Complex trait architecture: the pleiotropic model revisited

Simulation of Finnish Population History, Guided by Empirical Genetic Data, to Assess Power of Rare-Variant Tests in Finland

(2014) Sophie R. Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The deleterious mutation load is insensitive to recent population history

(2014) Yuval B Simons et al.   NATURE GENETICS

The Impact of Population Demography and Selection on the Genetic Architecture of Complex Traits

(2014) Kirk E. Lohmueller   PLoS Genetics

Evaluating empirical bounds on complex disease genetic architecture

(2013) Vineeta Agarwala et al.   NATURE GENETICS

Rates and Fitness Consequences of New Mutations in Humans

(2012) Peter D. Keightley   GENETICS

Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants

(2012) A. Keinan et al.   SCIENCE

The Original Michaelis Constant: Translation of the 1913 Michaelis–Menten Paper

(2011) Kenneth A. Johnson et al.   BIOCHEMISTRY

The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms

(2011) Günter P. Wagner et al.   NATURE REVIEWS GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies

(2010) A. Eyre-Walker   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

ForSim: a tool for exploring the genetic architecture of complex traits with controlled truth

(2008) Brian W. Lambert et al.   BIOINFORMATICS

Bootstrap confidence intervals in nonparametric regression with built-in bias correction

(2008) Timothy L. McMurry et al.   STATISTICS & PROBABILITY LETTERS

Assessing the Evolutionary Impact of Amino Acid Mutations in the Human Genome

(2008) Adam R. Boyko et al.   PLoS Genetics