PCSK9 is a critical regulator of the innate immune response and septic shock outcome

Berberine inhibits dyslipidemia in C57BL/6 mice with lipopolysaccharide induced inflammation

(2014) Hong-Bo Xiao et al.   Pharmacological Reports

A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function

(2013) Feng Gao et al.   HUMAN MOLECULAR GENETICS

PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment

(2013) Kristian Tveten et al.   JOURNAL OF LIPID RESEARCH

Race and gender variation in response to evoked inflammation

(2013) Jane F Ferguson et al.   Journal of Translational Medicine

Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations

(2013) Janice Mayne et al.   Lipids in Health and Disease

The Potential for PCR Based Testing to Improve Diagnosis and Treatment of Sepsis

(2013) Ngan Lyle et al.   Current Infectious Disease Reports

The effect of rosuvastatin on incident pneumonia: results from the JUPITER trial

(2012) V. Novack et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

An Anti-PCSK9 Antibody Reduces LDL-Cholesterol On Top Of A Statin And Suppresses Hepatocyte SREBP-Regulated Genes

(2012) Liwen Zhang et al.   International Journal of Biological Sciences

Crosstalk between reverse cholesterol transport and innate immunity

(2012) Kathleen M. Azzam et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Plasma PLTP (phospholipid-transfer protein): an emerging role in ‘reverse lipopolysaccharide transport’ and innate immunity

(2011) Thomas Gautier et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Association Between Statins Given in Hospital and Mortality in Pneumonia Patients

(2011) Michael B. Rothberg et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

Continuation of Statin Therapy in Patients with Presumed Infection

(2010) Peter S. Kruger et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Candidate Gene Association Resource (CARe)

(2010) Kiran Musunuru et al.   Circulation-Cardiovascular Genetics

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

(2009) Philippa J. Talmud et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Atorvastatin increases expression of low-density lipoprotein receptor mRNA in human circulating mononuclear cells

(2009) Anothai Pocathikorn et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism

(2009) Melanie J. Scott et al.   HEPATOLOGY

Hepatocyte Nuclear Factor 1α Plays a Critical Role inPCSK9Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine

(2009) Hai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells

(2009) Markey C. McNutt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

(2009) Sekar Kathiresan et al.   NATURE GENETICS

Inhibition of PCSK9: A powerful weapon for achieving ideal LDL cholesterol levels

(2009) D. Steinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Berberine decreases PCSK9 expression in HepG2 cells

(2008) Jamie Cameron et al.   ATHEROSCLEROSIS

S100A8 and S100A9 Mediate Endotoxin-Induced Cardiomyocyte Dysfunction via the Receptor for Advanced Glycation End Products

(2008) John H. Boyd et al.   CIRCULATION RESEARCH

Effect of Plasma Phospholipid Transfer Protein Deficiency on Lethal Endotoxemia in Mice

(2008) Thomas Gautier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APCSK9Missense Variant Associated with a Reduced Risk of Early-Onset Myocardial Infarction

(2008) Sekar Kathiresan   NEW ENGLAND JOURNAL OF MEDICINE

Vasopressin versus Norepinephrine Infusion in Patients with Septic Shock

(2008) James A. Russell et al.   NEW ENGLAND JOURNAL OF MEDICINE