Article
Chemistry, Multidisciplinary
Angeline S. Dileseigres, Yoann Prado, Olivier Pluchery
Summary: The functionalization of gold nanoparticles with thiol molecules in solution is crucial for their application development. In this study, the changes in localized surface plasmon resonance (LSPR) peak due to the reaction between thiol molecules and gold nanoparticles were investigated using UV-visible spectroscopy. The saturation of thiol molecules on the nanoparticle surface was confirmed, and the wavelength shift was accurately predicted using an analytical model. The kinetics of the functionalization reaction were found to be rapid, completing in less than an hour.
Article
Chemistry, Multidisciplinary
Axel Gomes, Jose M. Carnerero, Aila Jimenez-Ruiz, Elia Grueso, Rosa M. Giraldez-Perez, Rafael Prado-Gotor
Summary: This study investigated the adsorption of lysozyme onto gold nanoparticles and obtained the free energy of binding of the system for the first time. The interactions between lysozyme and AuNPs induce aggregation of citrate-stabilized AuNPs at low concentrations. The study also found that 10 nm AuNPs were the most appropriate for this interaction.
Article
Chemistry, Analytical
Benjamin Charron, Alexandre Delorme, Caroline Dubois, Maryam Hojjat Jodaylami, Jean-Francois Masson
Summary: This study reveals the significant impact of human serum albumin (HSA) on the response and binding constants of sensing assays, while bovine serum albumin (BSA) does not show the same effect. The results also highlight the importance of the matrix protein/analyte/receptor interactions in determining the assay response.
Article
Chemistry, Analytical
Like Li, Ya-nan Zhang, Wanlu Zheng, Xuegang Li, Yong Zhao
Summary: This study proposes an optical fiber SPR biosensor based on a sandwich model with gold nanoparticles amplification for high sensitivity DNA hybridization detection. The experimental results show a log-linear response in the DNA concentration range of 1 pM-10 nM with high sensitivity and detection limit.
Article
Chemistry, Multidisciplinary
Laura Sutarlie, Heng Li Chee, Sian Yang Ow, Zainul Aabdin, Weng Weei Tjiu, Xiaodi Su
Summary: In this study, a rapid method for counting total bacterial cells was developed using gold nanoparticles conjugated with affinity ligands to stain bacteria captured on a filter membrane. The method showed high sensitivity and a short turnover time, making it suitable for on-site applications.
Article
Chemistry, Multidisciplinary
Laura Sutarlie, Heng Li Chee, Sian Yang Ow, Zainul Aabdin, Weng Weei Tjiu, Xiaodi Su
Summary: A rapid total bacterial count method based on gold nanoparticles conjugated with affinity ligands was developed. The method showed high sensitivity and fast response time, making it suitable for on-site applications.
Article
Nanoscience & Nanotechnology
Briliant Adhi Prabowo, Agnes Purwidyantri, Bei Liu, Hsin-Chih Lai, Kou-Chen Liu
Summary: The study investigated the impact of different gold nanoparticle structures on plasmonic enhancement for DNA detection on a few-layer graphene surface plasmon resonance sensor. The use of gold nano-urchins significantly reinforced the overall DNA hybridization signal, reaching the femtomolar range limit of detection. The integrated approach of the graphene-based SPR sensor and GNu-assisted DNA detection provided a proof-of-concept for tuberculosis disease screening in low-resource settings.
Article
Chemistry, Physical
Anderson Valle, Kaline Ferreira, Luiz Goulart, Carmonizia Freire, Eliton Medeiros, Carlos Alberto de Souza Filho, Rossana Cruz, Luciano Rodrigues, Cleumar Moreira
Summary: A smartphone-based surface plasmon resonance (SPR) sensor is proposed for detecting glyphosate, a widely used herbicide, with different pH and concentrations. CuO nanoparticles are added to enhance the detection in diluted glyphosate samples. The sensor shows increased sensitivity in acidic solutions, reaching a dilution of 10^(-8) (v/v) or 5 x 10^(-7) ppm. This device offers high sensitivity, portability, and real-time analysis.
Article
Chemistry, Multidisciplinary
Da Li, Julien Brunie, Fan Sun, Philippe Nizard, Delphine Onidas, Aazdine Lamouri, Vincent Noel, Claire Mangeney, Giorgio Mattana, Yun Luo
Summary: A new generation of SERS security labels based on silver nanoparticles functionalized by aryl diazonium salts with distinguishable Raman fingerprints was developed in this study. The remarkable potential of diazonium salt chemistry to design Ag NPs-based SERS security labels was confirmed through proof-of-concept Raman imaging experiments and their successful application in ink printing.
NANOSCALE ADVANCES
(2022)
Article
Optics
Haiwei Mu, Xinchen Xu, Jingwei Lv, Chao Liu, Wei Liu, Lin Yang, Jianxin Wang, Qiang Liu, Yan Lv, Paul K. Chu
Summary: This study introduces a method that combines the plasmon mode of metal nanoantennas with the anapole mode of high refractive index dielectric materials to increase the electric field strength and minimize energy loss. Through numerical simulation and multipole decomposition analysis, the near-field enhancement features and distributions of the electric field are explored using a silicon disk with slots and two Au rings with a coupling mechanism. By generating high-intensity hot spots inside the disk, the electric field can be significantly enhanced, allowing nearby molecules to directly interact with these hot spots, suggesting significant applications in strong photon-exciton coupling and nonlinear photonics.
Article
Chemistry, Physical
Yunshan Fan, Yara Aceta, Esther Hessong, Athena Bengston, Laris A. Biageyian, Quan P. Huynh, Robert M. Corn
Summary: Diffraction patterns observed in SPRI microscopy measurements of single gold nanorods exhibit complex behavior near the longitudinal plasmonic resonance band, with a unitless ratio parameter M-R created to describe the diffraction pattern distribution. Results show that this behavior only occurs in the anomalous dispersion region, when the laser wavelength used is shorter than the AuNR plasmonic resonance maxima.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Physics, Applied
Kishan Jayanand, Anupama B. Kaul
Summary: The study explores the plasmonic and excitonic interactions in two-dimensional (2D) semiconductors and zero-dimensional (0D) metal nanoparticles, revealing the tunability of the spectral response. The geometry of the hybrid structures affects the surface plasmon resonance (SPR) peaks, leading to a shift in the spectral response of the 2D semiconductor and influencing the carrier dynamics.
APPLIED PHYSICS LETTERS
(2022)
Article
Biochemistry & Molecular Biology
Maciej Trzaskowski, Marcin Drozd, Tomasz Ciach
Summary: This study investigated the attachment process of saccharide particles to cell receptors responsible for glucose transport across the cell membrane. The interactions between simple saccharides, such as glucose and sucrose, and dextran nanoparticles with two species of GLUT proteins were measured. The results showed that polysaccharide nanoparticles interacted with GLUT proteins, and the strengths of interactions varied between proteins.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Pengcheng Gao, Yingying Wei, Qianrui Xu, Yong Jiang
Summary: This study explores a green method to prepare chain-like gold nanoparticle assembly structures using L-cysteine. The L-cysteine acts as a morphology inducer and a template molecule to control the morphology of the nanoparticles and trigger the assembly. The obtained assembly structures exhibit significant absorption in the near-infrared (NIR) region and can be used for photothermal cancer therapy. Coating the assembly with biocompatible mesoporous silica improves biocompatibility and drug delivery ability.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Agnieszka Paziewska-Nowak, Marcin Urbanowicz, Kamila Sadowska, Dorota Genowefa Pijanowska
Summary: The paper describes the development and utility of a novel DNA oligonucleotide-based affinity bioreceptor for lactoferrin. The research investigates the affinity of different types of oligonucleotides to the target protein using surface plasmon resonance method. The selected DNA sequence showed high affinity to lactoferrin and demonstrated its potential as a bioreceptor for lactoferrin determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Physical
