The Circulating Proteinase Inhibitor  -1 Antitrypsin Regulates Neutrophil Degranulation and Autoimmunity

Acute lung injury results from failure of neutrophil de-priming: a new hypothesis

(2012) Nanak R. P. Singh et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Systemic inflammation in COPD in relation to smoking status

(2012) Danielius Serapinas et al.   MULTIDISCIPLINARY RESPIRATORY MEDICINE

Prevalence of α1-antitrypsin deficiency alleles PI*S and PI*Z worldwide and effective screening for each of the five phenotypic classes PI*MS, PI*MZ, PI*SS, PI*SZ, and PI*ZZ: a comprehensive review

(2012) Frederick J. de Serres et al.   Therapeutic Advances in Respiratory Disease

ANCA-associated vasculitis is linked to carriage of the Z allele of  1 antitrypsin and its polymers

(2011) H. Morris et al.   ANNALS OF THE RHEUMATIC DISEASES

Dysregulation of TIM-3-Galectin-9 Pathway in the Cystic Fibrosis Airways

(2011) I. Vega-Carrascal et al.   JOURNAL OF IMMUNOLOGY

Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia–reperfusion injury

(2011) Stefano Toldo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model

(2011) Christian Grimstein et al.   Journal of Translational Medicine

Changes in expression of membrane TNF, NF- B activation and neutrophil apoptosis during active and resolved inflammation

(2010) H. L. Wright et al.   ANNALS OF THE RHEUMATIC DISEASES

Up-regulation of p21 and TNF-alpha is mediated lycorine-induced death of HL-60 cells

(2010) Jing Liu et al.   Cancer Cell International

The acute phase protein response in patients receiving subcutaneous IL-6

(2010) R. E. BANKS et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8

(2010) David A. Bergin et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence for Unfolded Protein Response Activation in Monocytes from Individuals with  -1 Antitrypsin Deficiency

(2010) T. P. Carroll et al.   JOURNAL OF IMMUNOLOGY

Short-Term Monotherapy in HIV-Infected Patients with a Virus Entry Inhibitor Against the gp41 Fusion Peptide

(2010) W.-G. Forssmann et al.   Science Translational Medicine

α 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic β-cells

(2010) Martins Kalis et al.   Islets

Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor

(2009) Sigrun Hope et al.   BIPOLAR DISORDERS

Lung deposition of inhaled  1-proteinase inhibitor in cystic fibrosis and  1-antitrypsin deficiency

(2009) P. Brand et al.   EUROPEAN RESPIRATORY JOURNAL

Exploring the role of CT densitometry: a randomised study of augmentation therapy in  1-antitrypsin deficiency

(2009) A. Dirksen et al.   EUROPEAN RESPIRATORY JOURNAL

Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study

(2009) T. M. L. Eagan et al.   EUROPEAN RESPIRATORY JOURNAL

Combination of alpha-1 antitrypsin and doxycycline suppresses collagen-induced arthritis

(2009) Christian Grimstein et al.   JOURNAL OF GENE MEDICINE

IL-8 Dictates Glycosaminoglycan Binding and Stability of IL-18 in Cystic Fibrosis

(2009) E. P. Reeves et al.   JOURNAL OF IMMUNOLOGY

Comparing two small samples with an unstable, treatment-independent baseline

(2009) Skirmantas Janušonis   JOURNAL OF NEUROSCIENCE METHODS

Elevated TNFα production in whole blood in patients with severe COPD: the potential link to disease severity

(2009) Stephan von Haehling et al.   WIENER KLINISCHE WOCHENSCHRIFT

Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: Mouse models

(2008) Andrei A. Kruglov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

 1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice

(2008) E. C. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Feeder-Free and Efficient Production of Functional Neutrophils from Human Embryonic Stem Cells

(2008) Koichi Saeki et al.   STEM CELLS

TNF-α-induced self expression in human lung endothelial cells is inhibited by native and oxidized α1-antitrypsin

(2007) Devipriya Subramaniyam et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY