Article
Materials Science, Biomaterials
Jian Xiong, Bin Zhang, Andrew Balilonda, Shengyuan Yang, Kerui Li, Qinghong Zhang, Yaogang Li, Hongzhi Wang, Chengyi Hou
Summary: This article introduces a modified graphene-based fiber electrode which not only retains the excellent electrical properties of graphene fiber electrode, but also enhances the charge storage capacity. The modified electrode demonstrates effective control and safety in in vivo experiments.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Chemistry, Analytical
Paula Portugal-Gomez, Olga Dominguez-Renedo, M. Asuncion Alonso-Lomillo
Summary: This study reports the use of different cobalt phthalocyanine/nanomaterials-based sensors for the headspace detection of volatile thiols. The best performance was achieved by using carbon sensors modified with cobalt phthalocyanine. The optimized amperometric procedure showed good reproducibility, capability of detection, and decision limit for ethanethiol quantification in white and red wines.
Article
Chemistry, Multidisciplinary
A. Chathuri De Alwis, J. Dylan Denison, Ruby Shah, Gregory S. McCarty, Leslie A. Sombers
Summary: Carbon fiber microelectrodes are commonly used for real-time monitoring of exocytosis events. This study compared the performance of 10-μm and 34-μm diameter microelectrodes and found that the larger electrode was more sensitive to certain molecules and covered the entire cell, leading to better detection of exocytosis events and quantal size.
Article
Engineering, Environmental
Linbin Hu, Run Liu, Yang Yang, Qian Fu, Liang Zhang, Xun Zhu, Qiang Liao, Jun Li
Summary: Maintaining electroactive biofilms with good metabolic activity is essential for high and stable performance in bioelectrochemical systems (BESs). Proton transport plays a significant role in biofilm metabolic activity through microenvironment pH, making it crucial to investigate proton transfer properties within the biofilms to enhance BES performance. In this study, the proton transport in electroactive biofilms was explored using in situ microelectrode measurements, which innovatively measured the diffusion coefficient in live biofilms under non-destructive conditions. The non-destructive measurement of diffusion coefficients not only brings the results closer to reality, but also enriches the understanding of biochemical processes and physicochemical information. By combining with a mathematical model, it was demonstrated that the accumulation of protons in the biofilm is a key factor in inhibiting electricity generation. The efficient characterization of proton transfer within the biofilm provides realistic guidance for constructing high-performance BESs.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Materials Science, Multidisciplinary
Taiwo Musa Adeniji, Keith J. J. Stine
Summary: We discuss the development of nanostructure-modified electrode surfaces for the electrochemical detection of environmental contaminants. These contaminants, found in everyday substances such as pharmaceuticals, pesticides, and personal care products, pose a threat to human and environmental wellbeing. Researchers have used various electrochemical techniques to detect these pollutants in different environmental matrices, often finding that nanomaterial-modified electrodes offer superior sensitivity and performance compared to standard electrodes. We review the properties of these nanomaterials and suggest further directions for improving the sensitivity and selectivity of these modified electrodes.
Article
Electrochemistry
Jin Song, Yiwei Li, Dingkun Ke, Dianbing Wang, Xian-En Zhang
Summary: By integrating graphene with carbon microelectrode arrays, a sensitive biosensor platform has been developed for studying biofilm formation and screening antibiofilm drugs. The graphene-modified microelectrode arrays demonstrated better performance and higher specificity in detecting biofilm growth.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Physical
Md Sazzad Hossain, Lisa Stephens, Janine Mauzeroll, Steen B. Schougaard
Summary: Scanning electrochemical microscopy (SECM) is a useful technique for characterizing the diffusion coefficients in porous media, with a transitional frontier from hemispherical to cylindrical diffusion. Experimental parameters were examined through simulations to derive a best practice thickness criterium and found an empirical formulation in the response below a certain thickness limit. This analysis solidifies SECM as a reliable tool for characterizing mass transport in porous films over a wide range of thicknesses.
JOURNAL OF POWER SOURCES
(2021)
Article
Nanoscience & Nanotechnology
Xiangchen Li, Subash C. B. Gopinath, Xin Peng, Jiudi Lv
Summary: An aptasensor was developed on an interdigitated microelectrode (IDME) for the diagnosis of ulcerative colitis by detecting the biomarker lipocalin-2. The sensor achieved higher immobilization of the anti-lipocalin-2 aptamer probe by utilizing zeolite particles aided by sodium dodecyl benzenesulfonate. This method demonstrated efficient and specific detection of lipocalin-2 with clinical diagnostic potential.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2021)
Article
Chemistry, Analytical
Ema Gricar, Kurt Kalcher, Bostjan Genorio, Mitja Kolar
Summary: Four different graphene-based nanomaterials were synthesized, characterized, and utilized as modifiers of carbon paste electrodes to develop a non-enzymatic amperometric hydrogen peroxide sensor for complex matrices. The optimized sensor exhibited a wide linear range, excellent detection limit, and high stability, making it suitable for real sample analysis in pharmaceutical and saliva matrices. The recovery values for commercial pharmaceutical products and saliva samples demonstrated the accuracy and reliability of the sensor in practical applications.
