liu, Hang Su, Yun-Hong Zhang
Summary: Depletion of chloride, nitrate, or ammonium from atmospheric aerosols represents a unique class of displacement reactions, which can significantly modify the composition of aerosols and perturb the atmospheric cycle of volatile compounds. The study elucidated the thermodynamics and kinetics of these reactions, revealing lower effective dissociation constants and rapid kinetics in aerosol microdroplets. These findings suggest the importance of understanding the unique displacement reactions for predicting the properties of atmospheric aerosols.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Review
Meteorology & Atmospheric Sciences
Tong Zhu, Mingjin Tang, Meng Gao, Xinhui Bi, Junji Cao, Huizheng Che, Jianmin Chen, Aijun Ding, Pingqing Fu, Jian Gao, Yang Gao, Maofa Ge, Xinlei Ge, Zhiwei Han, Hong He, Ru-Jin Huang, Xin Huang, Hong Liao, Cheng Liu, Huan Liu, Jianguo Liu, Shaw Chen Liu, Keding Lu, Qingxin Ma, Wei Nie, Min Shao, Yu Song, Yele Sun, Xiao Tang, Tao Wang, Tijian Wang, Weigang Wang, Xuemei Wang, Zifa Wang, Yan Yin, Qiang Zhang, Weijun Zhang, Yanlin Zhang, Yunhong Zhang, Yu Zhao, Mei Zheng, Bin Zhu, Jiang Zhu
Summary: In the past 25 years, atmospheric chemistry research in China has grown rapidly, focusing on the concept of air pollution complexity. Over 24,000 papers on air pollution, authored or co-authored by Chinese scientists, were published in 2021. This paper reviews representative studies on various aspects of atmospheric chemistry in China, providing a starting point for understanding the field. The advances discussed in this paper have established a theoretical framework for air pollution, supported effective air pollution control policies in China, and created opportunities for education and career development.
ADVANCES IN ATMOSPHERIC SCIENCES
(2023)
Article
Environmental Sciences
Wen-Xiu Pei, Shuai-Shuai Ma, Zhe Chen, Yue Zhu, Shu-Feng Pang, Yun-Hong Zhang
Summary: This study investigates the heterogeneous uptake of NO2 by sodium acetate droplets under different NO2 concentrations and relative humidity conditions using micro-FTIR. The results show that the uptake coefficient of sodium acetate droplets is influenced by relative humidity and the volatility of acetate esters. Additionally, nitrite formation is observed during the heterogeneous uptake process, providing a new pathway for atmospheric nitrogen cycling and secondary nitrite aerosol formation.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Chemistry, Physical
Xinbo Jing, Zhe Chen, Xue Cao, Qishen Huang, Pai Liu, Yun-hong Zhang
Summary: Sulfate formation from SO2 during urban haze events in China is a complex process with the important contributions of regionally transported sea spray aerosols (SSAs) and transition-metal ions (TMI)-catalyzed reactions. The reaction kinetics of Mn2+-catalyzed SO2 oxidation in NaCl microdroplets were investigated, revealing a linear correlation between reaction rate and droplet radius. The saturation concentration for both Mn2+ and SO2 implied an upper limit for the SO2 uptake coefficient, which increased with high ionic strength but was constant at pH levels of 5 to 8. The uptake coefficient was significantly higher than that of the uncatalyzed autoxidation of SO2 and other mineral dust oxidation pathways.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Environmental Sciences
Xue Cao, Zhe Chen, Yu-Xin Liu, Xin-Bo Jing, Lin-Fang Li, Pai Liu, Yun-Hong Zhang
Summary: Sulfate aerosols are produced at a rapid rate in China's winter haze, and this is believed to be due to the heterogeneous conversion of SO2 in urban aerosols. A study conducted in levitated microdroplets has directly measured the Fe(III)-catalyzed SO2 conversion in aerosols and found that it is 2 to 3 decades faster than in bulk solutions. The reaction rate is proportional to the droplet surface area, indicating that the major reaction occurs at the air-water interface.
ENVIRONMENTAL SCIENCE-ATMOSPHERES
(2023)
Article
Environmental Sciences
Shuaishuai Ma, Qiong Li, Yunhong Zhang
Summary: In this study, the hygroscopic growth and chemical composition evolution of NaNO3 and DCAs mixtures were measured using ATR-FTIR and vacuum FTIR techniques. The results showed that the phase state of NaNO3, chemical composition, water activity, and HNO3 gas-phase diffusion play crucial roles in HNO3 release from nitrate and DCA mixtures.
ATMOSPHERIC CHEMISTRY AND PHYSICS
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
