Article
Chemistry, Multidisciplinary
Hanyu Qian, Eric Mclamore, Nikolay Bliznyuk
Summary: Reuse of alternative water sources for irrigation is a sustainable approach to reduce water gaps and increase food production, but it poses a risk of bacterial contamination. This study developed a statistical machine-learning framework to accurately predict the concentration of pathogenic organisms, such as E. coli, in untreated surface water using an impedimetric electrochemical aptasensor. The framework improved prediction accuracy and can be used for rapid decision support in hydroponic irrigation.
Article
Multidisciplinary Sciences
Delia Tomoiaga, Jaclyn Bubnell, Liam Herndon, Paul Feinstein
Summary: Griffith proposed the concept of DNA transfer between bacteria in 1928. Researchers have demonstrated that E. coli can accept multiple plasmids simultaneously, resulting in widespread aclonality during colony development. Tracking clonally related bacteria allows for mosaic analysis of gene function. Additionally, it was discovered that clonally related bacterium rods self-organize fractally and can remain linked during colony growth, presenting a potential target for controlling microbiota growth.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Analytical
Haoran Li, Yubo Wang, Yaohua Li, Wei Wang
Summary: The new method successfully quantifies bacterial viability at a single-cell level using optical tweezers, holding potential in antibiotic susceptibility testing, drug screening, and rapid diagnostics.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Haoran Li, Yubo Wang, Yaohua Li, Wei Wang
Summary: This study presents a new label-free bacterial viability assay based on optical tweezers technology, which quantifies bacterial viability by monitoring bacterial nanomotion in the optical traps. The assay is characterized by short time consumption, simple sample preparations, and no cytotoxicity, making it a reliable method for assessing bacterial viability at the single-cell level.
ANALYTICAL CHEMISTRY
(2022)
Review
Infectious Diseases
Fabio P. Sellera, Luciano C. B. A. Da Silva, Nilton Lincopan
Summary: The COVID-19 pandemic has deepened the relationships between humans and companion animals, leading to an increase in the use of antibiotics and biocides worldwide. Data from global surveillance studies show a linear trend in increasing carbapenem resistance among Gram-negative pathogens in companion animals, with humans potentially acquiring carbapenemase-producing bacteria through contact with infected animals or contaminated environments. The rapid spread of WHO critical priority carbapenemase-producing pathogens in companion animals presents a One Health challenge for the post-pandemic world.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Multidisciplinary Sciences
Muhammad Tanveer Munir, Nattar Maneewan, Julien Pichon, Mohammed Gharbia, Ismael Oumarou-Mahamane, Jessica Baude, Chantal Thorin, Didier Lepelletier, Patrice Le Pape, Matthieu Eveillard, Mark Irle, Helene Pailhories, Florence Aviat, Christophe Belloncle, Michel Federighi, Laurence Dubreil
Summary: The study used mCherry Staphylococcus aureus as a model bacterium and employed a confocal spectral laser microscope (CSLM) to characterize wood surfaces. It was found that more bacteria were present near the surface of the LT face wood, and this methodology shows promise as a tool for hygienic safety evaluation.
SCIENTIFIC REPORTS
(2021)
Article
Nutrition & Dietetics
Yunqi Cheng, Hongping Chen
Summary: This review highlights the essential role of zinc in enzyme activity regulation, particularly through zinc metalloenzymes, and its significance in physiological processes and diseases, providing insights for novel treatment strategies in the future.
Article
Multidisciplinary Sciences
James Y. Tan, Tatyana E. Saleski, Xiaoxia Nina Lin
Summary: Co-cultivation in microfluidic droplets is a versatile tool for studying microbial communities, and the droplet size is a critical parameter that affects various aspects of community dynamics.
Article
Chemistry, Physical
Dan Wu, Wenming Zhang, Baihe Fu, Zhonghai Zhang
Summary: Biological hydrogen production has great potential in the field of renewable energy, and this research demonstrates the significant enhancement of biological hydrogen production through solar-light induction and intra-cellular inorganic-biological hybrid system optimization.
