Article
Chemistry, Analytical
Danting He, Jia Yang, Jiahui Zhang, Chengguo Hu
Summary: A simple filtration method is reported for the fabrication of salt-induced nanoporous gold electrodes (SINPGEs) from gold nanoparticles (AuNPs). This method utilizes sodium chloride (NaCl) to trigger the aggregation, sintering, and deposition of AuNPs on polyvinylidene fluoride (PVDF) membranes, resulting in the scalable fabrication of flexible SINPGEs with high conductivity, good mechanical property, large surface area, and low cost. The nanoporous structure of SINPGEs improves the electrochemical responses of various species, and the passivation effect of chloride ions on the oxidation of hydrogen peroxide can be repressed by electrochemical activation.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Georgeena Mathew, Miriam Daniel, Karthik Peramaiah, Munuswamy-Ramanujam Ganesh, Bernaurdshaw Neppolian
Summary: Metal-organic frameworks (MOFs) are widely used as supporting materials for electrochemical sensing applications. In this study, Ag nanoparticles were incorporated into a Bi-BDC MOF and used for the detection of hydrogen peroxide (H2O2). The Ag-Bi-BDC MOF showed excellent electrocatalytic activity towards H2O2 detection, thanks to the strong binding interaction of Bi3+ with H2O2, the high porosity of the MOF, and the catalytic activity of Ag particles. The fabricated sensor exhibited a wide linear range, high sensitivity, short response time, and low detection limit for H2O2, as well as good selectivity, stability, and reproducibility. The sensor also showed promising real-time application in detecting H2O2 secreted from cancer cells.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Electrochemistry
Conghui Hou, Qiufen Luo, Yaping He, Hongfang Zhang
Summary: This study investigates the effect of deposition parameters on the electrocatalytic activity of gold nanoparticles (AuNPs) and their performance in various oxidation or reduction reactions. The nucleation and growth processes of AuNPs were found to be controlled by deposition potential and deposition time, respectively, providing insights for further applications of AuNPs.
JOURNAL OF APPLIED ELECTROCHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Linyi Xu, Jing Li, Weishan Shi, Ning Bao, Chunmei Yu
Summary: The synthesis of MnCO3-Au hybrid microspheres and their application in electrochemical biosensing of hydrogen peroxide based on hemoglobin immobilization are reported. The microspheres exhibit unique properties that benefit direct electron transfer of Hb, with high performance and stability for H2O2 detection. The biosensor shows excellent selectivity, repeatability, and long-term stability, with potential for real sample analysis of H2O2.
Article
Chemistry, Analytical
Yuxi Tong, Lifen Wang, Jiajia Song, Mengyue Zhang, Hetong Qi, Shujiang Ding, Honglan Qi
Summary: The study introduces a self-terminated electroless deposition method to prepare surfactant-free and monodispersed Pt nano-particle-modified carbon fiber microelectrodes for the detection of hydrogen peroxide released from living cells. This method ensures high reproducibility and minimizes person-to-person and electrode-to-electrode variations. Additionally, the Pt nano-particles/CFEs exhibit good sensitivity and electrocatalytic activity towards H2O2 oxidation, making them suitable for cellular H2O2 monitoring.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Xiaoxiao Li, Xiaoyan Duan, Peng Yang, Lu Li, Bo Tang
Summary: In this study, robust surface-enhanced Raman spectroscopy (SERS) nanoprobes based on Au nanoparticles were developed for monitoring mitochondrial H2O2 in living cells, showing superior performance compared to traditional nanoprobes.
