期刊
SEMINARS IN FETAL & NEONATAL MEDICINE
卷 19, 期 6, 页码 331-337出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.siny.2014.09.005
关键词
Congenital diaphragmatic hernia; Prenatal ultrasound; Magnetic resonance imaging; Lung-to-head ratio
类别
Over the past 20 years, prenatal detection of congenital diaphragmatic hernia (CDH) has improved worldwide, reaching up to 60% in Europe. Pulmonary hypoplasia and persistent pulmonary hypertension are the two main determinants of neonatal mortality and morbidity, so new tools have been focused on their evaluation. Fetal surgery for severe cases requires proper evaluation of the prognosis of fetuses with CDH. Observed-to-expected lung-to-head ratio, liver position, and total lung volume measured by magnetic resonance are the prognostic factors most often used, and have been shown to correlate not only with neonatal mortality but also with morbidity. In daily practice, pulmonary hypertension by itself, although most often associated with lung hypoplasia, is more difficult to predict. (C) 2014 Published by Elsevier Ltd.
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