Article
Environmental Sciences
Sankalp Arya, Alexander Williams, Saul Vazquez Reina, Charles W. Knapp, Jan-Ulrich Kreft, Jon L. Hobman, Dov J. Stekel
Summary: Many antibiotic resistance genes co-occur with resistance genes for transition metals, such as copper, zinc, or mercury. Mathematical modelling is used to predict minimal co-selective concentrations for metals, aiding in the mitigation of risks of antimicrobial resistance.
ENVIRONMENTAL POLLUTION
(2021)
Article
Chemistry, Multidisciplinary
Nicholas G. S. McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin-Hill, Daniel Linzel, Chihaya Yamada, Takatoshi Arakawa, Akihiro Ishiwata, Yukishige Ito, Gijsbert A. van der Marel, Jeroen D. C. Codee, Shinya Fushinobu, Herman S. Overkleeft, Carme Rovira, Gideon J. Davies
Summary: The discovery of zinc-dependent retaining glycoside hydrolases presents unresolved mechanistic questions, particularly the controversy surrounding the proposed mechanism involving a zinc-coordinated cysteine nucleophile and a thioglycosyl enzyme intermediate. A synthesized beta-l-arabinofuranosidase inhibitor reacts exclusively with the cysteine thiol catalytic nucleophiles of GH families 127 and 146, supporting further research into the breakdown of the thioglycosyl enzyme intermediate. X-ray crystal structures and simulations provide insight into the mechanisms of zinc-coordinated cysteine as the catalytic nucleophile and the energetics of this unique metalloenzyme clan.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Multidisciplinary Sciences
Chae Won Kang, Hyun Gyu Lim, Jaehyuk Won, Sanghak Cha, Giyoung Shin, Jae-Seong Yang, Jaeyoung Sung, Gyoo Yeol Jung
Summary: In this study, the authors developed a synthetic adaptation strategy to improve the production of a microbial consortium. By introducing a genetic circuit in one of the strains, they were able to control the production of a specific compound and acclimate the consortium for higher production.
NATURE COMMUNICATIONS
(2022)
Article
Agriculture, Dairy & Animal Science
Guillermo Ramis, Francisco Murciano, Juan Orengo, Belen Gonzalez-Guijarro, Amanda Cuellar-Flores, Daniel Serrano, Antonio Munoz Luna, Pedro Sanchez-Uribe, Laura Martinez-Alarcon
Summary: Zinc oxide is widely used to prevent and control post-weaning Escherichia coli diarrhoea in piglets, sometimes in combination with oral E. coli vaccines. This study assessed the influence of zinc oxide in piglet feed on immune activation, intestinal integrity, secretory IgA production, and E. coli excretion post-vaccination. The presence of zinc oxide did not significantly affect the immune response or soluble IgA production in orally vaccinated animals.
Article
Biochemistry & Molecular Biology
Marta Cobo-Simon, Rowan Hart, Howard Ochman
Summary: Escherichia coli has been a vital model organism for studying various aspects of genetics, evolution, molecular biology, and pathogenesis. However, the classification of strains belonging to this species is inconsistent and unstable due to changes in the characteristics and criteria used to differentiate bacterial species. Furthermore, many isolates designated as E. coli are genetically more closely related to Shigella strains, resulting in the inclusion of the entire Shigella genus within the single species E. coli. By applying the biological species concept (BSC) and evaluating complete genomes, we found minimal barriers to gene flow among E. coli and Shigella strains, indicating the need for a more precise classification system.
MOLECULAR BIOLOGY AND EVOLUTION
(2023)
Article
Chemistry, Analytical
Tianyu Jiang, Xingye Yang, Geng Li, Xiaohan Zhao, Tao Sun, Rolf Mueller, Hailong Wang, Minyong Li, Youming Zhang
Summary: This study developed a live, EcN-based imageable vehicle for noninvasive in vivo bioluminescence imaging in live mice, providing a valuable tool for tracking bacteria and potentially assisting in cancer therapy.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Fut (Kuo) Yang, Aleksander Cholewinski, John F. Honek, Wei Wei, Luzhu Xu, Wei Zhang, Michael A. Pope, Boxin Zhao
Summary: By manipulating the molecular conformation, this study enhances interfacial adhesion between a coating and hydrogels, demonstrating that imparting memory is a general and facile noncovalent approach for enhancing interfacial adhesion, which can be used for bonding materials across different length scales.
