Article
Materials Science, Multidisciplinary
Ruizhao Tian, Lianyue Li, Kanyu Yang, Zhengchun Yang, Hanjie Wang, Peng Pan, Jie He, Jinshi Zhao, Baozeng Zhou
Summary: An Ag/ZnO/Graphene RRAM structure was prepared through RF magnetron sputtering, showing improved endurance and resistance ratio compared to devices with Au electrode and without electroforming. The density of states of ZnO supercells and their contributions to RRAM performance were calculated and analyzed. The conduction path was confirmed through I-V curve, indicating space-charge-limited conduction of electrons captured by oxygen vacancy traps. Cell toxicity test demonstrated high biocompatibility and broad applicability of Ag/ZnO/Graphene RRAM in implantable biomedical devices.
Article
Physics, Applied
Hongrong Hu, Alexander Scholz, Surya Abhishek Singaraju, Yushu Tang, Gabriel Cadilha Marques, Jasmin Aghassi-Hagmann
Summary: This study presents an inkjet-printed resistive switching device based on an Ag/ZnO/Au structure, exhibiting excellent performance and a stable conduction mechanism.
APPLIED PHYSICS LETTERS
(2021)
Article
Materials Science, Multidisciplinary
Min Yang, Yan Gong, Genli Shen, Zhen Wang, Mi Liu, Qi Wang
Summary: By synthesizing and comparing the gas sensing properties of Au@ZnO, Au-Pd@ZnO, and Au-Pt@ZnO nanoparticles, it was found that the Pt/Pd decorated Au-ZnO hetero-interface has a positive influence on benzene sensing performance.
Article
Multidisciplinary Sciences
Jongmin Park, Hojeong Ryu, Sungjun Kim
Summary: This study investigated the effects of nonideal resistive switching in resistive random-access memory (RRAM) for synaptic devices in neuromorphic systems, such as unstable high-resistance state, negative set, and conductance saturation feature. The study also explored the changes in high-resistance state and the impact of negative set, as well as the saturation characteristics in conductance modulation of the Ag/ZnO/TiN device.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Physical
S. Agnolin, F. Apostolo, L. Di Felice, J. Melendez Rey, A. Pacheko Tanaka, M. Llosa Tanco, F. Gallucci
Summary: To reduce costs, rough and large media grade Hastelloy X filters have been acquired and pre-treated via polishing and chemical etching to serve as metallic supports with sufficient surface quality for highly selective thin Pd-Ag membranes.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Chemistry, Analytical
Sonalika Agarwal, Sanjay Kumar, Himanshu Agrawal, Mohamad G. Moinuddin, Manoj Kumar, Satinder K. Sharma, Kamlendra Awasthi
Summary: The design of hierarchical zinc oxide (ZnO) microstructures modified with silver (Ag) nanoparticles has been proven effective in enhancing hydrogen gas sensing performance. The Ag/ZnO hollow microstructures showed superior sensitivity, fast response and recovery time, as well as good stability, even at low hydrogen gas concentrations. This enhancement in sensing performance is attributed to the chemical and electronic sensitization effect of Ag nanoparticles, leading to a more sensitive sensor with improved selectivity.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Physics, Applied
Krishna Rudrapal, A. Mukherjee, V. Adyam, Ayan Roy Chaudhuri
Summary: The impact of device operation condition and ambient moisture on the resistive switching characteristics of a non-stoichiometric polycrystalline tungsten oxide device was investigated. It was found that current conduction is mainly dominated by Schottky emission at low electric field and Poole-Frenkel emission at high electric field.
