Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice
出版年份 2015 全文链接
标题
Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice
作者
关键词
-
出版物
Scientific Reports
Volume 5, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-09-08
DOI
10.1038/srep13842
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Sex modifies theAPOE-related risk of developing Alzheimer disease
- (2014) Andre Altmann et al. ANNALS OF NEUROLOGY
- Apolipoprotein E in Alzheimer's Disease: An Update
- (2014) Jin-Tai Yu et al. Annual Review of Neuroscience
- The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
- (2014) Kanchan Garai et al. BIOCHEMISTRY
- Amyloid-β Pathology andAPOEGenotype Modulate Retinoid X Receptor Agonist Activityin Vivo
- (2014) Leon M. Tai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alzheimer’s Disease Genetics: From the Bench to the Clinic
- (2014) Celeste M. Karch et al. NEURON
- Reduced phosphorylation of brain insulin receptor substrate and Akt proteins in apolipoprotein-E4 targeted replacement mice
- (2014) Qi-Rui Ong et al. Scientific Reports
- Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice
- (2014) Shan-May Yong et al. Scientific Reports
- Levels of Soluble Apolipoprotein E/Amyloid-β (Aβ) Complex Are Reduced and Oligomeric Aβ Increased withAPOE4and Alzheimer Disease in a Transgenic Mouse Model and Human Samples
- (2013) Leon M. Tai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Apolipoprotein E4 Causes Age- and Sex-Dependent Impairments of Hilar GABAergic Interneurons and Learning and Memory Deficits in Mice
- (2013) Laura Leung et al. PLoS One
- ApoE influences amyloid- (A ) clearance despite minimal apoE/A association in physiological conditions
- (2013) P. B. Verghese et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biochemistry of Amyloid -Protein and Amyloid Deposits in Alzheimer Disease
- (2013) C. L. Masters et al. Cold Spring Harbor Perspectives in Medicine
- Plasma Amyloid-β as a Predictor of Dementia and Cognitive Decline
- (2012) Alain Koyama et al. ARCHIVES OF NEUROLOGY
- Is Insulin Action in the Brain Clinically Relevant?
- (2012) B. M. Filippi et al. DIABETES
- APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease
- (2012) Katherine L. Youmans et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
- (2012) Theresa R. Bomfim et al. JOURNAL OF CLINICAL INVESTIGATION
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Cdk5/p25-Induced Cytosolic PLA2-Mediated Lysophosphatidylcholine Production Regulates Neuroinflammation and Triggers Neurodegeneration
- (2012) J. R. Sundaram et al. JOURNAL OF NEUROSCIENCE
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid- (A ) and acts in concert with A to elicit neuronal and behavioral deficits in mice
- (2011) N. Bien-Ly et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer's Disease
- (2011) D. J. Selkoe Cold Spring Harbor Perspectives in Biology
- Insulin Receptor Dysfunction Impairs Cellular Clearance of Neurotoxic Oligomeric Aβ
- (2009) Wei-Qin Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increased Membrane Cholesterol Might Render Mature Hippocampal Neurons More Susceptible to -Amyloid-Induced Calpain Activation and Tau Toxicity
- (2009) A. M. Nicholson et al. JOURNAL OF NEUROSCIENCE
- Human APOE Isoform-Dependent Effects on Brain -Amyloid Levels in PDAPP Transgenic Mice
- (2009) K. R. Bales et al. JOURNAL OF NEUROSCIENCE
- Amyloid beta oligomers induce impairment of neuronal insulin receptors
- (2007) Wei-Qin Zhao et al. FASEB JOURNAL
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