Article
Multidisciplinary Sciences
Pi-Hsia Lee, Ting-Ting Yeh, Hsin-Yen Yen, Wan-Ling Hsu, Valeria Jia-Yi Chiu, Shu-Chun Lee
Summary: The combination of stroke and cognitive impairment increases the severity of ADL disabilities in older adults. While the stroke group and cognitive impairment group showed similarities in the number and difficulty of tasks, differences were found in specific areas of difficulty. A hierarchy of ADLs was observed in all groups, indicating the need for interventions focusing on secondary prevention of dementia and improving motor functional capacity.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Hyeji Jung, Dongsu Lee, Heejung You, Myungha Lee, Hyeonho Kim, Eunji Cheong, Ji Won Um
Summary: This study investigates the temporal sequence from microglial activation to synaptic dysfunction and cognitive behavior induced by neuroinflammation in mice. It demonstrates that neuroinflammation induces microglia activation, GABAergic synaptic deficits, and prolonged memory impairment.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Multidisciplinary
Xiaoyu Li, Yifei Pei, Ying Zhao, Haoqiang Song, Jianhui Zhao, Lei Yan, Hui He, Siyu Lu, Xiaobing Yan
Summary: This study proposes the use of carbon dots to improve the uniformity of memristor parameters, resulting in more stable and efficient devices. Furthermore, carbon dots based memristor devices are able to simulate various neural network learning rules and successfully achieve simulation of the preview and review learning method.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Clinical Neurology
Henderyke. A. A. Wonink, Willeke. J. J. Kruithof, H. Stephan Goedee, Anita Beelen
Summary: This study examined the self-reported activity and participation limitations in patients with CIDP and MMN, and identified associated factors. The results showed that CIDP patients commonly experienced limitations in activities and participation, while MMN patients had fewer limitations. Fatigue, pain, and resilience were found to be associated with activity limitations and satisfaction with participation in CIDP patients.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Multidisciplinary Sciences
Itsuki Doi, Weibing Deng, Takashi Ikegami
Summary: Social entrainment is crucial for the functioning of bee colonies. Through analysis of tracking data from around 1000 honeybees, it was observed that honeybees exhibit synchronized bursting behavior during locomotion. These bursts, which occur spontaneously, are possibly a result of intrinsic interactions among the bees. Physical contact was found to be a mechanism for these bursts. Pioneer bees, linked to foraging behavior and waggle dancing, play a key role in spreading external information within the hive. Transfer entropy analysis demonstrated that information flows from pioneer bees to non-pioneer bees, indicating that bursting behavior is influenced by foraging and information propagation, promoting integrated group behavior among individuals.
SCIENTIFIC REPORTS
(2023)
Article
Economics
Victoria Ateca-Amestoy, Arantza Ugidos-Olazabal
Summary: Education, income, and having young children are found to be main factors influencing the probability of spouses participating in the same cultural and sports activities. Both male and female education have a positive effect on these probabilities, but there is no statistically significant difference.
Article
Cell Biology
Li-Jie Yang, Wei Wu, Wan-Rong Jiang, Cheng-Liang Zhu, Zhao -Hui Yao
Summary: Chronic cerebral hypoperfusion (CCH)-mediated cognitive impairment is a global problem. In this study, we found that RasGRF1 expression levels decreased after CCH, while the inhibition of miRNA-323-3p upregulated RasGRF1 expression and improved cognitive impairments such as spatial learning and memory.