MATERIALS HORIZONS
(2022)
Article
Food Science & Technology
Jirachaya Piseskul, Uthaiwan Suttisansanee, Chaowanee Chupeerach, Chanakan Khemthong, Sirinapa Thangsiri, Piya Temviriyanukul, Yuraporn Sahasakul, Chalat Santivarangkna, Rungrat Chamchan, Amornrat Aursalung, Nattira On-nom
Summary: In this study, the optimal conditions for enzyme-assisted mechanical extraction of Hodgsonia heteroclita seed oil were determined using response surface methodology. The results showed that a mixture of Flavourzyme (R) and Viscozyme (R) at a ratio of 1:1 was the most efficient enzyme. The predicted maximum oil yield was 46.44% under the conditions of 2.98% enzyme loading, 48°C incubation temperature, and 76 minutes of incubation time. The seed oil obtained from heat and enzymatic pretreatments had the desired chemical properties and contained high levels of delta-tocopherol and omega-6 fatty acids.
Article
Food Science & Technology
Nattira On-Nom, Kanoknad Khaengamkham, Aikkarach Kettawan, Thanaporn Rungruang, Uthaiwan Suttisansanee, Piya Temviriyanukul, Pattaneeya Prangthip, Chaowanee Chupeerach
Summary: Hypertension leads to oxidative stress, inflammation, and fibrosis. Parboiled germinated brown rice (PGBR) reduces oxidative stress and inflammation. PGBR contains more bioactive compounds than brown rice and white rice. However, research on the anti-hypertensive effects of PGBR is lacking.
Article
Biochemistry & Molecular Biology
Woorawee Inthachat, Piya Temviriyanukul, Nattira On-Nom, Panyaporn Kanoongon, Sirinapa Thangsiri, Chaowanee Chupeerach, Uthaiwan Suttisansanee
Summary: In this study, response surface methodology (RSM) and Box-Behnken design (BBD) were used to optimize the extraction conditions of C. maxima albedo from agricultural waste. The optimized conditions were 50% aqueous ethanol with a temperature of 30 degrees C for 4 hours, resulting in significant amounts of phytochemicals in the extract. The extract exhibited inhibitory activities against key enzymes related to Alzheimer's disease, obesity, and diabetes, and showed no mutagenicity properties.
Article
Biochemistry & Molecular Biology
Anton M. van der Ven, Hawa Gyamfi, Uthaiwan Suttisansanee, Muhammad S. Ahmad, Zhengding Su, Robert M. Taylor, Amanda Poole, Sorina Chiorean, Elisabeth Daub, Taylor Urquhart, John F. Honek
Summary: Currently, there is great interest in using multisubunit cage proteins and spherical virus capsids for bionanotechnology, drug delivery, and diagnostic imaging applications. This study focuses on expanding the capabilities of ferritin proteins by developing new approaches to encapsulate molecular cargo. Two strategies, including the use of histidine-tag peptide fusion sequences and heme-dependent cassette strategy, were explored to control encapsulation. The research presents novel strategies to control a diverse set of molecular encapsulations and adds sophistication to internal protein cavity engineering.
Article
Nutrition & Dietetics
Linh Khanh Luu, Sirinapa Thangsiri, Yuraporn Sahasakul, Amornrat Aursalung, Woorawee Inthachat, Piya Temviriyanukul, Nattira On-Nom, Chaowanee Chupeerach, Uthaiwan Suttisansanee
Summary: This study aims to provide more biological information about N. hypoleucum Kurz tree by examining its nutritional composition, organic acid and phenolic profiles, as well as its health properties against several civilization diseases through inhibiting key enzymes. The fruit's aril part contains abundant nutrients and has characteristics of combating certain diseases, and the other parts of the fruit also contain potential phenolics and key enzyme inhibitors.
