Microfluidic centrifuge of nano-particles using rotating flow in a microchamber

This paper presents the centrifugation of the nano-particles using the rotating flow in the microchamber. The feasibility of the microfluidic centrifuge was demonstrated numerically and experimentally. The centrifugation of the nano-particles of 300 and 500 nm was visualized by using a high-speed CCD camera and a micro-PIV. In addition, its performance was characterized quantitatively. The experimental results of the mechanical contact-free microfluidic centrifuge showed the same physical phenomena with the conventional one even in its small size. Also, a new finding was obtained that the transient motion influenced the stable operation of the microfluidic centrifuge. (c) 2007 Elsevier B.V. All rights reserved.