期刊
SENSORS
卷 12, 期 11, 页码 14307-14314出版社
MDPI
DOI: 10.3390/s121114307
关键词
N-acylhomoserine lactone; N-dodecanoyl-L-homoserine lactone (C12-HSL); oral cavity; posterior dorsal surface; quorum sensing; tongue
资金
- University of Malaya [A000001-50001, RG033/09HTM]
We report the isolation of N-acyl homoserine lactone-producing Enterobacter sp. isolate T1-1 from the posterior dorsal surfaces of the tongue of a healthy individual. Spent supernatants extract from Enterobacter sp. isolate T1-1 activated the biosensor Agrobacterium tumefaciens NTL4(pZLR4), suggesting production of long chain AHLs by these isolates. High resolution mass spectrometry analysis of these extracts confirmed that Enterobacter sp. isolate T1-1 produced a long chain N-acyl homoserine lactone, namely N-dodecanoyl-homoserine lactone (C12-HSL). To the best of our knowledge, this is the first isolation of Enterobacter sp., strain T1-1 from the posterior dorsal surface of the human tongue and N-acyl homoserine lactones production by this bacterium.
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