Article
Food Science & Technology
Kanokporn Julai, Pimnapanut Sridonpai, Chitraporn Ngampeerapong, Karaked Tongdonpo, Uthaiwan Suttisansanee, Wantanee Kriengsinyos, Nattira On-Nom, Nattapol Tangsuphoom
Summary: This study investigated the effects of extraction and evaporation methods on various properties of the syrups prepared from Barhi dates. Extraction of date juice with the aid of enzymes significantly enhanced production yield, total phenolic content, and antioxidant activities. Syrups prepared without enzyme application had higher viscosity than those prepared from enzyme-assisted extracted juices. Vacuum evaporation produced syrups with lighter color and inferior antioxidant properties.
Article
Food Science & Technology
Nur Hadiyani Zakaria, Kanyawee Whanmek, Sirinapa Thangsiri, Wimonphan Chathiran, Warangkana Srichamnong, Uthaiwan Suttisansanee, Chalat Santivarangkna
Summary: The trend of cold brew coffee (CBC) is increasing globally, but there is limited research on this popular beverage. This study aimed to investigate the effects of brewing conditions on the physicochemical properties of CBC and compare it with coffee brewed by the French Press method. The results showed that water temperature, coffee-to-water ratio, and coffee mesh size significantly influenced the total dissolved solids (TDS) of CBC. At similar TDS, CBC had higher caffeine content, volatile compounds, and organic acids compared to the French Press coffee.
Article
Food Science & Technology
Kanokwan Manoonphol, Uthaiwan Suttisansanee, Chadamas Promkum, Chaniphun Butryee
Summary: This study aimed to investigate the optimum thermal condition for developing Thai black garlic with high S-allyl cysteine (SAC) content and compared the total phenolic contents and antioxidant activities of Thai fresh garlic, Thai black garlic, and their powder forms. The results indicated that the optimum thermal condition for producing Thai fresh garlic and Chinese fresh garlic with high SAC content was 70 degrees Celsius and a relative humidity of 80% for 12 days in an industrial fermentation chamber.
Article
Plant Sciences
Nattira On-nom, Sirinapa Thangsiri, Woorawee Inthachat, Piya Temviriyanukul, Yuraporn Sahasakul, Chaowanee Chupeerach, Kanchana Pruesapan, Piyapat Trisonthi, Dalad Siriwan, Uthaiwan Suttisansanee
Summary: Sacred lotus is widely used as a commercial product in Asian countries due to its high contents of secondary metabolites. This study investigated the seasonal variation of different sacred lotus parts and found that the aqueous extract of stamen exhibited potentially high total phenolic contents, antioxidant activities, and enzyme inhibitions compared to other parts. The phenolic content and biochemical activities were highest when stamen was harvested at the beginning of the rainy season.
Article
Multidisciplinary Sciences
Uthaiwan Suttisansanee, Parunya Thiyajai, Woorawee Inthachat, Kanchana Pruesapan, Khanitha Wongwathanarat, Somsri Charoenkiatkul, Yuraporn Sahasakul, Piya Temviriyanukul
Summary: This study investigated the mineral, vitamin, and carotenoid contents of 20 vegetables collected and managed based on the recommendations of the Department of Agriculture, Ministry of Agriculture and Cooperatives, Thailand. The results showed that these vegetables exhibited similar energy levels, mainly from high carbohydrate content, while protein and fat levels were low. The nutritional and carotenoid compositions of the vegetables were minimally affected by the location of sample collection.
Article
Green & Sustainable Science & Technology
Nattira On-nom, Uthaiwan Suttisansanee, Wimonphan Chathiran, Somsri Charoenkiatkul, Parunya Thiyajai, Warangkana Srichamnong
Summary: The aim of this study was to explore the current knowledge and practice of agrobiodiversity in improving nutrition and health. The study focused on wild mushrooms commonly consumed in Northeastern Thailand, studying their ecology, cooking and preservation methods, and folk remedies. The findings showed that these wild mushrooms can be used for both food and medicinal purposes, as they have high levels of sugars, glucans, and carbohydrates, and a low glycemic index.
