Article
Marine & Freshwater Biology
Matthew T. Barbour, Justin R. Schueller, Todd J. Severson, Jeremy K. Wise, Matthew J. Meulemans, James A. Luoma, Diane L. Waller
Summary: Researches focused on the synergistic effects of toxicant mixtures in controlling aquatic invasive species have shown that using synergistic combinations can decrease the overall volume and concentration of individual toxicants required for treatments, thereby reducing costs.
AQUATIC TOXICOLOGY
(2021)
Article
Environmental Sciences
Ze-Jun Wang, Shu-Shen Liu, Peng Huang, Ya-Qian Xu
Summary: This study compared the mPNEC values derived by the IA method and the CA method based on SSD models, finding that the mPNEC values obtained by the IA method were generally more conservative, especially for commonly used distribution functions. This provides a new direction for the application of the IA model in risk assessment and enriches the framework of mixture risk assessment.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Green & Sustainable Science & Technology
Anis Askari, Farzaneh Vahabzadeh, Mohammad Mahdi Mardanpour
Summary: A microbial fuel cell (MFC) based biosensor was developed to quantitatively determine LAS concentration in wastewater, achieving a linear correlation between current density and LAS concentration within a certain range. The MFC also demonstrated potential for power generation and purification in addition to its accurate biosensing capabilities.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Environmental Sciences
Li-Tang Qin, Min Liu, Xin Zhang, Ling-Yun Mo, Hong-Hu Zeng, Yan-Peng Liang
Summary: The study investigated the toxicological interactions of HAA mixtures in green algae and predicted DBP mixture toxicities based on different models. Results showed that mixture effects were synergistic in 47.1% and antagonistic in 25%, while additive effects were only observed in 27.9% of experiments. Predictive models failed to accurately predict mixture toxicity.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2021)
Article
Environmental Sciences
Hongyan Shen, Mingru Yang, Jing Wang, Xiaoming Zou, Danqing Tong, Yulian Zhang, Liang Tang, Haoyu Sun, Lei Yang
Summary: The study used concentration addition to evaluate the joint resistance action of antibacterial mixture, finding that the action is dose-dependent and influenced by the agents' modes of action and survival pressure.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Pharmacology & Pharmacy
Krisztina Pesti, Matyas C. Foldi, Katalin Zboray, Adam Toth, Peter Lukacs, Arpad Mike
Summary: An automated patch-clamp protocol was developed for screening sodium channel inhibitor compounds, which exhibit specific inhibition patterns regardless of concentration. The study aims to quantify compound-specific properties and neutralize the concentration effect, revealing insights into the mechanism of action and kinetics of drug compounds.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Chemistry, Analytical
Jürgen Beck, Matthias Biechele, Christoph Repik, Petra Gruber, Paul G. Furtmueller, Rainer Hahn
Summary: This study systematically compared the elution behavior of plasmid DNA on three common anion exchange resins. It was found that plasmid DNA consistently elutes at a characteristic salt concentration in linear gradient elution, and elutes only above this concentration in isocratic elution. Structural analysis supported this explanation.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Infectious Diseases
Rebecca E. Glover, Nichola R. Naylor
Summary: This brief report reviews the costing and budgeting tool provided by the World Health Organization (WHO) for the national action plans (NAPs) on antimicrobial resistance (AMR). It calls for future cost analyses to consider expenses beyond implementation and utilize available open-access data and tools, such as the Global Antimicrobial Resistance and Use Surveillance System (GLASS) and existing One Health tools within the WHO toolbox.
JAC-ANTIMICROBIAL RESISTANCE
(2023)
Review
Chemistry, Analytical
Guozhen He, Tao Dong, Zhaochu Yang, Are Branstad, Lan Huang, Zhuangde Jiang
Summary: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally, and the lack of early diagnosis and treatment leads to increased economic burden and medical costs. Decentralized point-of-care diagnostics, such as paper-based analytical devices, offer a cost-effective solution for COPD diagnosis and management, reducing medical expenditures.
Article
Chemistry, Multidisciplinary
Joao Simoes, Tao Dong, Zhaochu Yang
Summary: This study developed a new flexible organic photodiode with improved sensitivity and performance in the near-infrared range by optimizing the structure and materials of the photodetector. By integrating the photodiode into a photoplethysmography sensor, oxygen saturation and heart rate were successfully measured.