ANALYTICAL CHEMISTRY
(2021)
Article
Engineering, Environmental
Baiyang Chen, Yuanxi Huang, Qi Zhang, Dionysios D. Dionysiou, Lei Wang, Juan Li
Summary: The study found that VUV irradiation of water leads to the concurrent formation of nitrite and hydrogen peroxide, with increasing pH and decreasing oxygen promoting the conversion of nitrate into nitrite but suppressing hydrogen peroxide formation. These findings highlight the importance of considering both the benefits and drawbacks of VUV processes.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Applied
Qing Zhang, Yuanyuan Zhang, Haibo Chen, Lei Zhang, Peng Li, Huining Xiao, Weibing Wu
Summary: This article describes the controllable and uniform loading of gold nanospheres on cellulose nanocrystals by electrostatic adsorption self-assembly. The particle spacing of gold nanospheres on cellulose nanocrystal surface was successfully regulated by adjusting size, Zeta potential, and loading ratio. This method provides an easy and efficient approach to constructing one-dimensional hot spots, which is crucial for enhancing the performance of surface enhanced Raman scattering spectroscopy. The resulting nanohybrid shows improved reproducibility and sensitivity for SERS detection, making it potentially valuable for sensing applications.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Multidisciplinary
Peng Hu, Shuang Zhao, Jiahua Shi, Fan Li, Shaochen Wang, Ying Gan, Lei Liu, Shuling Yu
Summary: A dual-responsive HMPDA@Cu2-xSe cascade catalytic nanoplatform was constructed for efficient photothermal therapy and controlled drug release. The nanoplatform showed significant tumor cell inhibition effect in vitro and in vivo, demonstrating its potential for effective multi-modal combination therapy for tumors.
Article
Chemistry, Multidisciplinary
Fanghui Chen, Peijing An, Ling Liu, Zhiguo Gao, Yaojia Li, Yuchen Zhang, Baiwang Sun, Jiancheng Zhou
Summary: An intelligent cascade nanoreactor was developed for safe and efficient cancer therapy by combining pH-responsive and photothermal-enhanced nanocatalytic therapy in tumor microenvironment.
Article
Chemistry, Analytical
Ahlem Teniou, Ibrahim A. Madi, Riane Mouhoub, Jean Louis Marty, Amina Rhouati
Summary: In this study, a homogeneous technique was developed for sensitive and rapid quantification of hydrogen peroxide using hemoglobin as a bioreceptor. The chemiluminescence reagent luminol served as a peroxidase substrate and generated a chemiluminescent signal when oxidized by hemoglobin. The biosensor demonstrated high selectivity and a detection limit of 0.308 mM, making it a cost-effective and simple method for monitoring peroxidase substrates.
Article
Electrochemistry
Fan Shi, Hui Cheng, Yucen Yao, Zejun Zhang, Lina Zeng, Lin Li, Wei Sun
Summary: Researchers successfully fabricated a Pt-doped Pd-FeP-C hollow nanorod and constructed a modified electrode, enabling sensitive detections of nitrite, hydrogen peroxide, bromate, and trichloroacetic acid in different ranges.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2022)
Article
Chemistry, Analytical
Cong Zheng, Da Wu, Tao Wang, Jianhong Xiao, Li Yu
Summary: This study developed a novel colorimetric method for detecting hydrogen peroxide (H2O2) and glucose in sodium chloride solutions, based on gold nanoparticles, single-stranded DNA, and ceria nanoparticles. The method can detect the target substances by observing the color change of the aqueous solution, providing a potential avenue for quantitative detection in clinical diagnostics.
Article
Chemistry, Analytical
Darya Vokhmyanina, Elena Daboss, Olesya Sharapova, Mariia Mogilnikova, Arkady Karyakin
Summary: Hydrogen peroxide sensors were made through a single printing step with carbon ink containing catalytically synthesized Prussian blue nanoparticles. The resulting bulk-modified sensors had a wider linear calibration range and a lower detection limit compared to surface-modified sensors, due to decreased noise and increased signal-to-noise ratio. The glucose and lactate biosensors based on these sensors showed similar or higher sensitivities compared to surface-modified biosensors.
Article
Engineering, Environmental
Van-Dat Doan, Quoc-Huy Pham, Bao-An Huynh, Thi-Lan-Huong Nguyen, Anh-Tien Nguyen, Thanh-Danh Nguyen
Summary: In this study, gold nanoparticles (AuNPs) synthesized using an aqueous extract of Cynomorium songaricum (CS) were used as catalysts for the reduction of nitrophenols at various reaction temperatures. The biosynthesized CS-AuNPs showed good stability and low activation energy, and were capable of detecting hydrogen peroxide with a low detection limit of 2.25 µM. It was found that the reduction of nitrophenols followed a Langmuir-Hinshelwood mechanism with a half-order kinetic model, with activation energies as low as 4.88 kJ mol(-1) and 8.66 kJ mol(-1) for different nitrophenols.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)