Article
Chemistry, Analytical
A. Kumaravel
Summary: Stable silver nanoparticles with a diameter less than 20 nm were prepared using SDS as a reducing and stabilizing agent. The developed modified electrodes exhibited high catalytic activity towards the reduction of clothianidin. The electrochemical results were validated by comparing them to HPLC results.
ANALYTICAL METHODS
(2022)
Article
Electrochemistry
Junqiao Lee, Jesse W. Mullen, Ghulam Hussain, Debbie S. Silvester
Summary: Microelectrodes are popular in electroanalysis for high current density, which can be further increased by multiplying the number of electrodes in an array configuration. The spacing between microelectrodes significantly affects the deposition effects and current responses, with smaller spacing potentially allowing for higher electrode density.
ELECTROCHIMICA ACTA
(2021)
Article
Engineering, Biomedical
Prem C. Pandey, Govind Pandey, Roger J. Narayan
Summary: In this study, a microneedle-based electrochemical biosensor was fabricated using a Prussian blue-gold nanohybrid as the working electrode. The nanohybrid was synthesized simultaneously from Prussian blue and gold nanoparticles with the assistance of polyethylenime, showing excellent catalytic activity and suitable analytical performance for biomedical applications.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Laszlo Kiss, Sandor Kunsagi-Mate
Summary: The effects of scan rate and the concentration of substituted phenols on peak currents or current plateaus were investigated. The voltammetric curves recorded by a platinum microelectrode showed significant variation under different experimental conditions for different phenols. The diffusion-controlled process of 4-methoxyphenol was determined based on the solvents used and the diffusion coefficients showed an inverse relationship with solvent viscosities.
CANADIAN JOURNAL OF CHEMISTRY
(2023)
Article
Engineering, Environmental
Shuang-Yu Pi, Ming-Ying Sun, Yue-Fei Zhao, Yun-Xiao Chong, Da Chen, Hai Liu
Summary: In this study, a flow-through electrode system (FES) was constructed using Co3O4 nanowire electrodes, which achieved rapid and efficient water disinfection. The disinfection mechanisms were found to be electroporation and electrochemical oxidation on the Co3O4 nanowire anode. The FES showed good removal efficiency for various bacterial species.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Laszlo Kiss, Sandor Kunsagi-Mate
Summary: This study investigates the effects of scan rate and the concentration of substituted phenols on peak currents or current plateaus. The voltammetric curves recorded by a platinum microelectrode show significant variations under different experimental conditions for 4-chlorophenol, 4-tert-butylphenol, and 4-nitrophenol. Linear dependence between plateau current / peak current and phenol concentration is observed for 4-methoxyphenol and 4-tert-butylphenol in the lower concentration range in acetonitrile. Diffusion-controlled processes are found in the electrode reaction of 4-methoxyphenol in various solvents. The diffusion coefficients show an inverse proportional relationship with solvent viscosities, in agreement with known theories.
CANADIAN JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Josune J. Ezenarro, Tobias Nils Ackerman, Pablo Pelissier, Doriane Combot, Laurent Labbe, Xavier Munoz-Berbel, Jordi Mas, Francisco Javier del Campo, Naroa Uria
Summary: Cyanobacterial blooms can produce toxins, deplete oxygen, and affect water quality, but current technologies for detecting cyanobacteria are limited by cost and complexity. A new portable photonic system has been developed that can detect low concentrations of cyanobacteria in water samples quickly and effectively, making it a potentially powerful tool for early warning and detection of pathogens in water.
ANALYTICAL CHEMISTRY
(2021)
Article
Acoustics
Amparo Ferrer-Vilanova, Yasmine Alonso, Jiri Dietvorst, Marta Perez-Montero, Rosalia Rodriguez-Rodriguez, Kristina Ivanova, Tzanko Tzanov, Nuria Vigues, Jordi Mas, Gonzalo Guirado, Xavier Munoz-Berbel
Summary: This technology utilizes sonochemical coating to create robust blue-colored textiles with bacterial sensing capability, enabling on-site detection of live bacteria. The textiles are sensitive to both Gram-positive and Gram-negative bacteria, recover their original blue color through oxidation-reduction reactions, and can be applied to various materials for controlling and preventing microbial infections in hospitals, industries, schools, and homes.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Biophysics
Sara Santiago-Malagon, Diego Rio-Colin, Haniyeh Azizkhani, Miguel Aller-Pellitero, Gonzalo Guirado, F. Javier del Campo
Summary: This study describes the construction of a self-powered electrochromic device for the determination of metabolites in sweat, which can be visualized by the naked eye. By utilizing screen-printing technology, the device is able to simplify the complexity of skin-patch wearable sensors, potentially leading to a powerful analytical tool without the need for external detection systems.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Physical
C. M. Costa, J. C. Barbosa, R. Goncalves, H. Castro, F. J. Del Campo, S. Lanceros-Mendez
Summary: This work provides an overview on the relevance of recycling Lithium-ion batteries (LIBs) and their environmental impact. It analyzes the components and market value of LIBs, addresses different recycling methods for critical metals like cobalt and nickel, and describes the main environmental issues associated with the production, use and end of life of LIBs for electric vehicles.