Article
Food Science & Technology
Yuraporn Sahasakul, Amornrat Aursalung, Sirinapa Thangsiri, Piya Temviriyanukul, Woorawee Inthachat, Pirach Pongwichian, Kamontip Sasithorn, Uthaiwan Suttisansanee
Summary: Rice is a staple food crop for over half of the world's population, but drought and increased soil salinity as a result of climate change have negatively affected its nutritional compositions and biochemical properties. However, this study has shown that suitable fertilizers can improve rice quality even in soil with high salinity levels.
Article
Food Science & Technology
Nattira On-Nom, Prapatsorn Promdang, Woorawee Inthachat, Panyaporn Kanoongon, Yuraporn Sahasakul, Chaowanee Chupeerach, Uthaiwan Suttisansanee, Piya Temviriyanukul
Summary: The study developed nutritious snacks using response surface methodology (RSM) with mixture design, incorporating the small aquatic plant W. globosa. The snacks enriched with W. globosa powder showed significantly increased protein, essential amino acids, dietary fiber, as well as higher phytochemical contents and antioxidant activities compared to the control snack.
Article
Food Science & Technology
Woorawee Inthachat, Sirinapa Thangsiri, Chanakan Khemthong, Nattira On-Nom, Chaowanee Chupeerach, Yuraporn Sahasakul, Piya Temviriyanukul, Uthaiwan Suttisansanee
Summary: Oil extraction from Hodgsonia heteroclita seeds produces a biowaste called oilseed cake powder (OCP) that can be utilized for its antioxidant and health-promoting properties. This study optimized the extraction process for Hodgsonia heteroclita OCP and investigated its phytochemical profiles, antioxidant activities, and enzyme inhibitory activities.
Review
Cell Biology
Alyssa Kearly, Andrew D. L. Nelson, Aleksandra Skirycz, Monika Chodasiewicz
Summary: Stress Granules (SGs) and Processing-bodies (P-bodies) are important biomolecular condensates that play crucial roles in maintaining mRNA balance and regulating stress responses. They are composed of proteins and RNAs involved in translation, protein folding, and energy metabolism.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
P. Lemonnier, T. Lawson
Summary: Stomatal conductance plays a crucial role in determining CO2 uptake and water loss in plants, affecting overall water status and productivity. However, the signals coordinating mesophyll demands for CO2, the role of chloroplasts in stomatal function, and other GC metabolic processes in stomatal function remain poorly understood.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Matteo Gionfriddo, Timothy Rhodes, Spencer M. Whitney
Summary: Rubisco is a key enzyme that facilitates the entry of CO2 into the biosphere, but its catalytic properties are slow and error-prone. More effective Rubisco variants have been discovered in certain algae, offering the potential to significantly improve crop productivity. However, incompatibilities in protein folding have hindered the transplantation of these variants into plants. Directed evolution is now being explored to enhance Rubisco catalysis.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Vittoria Clapero, Stephanie Arrivault, Mark Stitt
Summary: The Calvin-Benson cycle has undergone massive selection and co-evolution with carbon-concentrating mechanisms due to changing environmental factors. Metabolite profiling reveals species-specific variations in the operation of the cycle, indicating the influence of different modes of photosynthesis. Connectivity analysis identifies constraints and driving factors for cross-species diversity in the cycle.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Sukhbir Kaur, David D. Roberts
Summary: Thrombospondin-1 modulates cell behavior by interacting with components of the extracellular matrix and cell surface receptors. Its release and expression are influenced by injuries and various diseases, while its sustained presence in the extracellular space is regulated by receptor-mediated clearance. Thrombospondin-1 plays important roles in immune responses.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Richard P. Tucker, Josephine C. Adams
Summary: Thrombospondins (TSPs) play diverse roles in animals and have been found to belong to a superfamily that includes different subgroups such as mega-TSPs, sushi-TSPs, and poriferan-TSPs. Invertebrates encode a greater diversity of TSP superfamily members than vertebrates.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
James Petrik, Sylvia Lauks, Bianca Garlisi, Jack Lawler