Mathias Dolci, Jean-Francois Bryche, Julien Moreau, Cedric Leuvrey, Sylvie Begin-Colin, Gregory Barbillon, Benoit P. Pichon
APPLIED SURFACE SCIENCE
(2020)
Article
Chemistry, Multidisciplinary
Amin Valiei, Nicholas Lin, Jean-Francois Bryche, Geoffrey McKay, Michael Canva, Paul G. Charette, Dao Nguyen, Christopher Moraes, Nathalie Tufenkji
Article
Biophysics
Zhor Khadir, Victor Schmidt, Kevin Chabot, Jean-Francois Bryche, Ulrike Froehlich, Julien Moreau, Michael Canva, Paul Charette, Michel Grandbois
Summary: This study utilizes surface micropatterning techniques to control the adhesion of endothelial cells and establish a well-controlled cell layer phenotype on SPR sensor surfaces. The formation of cell-cell junctions can be controlled by tuning the inter-cellular spacing. The functionality of the proposed model has been confirmed through fluorescence microscopy and SPRI.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Multidisciplinary
Jean-Francois Bryche, Marlo Vega, Agnes Tempez, Thibault Brule, Thomas Carlier, Julien Moreau, Marc Chaigneau, Paul G. Charette, Michael Canva
Summary: This work demonstrates the enhancement in plasmonic sensing efficacy by spatially-localized functionalization on nanostructured surfaces, where probe molecules are concentrated in areas of high field concentration. SERS measurements on nanostructured surfaces with homogeneous and spatially-localized functionalization with thiophenol show that the Raman signal mainly originates from high field concentration areas. TERS measurements with 10 nm spatial resolution confirm the predicted field distribution profiles.
Article
Engineering, Electrical & Electronic
P. Girault, L. Oyhenart, T. Rouanet, S. Joly, G. Beaudin, M. Canva, L. Bechou, P. G. Charette
Summary: This work presents a detailed modeling-based analysis of integrated micro-ring resonators used for absorption spectroscopy. Typically, sensors based on micro-ring resonators detect changes in the real part of the refractive index of the sensing medium at critical coupling. However, in absorption spectroscopy, micro-ring resonators are used to measure changes in the imaginary part of the index and are most sensitive away from critical coupling, with separate maxima in the under- and over-coupled regimes. The analysis in this work focuses on the under-coupled regime, exploring the relationships between sensitivity, mode confinement, and losses.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Jean-Francois Bryche, Marlo Vega, Julien Moreau, Paul-Ludovic Karsenti, Paul Bresson, Mondher Besbes, Philippe Gogol, Denis Morris, Paul G. Charette, Michael Canva
Summary: Thermoplasmonics has gained increasing attention for generating nanoscale heat sources using photothermal effects in plasmonic nanoparticles. By exciting gold nanoparticles with ultrashort light pulses, high-speed light management and nanoscale heat-sensitive chemical reaction control can be achieved. This study investigates the non-uniform thermal energy distribution in cross-shaped nanostructures using femtosecond transient spectroscopy and a thermooptical numerical model. The results show that the polarization of the excitation light can control heat distribution in the nanostructures, and nonthermal electron ballistic displacement is crucial in fast transient heat dynamics models.
Article
Chemistry, Analytical
M. Vega, J. -F. Bryche, P. -L. Karsenti, P. Gogol, M. Canva, P. G. Charette
Summary: This paper proposes a 2D method for removing coherent artifacts from femtosecond time-resolved spectroscopy data, which is simple, intuitive, and light on computation resources. The effectiveness of the method is demonstrated with experimental data, and it is expected to be applicable to other types of time and wavelength-resolved spectroscopy data.
ANALYTICA CHIMICA ACTA
(2023)
Article
Materials Science, Multidisciplinary
P. Bresson, J-F Bryche, M. Besbes, J. Moreau, P-L Karsenti, P. G. Charette, D. Morris, M. Canva
Proceedings Paper
Engineering, Biomedical
Marion Costella, Marie Frenea-Robin, Julien Marchalot, Julien Moreau, Oleh Andreiev, Michael Canva, Paul Charette
PLASMONICS IN BIOLOGY AND MEDICINE XVII
(2020)
Proceedings Paper
Engineering, Biomedical
Marine Boulade, Thierry Livache, Paul G. Charette, Michael Canva, Loic Leroy
PLASMONICS IN BIOLOGY AND MEDICINE XVI
(2019)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)