Article
Geriatrics & Gerontology
Hongting Ning, Hua Zhang, Zhihai Xie, Weihong Jiang, Shaobing Xie
Summary: This study investigated the mediating effect of social participation and depressive symptoms on the relationship between hearing impairment and frailty using data from the China Health and Retirement Longitudinal Study. The results showed that hearing impairment, social participation, and depressive symptoms were associated with the incidence of frailty. Both social participation and depressive symptoms mediated the relationship between hearing impairment and frailty, albeit in different ways depending on the participants' hearing status. Integrated intervention measures, such as hearing screenings, promoting social participation, and improving depressive symptoms, are suggested to prevent frailty.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Psychology, Multidisciplinary
Giulio E. Lancioni, Nirbhay N. Singh, Mark F. O'Reilly, Jeff Sigafoos, Gloria Alberti, Alessandra Fiore
Summary: A new technology-aided program aimed at helping individuals with intellectual and multiple disabilities in leisure, communication, and daily activities was assessed in this study. The results suggested that the program could be a useful tool for improving participants' condition in basic areas of daily life.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Pavan Thapak, Zhe Ying, Victoria Palafox-Sanchez, Guanglin Zhang, Xia Yang, Fernando Gomez-Pinilla
Summary: Traumatic brain injury (TBI) impairs cellular energy demand, compromising neuronal function and plasticity. This study demonstrates that the mitochondrial activator humanin (HN) can counteract the reduction in mitochondrial bioenergetics caused by TBI, restore memory function and synaptic protein levels, and suppress inflammation and astrocyte proliferation. HN plays an integral role in normalizing fundamental aspects of TBI pathology.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2024)
Article
Clinical Neurology
Sara Becker, Claire Pauly, Michael Lawton, Geraldine Hipp, Francesca Bowring, Patricia Sulzer, Michele Hu, Rejko Krueger, Thomas Gasser, Inga Liepelt-Scarfone
Summary: The study suggests that self-reported ADL impairments assessed by the FAQ are related to the severity of cognitive impairment in PD, showing moderate specificity in differentiating cognitive status in PD patients.
NEUROLOGICAL SCIENCES
(2022)
Article
Multidisciplinary Sciences
Matthew T. Rich, Samantha J. Worobey, Sharvari Mankame, Zhiping P. Pang, Sarah E. Swinford-Jackson, R. Christopher Pierce
Summary: Cocaine exposure in male rats affects fear-associated behaviors in their offspring, with enhanced freezing behavior in female progeny and enhanced expression of cue-conditioned fear during extinction in male progeny. The absence of long-term potentiation (LTP) in the basolateral amygdala (BLA) suggests synaptic plasticity deficits in male offspring of cocaine-exposed sires.
Article
Cell Biology
Zhao-Hui Yao, Jing Wang, Jing-Ping Yuan, Kai Xiao, Shao-Feng Zhang, Yan-Chun Xie, Jun-Hua Mei
Summary: EGB761 treatment may improve cognitive function impairment induced by CCH by affecting synaptic plasticity, synaptic degeneration, and axon demyelination.
Review
Neurosciences
Xiansu Chi, Liuding Wang, Hongxi Liu, Yunling Zhang, Wei Shen
Summary: Post-stroke cognitive impairment is a major complication of stroke, characterized by cognitive dysfunction that directly affects quality of life. This review examines the pathological damage of stroke on synaptic plasticity, analyzes changes in synaptic plasticity in post-stroke cognitive impairment, and summarizes commonly used Chinese herbal drugs that can regulate synaptic plasticity. The review aims to establish the relationship between post-stroke cognitive impairment and synaptic plasticity, provide new insights for future exploration of its mechanism, compile evidence for the use of Chinese herbal drugs in treating post-stroke cognitive impairment, and lay the foundation for the development of novel formulas.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Psychology, Multidisciplinary