ENERGY STORAGE MATERIALS
(2021)
Review
Chemistry, Analytical
Josune J. Ezenarro, Jordi Mas, Xavier Munoz-Berbel, Naroa Uria
Summary: This review summarizes the recent advances in bacterial concentration/detection platforms, with a focus on the concentration strategy. By introducing and comparing five concentration strategies, namely centrifugation, filtration, magnetic separation, electric separation, and acoustophoresis, the review aims to facilitate the development of future platforms for fast, sensitive, and in situ bacterial detection in real samples.
ANALYTICA CHIMICA ACTA
(2022)
Review
Medicine, General & Internal
Karla Jaimes Merazzo, Joseba Totoricaguena-Gorrino, Eduardo Fernandez-Martin, F. Javier del Campo, Eva Baldrich
Summary: Smartphones are becoming more versatile thanks to the sensors and actuators packed in them, enabling new applications beyond their original purpose. Personalized diagnostics is an area where mobile devices can have a significant impact, with potential for more advanced applications in the future. However, current technologies have not fully exploited the capabilities of mobile devices for personalized diagnostics.
Article
Biochemical Research Methods
Anahita Hosseini, Jordi Mas
Summary: This study establishes the optimal conditions for beta-galactosidase assay and highlights the importance of sample induction, permeabilization, and enzyme substrate selection in determining the sensitivity of the detection. It is crucial to ensure that the substrate concentration is high enough (around 3 to 4 times K-m) to prevent limited activity and that the pH at the time of reading is sufficiently high for maximum signal.
ANALYTICAL BIOCHEMISTRY
(2021)
Article
Chemistry, Analytical
Jiri Dietvorst, Amparo Ferrer-Vilanova, Sharath Narayana Iyengar, Aman Russom, Nuria Vigues, Jordi Mas, Lluisa Vilaplana, Maria-Pilar Marco, Gonzalo Guirado, Xavier Munoz-Berbel
Summary: This study introduces a cyanotype-based photochemical amplification reaction for detecting low bacterial concentrations efficiently and simply, which is expected to have a significant impact on clinical diagnosis of infectious diseases.
ANALYTICAL CHEMISTRY
(2022)
Article
Electrochemistry
Alejandro Fidel Alba, Joseba Totoricaguena-Gorrino, Maria Belen Sanchez-Ilarduya, Leire Ruiz-Rubio, Jose Luis Vilas-Vilela, Senentxu Lanceros-Mendez, Francisco Javier del Campo
Summary: This study demonstrated that treating commercial screen-printed carbon electrodes with a CO2 laser can enhance their performance, increase crystallinity, improve electron transfer rates, and facilitate the simultaneous detection of multiple substances such as dopamine. The laser treatment also helped introduce oxygen groups, increasing sensitivity of the sensor for target substances.
ELECTROCHIMICA ACTA
(2021)
Article
Microbiology
Teresa Lucena, Olga Sanchez, Isabel Sanz-Saez, Silvia G. Acinas, Laura Garrido, Jordi Mas, M. Carmen Macian, Maria A. Ruvira, David R. Arahal, Maria J. Pujalte
Summary: Two strains of bacteria isolated from activated sludge in a seawater-based wastewater treatment plant in Spain were found to be potentially new taxa. One strain was distantly related to Vicingus serpentipes and other members of the order Flavobacteriales, while the other strain was a putative new species of Lysobacter. Based on a comprehensive taxonomic analysis, new taxa were proposed.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2022)
Article
Chemistry, Analytical
E. Forner, J. J. Ezenarro, M. Perez-Montero, N. Vigues, A. Asensio-Grau, A. Andres, J. Mas, M. Baeza, X. Munoz-Berbel, R. Villa, G. Gabriel
Summary: There is a growing demand for alternative methods to animal testing. This article presents a microbial biosensor based on fully biocompatible materials which is able to detect acetate in a specific range. The results show the successful use of bacteria as a biosensing tool, utilizing inkjet printed transducers, biocompatible materials, and cell entrapment technologies.
Article
Materials Science, Multidisciplinary
Alejandro Fidel Alba, Joseba Totoricaguena-Gorrino, Lia Campos-Arias, Nikola Perinka, Leire Ruiz-Rubio, Jose Luis Vilas-Vilela, Senentxu Lanceros-Mendez, Francisco Javier del Campo
Summary: A laser-based process was used to selectively transform the surface of conventional SPCEs into highly homogeneous HOPG, resulting in excellent electrode kinetics and capacitance performance.
MATERIALS ADVANCES
(2021)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
