期刊
SEMINARS IN REPRODUCTIVE MEDICINE
卷 32, 期 1, 页码 43-49出版社
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0033-1361822
关键词
vaginal microbiota; bacterial vaginosis; pelvic inflammatory disease
资金
- NIH Intramural Research Program in Reproductive and Adult Endocrinology
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [ZIEHD008737] Funding Source: NIH RePORTER
Female genital tract microbiota play a crucial role in maintaining health. Disequilibrium of the microbiota has been associated with increased risk of pelvic infections. In recent years, culture-independent molecular techniques have expanded understanding of the composition of genital microbiota and the dynamic nature of the microbiota. There is evidence that upper genital tract may not be sterile and may harbor microflora in the physiologic state. The isolation of bacterial vaginosis-associated organisms in women with genital infections establishes a link between pelvic infections and abnormal vaginal flora. With the understanding of the composition of the microbiota in healthy and diseased states, the next logical step is to identify the function of the newly identified microbes. This knowledge will further expand our understanding of the causation of pelvic infections, which may lead to more effective prevention and treatment strategies.
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