JOURNAL OF APPLIED PHYSICS
(2021)
Article
Nanoscience & Nanotechnology
Jinhao Zhang, Xin Wang, Zhiwei Yang, Jian Wang, Jiacheng Cao, Qian Chen, Shilong Yu, Jian Zhang, Tianwen Guo, Hai Li, Xiao Huang
Summary: In this study, egg-shell EGaIn/Ag/ZnO ternary composite particles were prepared as a wearable sensor capable of both pressure and proximity detection. The sensor showed excellent sensitivity to low pressures and could detect approaching objects up to 20 cm away. By combining the sensing curves in touchless and touching modes, the extracted parameters could be used to create fingerprints for different objects, demonstrating the potential of the sensor in the differentiation and identification of unknown objects for future robotics and artificial intelligence.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Nguyen Minh Vuong, Do Dai Duy, Hoang Nhat Hieu, Van Nghia Nguyen, Nguyen Ngoc Khoa Truong, Hao Van Bui, Nguyen Van Hieu
Summary: Highly responsive methanol sensors operating at low temperatures were developed by decorating hierarchical ZnO nanorods with Pt nanoparticles. The surface modification significantly enhanced the sensing response to methanol and enabled lower working temperatures.
Article
Materials Science, Multidisciplinary
Jing-Shiuan Niu, Chia-Hong Huang, Wei-Che Shao, Jung-Hui Tsai, Wen-Chau Liu
Summary: In this study, an Al2O3 thin film was deposited on interdigitated electrodes to fabricate a resistive hydrogen sensor. By using Pd nanoparticles/Pd film as catalytic metals, the gas sensing performance was enhanced due to the increased surface area and spill-over effect. The sensor showed a sensing response ratio of 14.4% in 1000 ppm H-2/air at 300 degrees C, making it suitable for high-temperature hydrogen detection.
ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Radhyah Mahdi Al Jarrah, Eman Muslem Kadhem, Adel H. Omran Alkhayatt
Summary: In this study, nanostructure ZnO thin films were fabricated using the chemical spray pyrolysis method with annealing at different temperatures. The research found that annealed ZnO thin films exhibited improved crystal structure and surface topography, which resulted in increased sensitivity of the gas sensors. The optimal operating temperature for the sensors was determined to be 200 degrees Celsius.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2022)
Article
Chemistry, Analytical
A. S. Chizhov, M. N. Rumyantseva, K. A. Drozdov, I. Krylov, M. Batuk, J. Hadermann, D. G. Filatova, N. O. Khmelevsky, V. F. Kozlovsky, L. N. Maltseva, A. M. Gaskov
Summary: This study synthesized a ZnO/CsPbBr3 nanocomposite, showing enhanced photoresponse to different gases under light illumination and sensor response, with better performance compared to pure ZnO, and a distinct sensor response to NO2 within a temperature range.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Pawan Pathak, Hyoung Jin Cho
Summary: A flexible hydrogen sensor with enhanced response and high selectivity at room temperature has been successfully fabricated using self-assembled thiol films and DC sputtering technique. The sensor shows promise for applications in hydrogen-powered vehicles and other clean energy devices.
Article
Chemistry, Inorganic & Nuclear
Umar Arif, Farman Ali, Ali Bahader, Sharafat Ali, Amir Zada, Fazal Raziq
Summary: This study developed a three-component photocatalyst hetero-junction of Ag-ZnO/g-C3N4 for efficient CO2 reduction. The optimized nano-composite exhibited exceptional visible-light photoactivity, increasing the conversion efficiency of CO2 to CO and methane production.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Materials Science, Multidisciplinary
G. X. Wan, Y. Feng, F. F. Zhang, X. W. Sun, Y. X. Li, R. J. Xue
Summary: ZnO/CeO2 and Ag/ZnO/CeO2 nanocomposites were successfully synthesized via hydrothermal method and characterized. Ag/ZnO/CeO2 nanoparticles with a size of 54 nm were obtained. Gas sensors based on the nanocomposites were fabricated and their ethanol sensing properties were investigated.
Article
Chemistry, Analytical
Akshaya Mouly Vijayakumari, Azad Ravi Oraon, Sonalie Ahirwar, Amala Kannath, K. J. Suja, Palash Kumar Basu
Summary: This study focuses on the development and optimization of a CO2 sensor based on a CuxO/NiO nanostructured matrix, which shows high selectivity to CO2 at 250 degrees Celsius. By explaining the mechanism of CO2 adsorption and desorption, a working sensor prototype is developed. By analyzing the sensor's dynamic characteristics and other factors, an attempt is made to analyze the performance of the developed sensor.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Multidisciplinary Sciences
Md Rabiul Islam, Soujit Sen Gupta, Sourav Kanti Jana, Thalappil Pradeep
Summary: Capacitive deionization (CDI) is an efficient desalination technology that can remove ionic contaminants and toxic species, including heavy metal ions.