ADVANCED MATERIALS INTERFACES
(2022)
Article
Chemistry, Analytical
Guozhen He, Tao Dong, Zhaochu Yang, Zhuangde Jiang
Summary: This paper presents a novel strategy of automatic timed detection antibody release to mitigate the high-dose hook effect in sandwich lateral flow assay (LFA) without additional manual steps. By introducing an intermediate pad treated with saturated sucrose solution, the flow between the nitrocellulose membrane and the conjugate pad is regulated to delay the reaction between detection antibodies and analytes. The strategy demonstrated a wider detection range without sacrificing the limit of detection compared to conventional LFA.
Article
Engineering, Electrical & Electronic
Weizhuo Gao, Weixuan Jing, Zehao Li, Qiong Wu, Feng Han, Libo Zhao, Zhaochu Yang, Zhuangde Jiang
Summary: Two types of crescentic ZnONR-based micro-fluidic reactors were constructed using ZnO nanorods, showing high efficiency in degrading aqueous methylene blue solution under UV irradiation. The Zn2+ concentration significantly affected the reaction constant and the surface area of contact between the ZnONRs and the solution.
MICROELECTRONIC ENGINEERING
(2022)
Article
Biophysics
Xiao Hu, Chenghui Yu, Tao Dong, Zhaochu Yang, Yiru Fang, Zhuangde Jiang
Summary: Bipolar disorder, a severe mental illness, is commonly misdiagnosed and diagnosed late due to subjective judgment in the diagnostic procedure. In vitro diagnostic techniques for bipolar disorder have been developed to enhance accuracy in diagnosis, as biomarker research continues to progress. This systematic review summarizes recent studies in this field, discussing the development of instant test products that may benefit clinicians and patients. The controversy surrounding biomarkers is explored, suggesting that multilevel testing with multiple biomarkers may improve diagnostic confidence. Furthermore, attention should be given to different reference values for biomarkers based on age, gender, etc. Overall, this review on biomarkers for bipolar disorder may pave the way for the development of point-of-care testing (POCT) and inform future product research and development.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Chemistry, Multidisciplinary
Tao Dong, Nuno Miguel Matos Pires, Zhaochu Yang, Zhuangde Jiang
Summary: The focus on precise medicine has increased the demand for timely diagnosis and frequent monitoring of chronic diseases. The recent pandemic of severe acute respiratory syndrome coronavirus 2 has also created a need for rapid detection and surveillance of viral infections. Electrochemical biosensors based on nanomaterials have shown great potential in detecting biomarkers in point-of-care settings. This study critically reviews the recent advances in electrochemical sensors for salivary protein detection, emphasizing the role of nanomaterials in enhancing analytical performance and reliability of the test. It also identifies the critical factors for further modernization of nanomaterial-based electrochemical sensors.
Review
Acoustics
Zhaochu Yang, Guangcan Yang, Yongqing He, Zhongyuan Shi, Tao Dong
Summary: Fuel droplet evaporation plays a vital role in the generation of flammable mixtures in thermal engines. Traditional techniques involving boundaries to study droplet evaporation, such as suspended wires, can be influenced by their presence. Ultrasonic levitation offers a non-contact and non-destructive alternative to study droplet evaporation without interfering with droplet shape and heat transfer. This review paper explores the effects of acoustic fields on levitated droplets, the evaporation characteristics of acoustically levitated droplets, and the potential limitations of ultrasonic suspension methods for droplet evaporation, providing valuable references for future studies.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Thermodynamics
Zhongyuan Shi, Tao Dong, Zhaochu Yang
Summary: This research investigated the local heat transfer coefficient measurement using temperature oscillation induced by periodic thermal perturbation, usually with a Gaussian laser beam. It compared the impact of spikiness with an analytical model for dimensional analysis. The statistically more robust technique that relies on the linearity of the spatial phase distribution of the test point array was preferred when the target Biot number approaches unity. The preferred upper limit for thermographic scanning was discussed for simplifying later data processing.
CASE STUDIES IN THERMAL ENGINEERING
(2023)