Laia Delfa-Lobato, Joan Guardia-Olmos, Maria Feliu-Torruella
Summary: This study explored the benefits of different modalities of cultural activities for cognitively impaired individuals, finding significant improvements in general cognition, quality of life, emotional wellbeing, socialization, and communication. However, there was not enough evidence to prove memory, language, or daily functioning improvements attributable to cultural interventions.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Neurosciences
Allen W. Brown, Anne M. Moessner, Thomas F. Bergquist, Kathryn S. Kendall, Nancy N. Diehl, Jay Mandrekar
Article
Critical Care Medicine
Regina S. Eum, Ronald T. Seel, Richard Goldstein, Allen W. Brown, Thomas K. Watanabe, Nathan D. Zasler, Elliot J. Roth, Ross D. Zafonte, Mel B. Glenn
JOURNAL OF NEUROTRAUMA
(2015)
Article
Clinical Neurology
Allen W. Brown, Terry M. Therneau, Billie A. Schultz, Paulette M. Niewczyk, Carl V. Granger
Article
Rehabilitation
Allen W. Brown, Thomas K. Watanabe, Jeanne M. Hoffman, Kathleen R. Bell, Sylvia Lucas, Sureyya Dikmen
Article
Rehabilitation
Sarah Eby, Heng Zhao, Pengfei Song, Barbara J. Vareberg, Randall Kinnick, James F. Greenleaf, Kai-Nan An, Shigao Chen, Allen W. Brown
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2016)
Article
Clinical Neurology
Anne C. Ritter, Amy K. Wagner, Anthony Fabio, Mary Jo Pugh, William C. Walker, Jerzy P. Szaflarski, Ross D. Zafonte, Allen W. Brown, Flora M. Hammond, Tamara Bushnik, Douglas Johnson-Greene, Timothy Shea, Jason W. Krellman, Joseph A. Rosenthal, Laura E. Dreer
Article
Clinical Neurology
Anne C. Ritter, Amy K. Wagner, Jerzy P. Szaflarski, Maria M. Brooks, Ross D. Zafonte, Mary Jo V. Pugh, Anthony Fabio, Flora M. Hammond, Laura E. Dreer, Tamara Bushnik, William C. Walker, Allen W. Brown, Doug Johnson-Greene, Timothy Shea, Jason W. Krellman, Joseph A. Rosenthal
Article
Public, Environmental & Occupational Health
Gordon W. Fuller, Jeanine Ransom, Jay Mandrekar, Allen W. Brown
Article
Clinical Neurology
Regina S. Eum, Allen W. Brown, Thomas K. Watanabe, Nathan D. Zasler, Richard Goldstein, Ronald T. Seel, Elliot J. Roth, Ross D. Zafonte, Mel B. Glenn
JOURNAL OF HEAD TRAUMA REHABILITATION
(2017)
Article
Clinical Neurology
Jennifer A. Bogner, Gale G. Whiteneck, Jessica MacDonald, Shannon B. Juengst, Allen W. Brown, Angela M. Philippus, Jennifer H. Marwitz, Jeannie Lengenfelder, Dave Mellick, Patricia Arenth, John D. Corrigan
JOURNAL OF HEAD TRAUMA REHABILITATION
(2017)
Review
Rehabilitation
Ryan C. Kruse, Zhuo Li, Cara C. Prideaux, Allen W. Brown
Article
Clinical Neurology
William C. Walker, Jennifer H. Marwitz, Amber R. Wilk, Jessica M. Ketchum, Jeanne M. Hoffman, Allen W. Brown, Sylvia Lucas
Article
Public, Environmental & Occupational Health
Dmitry Esterov, Erica Bellamkonda, Jay Mandrekar, Jeanine E. Ransom, Allen W. Brown
Summary: This study found that the increased risk of death after TBI only existed during the first 6 months after injury, and the difference was mainly due to external causes.
Review
Public, Environmental & Occupational Health
Michael A. Sperl, Dmitry Esterov, Jeanine E. Ransom, Michelle M. Mielke, Julie E. Witkowski, Allen W. Brown
Summary: The long-term risk of stroke after traumatic brain injury (TBI) is relatively high in patients aged 40 years and older. Regular assessment of long-term vascular risk and implementation of disease prevention strategies are needed for TBI patients.
Proceedings Paper
Engineering, Biomedical
Shane M. Anderson, Timothy H. Riehle, Patrick A. Lichter, Allen W. Brown, Dorin Panescu
2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
(2015)