Summary: Many cancers start with a small nest of transformed cells that can remain dormant. Thrombospondin-1 (TSP-1) initially promotes dormancy by suppressing angiogenesis, but over time, factors promoting angiogenesis become dominant and recruit various cells to form a complex tumor microenvironment. TSPs play a role in the proliferation, migration, and invasion of cells in the tumor microenvironment, as well as influencing the immune characteristics and phenotype of tumor-associated macrophages.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Hana Fakim, Christine Vande Velde
Summary: There has been increasing attention to the role of phase-separated biomolecular condensates, specifically stress granules, in neurodegenerative diseases like ALS. ALS-associated mutations in genes involved in stress granule assembly have been found, and stress granule proteins have been detected in pathological inclusions in ALS patient neurons. However, protein components of stress granules are also present in other physiological biomolecular condensates, which have not been adequately discussed in relation to ALS. This review explores the functions of TDP-43 and FUS in physiological condensates occurring in the nucleus and neurites beyond stress granules, and discusses the impact of ALS-linked mutations on their ability to phase separate and perform their functions in stress-independent biomolecular condensates.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Alexander Lin, Yogambha Ramaswamy, Ashish Misra
Summary: Smooth muscle cells, endothelial cells, and macrophages in blood vessels display remarkable heterogeneity, and their developmental origins may influence their plasticity. Unbiased single cell whole transcriptome analysis techniques are revolutionizing the understanding of cellular diversity and plasticity, providing insights for therapeutic research.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Elton P. Hudson
Summary: The Calvin Benson cycle plays a crucial role in the ecological and biotechnological aspects of bacteria. Recent studies have shed light on the regulation of this cycle in bacteria, with post-transcriptional and post-translational regulation being important in phototrophic bacteria, and transcriptional regulation being prominent in chemolithoautotrophic bacteria. Understanding the regulation of the Calvin Benson cycle has implications for enhancing CO2 fixation and improving the synthesis of desired products. Non-canonical cycles may offer potential benefits for industrial applications.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Xin-Guang Zhu, Haim Treves, Honglong Zhao
Summary: This paper discusses the major regulatory mechanisms over the Calvin Benson Cycle (CBC) that maintain homeostasis of metabolite levels. These mechanisms include redox regulation of enzymes, metabolite regulations (especially allosteric regulations), and balanced activities of enzymes. These regulatory mechanisms are crucial for maintaining high flux and photosynthetic efficiency in CBC.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Hunter C. Herriage, Yi-Ting Huang, Brian R. Calvi
Summary: Apoptosis prevents the inappropriate acquisition of extra copies of the genome, known as polyploidy, but the polyploid state can suppress apoptosis. The mechanisms linking apoptosis and polyploid cell cycles are still largely unknown, and studying the regulation of apoptosis in development and cancer could lead to more effective therapies.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Daniel Campbell, Steven Zuryn
Summary: Mitochondrial dynamics play a crucial role in regulating cellular and organismal homeostasis, impacting various aspects of an organism's healthspan. By studying the nematode Caenorhabditis elegans, a comprehensive understanding of the impact of mitochondrial dynamics on homeostasis over a lifetime can be obtained.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Diba Borgmann, Henning Fenselau
Summary: Maintaining blood glucose at an appropriate physiological level requires coordination of multiple organs and tissues, with the vagus nerve playing a key role in central control. Recent studies have revealed the cellular identity, neuroanatomical organization, and functional contributions of vagal neurons in the regulation of systemic glucose metabolism. These findings provide new insights into the precise roles of vagal neurons in coordinating glucose levels and offer potential avenues for treating glucose metabolism disorders.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)
Review
Cell Biology
Tatiana C. Coverdell, Stephen B. G. Abbott, John N. Campbell
Summary: In this article, we review how genetic technology and single-cell genomics are revealing the organizational principles of the efferent vagus in unprecedented detail.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2024)