Article
Chemistry, Multidisciplinary
Krishna Thej Pammi Guru, Jamuna Surendran Sreeja, Dhrishya Dharmapal, Suparna Sengupta, Palash Kumar Basu
Summary: Exosomes, secreted by most cells, are present in biological fluids such as blood, tears, sweat, and urine, containing lipids, DNA, proteins, and RNA. There is a need for rapid and efficient methods to isolate small exosomes, with current techniques being time-consuming and instrument-dependent. A new technique using citrate-capped gold nanoparticles has shown promise in selectively isolating small exosomes from serum in less than two hours.
Article
Engineering, Electrical & Electronic
M. Akshaya, K. J. Suja, Palash Kumar Basu
Summary: This research focuses on detecting cholesterol abnormalities using an optimized detection layer with TiO2/WO3 nanocomposites and deep-UV LED activation. The sensor shows improved sensitivity and selectivity, allowing for early diagnosis of diseases in a non-invasive manner.
IEEE SENSORS JOURNAL
(2022)
Article
Nanoscience & Nanotechnology
Sourav Kanti Jana, Kamalesh Chaudhari, Md Rabiul Islam, Ganapati Natarajan, Tripti Ahuja, Anirban Som, Ganesan Paramasivam, Addanki Raghavendra, Chennu Sudhakar, Thalappil Pradeep
Summary: This study presents a biomimetic electrode using electrochemically reduced graphene oxide (ERGO) for selective and sensitive detection of arsenic in field water samples. Raman and FTIR spectroscopies were used to understand the mechanism of selectivity and sensitivity. The ion selectivity depends on both structural and electronic factors.
ACS APPLIED NANO MATERIALS
(2022)
Article
Engineering, Electrical & Electronic
R. G. Anjitha, Palash Kumar Basu
Summary: The selectivity of CO and CH4 in metal-oxide-based sensors remains a challenge for researchers due to the analogous sensing mechanism for both gases. In this study, a selective photocatalyst layer (Zn-5(OH)(8)Cl-2.H2O) was introduced on Pd-ZnO to achieve selective sensing of CH4 (up to 1 ppm) and CO (up to 1 ppm). The incorporation of a photocatalytic layer greatly improved the sensor's absorption reaction and surface conversion kinetics. The work also explores the role of dual activation and photocatalytic activity in selectivity and tunability. The achieved sensitivity and stability of the sensor make it a promising approach for gas sensing applications. Rating: 8/10.
IEEE SENSORS JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Nisha, Palash Kumar Basu
Summary: This work provides a detailed study on the gasochromic properties of tungsten oxide at different operating conditions, sol and doping concentrations. The hydrogen sensing results are compared with material characterization to gain more insight into the gasochromic performance. The effect of noble metal doping on the gasochromic behavior is also explored, and Pt-doped samples show better response than Pd-doped ones.
IEEE SENSORS JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Ankit Nagar, Md Rabiul Islam, Kartheek Joshua, Tanvi Gupte, Sourav Kanti Jana, Sujan Manna, Tiju Thomas, Thalappil Pradeep
Summary: Researchers have developed a macroscopic reverse electrodialysis (RED) system that utilizes selective ion transport across charged nanochannels to harness the Gibbs free energy difference between seawater and river water. The system employs cation-selective and anion-selective membranes composed of reduced graphene oxide (rGO) nanosheets decorated with TiO2 nanoparticles. The membranes exhibit excellent ion transport properties and high power densities under artificial salinity gradients.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Krishna Thej Pammi Guru, Nusrat Praween, Palash Kumar Basu
Summary: In this study, a gold-nanoparticle-coated silicon wafer functionalized with polyethylene glycol was used to immobilize exosomes for quantification. The technique showed an increase in size range and total number of isolated exosomes with higher density of gold nanoparticles. The proposed method offers advantages such as reusability, minimal instrumental requirement, fast isolation, and compatibility with microfluidic platforms.
