Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation

The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity

(2014) Stéphane Chevrier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adjuvant-specific regulation of long-term antibody responses by ZBTB20

(2014) Yinan Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A simple and safe technique for longitudinal bone marrow aspiration in cynomolgus and rhesus macaques

(2014) Mats Spångberg et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Inflammasome-Dependent and -Independent IL-18 Production Mediates Immunity to the ISCOMATRIX Adjuvant

(2014) N. S. Wilson et al.   JOURNAL OF IMMUNOLOGY

Toll-Like Receptor 7/8 (TLR7/8) and TLR9 Agonists Cooperate To Enhance HIV-1 Envelope Antibody Responses in Rhesus Macaques

(2014) M. A. Moody et al.   JOURNAL OF VIROLOGY

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

(2014) K. Tran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of multiple adjuvants on the stability and immunogenicity of a clade C HIV-1 gp140 trimer

(2014) Joseph P. Nkolola et al.   VACCINE

Matrix MTMadjuvanted virosomal H5N1 vaccine induces balanced Th1/Th2 CD4+T cell responses in man

(2014) Gabriel K Pedersen et al.   Human Vaccines & Immunotherapeutics

Peptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles

(2013) Bianca R. Mothé et al.   IMMUNOGENETICS

Polyinosinic-Polycytidylic Acid Is the Most Effective TLR Adjuvant for SIV Gag Protein-Induced T Cell Responses In Nonhuman Primates

(2013) H. Park et al.   JOURNAL OF IMMUNOLOGY

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

(2013) J.-P. Julien et al.   SCIENCE

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

(2013) D. Lyumkis et al.   SCIENCE

CpG ODN and ISCOMATRIX Adjuvant: A Synergistic Adjuvant Combination Inducing Strong T-Cell IFN-γResponses

(2013) Michael J. McCluskie et al.   Biomed Research International

Distinct TLR adjuvants differentially stimulate systemic and local innate immune responses in nonhuman primates

(2012) M. Kwissa et al.   BLOOD

HIV-1 gp120 Impairs the Induction of B Cell Responses by TLR9-Activated Plasmacytoid Dendritic Cells

(2012) N. P. Y. Chung et al.   JOURNAL OF IMMUNOLOGY

Immunization of Macaques With Soluble HIV Type 1 and Influenza Virus Envelope Glycoproteins Results in a Similarly Rapid Contraction of Peripheral B-Cell Responses After Boosting

(2012) Christopher Sundling, Paola Martinez, Martina Soldemo, Mats Spångberg, Karin Lövgren Bengtsson, Linda Stertman, Mattias N. E. Forsell et al.   JOURNAL OF INFECTIOUS DISEASES

ISCOMATRIX: a novel adjuvant for use in prophylactic and therapeutic vaccines against infectious diseases

(2012) A. Baz Morelli et al.   JOURNAL OF MEDICAL MICROBIOLOGY

High-Resolution Definition of Vaccine-Elicited B Cell Responses Against the HIV Primary Receptor Binding Site

(2012) C. Sundling et al.   Science Translational Medicine

ADCC Develops Over Time during Persistent Infection with Live-Attenuated SIV and Is Associated with Complete Protection against SIVmac251 Challenge

(2012) Michael D. Alpert et al.   PLoS Pathogens

ISCOM technology-based Matrix M™ adjuvant: success in future vaccines relies on formulation

(2011) Karin Lövgren Bengtsson et al.   Expert Review of Vaccines

Human and rhesus plasmacytoid dendritic cell and B-cell responses to Toll-like receptor stimulation

(2011) Cornelia Gujer et al.   IMMUNOLOGY

ISCOMATRIX vaccines mediate CD8+ T-cell cross-priming by a MyD88-dependent signaling pathway

(2011) Nicholas S Wilson et al.   IMMUNOLOGY AND CELL BIOLOGY

Recombinant glycoprotein B vaccine formulation with Toll-like receptor 9 agonist and immune-stimulating complex induces specific immunity against multiple strains of cytomegalovirus

(2011) V. Dasari et al.   JOURNAL OF GENERAL VIROLOGY

Targeting TLRs Expands the Antibody Repertoire in Response to a Malaria Vaccine

(2011) S. R. Wiley et al.   Science Translational Medicine

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

(2010) Christopher Sundling et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunization with Wild-Type or CD4-Binding-Defective HIV-1 Env Trimers Reduces Viremia Equivalently following Heterologous Challenge with Simian-Human Immunodeficiency Virus

(2010) C. Sundling et al.   JOURNAL OF VIROLOGY

Breadth of Neutralizing Antibodies Elicited by Stable, Homogeneous Clade A and Clade C HIV-1 gp140 Envelope Trimers in Guinea Pigs

(2010) J. P. Nkolola et al.   JOURNAL OF VIROLOGY

Protection of macaques against vaginal SHIV challenge by systemic or mucosal and systemic vaccinations with HIV-envelope

(2009) Susan W Barnett et al.   AIDS

The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali

(2009) Boubacar Traore et al.   VACCINE

Human Immunodeficiency Virus Type 1 Env Trimer Immunization of Macaques and Impact of Priming with Viral Vector or Stabilized Core Protein

(2008) A. Morner et al.   JOURNAL OF VIROLOGY

Differential CD4+ versus CD8+ T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates

(2008) P. Mooij et al.   JOURNAL OF VIROLOGY

B Cell Recognition of the Conserved HIV-1 Co-Receptor Binding Site Is Altered by Endogenous Primate CD4

(2008) Mattias N. E. Forsell et al.   PLoS Pathogens