Article
Chemistry, Multidisciplinary
Pillalamarri Srikrishnarka, Raaga Madhuri Dasi, Sourav Kanti Jana, Tripti Ahuja, Jenifer Shantha Kumar, Ankit Nagar, Amoghavarsha Ramachandra Kini, Boby George, Thalappil Pradeep
Summary: A frugal humidity sensor has been developed to detect changes in the humidity of exhaled breath. The sensor is made using a cloth as a substrate, with a humidity-sensitive conducting polymer formed on it. Screen-printed silver electrodes and conducting threads connect the sensor to the measurement circuit. The sensor's response time allows for differentiation between fast, normal, and slow breathing. An Android-based mobile application and time series classification algorithm have been used for data collection and analysis. The sensor has also been integrated into a face mask to create a smart mask for monitoring breathing patterns.
Article
Engineering, Electrical & Electronic
Nisha, Palash Kumar Basu
Summary: A novel method of sodium-ion detection from aqueous solutions based on a change of optical transmittance is proposed. Tungsten oxide-coated indium tin oxide (ITO) samples for selective sodium-ion detection are prepared from varying concentrations of peroxo tungstic oxide precursors using a simple cathodic electrodeposition method. The sensor exhibits good selectivity toward N+ compared to K+ and Ca2+ ions and linear response in the range of 10-150 mM Na+. Simple construction, higher response, and selectivity make it a promising method for sodium sensing in food industries and health monitoring.
IEEE SENSORS JOURNAL
(2023)
Article
Chemistry, Analytical
Krishna Thej Pammi Guru, Nusrat Praween, Palash Kumar Basu
Summary: In this study, exosomes were isolated and detected from human serum using a Screen-Printed Electrode, electric field lysis and electrochemical impedance spectroscopy (EIS). The effects of different electrical signals on exosome lysis were investigated, and HER2, a breast cancer biomarker, was successfully detected. The technique not only releases cargo proteins from exosomes, but also improves the detection of surface proteins associated with exosomes.
Article
Materials Science, Multidisciplinary
Anagha Jose, Arijit Jana, Tanvi Gupte, Akhil S. Nair, Keerthana Unni, Ankit Nagar, Amoghavarsha R. Kini, B. K. Spoorthi, Sourav Kanti Jana, Biswarup Pathak, Thalappil Pradeep
Summary: We successfully synthesized vertically aligned nanoplates of the [Co6S8DPPE6Cl6] cluster (Co6) using ambient electrospray deposition (ESD). These nanoplates demonstrate sensitive and selective electrochemical response toward arsenite at concentrations as low as 5 parts per billion. Our work sheds light on the preferential binding of arsenite with Co6, revealing a practical application of atomically precise clusters with societal relevance.
ACS MATERIALS LETTERS
(2023)
Proceedings Paper
Engineering, Electrical & Electronic
R. G. Anjitha, Palash Kumar Basu
Summary: The main criteria for fabricating a practical sensor are cross-sensitivity and reliability. The exploration of nanomaterials and proper activation techniques is essential to address this issue. Pd-doped ZnO has been selected as the nanomaterial and dual activation technique is used to optimize the sensor for selective gas detection. By considering the dissociation energy of the target gases, the dynamic characteristics are analyzed using the principle of dual activation. As a result, a reliable, robust, and cost-effective sensor is fabricated.
Article
Engineering, Electrical & Electronic
R. G. Anjitha, Sonalie Ahirwar, L. Karthikeyan, J. Subhash, Kamaljeet Singh, Ajay Andhiwal, Palash Kumar Basu
Summary: Continuous monitoring of gases at low concentrations, especially CO, is important for maintaining the safety of coal mines. This study investigates a selective CO sensor that operates at ppm level and triggers an alarm system. By exploring different material combinations (Pd-ZnO) and optothermal activation techniques, the researchers have developed a reliable, robust, and cost-effective CO-selective gas sensor. The use of nanomaterials with defect-oriented active sites has played a significant role in improving the sensor's performance and selectivity. The study also discusses the simulation, optimization, fabrication, and characterization processes involved in producing the CO-selective sensor.
ACS APPLIED ELECTRONIC MATERIALS
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)